Association between Chromatin Structural Organization of Peripheral Blood Neutrophils and Self-Perceived Mental Stress: Gray-Level Co-occurrence Matrix Analysis, 2021
Methods based on the evaluation of textural patterns in microscopy, such as the "gray-level co-oc... more Methods based on the evaluation of textural patterns in microscopy, such as the "gray-level co-occurrence matrix" (GLCM) analysis are modern and innovative computer and mathematical algorithms that can be used to quantify subtle structural changes in cells and their organelles. Potential application of GLCM method in the fields of psychophysiology and psychiatry to this date has not been systematically investigated. The main objective of our study was to test the existence and strength of the association between chromatin structural organization of peripheral blood neutrophils and levels of self-perceived mental stress. The research was done on a sample of 100 healthy student athletes, and the Depression, Anxiety, and Stress Scales (DASS-21) were used for the estimation of psychological distress. Chromatin textural homogeneity and uniformity were negatively correlated (p < 0.01) with mental distress and had relatively good discriminatory power in differentiating participants with normal and elevated stress levels. As an addition, we propose the creation of a machine learning model based on binomial logistic regression that uses these and other GLCM features to predict stress elevation. To the best of our knowledge, these results are one of the first to establish the link between neutrophil chromatin structural organization quantified by the GLCM method and indicators of normal psychological functioning.
... 6, br. 1-2, str. 35-40. jezik rada: srpski saoptenje. Faktori koji određuju seksualno ponaa... more ... 6, br. 1-2, str. 35-40. jezik rada: srpski saoptenje. Faktori koji određuju seksualno ponaanje mladih. Neić Dejan a , Jović Stevan b , Nikolić Gordana c , Mrvaljević Milutin a , Lačković Maja a. ... VBS. Marić, J. (1998) Ljubav, seks i depresija - mali priručnik za srećniji ivot. ...
Cervix cancer occupies the third place after breast cancer and colon cancer white malignant tumor... more Cervix cancer occupies the third place after breast cancer and colon cancer white malignant tumors of the body uterus are in the fourth place. It is the most frequent tumor of female sexual organs. Aim of this study is to show the percentage of mortality of women caused ...
The prospective, simple randomized study assesses the effect of focused extracorporeal shock wave... more The prospective, simple randomized study assesses the effect of focused extracorporeal shock wave therapy (f-ESWT) on pain intensity and calcification size compared to the application of ultrasound physical therapy in treating patients with calcar calcanei. A total of 124 patients diagnosed with calcar calcanei were consecutively included in the study. The patients were divided into two groups: the experimental group ( n = 62 ), which included the patients treated with f-ECWT, and the control group ( n = 62 ), consisting of patients treated with the standard ultrasound therapy method. The experimental group’s patients received ten therapy applications spaced seven days apart. The patients in the control group had ten ultrasound treatments on ten consecutive days over two weeks. All patients in both groups were tested using the Visual Analog Scale (VAS) to measure pain intensity before the beginning and at the end of treatment. The size of the calcification was assessed in all patien...
Association between Chromatin Structural Organization of Peripheral Blood Neutrophils and Self-Perceived Mental Stress: Gray-Level Co-occurrence Matrix Analysis, 2021
Methods based on the evaluation of textural patterns in microscopy, such as the "gray-level co-oc... more Methods based on the evaluation of textural patterns in microscopy, such as the "gray-level co-occurrence matrix" (GLCM) analysis are modern and innovative computer and mathematical algorithms that can be used to quantify subtle structural changes in cells and their organelles. Potential application of GLCM method in the fields of psychophysiology and psychiatry to this date has not been systematically investigated. The main objective of our study was to test the existence and strength of the association between chromatin structural organization of peripheral blood neutrophils and levels of self-perceived mental stress. The research was done on a sample of 100 healthy student athletes, and the Depression, Anxiety, and Stress Scales (DASS-21) were used for the estimation of psychological distress. Chromatin textural homogeneity and uniformity were negatively correlated (p < 0.01) with mental distress and had relatively good discriminatory power in differentiating participants with normal and elevated stress levels. As an addition, we propose the creation of a machine learning model based on binomial logistic regression that uses these and other GLCM features to predict stress elevation. To the best of our knowledge, these results are one of the first to establish the link between neutrophil chromatin structural organization quantified by the GLCM method and indicators of normal psychological functioning.
... 6, br. 1-2, str. 35-40. jezik rada: srpski saoptenje. Faktori koji određuju seksualno ponaa... more ... 6, br. 1-2, str. 35-40. jezik rada: srpski saoptenje. Faktori koji određuju seksualno ponaanje mladih. Neić Dejan a , Jović Stevan b , Nikolić Gordana c , Mrvaljević Milutin a , Lačković Maja a. ... VBS. Marić, J. (1998) Ljubav, seks i depresija - mali priručnik za srećniji ivot. ...
Cervix cancer occupies the third place after breast cancer and colon cancer white malignant tumor... more Cervix cancer occupies the third place after breast cancer and colon cancer white malignant tumors of the body uterus are in the fourth place. It is the most frequent tumor of female sexual organs. Aim of this study is to show the percentage of mortality of women caused ...
The prospective, simple randomized study assesses the effect of focused extracorporeal shock wave... more The prospective, simple randomized study assesses the effect of focused extracorporeal shock wave therapy (f-ESWT) on pain intensity and calcification size compared to the application of ultrasound physical therapy in treating patients with calcar calcanei. A total of 124 patients diagnosed with calcar calcanei were consecutively included in the study. The patients were divided into two groups: the experimental group ( n = 62 ), which included the patients treated with f-ECWT, and the control group ( n = 62 ), consisting of patients treated with the standard ultrasound therapy method. The experimental group’s patients received ten therapy applications spaced seven days apart. The patients in the control group had ten ultrasound treatments on ten consecutive days over two weeks. All patients in both groups were tested using the Visual Analog Scale (VAS) to measure pain intensity before the beginning and at the end of treatment. The size of the calcification was assessed in all patien...
Uploads
Papers