JMIRx Bio

An overlay journal for BioRxiv preprints with post-review manuscript marketplace (What is JMIRx?).

Editor-in-Chief:

Amy Schwartz, MSc, Ph.D., Scientific Editor at JMIR Publications, Ontario, Canada

JMIRx Bio is an innovative overlay journal to BioRxiv and JMIR Preprints (other preprint servers are invited to join). JMIRx peer-reviews preprints and publishes their revised "version of record" with peer-review reports across a broad range of biological sciences. We also accept existing reviews from Plan P accredited peer-review services such as PeerRef or PREreview Preprint Journal Clubs.

Unlike the majority of JMIR journals, papers published in this journal do not require a digital health focus. We publish all research that qualifies for preprinting on BioRxiv.

Conceived to address the urgent need to make highly relevant scientific information available as early as possible without losing the quality of the peer-reviewed process, this innovative new journal is the first in a new series of “superjournals”. Superjournals (a type of "overlay" journal) sit on top of preprint servers (JMIRx Bio serves BioRxiv and JMIR Preprints), offering peer-review and everything else a traditional scholarly journal does. Our goal is to rapidly peer review and publish a paper. All JMIRx Bio papers must have originated as a preprint.

All preprints accepted for curation in JMIRx Bio as "Version-of-Record" are rigorously peer-reviewed, copyedited and XML-tagged. Accepted papers are published along with the related Peer Review Reports and Author Responses to Peer Review Reports, providing an additional layer of transparency to the scholarly publishing process.

There is no Article Processing Fee directly paid by authors for this journal. JMIRx Bio is a diamond open access journal publishing under a PRC model and Plan-P compliant journal, which enables Plan P member universities/institutions and funders to support peer review of preprints and publishing in JMIRx Bio or partner journals. Under Plan P, the institution contributes $1000 towards peer-review (and publication of the peer-review reports), and the funder (if applicable) contributes $1000 for the publication/curation costs, in case the article is accepted. Individual PI-led labs, departments and universities can become institutional members, guaranteeing unlimited peer-review of preprints.

Introductory waivers. For a limited time only, authors who opt-in during submission to receive PREreview community peer review for their preprint or refer us to their department head/librarian/funder contact will receive a membership-waiver and may publish the preprint in JMIRx Bio at no cost to the author. To benefit from this simply refer us to your library, referral form provided here.

To "submit" (nominate a preprint for JMIRx), please use this form at https://bio.jmirx.org/landing.

For detailed instructions and other submission options see How to submit to a JMIRx journal

Recent Articles

#PREreview Live Review Report

Peer Review of “Exploring the Accuracy of Ab Initio Prediction Methods for Viral Pseudoknotted RNA Structures (Preprint)”

Authors' Responses to Peer-Reviews

Authors’ Response to Peer Reviews of “In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study”

Peer Reviews

Peer Review of “In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study”

Peer Reviews

Peer Review of “In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study”

#xSystems Biology

In-Silico Works Using an Improved Hovorka Equations Model and Clinical Works on the Control of Blood Glucose Levels in People With Type 1 Diabetes: Comparison Study

People with type 1 diabetes (T1D) depend on external insulin to regulate their blood glucose level (BGL) within the normoglycemic range between 4.0 to 7.0 mmol/L. Patients with T1D routinely conduct self-monitoring of blood glucose through finger pricks before insulin injections. An artificial pancreas is an innovative device that mimics the function of a healthy pancreas. Despite its recent advancement, the control algorithms used in an artificial pancreas are still lagging in delivering the proper insulin dosage to patients with T1D. Previous researchers attempted to improve the interrelation between parameters and variables in the original Hovorka equations model, later known as the improved Hovorka equations model; however, the improved equations model has not been tested in terms of its usability to regulate and control the BGL in a safe range for 2 or more people with T1D.

Peer Reviews

Peer Review of “Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study”

Authors' Responses to Peer-Reviews

Authors’ Response to Peer Reviews of “Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study”

Peer Reviews

Peer Review of “Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study”

#xCell Biology

Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study

The culture of immortal cell lines has become an indispensable tool in the field of modern biotechnology and has been used in the production of human and viral veterinary vaccines, therapeutic recombinant proteins, interferons, and monoclonal antibodies. Several approaches are used to immortalize cells in culture, such as transduction of cells with viral oncogenes, induced expression of telomerase reverse transcriptase, and spontaneous immortalization by serial passage of primary cell lines.