[go: up one dir, main page]
Skip to main content
Springer Nature Link
Log in

Three-Dimensional Digital Breast Tomosynthesis in the Early Diagnosis and Detection of Breast Cancer

  • Conference paper
Digital Mammography (IWDM 2006)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 4046))

Included in the following conference series:

  • 1482 Accesses

Abstract

This paper presents doctoral thesis of three-dimensional digital breast tomosynthesis in the early diagnosis and detection of breast cancer. The purpose is to prove that digital breast tomosynthesis has the potential to provide clinically important information, which cannot be obtained with conventional breast imaging methods. Three-dimensional digital breast tomosynthesis seeks to (1) determine whether a mammographic finding is the result of a ‘real’ lesion or the superimposition of normal parenchyma structures, (2) detect subtle changes in breast tissue, which might otherwise be missed, and (3) to reduce the number of biopsies performed as well as verify the correct biopsy target if the procedure is needed. This study presents digital breast tomosynthesis in diagnostic mammography by comparing digital breast tomosynthesis with screenfilm and digital mammograms clinical performance, evaluates Tuned Aperture Computed Tomography capability as a 3D breast reconstruction algorithm in the limited angle tomosynthesis system, and demonstrates technical performance of a real-time amorphous-selenium flat-panel detector in full field digital breast tomosynthesis. The results indicate that breast tomosynthesis has the potential to significantly advance diagnostic mammography. Tomosynthesis of the breast will increase specificity. Study also suggests that tomosynthesis might facilitate the detection of cancers at an earlier stage and a smaller size than is possible in two-dimensional mammography [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Varjonen, M.: Three-dimensional (3D) digital breast tomosynthesis (DBT) in the early diagnosis and detection of breast cancer. Doctoral thesis. Tampere University of Technology publications 594 (2006)

    Google Scholar 

  2. Kopans, D.B.: Digital mammography: Principles, equipment, technique and clinical results. Breast Imaging: RSNA Categorial course in Diagnostic Radiology, 77–82 (2005)

    Google Scholar 

  3. Rafferty, E.A., Georgian-Smith, D., Kopans, D.B., McCarthy, K.A., Hall, D.A., Moore, R., Wu, T.: Comparison of full-field digital tomosynthesis with two view conventional film screen mammography in the prediction of lesion malignancy (abstr.). Radiology, 225–268 (2002)

    Google Scholar 

  4. Lehtimäki, M., Pamilo, M., Raulisto, L., Roiha, M., Kalke, M., Siltanen, S., Ihamäki, T.: Diagnostic clinical benefits of digital spot and digital 3D mammography following analysis of screening findings. In: SPIE Proc., vol. 5029, pp. 698–706 (2003)

    Google Scholar 

  5. Rafferty, E.A.: Breast tomosynthesis. Advances in Digital Radiography: RSNA Categorical Course in Diagnostic Radiology Physics, 219–226 (2003)

    Google Scholar 

  6. Lehtimäki, M., Pamilo, M.: Clinical aspects of diagnostic 3-dimensional mammography. Seminars in Breast Disease 6, 72–77 (2004)

    Google Scholar 

  7. Varjonen, M., Pamilo, M., Raulisto, L.: Clinical benefits of combined three-dimensional digital breast tomosynthesis and ultrasound imaging. In: SPIE Proc., vol. 5745, pp. 562–571 (2005)

    Google Scholar 

  8. Lehtimäki, M., Nelson, M., Lechner, M., Elvecrog, E.: Improved method for diagnosis in clinical mammography with breast tomosynthesis. In: Internatiol Workshop on Digital Mammography (IWDM) (2004)

    Google Scholar 

  9. D’Orsi, C.J., Bassett, L.W., Berg, W.A., Feig, S.A., Jackson, V.P., Kopans, D.B., et al.: Breast imaging reporting and data system. American College of Radiology (2003)

    Google Scholar 

  10. Farria, D.M., Monsees, B.: Screening mammography practise essentials. Radiol. Clin. N. Am. 42, 831–843 (2004)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tampere University of Technology, PL 692, 33101, Tampere, Finland

    Mari Varjonen

  2. Planmed Oy, Asentajankatu 6, 00880, Helsinki, Finland

    Mari Varjonen

Authors
  1. Mari Varjonen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, M13 9PT, Manchester

    Susan M. Astley

  2. Wolfson Medical Vision Lab, University of Oxford, UK

    Michael Brady

  3. Imaging Science and Biomedical Engineeering, University of Manchester, Oxford Road, M13 9PT, Manchester, UK

    Chris Rose

  4. Department of Computer Science, University of Wales, Aberystwyth, UK

    Reyer Zwiggelaar

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Varjonen, M. (2006). Three-Dimensional Digital Breast Tomosynthesis in the Early Diagnosis and Detection of Breast Cancer. In: Astley, S.M., Brady, M., Rose, C., Zwiggelaar, R. (eds) Digital Mammography. IWDM 2006. Lecture Notes in Computer Science, vol 4046. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11783237_22

Download citation

  • DOI: https://doi.org/10.1007/11783237_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-35625-7

  • Online ISBN: 978-3-540-35627-1

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics