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Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series

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Abstract

Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroids. The study objective was to detail the clinical effectiveness of low-level laser therapy (LLLT) for the management of OLP unresponsive to standard topical therapy. The authors studied a prospective cohort of 30 patients affected by OLP, who received biostimulation with a 980-nm gallium-aluminum-arsenide (GaAIAs) diode laser (DM980, distributed by DMT S.r.l., Via Nobel 33, 20035, Lissone, Italy). Outcome variables, statistically evaluated, were: the size of lesions; visual analogue score of pain and stability of the therapeutic results in the follow-up period. Eighty-two lesions were treated. We reported significant reduction in clinical scores of the treated lesions and in reported pain. No detailed complications or therapy side effects were observed during the study. As previously reported by our group with a preliminary report, this study suggests that LLLT could be a possible treatment choice for patients with unresponsive symptomatic OLP, also reducing the possible invasiveness correlated with other therapies.

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Authors and Affiliations

  1. Oral Medicine Section, Department of Surgical Sciences, University of Turin, UNITO LINGOTTO DENTAL INSTITUTE c/o Lingotto, Via Nizza 230, 10126, Turin, Italy

    Adriana Cafaro, Paolo Giacomo Arduino, GianLuca Massolini & Roberto Broccoletti

  2. Department of Surgical Sciences and Integrated Diagnostics, Genoa University, Genoa, Italy

    Ercole Romagnoli

Authors
  1. Adriana Cafaro
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  2. Paolo Giacomo Arduino
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  3. GianLuca Massolini
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  4. Ercole Romagnoli
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  5. Roberto Broccoletti
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Correspondence to Paolo Giacomo Arduino.

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Cafaro, A., Arduino, P.G., Massolini, G. et al. Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series. Lasers Med Sci 29, 185–190 (2014). https://doi.org/10.1007/s10103-013-1313-6

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  • DOI: https://doi.org/10.1007/s10103-013-1313-6

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