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Low-level laser therapy supported teeth extractions of two patients receiving IV zolendronate

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Abstract

BRONJ (bisphosphonate-related osteonecrosis of jaws) is a frequently encountered disease, particularly in the maxillofacial region, and a consequence of bisphosphonate use. Treatment of BRONJ remains controversial, as efficiency of medical and surgical approaches as well as a combination of these methods with supportive treatments have not been clearly demonstrated in the literature. In recent years, laser usage alone or in combination with the main therapy methods, has become popular for the treatment of bisphosphonate-related osteo-necrosis of jaws. In this article, we present the successful management of two dental patients who had high potentials for BRONJ development as a result of chemo and radiotherapy combined with IV zoledronic acid application. Multiple consecutive teeth extractions followed with primary wound closure and LLLT applications were performed under high doses of antibiotics prophylaxis. Satisfactory wound healing in both the surrounding soft and hard tissues was achieved. LLLT application combined with atraumatic surgical interventions under antibiotics prophylaxis is a preferable approach in patients with a risk of BRONJ development. Adjunctive effect of LLLT in addition to careful infection control on preventing BRONJ was reported and concluded.

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Authors and Affiliations

  1. Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Hacettepe University, Ankara, Turkey

    Bahadır Kan, Mehmet Ali Altay & Ferda Taşar

  2. Faculty of Medicine, Department of Internal Medicine, Unit of Infectious Disease, Hacettepe University, Ankara, Turkey

    Murat Akova

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  1. Bahadır Kan
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  2. Mehmet Ali Altay
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  3. Ferda Taşar
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  4. Murat Akova
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Correspondence to Bahadır Kan.

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Kan, B., Altay, M.A., Taşar, F. et al. Low-level laser therapy supported teeth extractions of two patients receiving IV zolendronate. Lasers Med Sci 26, 569–575 (2011). https://doi.org/10.1007/s10103-010-0816-7

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  • DOI: https://doi.org/10.1007/s10103-010-0816-7

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