Main menu
Common skin conditions
NEWS
Check out what's new with DermNet
Read more
Quick links
Author: Hon A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand, 2003.
" data-index="1" alt="Go to Introduction
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(1 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Introduction
" data-index="2" alt="Go to Characteristics of fungi
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(2 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Characteristics of fungi
" data-index="3" alt="Go to Superficial fungal infections
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(3 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Superficial fungal infections
" data-index="4" alt="Go to Subcutaneous fungal infections
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(4 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Subcutaneous fungal infections
" data-index="5" alt="Go to Systemic fungal infections
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(5 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Systemic fungal infections
" data-index="6" alt="Go to Antifungal drug resistance
" onclick="event.preventDefault();document.getElementsByTagName('h2')[(6 - 1)].scrollIntoView({behavior: 'smooth',block: 'start'});">Antifungal drug resistance
E-lecture
Fungal infections of the skin are also known as ‘mycoses’. They are common and generally mild. However, in very sick or otherwise immune suppressed people, fungi can sometimes cause severe disease.
Tinea capitis
Tinea cruris
Chronic candida paronychia
Fungi are parasites or saprophytes and live off living or dead organic matter.
Mycologists identify and classify fungi according to their appearance by microscopy and in culture, and by the method of reproduction, which may be sexual or asexual.
Growing fungi have branched filaments called hyphae, which make up the mycelium (like branches are part of a tree). Some fungi are compartmented by cross-walls (called septae).
Arthrospores are made up of fragments of the hyphae, breaking off at the septae. Asexual spores (conidia) form on conidiophores. The sexual reproductive phase of many fungi is unknown; these are ‘fungi imperfecta’ and include those which infect humans.
Yeasts form a subtype of fungus characterised by clusters of round or oval cells. These bud out similar cells from their surface to divide and propagate. In some circumstances, they form a chain of cells called a pseudomycelium.
These affect the outer layers of the skin, the nails and hair. The main groups of fungi causing superficial fungal infections are:
These involve the deeper layers of the skin (the dermis, subcutaneous tissue and even bone). The causative organisms live in the soil on rotting vegetation. They can get pricked into the skin as a result of an injury but usually stay localised at the site of implantation. Deeper skin infections include:
Systemic mycoses may result from breathing in the spores of fungi, which live in the soil or rotting vegetation, or present as an opportunistic disease in immunocompromised individuals.
Although uncommon, some may infect healthy individuals. The result is most often a mild infection and long-lasting resistance to further attack, but occasionally these infections are more severe and chronic (especially in the immune suppressed). The organisms causing systemic fungal infections include:
Other systemic mycoses only infect those who are already sick or with an immunodeficiency disorder (they are ‘opportunists’). Repeated infection may occur. Risks for systemic mycoses include:
In recent years, both topical and oral allylamine and triazole antifungal drug resistance has become a problem, particularly in the Indian subcontinent.
Extensive therapy-resistant dermatophyte infection should prompt this as a possible problem. Where available, fungal culture and estimation of drug minimum inhibitory concentration determined to guide appropriate medication.
For more information, see antifungal drug resistance.
TrendMD recommendations failed to load. Please refresh the page.