Abstract
Arthur Getis is a pioneer in spatial statistics. His collaboration with Keith Ord has inspired our long-standing collaboration between a geographer and a statistician. Getis often tackled real-world infectious disease problems using spatial statistics, which has motivated our work from time to time. In this paper, we report a 10-week spatial intervention for reducing COVID-19 vaccine hesitancy. In contrast to spatiotemporal modeling, we mapped and detected spatial patterning of vaccination each week in conjunction with the social vulnerability index (SVI). Between week one and week eight, we identified substantial spatial clustering effects of COVID-19 vaccine administrations. These effects were negatively associated with SVI, meaning that the more vulnerable populations were less likely to be vaccinated. This directional effect changed to positive suggesting significant progress from the intervention. Even though we observed some global spatial clustering in the early weeks, low-value clusters or cool spots for vaccine hesitance were no longer present after SVI was controlled. The use of spatial statistics and the SVI can help monitor targeted interventions to reduce vaccination disparities.
Similar content being viewed by others
References
CDC (2022) Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Geospatial Research, Analysis, and Services Program. CDC/ATSDR. Social Vulnerability Index. https://www.atsdr.cdc.gov/placeandhealth/svi/data_documentation_download.html. Accessed 15 Aug 2022
Cliff AD, Ord JK (1981) Spatial processes: models and applications. Pion, London
Flanagan B, Gregory E, Hallisey E, Heitgerd J, Lewis B (2011) A social vulnerability index for disaster management. J Homeland Secur Emerg Manag 8:3. https://doi.org/10.2202/1547-7355.1792
Getis A, Ord JK (1992) The analysis of spatial association by use of distance statistics. Geograph Anal 24:189–206
Getis A, Morrison AC, Grayman WM, Scott TW (2003) Characteristics of the spatial pattern of the dengue vector, Aedes aegypti, in Iquitos, Peru. Am J Trop Med Hyg 69:494–505
Kulldorff M (1997) A spatial scan statistic. Commun Stat Theory Methods 26:1481–1496
Lin G, Zhang T (2004) A method for testing low-value spatial clustering for rare diseases. Acta Tropica 91:279–289
Momplaisir FM, Kuter BJ, Ghadimi F, Browne S, Nkwihoreze H, Feemster KA, Frank I, Faig W, Shen AK, Offit PA, Green-McKenzie J (2021) Racial/ethnic differences in COVID-19 vaccine hesitancy among health care workers in 2 large academic hospitals. JAMA Netw Open 4(8):e2121931. https://doi.org/10.1001/jamanetworkopen.2021.21931
Morrison AC, Astete H, Chapilliquen F, Ramirez-Prada C, Diaz G, Getis A, Gray K, Scott TW (2002) Evaluation of a sampling methodology for rapid assessment of Aedes aegypti infestation levels in Iquitos, Peru. J Med Entomol 41:502–10
Moran PAP (1948) The interpretation of statistical maps. J Roy Stat Soc Ser B 10:243–251
Moran PAP (1950) Notes on continuous stochastic phenomena. Biometrika 37:17–23
Yancy CW (2020) COVID-19 and African Americans. JAMA 323:1891–1892
Zhang T, Lin G (2009) Cluster detection based on spatial associations and iterated residuals in generalized linear mixed models. Biometrics 65:353–360
Zhang T, Lin G (2009) Scan statistics in loglinear models. Comput Stat Data Anal 53:2851–2858
Zhang T, Zhang Z, Lin G (2012) Spatial scan statistics with over dispersion. Stat Med 31:762–774
Zhang T, Lin G (2014) Family of power divergence spatial scan statistics. Comput Stat Data Anal 75:162–178
Zhang T, Lin G (2016) On Moran’s I coefficient under heterogeneity. Comput Stat Data Anal 95:83–94
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Appendix
Appendix
See Table 4.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Lin, G., Zhang, T. Spatial monitoring to reduce COVID-19 vaccine hesitance. J Geogr Syst 26, 249–264 (2024). https://doi.org/10.1007/s10109-023-00437-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10109-023-00437-6
Keywords
- Vaccine hesitance
- Quasi-Poisson model
- Social vulnerable index
- Spatial clustering and clusters
- Spatial scan statistic
- Overdispersion