| dbo:abstract
|
- Atrolysin A (EC 3.4.24.1) is an enzyme that is one of six hemorrhagic toxins found in the venom of western diamondback rattlesnake. This endopeptidase has a length of 419 amino acid residues. The metalloproteinase disintegrin-like domain and the cysteine-rich domain of the enzyme are responsible for the enzyme's hemorrhagic effects on organisms via inhibition of platelet aggregation. This enzyme catalyzes the following chemical reactions:
* cleavage of peptide bonds between amino acid residues Asn3-Gln4, His5-Leu6, His10-Leu11, Ala14-Leu15 and Tyr16-Leu17 in the insulin B chain
* removal of the C-terminal Leu from small peptides (en)
- . Atrolisin A (bahasa Inggris: atrolysin A, Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin, Crotalus atrox alpha-proteinase, Crotalus atrox metalloproteinase, Atroxase, ALA, EC 3.4.24.1) merupakan enzim yang diisolasi dari bisa ular western diamondback rattlesnake berjenis . ALA mengiris ikatan peptida pada antara gugus Asn3-Gln, His5-Leu, His10-Leu, Ala14-Leu dan Tyr16-Leu pada molekul insulin rantai B dan melepaskan atom C asam amino Leu yang terikat pada peptida. ALA merupakan protease yang tidak menyebabkan pendarahan, melainkan memiliki sifat fibrinolitik dengan aktivitas hidrolisis fibrinogen pada rantai A diikuti dengan pengirisan rantai B, dan dan rekanalisasi. bisa mentah bahkan menginduksi penggumpalan keping darah. (in)
- アトロリシンA(Atrolysin A、EC 3.4.24.1)は、酵素である。この酵素は、インスリンB鎖のAsn3-Gin、His5-Leu、His10-Leu、Ala14-Leu、Tyr16-Leu結合を切断する反応、また小ペプチドからC末端のロイシンを除去する反応を触媒する。 このエンドペプチダーゼは、ニシダイヤガラガラヘビの持つ6つの出血毒のうちの1つである。 (ja)
|
| dbo:ecNumber
| |
| dbo:thumbnail
| |
| dbo:wikiPageID
| |
| dbo:wikiPageLength
|
- 10428 (xsd:nonNegativeInteger)
|
| dbo:wikiPageRevisionID
| |
| dbo:wikiPageWikiLink
| |
| dbp:casNumber
| |
| dbp:ecNumber
| |
| dbp:ecnumber
| |
| dbp:iubmbEcNumber
| |
| dbp:name
|
- Zinc metalloproteinase-disintegrin-like atrolysin-A (en)
- Atrolysin A (en)
|
| dbp:organism
| |
| dbp:symbol
| |
| dbp:taxid
| |
| dbp:uniprot
| |
| dbp:wikiPageUsesTemplate
| |
| dcterms:subject
| |
| gold:hypernym
| |
| rdf:type
| |
| rdfs:comment
|
- アトロリシンA(Atrolysin A、EC 3.4.24.1)は、酵素である。この酵素は、インスリンB鎖のAsn3-Gin、His5-Leu、His10-Leu、Ala14-Leu、Tyr16-Leu結合を切断する反応、また小ペプチドからC末端のロイシンを除去する反応を触媒する。 このエンドペプチダーゼは、ニシダイヤガラガラヘビの持つ6つの出血毒のうちの1つである。 (ja)
- Atrolysin A (EC 3.4.24.1) is an enzyme that is one of six hemorrhagic toxins found in the venom of western diamondback rattlesnake. This endopeptidase has a length of 419 amino acid residues. The metalloproteinase disintegrin-like domain and the cysteine-rich domain of the enzyme are responsible for the enzyme's hemorrhagic effects on organisms via inhibition of platelet aggregation. This enzyme catalyzes the following chemical reactions: (en)
- . Atrolisin A (bahasa Inggris: atrolysin A, Crotalus atrox metalloendopeptidase a; hemorrhagic toxin a; Crotalus atrox α-proteinase; Crotalus atrox proteinase; bothropasin, Crotalus atrox alpha-proteinase, Crotalus atrox metalloproteinase, Atroxase, ALA, EC 3.4.24.1) merupakan enzim yang diisolasi dari bisa ular western diamondback rattlesnake berjenis . (in)
|
| rdfs:label
|
- Atrolysin A (en)
- Atrolisin A (in)
- アトロリシンA (ja)
|
| owl:sameAs
| |
| prov:wasDerivedFrom
| |
| foaf:depiction
| |
| foaf:isPrimaryTopicOf
| |
| foaf:name
| |
| is dbo:wikiPageRedirects
of | |
| is dbo:wikiPageWikiLink
of | |
| is foaf:primaryTopic
of | |
