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Brown Adipose Tissue: A Human Perspective

  • Chapter
Metabolic Control

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 233))

Abstract

Since 2009, the presence of brown adipose tissue (BAT) in adult humans has been irrefutably proven. It is estimated that active BAT can contribute up to 2.5–5% of resting metabolic rate in humans, suggesting that sustained activation of BAT may alleviate obesity and associated disorders. In the current chapter, the discovery of BAT in adult humans will be discussed. Furthermore, the characteristics of human BAT, methods to visualize the tissue as well as physiological and pharmacological methods to enhance its activity will be stressed.

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  1. Maastricht University, Maastricht, The Netherlands

    Mariëtte R. Boon & Wouter D. van Marken Lichtenbelt

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  1. Mariëtte R. Boon
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  2. Wouter D. van Marken Lichtenbelt
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Correspondence to Wouter D. van Marken Lichtenbelt .

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  1. Helmholtz Center Munich, and Heidelberg University Hospital, Professor and Director, Institute for Diabetes and Cancer IDC, and Joint Heidelberg-IDC Translational Diabetes Program, Neuherberg, Germany

    Stephan Herzig

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Boon, M.R., van Marken Lichtenbelt, W.D. (2015). Brown Adipose Tissue: A Human Perspective. In: Herzig, S. (eds) Metabolic Control. Handbook of Experimental Pharmacology, vol 233. Springer, Cham. https://doi.org/10.1007/164_2015_11

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