ACAD8

ACAD8
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RX0
Dynodwyr
Cyfenwau	ACAD8, ACAD-8, ARC42, acyl-CoA dehydrogenase family member 8, IBDH
Dynodwyr allanol	OMIM: 604773 HomoloGene: 8662 GeneCards: ACAD8
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity, acting on the CH-CH group of donors • oxidoreductase activity • acyl-CoA dehydrogenase activity • flavin adenine dinucleotide binding Cydrannau o'r gell • mitochondrial matrix • mitocondria Prosesau biolegol • valine catabolic process • branched-chain amino acid catabolic process • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • lipid metabolism Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27034	n/a
Ensembl	ENSG00000151498	n/a
UniProt	Q9UKU7	n/a
RefSeq (mRNA)	NM_014384	n/a
RefSeq (protein)	NP_055199	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ACAD8 yw ACAD8 a elwir hefyd yn Acyl-CoA dehydrogenase family member 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q25.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACAD8.

• ARC42
• ACAD-8

Llyfryddiaeth

• "Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans. ". Mol Genet Metab. 2002. PMID 12359132.
• "Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism. ". Am J Hum Genet. 2000. PMID 11013134.
• "A novel ACAD8 mutation in asymptomatic patients with isobutyryl-CoA dehydrogenase deficiency and a review of the ACAD8 mutation spectrum. ". Clin Genet. 2015. PMID 24635911.
• "Structures of isobutyryl-CoA dehydrogenase and enzyme-product complex: comparison with isovaleryl- and short-chain acyl-CoA dehydrogenases. ". J Biol Chem. 2004. PMID 14752098.
• "Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family.". Biochim Biophys Acta. 1999. PMID 10524212.