Abstract
Luria’s Alternating Series Test (AST) is a popular bedside graphomotor task used to assess set-shifting both in patients with focal brain damage and with neurodegenerative disease. Several approaches to automate its assessment are available, yet they require digitizers or other electronic devices. However, archived data from the past 60 years are stored only on paper. This pilot study concerns the extraction of the features from the paper version of AST using image processing algorithms.
In this study, AST data from twenty two cases with progressive supranuclear palsy are processed. Each case contains reference data (a pattern sequence drawn by the examiner) and diagnostic data (continuation of the pattern drawn by the patient). Spatial-based features as well as (novel) erosion bar charts (EBC) are extracted from the initial characters of the examiner and patient sequence. The results are evaluated to find parameters that are statistically different between the groups. The results indicate that patients typically write larger characters than examiners, yet their pen-paper pressure is smaller.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Diesfeldt, H.F.A.: Visuographic tests of set shifting and inhibitory control. The contribution of constructional impairments. J. Neuropsychol. 3(1), 93–105 (2009)
Drotár, P., Mekyska, J., Rektorová, I., Masarová, L., Smékal, Z., Faundez-Zanuy, M.: Analysis of in-air movement in handwriting: a novel marker for Parkinson’s disease. Comput. Methods Program Biomed. 117(3), 405–411 (2014). https://doi.org/10.1016/j.cmpb.2014.08.007. ISSN 0169-2607
Golden, C.J., Freshwater, S.M.: Luria-Nebraska neuropsychological battery. In: Understanding Psychological Assessment, pp. 59–75. Springer, Boston, MA (2001)
Kawa, J., Bednorz, A., Stępień, P., Derejczyk, J., Bugdol, M.: Spatial and dynamical handwriting analysis in mild cognitive impairment. Comput. Biol. Med. 82, 21–28 (2017). https://doi.org/10.1016/j.compbiomed.2017.01.004. ISSN 0010-4825
Luria, A.R.: Higher Cortical Functions in Man. Springer Science & Business Media, Heidelberg (2012)
Nackaerts, E., Nieuwboer, A., Farella, E.: Technology-assisted rehabilitation of writing skills in Parkinson’s disease: visual cueing versus intelligent feedback. Parkinson’s Dis. 2017, 1–7 (2017). https://doi.org/10.1155/2017/9198037
Nõmm, S., Toomela, A., Kozhenkina, J., Toomsoo, T.: Quantitative analysis in the digital Luria’s alternating series tests. In: 2016 14th International Conference on Control, Automation, Robotics and Vision (ICARCV), Phuket, pp. 1–6 (2016). https://doi.org/10.1109/ICARCV.2016.7838746
Parsons, T.D.: Neuropsychological assessment 2.0: computer-automated assessments. In: Clinical Neuropsychology and Technology, pp. 47–63. Springer International Publishing (2016). https://doi.org/10.1007/978-3-319-31075-6_4
Phillips, J.G., Stelmach, G.E., Teasdale, N.: What can indices of handwriting quality tell us about Parkinsonian handwriting? Hum. Mov. Sci. 10(2–3), 301–314 (1991). https://doi.org/10.1016/0167-9457(91)90009-M. ISSN 0167-9457
Phillips, J.G., Bradshaw, J.L., Chiu, E., Bradshaw, J.A.: Characteristics of handwriting of patients with Huntington’s disease. Mov. Disord. 9, 521–530 (1994). https://doi.org/10.1002/mds.870090504
Proctor, H.: Revolutionary thinking: a theoretical history of Alexander Luria’s Romantic science (Doctoral dissertation, Birkbeck, University of London) (2016)
Schröter, A., Mergl, R., Bürger, K., Hampel, H., Möller, H.J., Hegerl, U.: Kinematic analysis of handwriting movements in patients with Alzheimer’s disease, mild cognitive impairment, depression and healthy subjects. Dement. Geriatr. Cogn. Disord. 15, 132–142 (2003)
Sitek, E.J., Kawa, J., Stępień, P., Brockhuis, B., Kluj-Kozłowska, K., et al.: Makrografia jako jeden z objawów agrafii wykonawczej u pacjenta z wariantem behawioralnym otępienia czołowo-skroniowego. Pol. Przegl. Neurol. t. 13(Supl. A), s. A100 (2017). ISSN: 1734–5251
Weiner, M., Hynan, L., Rossetti, H., Falkowski, J.: Luria’s three-step test: what is it and what does it tell us? Int. Psychogeriatr. 23(10), 1602–1606 (2011). https://doi.org/10.1017/S1041610211000767
Sitek, E.J., Konkel, A., Dąbrowska, M., Sławek, J.: Utility of Frontal Assessment Battery in detection of neuropsychological dysfunction in Richardson variant of progressive supranuclear palsy. Neurol. Neurochir. Pol. 49(1), 36–40 (2015). https://doi.org/10.1016/j.pjnns.2014.12.002. Epub Dec 9, 2014
Sitek, E.J., Narożańska, E., Konieczna, S., Brockhuis, B., Wieczorek, D., Wszolek, Z.K., Sławek, J.: Drawing analysis in the assessment of patients with neurodegenerative diseases. Neurology 88(2), 218–219 (2017). https://doi.org/10.1212/WNL.0000000000003496
Sitek, E.J., Wieczorek, D., Konkel, A., Dąbrowska, M., Sławek, J.: The pattern of verbal, visuospatial and procedural learning in Richardson variant of progressive supranuclear palsy in comparison to Parkinson’s disease. Psychiatr. Pol. 51(4), 647–659 (2017). https://doi.org/10.12740/PP/OnlineFirst/62804. Epub Aug 29, 2017
Höglinger, G.U., Respondek, G., Stamelou, M., Kurz, C., Josephs, K.A., Lang, A.E., et al.: Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Mov. Disord. 32(6), 853–864 (2017)
Acknowledgement
We would like to thank Andre Woloshuk for his English language corrections.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer International Publishing AG, part of Springer Nature
About this paper
Cite this paper
Stępień, P., Kawa, J., Wieczorek, D., Dąbrowska, M., Sławek, J., Sitek, E.J. (2019). Computer Aided Feature Extraction in the Paper Version of Luria’s Alternating Series Test in Progressive Supranuclear Palsy. In: Pietka, E., Badura, P., Kawa, J., Wieclawek, W. (eds) Information Technology in Biomedicine. ITIB 2018. Advances in Intelligent Systems and Computing, vol 762. Springer, Cham. https://doi.org/10.1007/978-3-319-91211-0_49
Download citation
DOI: https://doi.org/10.1007/978-3-319-91211-0_49
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-91210-3
Online ISBN: 978-3-319-91211-0
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)