etoposid (Q418817)

(8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one ^Saesneg

inferred from SMILES ^Saesneg

1 ffynhonnell

inferred from SMILES ^Saesneg

rhan o'r canlynol

response to etoposide ^Saesneg

rôl y pwnc

reactant ^Saesneg

1 ffynhonnell

Gene Ontology release 2019-11-16 ^Saesneg

defnydd

cyffur meddygol

0 ffynonellau

adeiledd gemegol

Etoposide.svg
512 × 572; 14 KB

1 ffynhonnell

mewnforiwyd o

Wicipedia Almaeneg

image of molecular model or crystal lattice model ^Saesneg

Etoposide ball-and-stick.png
2,000 × 1,418; 295 KB

yn portreadu

ball-and-stick model ^Saesneg

0 ffynonellau

màs

588.184 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

(5S,5aS,8aS,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one ^Saesneg

17 Tachwedd 2016

stereoisomer of ^Saesneg

1 ffynhonnell

inferred from InChI ^Saesneg

fformwla gemegol

C₂₉H₃₂O₁₃

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

isomeric SMILES ^Saesneg

C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

Toposar ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

220347

14 Chwefror 2018

Etopophos ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

274342

14 Chwefror 2018

World Health Organisation international non-proprietary name ^Saesneg

etoposidum (Lladin)

1 ffynhonnell

Recommended INN: List 16 ^Saesneg

etopósido (Sbaeneg)

1 ffynhonnell

MedNet INN ^Saesneg

13 Mehefin 2024

etoposide (Saesneg)

1 ffynhonnell

Recommended INN: List 16 ^Saesneg

found in taxon ^Saesneg

Trichoderma cornu-damae ^Saesneg

1 ffynhonnell

Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom, Podostroma cornu-damae ^Saesneg

Aspergillus alliaceus ^Saesneg

1 ffynhonnell

Coculture of Two Developmental Stages of a Marine-Derived Aspergillus alliaceus Results in the Production of the Cytotoxic Bianthrone Allianthrone A. ^Saesneg

Linum flavum ^Saesneg

1 ffynhonnell

Isolation, Purification, and Cytotoxicity of 5-Methoxypodophyllotoxin, a Lignan from a Root Culture of Linum flavum ^Saesneg

Trichoderma gamsii ^Saesneg

1 ffynhonnell

Trichoderpyrone, a Unique Polyketide Hybrid with a Cyclopentenone-Pyrone Skeleton from the Plant Endophytic Fungus Trichoderma gamsii ^Saesneg

Aspergillus porosus ^Saesneg

1 ffynhonnell

Polyketides from Marine-Derived Aspergillus porosus: Challenges and Opportunities for Determining Absolute Configuration ^Saesneg

Aspergillus versicolor ^Saesneg

1 ffynhonnell

Avertoxins A-D, Prenyl Asteltoxin Derivatives from Aspergillus versicolor Y10, an Endophytic Fungus of Huperzia serrata. ^Saesneg

Gwylys

1 ffynhonnell

Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra. ^Saesneg

Flueggea suffruticosa ^Saesneg

1 ffynhonnell

Securinega Alkaloids from the Twigs of Securinega suffruticosa and Their Biological Activities ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

canser ar yr ymennydd

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

neoplasm troffoblastig

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

histiocytosis ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

neoplasm diniwed ar yr ysgyfaint

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

lewcemia myeloid aciwt

2 ffynonellau

NDF-RT ^Saesneg

13 Rhagfyr 2016

2 Hydref 2018

rhabdomyosarcoma ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

2 ffynonellau

NDF-RT ^Saesneg

13 Rhagfyr 2016

2 Hydref 2018

germ cell cancer ^Saesneg

1 ffynhonnell

2 Hydref 2018

B-cell lymphoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

lymffoma ddi-Hodgkin

1 ffynhonnell

2 Hydref 2018

testicular malignant germ cell cancer ^Saesneg

1 ffynhonnell

2 Hydref 2018

bone sarcoma ^Saesneg

1 ffynhonnell

2 Hydref 2018

neuroblastoma, susceptibility to ^Saesneg

1 ffynhonnell

2 Hydref 2018

diffuse large B-cell lymphoma ^Saesneg

1 ffynhonnell

dyddiad neu amser cychwyn

2 Hydref 2018

canser y ceilliau

10 Tachwedd 1983

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/6PLQ3CP4P3

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020457s013lbl.pdf

carsinoma cell bychain yr ysgyfaint

dyddiad neu amser cychwyn

17 Mai 1996

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/6PLQ3CP4P3

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020457s013lbl.pdf

significant drug interaction ^Saesneg

ciclosporin

side effect ^Saesneg

leukopenia ^Saesneg

1 ffynhonnell

manylrwydd y gosodiad

yn ôl pob tebyg

adweithia'n ffisegol gyda

A reference set of clinically relevant adverse drug-drug interactions ^Saesneg

DNA topoisomerase II alpha ^Saesneg

rôl y pwnc

enzyme inhibitor ^Saesneg

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

6815

arllwysiad mewnwythiennol

17 Awst 2016

dull gweini

0 ffynonellau

gweini genau

0 ffynonellau

legal status (medicine) ^Saesneg

boxed warning ^Saesneg

1 ffynhonnell

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

categori beichiogrwydd Awstralia D

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Saesneg)

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

categori beichiogrwydd Unol Daleithiau America D

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

rôl y pwnc

DNA polymerase inhibitors ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

topoisomerase inhibitor ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

phytogenic antineoplastic agents ^Saesneg

1 ffynhonnell

15 Mawrth 2018

topoisomerase II inhibitor ^Saesneg

1 ffynhonnell

15 Mawrth 2018

dyddiad neu amser cychwyn

1 Gorffennaf 1990

1 ffynhonnell

California Proposition 65 list of chemicals ^Saesneg

26 Chwefror 2020

https://oehha.ca.gov/chemicals/etoposide

carsinogen

1 ffynhonnell

California Proposition 65 list of chemicals ^Saesneg

26 Chwefror 2020

https://oehha.ca.gov/chemicals/etoposide

cyffur hanfodol

0 ffynonellau

categori Comin

Etoposide

0 ffynonellau

Identifiers

InChI

InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

33419-42-0

2 ffynonellau

UNII ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

9 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=33419-42-0

ChemSpider ID ^Saesneg

33510

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

33510

Etoposide (Saesneg)

17 Tachwedd 2016

PubChem CID ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

InChIKey ^Saesneg

ChEBI ID ^Saesneg

4911

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL44657

ETOPOSIDE (Saesneg)

17 Tachwedd 2016

International Chemical Identifier ^Saesneg

InChI

ChEMBL ID ^Saesneg

CHEMBL44657

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL44657

ETOPOSIDE (Saesneg)

17 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL4259

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

637000

1 ffynhonnell

splash10-004i-0190000000-ac64a57347a9295be5dc

UniChem ^Saesneg

MassBank accession ID ^Saesneg

MSBNK-Fiocruz-FIO00430

0 ffynonellau

MSBNK-Fiocruz-FIO00431

0 ffynonellau

MSBNK-Fiocruz-FIO00432

0 ffynonellau

MSBNK-Fiocruz-FIO00433

0 ffynonellau

MSBNK-Fiocruz-FIO00434

0 ffynonellau

MSBNK-Waters-WA002745

0 ffynonellau

MSBNK-Waters-WA002746

0 ffynonellau

MSBNK-Waters-WA002747

0 ffynonellau

MSBNK-Waters-WA002748

0 ffynonellau

MSBNK-Waters-WA002749

0 ffynonellau

MSBNK-Waters-WA002750

0 ffynonellau

MSBNK-Waters-WA002751

0 ffynonellau

SPLASH ^Saesneg

0 ffynonellau

splash10-004r-0590000000-e0e45774111103754c46

0 ffynonellau

splash10-002r-0980000000-ccf595459b4b1988d77a

0 ffynonellau

splash10-002r-0950000000-4d3313053107615d463a

0 ffynonellau

DSSTox substance ID ^Saesneg

DTXSID5023035

1 ffynhonnell

InChIKey ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID203035

0 ffynonellau

LiverTox ID ^Saesneg

EtoposideTeniposide

0 ffynonellau

NSC number ^Saesneg

141540

0 ffynonellau

757804

0 ffynonellau

EC number ^Saesneg

251-509-1

1 ffynhonnell

UNII ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

ECHA Substance Infocard ID ^Saesneg

100.046.812

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

27 Rhagfyr 2018

Etoposide (Saesneg)

CAS no.: 33419-42-0 (Saesneg)

Cod yr ATC

L01CB01

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

00773

dynodwr Llawlyfr Ffarmacoleg Ligand

Etoposide (Saesneg)

dyddiad cyhoeddi

17 Tachwedd 2015

World Health Organisation international non-proprietary name numeric ID ^Saesneg

3835

0 ffynonellau

6815

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

6815

D02.455.426.559.847.638.960.675.250

etoposide (Saesneg)

17 Tachwedd 2016

Etoposide

0 ffynonellau

MeSH concept ID ^Saesneg

M0007930

0 ffynonellau

Cod MeSH

0 ffynonellau

D04.615.638.960.675.250

0 ffynonellau

D09.408.348.275

0 ffynonellau

RxNorm ID ^Saesneg

4179

1 ffynhonnell

UNII ^Saesneg

etoposide (Saesneg)

Dynodwr Drugbank (Alberta)

17 Tachwedd 2016

DB00773

1 ffynhonnell

InChIKey ^Saesneg

dynodwr HMDB

HMDB0014911

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

UNII ^Saesneg

2 ffynonellau

UNII ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

InChIKey ^Saesneg

MedlinePlus drug identifier ^Saesneg

0 ffynonellau

intravenous injection ^Saesneg

0 ffynonellau

1 ffynhonnell

UNII ^Saesneg

etoposide (Saesneg)

17 Tachwedd 2016

Probes And Drugs ID ^Saesneg

PD003202

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

4911

etoposide (Saesneg)

19 Hydref 2016

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

4911

etoposide (Saesneg)

19 Hydref 2016

0 ffynonellau

CA PROP 65 ID ^Saesneg

etoposide

1 ffynhonnell

California Proposition 65 list of chemicals ^Saesneg

6 Ionawr 2020

https://oehha.ca.gov/chemicals/etoposide

DeCS ID ^Saesneg

5143

0 ffynonellau

electronic Essential Medicines List medicine ID ^Saesneg

0 ffynonellau

dynodwr Encyclopædia Britannica Online

science/etoposide

enwyd fel

etoposide

0 ffynonellau

dynodwr Freebase

/m/077tsy

1 ffynhonnell

dynodwr Microsoft Academic

Freebase Data Dumps ^Saesneg

dyddiad cyhoeddi

28 Hydref 2013

2778119113

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

4LB9

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

4LB9

4LB9 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

3QX3

3QX3 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

5CDP

5CDP (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

5CDN

5CDN (Saesneg)

19 Hydref 2016

Römpp online ID ^Saesneg

1 ffynhonnell

UMLS CUI ^Saesneg

1 ffynhonnell

UNII ^Saesneg

etoposide (Saesneg)