Atomically detailed simulations were used to assess the performance of zeolite imidazolate framew... more Atomically detailed simulations were used to assess the performance of zeolite imidazolate frameworks (ZIFs) for separation of CH4/H2, CO2/CH4, and CO2/H2 mixtures to provide information for material selection in adsorbent and membrane designs. Adsorption ...
Background : Uterine rupture during labor is a serious and uncommon obstetrical complication that... more Background : Uterine rupture during labor is a serious and uncommon obstetrical complication that can lead to severe prognosis for the mother and her child unless immediately diagnosed and treated. Uterine rupture may occur as a result of preexisting injury or anomaly, and it may be associated with trauma or it may complicate labor in a previously unscarred uterus. Most spontaneous uterine rupture occurs during labor in parturient with a scarred uterus, and they are much rarely seen on an unscarred uterus. Case Presentation: We report the case of a uterine rupture on unscarred uterus in a 33 year old woman after a labor induced by intravenous ocytocine injection. Conclusion: Despite being very rare, rupture incidence is possible on unscarred uterus. Early diagnosis of unscarred uterine rupture along with an immediate medical intervention and the development of neonatal care units will decrease the maternal and neonatal mortality and morbidity.The reduction of multiparity and unneces...
Objectives: The aim of the study was detecting the distribution of patients who performed laparos... more Objectives: The aim of the study was detecting the distribution of patients who performed laparoscopy and hysteroscopy because of infertility, assessing the results of operations, making the demographic analysis, and determining the importance of endoscopic operations. Methods: Between the years of 2008 – 2011, after laparoscopy and hysteroscopy application, the 495 primary and 170 secondary infertile patients with primary infertility were retrospectively analyzed..Following operations, patients were examined in terms of age, duration and type of infertility, presence of male factor and the results of laparoscopic and hysteroscopic surgery. Results: . In our study pathological results were obtained in 55.9 % of patients in laparoscopic operations and 41.3 % of patients in hysteroscopic operations. According to the results of laparoscopic operations 44.1 % of patients were found to be normal. Bilateral and unilateral tubal occlusion was detected in 18.7 % and 11.6 % of patients respe...
Aim. Examine the clinical indications for hysterectomy operations performed in our clinic and put... more Aim. Examine the clinical indications for hysterectomy operations performed in our clinic and put forward the histopathologic diagnosis of hysterectomy materials. Method. 223 total abdominal hysterectomy cases performed between January 2010-January 2013 were retrospectively evaluated. Age, menopausal status, operation indication, the operation data and the results of materials pathological examination were analyzed. Results. The mean age of the patients was 49.3±5.4. All cases underwent total abdominal hysterectomy. 76.2% of the patients was performed bilateral oopherectomy, 17.4% of the patients was performed unilateral oopherectomy, 6.2% of the patients was performed only hysterectomy. Between the hysterectomy indications the most common one was leiyomyom with 138 patients (61.8 %). The other indications were dysfunctional uterine bleeding with 38 patients (17%), adnexal masses with 37 patients (16.5%), pelvic organ prolapse with 10 patients (4.4%). As the result of histopathologi...
Objectives: Histopathological evaluation and demographic analysis of patients with abnormal cervi... more Objectives: Histopathological evaluation and demographic analysis of patients with abnormal cervical smears Methods: According to the cytologic screening programme used in our clinic, colposcopic biopsy and treatment results of 1015 patients with anormal cervical cytology, between the years 2005 - 2011, examined retrospectively. Results: In our study, anormal cytology results were defined as ASC-US 63.4 %, LGSIL 30.3 %, HGSIL 5.2 %, ASC-H 0.7 %, AGUS 0.4 %. Histopathologically in ASC-US group, low-grade lesions in the rate of 51.3 % was determined. This ratio is an indication of the importance of ASC-US follow-up. High-grade lesion detection rates in HGSİL and LGSİL groups was similar to literature data. Especially in HGSİL cases, high-grade lesion detection rate of 66.03 % shows the need for not to delay in treatment. Conclusions: As a result, with appropriate follow-up and treatment methods cervical cytological abnormalities can be controlled before advance to invasive cervical ca...
It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The ai... more It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The aim of the study was to evaluate whether this risk was elevated in young women with diminished ovarian reserve (DOR). A hundred women with DOR and 100 women with normal ovarian reserve (NOR) attending the infertility unit at Suleymaniye Maternity, Research &Training Hospital, were enrolled in the study. CVD risk markers such as insulin resistance (defined by the homeostasis model assessment ratio [HOMA-IR]), C-reactive protein (CRP), low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), and triglyceride (TG) were assessed. HOMA-IR, CRP, TG, LDL levels were higher and HDL was lower among patients with DOR compared to the controls (p < 0.05 for all). There were positive associations between DOR and HOMA-IR, CRP, TG, LDL levels and a negative correlation with HDL (p < 0.05 for all). However, multivariate logistic regression analysis showed that HOMA-IR, CRP, TG, and HDL were independent variables that were associated with DOR. CVD risk markers were increased in women with DOR. Further studies with larger groups are needed to investigate the nature of the link in these patients.
The aim of our study was to evaluate the level of knowledge of the adolescent girls who presented... more The aim of our study was to evaluate the level of knowledge of the adolescent girls who presented to our clinic about human papilloma virus (HPV) infection and HPV vaccine. Five hundred and one adolescent girls aged between 13 and 18 years who presented to the gynecology outpatient clinic between March 2012 and March 2013 were asked to answer the questions of the questionnaire about HPV and HPV vaccine. The "Participant Information Form" and "HPV Information Assessment Form" were used by examination of the related literature by the investigators. The data obtained were entered into the computer using the SPSS 16.5 program and evaluated. Descriptive statistics were shown with mean, standard deviation, number and percentage values. The mean age of 501 subjects who were included into the study was 15.92 years. 390 subjects (77.8%) who were included in the study had no information about HPV. 111 subjects (22.2%) stated that they heard of HPV before or had information about HPV. The mean age of the subjects who had information about human papilloma virus was found to be 16.52 years. The mean age of 390 subjects (77.8%) who had no information about human papilloma virus was 15.75 years. It was found that only one of the subjects (0.9%) was vaccinated with HPV vaccine. When the subjects who did not wish to be vaccinated were asked for the reason, 40.9% stated that the reason was inadequate information, 26.4% stated that the reason was high cost, 16.4% stated that the reason was the fact that they did not consider themselves at risk and 16.4% stated that the reason was the fact that they were afraid of side effects. In our study, it was found that the adolescent girls who constituted our study group had insufficient information about HPV and HPV vaccine. Verbal, written and visual communication tools and internet should be used intensively and efficiently for the objective of introducing HPV vaccine and teaching the precautions related with prevention of cervix cancer in terms of public health. Primarily pediatrician and gynecologists and family physicians who give service for the adolescence age group should be supported to develop appropriate attitudes and behaviors related with HPV vaccine and infection.
The European Journal of Contraception and Reproductive Health Care, 2014
This study evaluated the clinical outcomes and safety of treating caesarean scar pregnancy (CSP) ... more This study evaluated the clinical outcomes and safety of treating caesarean scar pregnancy (CSP) by means of suction curettage followed when required by Foley tamponade, with or without methotrexate (MTX) therapy preceding the curettage. Twenty-five patients with CSP were identified between August 2008 and April 2012. The first team of doctors treated Group A patients (n = 11) with systemic MTX followed by dilatation and suction curettage whereas the second team of doctors carried out only a suction curettage on women of Group B (n = 14). If uncontrolled vaginal bleeding occurred in either group during or after the operation, a Foley catheter, guided by real time transabdominal ultrasound, was placed in the uterine cavity against the site where the CSP had been implanted. Clinical outcomes in the two groups - including mean estimated blood loss, major complication rate, and hospital length of stay - were comparable. Surgeons used Foley catheter balloons for tamponade in six of the 11 patients in Group A and in seven of the 14 patients in Group B. Treatment was successful in ten of 11 cases in group A and 13 of 14 cases in group B. Group B's mean duration of treatment (2.36 ± 0.49 days) was significantly shorter than that of Group A (14.45 ± 4.96 days; p < 0.001). Suction curettage, followed when needed by Foley catheter tamponade, is an effective treatment for CSP.
Journal of the Turkish German Gynecological Association, 2014
To evaluate the natural history of isolated muscular ventricular septal (m-VSD) defects during ge... more To evaluate the natural history of isolated muscular ventricular septal (m-VSD) defects during gestation and up to 1 year postnatally, as well as the association with chromosomal anomalies. Between August 2007 and July 2012, 76 fetuses with isolated m-VSDs represented the study population. The following variables were evaluated: site and size of the m-VSDs, presence of chromosomal anomalies, pregnancy outcome, and spontaneous closure rate from diagnosis up to 1 year postnatally. Of the 76 cases with m-VSD, 1 fetus died after birth and 31 cases were lost to follow-up after birth. Thus, a total of 44 fetuses reached their first year of postnatal life, and these cases were available for analysis. Three (6.8%) of 44 defects closed spontaneously in utero, 33 (75%) closed within 1 year, and 8 (18.2%) remained patent. Overall, spontaneous closure occurred more frequently in the apical defects, but no significant difference was found for spontaneous closure between the mid-muscular and apical defects (p>0.05). Also, 83.8% (36 of 44) of defects ≤3 mm closed during gestation or the first year of life. We infer that m-VSDs have a high spontaneous closure rate during the first year of life. Also, small m-VSDs frequently close spontaneously.
Atomically detailed simulations were used to assess the performance of zeolite imidazolate framew... more Atomically detailed simulations were used to assess the performance of zeolite imidazolate frameworks (ZIFs) for separation of CH4/H2, CO2/CH4, and CO2/H2 mixtures to provide information for material selection in adsorbent and membrane designs. Adsorption ...
Background : Uterine rupture during labor is a serious and uncommon obstetrical complication that... more Background : Uterine rupture during labor is a serious and uncommon obstetrical complication that can lead to severe prognosis for the mother and her child unless immediately diagnosed and treated. Uterine rupture may occur as a result of preexisting injury or anomaly, and it may be associated with trauma or it may complicate labor in a previously unscarred uterus. Most spontaneous uterine rupture occurs during labor in parturient with a scarred uterus, and they are much rarely seen on an unscarred uterus. Case Presentation: We report the case of a uterine rupture on unscarred uterus in a 33 year old woman after a labor induced by intravenous ocytocine injection. Conclusion: Despite being very rare, rupture incidence is possible on unscarred uterus. Early diagnosis of unscarred uterine rupture along with an immediate medical intervention and the development of neonatal care units will decrease the maternal and neonatal mortality and morbidity.The reduction of multiparity and unneces...
Objectives: The aim of the study was detecting the distribution of patients who performed laparos... more Objectives: The aim of the study was detecting the distribution of patients who performed laparoscopy and hysteroscopy because of infertility, assessing the results of operations, making the demographic analysis, and determining the importance of endoscopic operations. Methods: Between the years of 2008 – 2011, after laparoscopy and hysteroscopy application, the 495 primary and 170 secondary infertile patients with primary infertility were retrospectively analyzed..Following operations, patients were examined in terms of age, duration and type of infertility, presence of male factor and the results of laparoscopic and hysteroscopic surgery. Results: . In our study pathological results were obtained in 55.9 % of patients in laparoscopic operations and 41.3 % of patients in hysteroscopic operations. According to the results of laparoscopic operations 44.1 % of patients were found to be normal. Bilateral and unilateral tubal occlusion was detected in 18.7 % and 11.6 % of patients respe...
Aim. Examine the clinical indications for hysterectomy operations performed in our clinic and put... more Aim. Examine the clinical indications for hysterectomy operations performed in our clinic and put forward the histopathologic diagnosis of hysterectomy materials. Method. 223 total abdominal hysterectomy cases performed between January 2010-January 2013 were retrospectively evaluated. Age, menopausal status, operation indication, the operation data and the results of materials pathological examination were analyzed. Results. The mean age of the patients was 49.3±5.4. All cases underwent total abdominal hysterectomy. 76.2% of the patients was performed bilateral oopherectomy, 17.4% of the patients was performed unilateral oopherectomy, 6.2% of the patients was performed only hysterectomy. Between the hysterectomy indications the most common one was leiyomyom with 138 patients (61.8 %). The other indications were dysfunctional uterine bleeding with 38 patients (17%), adnexal masses with 37 patients (16.5%), pelvic organ prolapse with 10 patients (4.4%). As the result of histopathologi...
Objectives: Histopathological evaluation and demographic analysis of patients with abnormal cervi... more Objectives: Histopathological evaluation and demographic analysis of patients with abnormal cervical smears Methods: According to the cytologic screening programme used in our clinic, colposcopic biopsy and treatment results of 1015 patients with anormal cervical cytology, between the years 2005 - 2011, examined retrospectively. Results: In our study, anormal cytology results were defined as ASC-US 63.4 %, LGSIL 30.3 %, HGSIL 5.2 %, ASC-H 0.7 %, AGUS 0.4 %. Histopathologically in ASC-US group, low-grade lesions in the rate of 51.3 % was determined. This ratio is an indication of the importance of ASC-US follow-up. High-grade lesion detection rates in HGSİL and LGSİL groups was similar to literature data. Especially in HGSİL cases, high-grade lesion detection rate of 66.03 % shows the need for not to delay in treatment. Conclusions: As a result, with appropriate follow-up and treatment methods cervical cytological abnormalities can be controlled before advance to invasive cervical ca...
It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The ai... more It has been widely known that cardiovascular disease (CVD) risk is increased in menopause. The aim of the study was to evaluate whether this risk was elevated in young women with diminished ovarian reserve (DOR). A hundred women with DOR and 100 women with normal ovarian reserve (NOR) attending the infertility unit at Suleymaniye Maternity, Research &Training Hospital, were enrolled in the study. CVD risk markers such as insulin resistance (defined by the homeostasis model assessment ratio [HOMA-IR]), C-reactive protein (CRP), low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), and triglyceride (TG) were assessed. HOMA-IR, CRP, TG, LDL levels were higher and HDL was lower among patients with DOR compared to the controls (p < 0.05 for all). There were positive associations between DOR and HOMA-IR, CRP, TG, LDL levels and a negative correlation with HDL (p < 0.05 for all). However, multivariate logistic regression analysis showed that HOMA-IR, CRP, TG, and HDL were independent variables that were associated with DOR. CVD risk markers were increased in women with DOR. Further studies with larger groups are needed to investigate the nature of the link in these patients.
The aim of our study was to evaluate the level of knowledge of the adolescent girls who presented... more The aim of our study was to evaluate the level of knowledge of the adolescent girls who presented to our clinic about human papilloma virus (HPV) infection and HPV vaccine. Five hundred and one adolescent girls aged between 13 and 18 years who presented to the gynecology outpatient clinic between March 2012 and March 2013 were asked to answer the questions of the questionnaire about HPV and HPV vaccine. The "Participant Information Form" and "HPV Information Assessment Form" were used by examination of the related literature by the investigators. The data obtained were entered into the computer using the SPSS 16.5 program and evaluated. Descriptive statistics were shown with mean, standard deviation, number and percentage values. The mean age of 501 subjects who were included into the study was 15.92 years. 390 subjects (77.8%) who were included in the study had no information about HPV. 111 subjects (22.2%) stated that they heard of HPV before or had information about HPV. The mean age of the subjects who had information about human papilloma virus was found to be 16.52 years. The mean age of 390 subjects (77.8%) who had no information about human papilloma virus was 15.75 years. It was found that only one of the subjects (0.9%) was vaccinated with HPV vaccine. When the subjects who did not wish to be vaccinated were asked for the reason, 40.9% stated that the reason was inadequate information, 26.4% stated that the reason was high cost, 16.4% stated that the reason was the fact that they did not consider themselves at risk and 16.4% stated that the reason was the fact that they were afraid of side effects. In our study, it was found that the adolescent girls who constituted our study group had insufficient information about HPV and HPV vaccine. Verbal, written and visual communication tools and internet should be used intensively and efficiently for the objective of introducing HPV vaccine and teaching the precautions related with prevention of cervix cancer in terms of public health. Primarily pediatrician and gynecologists and family physicians who give service for the adolescence age group should be supported to develop appropriate attitudes and behaviors related with HPV vaccine and infection.
The European Journal of Contraception and Reproductive Health Care, 2014
This study evaluated the clinical outcomes and safety of treating caesarean scar pregnancy (CSP) ... more This study evaluated the clinical outcomes and safety of treating caesarean scar pregnancy (CSP) by means of suction curettage followed when required by Foley tamponade, with or without methotrexate (MTX) therapy preceding the curettage. Twenty-five patients with CSP were identified between August 2008 and April 2012. The first team of doctors treated Group A patients (n = 11) with systemic MTX followed by dilatation and suction curettage whereas the second team of doctors carried out only a suction curettage on women of Group B (n = 14). If uncontrolled vaginal bleeding occurred in either group during or after the operation, a Foley catheter, guided by real time transabdominal ultrasound, was placed in the uterine cavity against the site where the CSP had been implanted. Clinical outcomes in the two groups - including mean estimated blood loss, major complication rate, and hospital length of stay - were comparable. Surgeons used Foley catheter balloons for tamponade in six of the 11 patients in Group A and in seven of the 14 patients in Group B. Treatment was successful in ten of 11 cases in group A and 13 of 14 cases in group B. Group B's mean duration of treatment (2.36 ± 0.49 days) was significantly shorter than that of Group A (14.45 ± 4.96 days; p < 0.001). Suction curettage, followed when needed by Foley catheter tamponade, is an effective treatment for CSP.
Journal of the Turkish German Gynecological Association, 2014
To evaluate the natural history of isolated muscular ventricular septal (m-VSD) defects during ge... more To evaluate the natural history of isolated muscular ventricular septal (m-VSD) defects during gestation and up to 1 year postnatally, as well as the association with chromosomal anomalies. Between August 2007 and July 2012, 76 fetuses with isolated m-VSDs represented the study population. The following variables were evaluated: site and size of the m-VSDs, presence of chromosomal anomalies, pregnancy outcome, and spontaneous closure rate from diagnosis up to 1 year postnatally. Of the 76 cases with m-VSD, 1 fetus died after birth and 31 cases were lost to follow-up after birth. Thus, a total of 44 fetuses reached their first year of postnatal life, and these cases were available for analysis. Three (6.8%) of 44 defects closed spontaneously in utero, 33 (75%) closed within 1 year, and 8 (18.2%) remained patent. Overall, spontaneous closure occurred more frequently in the apical defects, but no significant difference was found for spontaneous closure between the mid-muscular and apical defects (p>0.05). Also, 83.8% (36 of 44) of defects ≤3 mm closed during gestation or the first year of life. We infer that m-VSDs have a high spontaneous closure rate during the first year of life. Also, small m-VSDs frequently close spontaneously.
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