ITGB7

ITGB7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BRQ, 3V4P, 3V4V
Dynodwyr
Cyfenwau	ITGB7, integrin subunit beta 7
Dynodwyr allanol	OMIM: 147559 HomoloGene: 20247 GeneCards: ITGB7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • virus receptor activity • metal ion binding • GO:0001948, GO:0016582 protein binding • cell adhesion molecule binding • integrin binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • bilen • receptor complex • Cellbilen • cell surface • integrin complex • extracellular exosome • integrin alpha4-beta7 complex • focal adhesion Prosesau biolegol • T cell migration • heterotypic cell-cell adhesion • cell-matrix adhesion involved in ameboidal cell migration • extracellular matrix organization • receptor clustering • cell adhesion • regulation of immune response • leukocyte tethering or rolling • integrin-mediated signaling pathway • viral entry into host cell • substrate adhesion-dependent cell spreading • cell-matrix adhesion • leukocyte migration • cell migration • cell adhesion mediated by integrin Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3695	n/a
Ensembl	ENSG00000139626	n/a
UniProt	P26010	n/a
RefSeq (mRNA)	NM_000889	n/a
RefSeq (protein)	NP_000880	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ITGB7 yw ITGB7 a elwir hefyd yn Integrin subunit beta 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.13.

Llyfryddiaeth

• "Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster. ". Nat Struct Biol. 2003. PMID 14608374.
• "The microenvironment of human Peyer's patches inhibits the increase in CD38 expression associated with the germinal center reaction. ". J Immunol. 2001. PMID 11160270.
• "Maturation-dependent expression and function of the CD49d integrin on monocyte-derived human dendritic cells. ". J Immunol. 2000. PMID 11035069.
• "Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes. ". J Immunol. 1993. PMID 7689608.
• "Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression.". Am J Respir Cell Mol Biol. 1994. PMID 7509610.