CD2

CD2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CDB, 1GYA, 1HNF, 1L2Z, 1QA9, 2J6O, 2J7I
Dynodwyr
Cyfenwau	CD2, LFA-2, SRBC, T11, CD2 molecule
Dynodwyr allanol	OMIM: 186990 HomoloGene: 1338 GeneCards: CD2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • signaling receptor binding • signaling receptor activity • GO:0003823, GO:0051635 antigen binding • protein kinase binding • receptor tyrosine kinase binding • protein self-association Cydrannau o'r gell • integral component of membrane • bilen • cell-cell junction • anchored component of plasma membrane • integral component of plasma membrane • extracellular region • cell surface • cytoplasmic side of plasma membrane • external side of plasma membrane • Cellbilen • GO:0009327 protein-containing complex • membrane raft Prosesau biolegol • positive regulation of myeloid dendritic cell activation • heterotypic cell-cell adhesion • natural killer cell activation • membrane raft polarization • cell surface receptor signaling pathway • cell adhesion • positive regulation of tumor necrosis factor production • T cell activation • leukocyte migration • regulation of T cell differentiation • GO:0097285 apoptotic process • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	914	n/a
Ensembl	ENSG00000116824	n/a
UniProt	P06729 Q53F96	n/a
RefSeq (mRNA)	NM_001767 NM_001328609	n/a
RefSeq (protein)	NP_001315538 NP_001758 NP_001758.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD2 yw CD2 a elwir hefyd yn CD2 antigen (P50), sheep red blood cell receptor a CD2 molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD2.

• T11
• SRBC
• LFA-2

Llyfryddiaeth

• "A candidate gene study identifies a haplotype of CD2 as novel susceptibility factor for systemic sclerosis. ". Clin Exp Rheumatol. 2016. PMID 27385538.
• "A CD2 high-expressing stress-resistant human plasmacytoid dendritic-cell subset. ". Immunol Cell Biol. 2016. PMID 26791160.
• "Family-based analysis identified CD2 as a susceptibility gene for primary open angle glaucoma in Chinese Han population. ". J Cell Mol Med. 2014. PMID 24597656.
• "High levels of CD2 expression identify HIV-1 latently infected resting memory CD4+ T cells in virally suppressed subjects. ". J Virol. 2013. PMID 23760244.
• "CD2 promotes human natural killer cell membrane nanotube formation.". PLoS One. 2012. PMID 23112830.