epidermal growth factor (Q424374)

Pro-epidermal growth factor

1 reference

Growth factor receptor cysteine-rich domain superfamily

1 reference

EGF-like calcium-binding domain, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

LDLR class B repeat, protein family

1 reference

EGF-like calcium-binding, conserved site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

transmembrane receptor protein tyrosine kinase activator activity

1 reference

8 April 2019

Nerve growth factor regulation of m4 muscarinic receptor mRNA stability but not gene transcription requires mitogen-activated protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

epidermal growth factor receptor binding

Nerve growth factor regulation of m4 muscarinic receptor mRNA stability but not gene transcription requires mitogen-activated protein kinase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

Wnt-protein binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

protein binding

9 references

8 April 2019

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Ligand-induced structural transitions in ErbB receptor extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Secreted and O-GlcNAcylated MIF binds to the human EGF receptor and inhibits its activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

growth factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

3 references

8 April 2019

8 April 2019

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

Wnt-activated receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

1 reference

1 January 2018

integral component of membrane

cell component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

receptor complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

lysosomal membrane

1 reference

31 October 2017

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

extracellular exosome

4 references

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

31 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

31 October 2017

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

platelet alpha granule lumen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

clathrin-coated vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

plasma membrane

Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

lysosomal membrane

1 reference

8 April 2019

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

extracellular exosome

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

negative regulation of epidermal growth factor receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

positive regulation of MAP kinase activity

1 reference

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

regulation of protein localization to cell surface

1 reference

8 April 2019

Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

ERK1 and ERK2 cascade

1 reference

8 April 2019

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

platelet degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

regulation of calcium ion import

1 reference

8 April 2019

Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

mammary gland alveolus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

DNA replication

1 reference

31 October 2017

Expression of Q227L-galphas in MCF-7 human breast cancer cells inhibits tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

negative regulation of secretion

1 reference

8 April 2019

ErbB2 and ErbB3 receptors mediate inhibition of calcium-dependent chloride secretion in colonic epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of hyaluronan biosynthetic process

1 reference

8 April 2019

Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of peptidyl-threonine phosphorylation

1 reference

8 April 2019

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

angiogenesis

1 reference

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

Wnt signaling pathway involved in dorsal/ventral axis specification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

1 reference

31 October 2017

positive regulation of cell population proliferation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of cerebellar granule cell precursor proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

canonical Wnt signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

negative regulation of cholesterol efflux

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of phosphorylation

1 reference

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of mitotic nuclear division

1 reference

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

branching morphogenesis of an epithelial tube

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

regulation of peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

ERBB2 signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

phosphatidylinositol phosphate biosynthetic process

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

positive regulation of protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

activation of transmembrane receptor protein tyrosine kinase activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

regulation of cell motility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

positive regulation of receptor internalization

1 reference

8 April 2019

Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of epidermal growth factor-activated receptor activity

Nerve growth factor regulation of m4 muscarinic receptor mRNA stability but not gene transcription requires mitogen-activated protein kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

IMP

8 April 2019

Epidermal growth factor's activation of Ras is inhibited by four cardiac hormones

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

8 April 2019

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

membrane organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

negative regulation of ERBB signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

embryonic retina morphogenesis in camera-type eye

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01133&geneProductId=UniProtKB:P01133

1 reference

31 October 2017

positive regulation of gene expression

1 reference

8 April 2019

Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of cell migration

1 reference

8 April 2019

Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of protein kinase B signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

negative regulation of Notch signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

1 reference

8 April 2019

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Epidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

positive regulation of protein localization to early endosome

1 reference

8 April 2019

The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01133

physically interacts with

epidermal growth factor receptor

0 references

Gene Atlas image

PBB GE EGF 206254 at fs.png
732 × 530; 10 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P01133

1 reference

EGF-type aspartate/asparagine hydroxylation site

Identifiers.org

has part(s)

1 reference

EGF-like calcium-binding, conserved site

1 reference

EGF-like, conserved site

1 reference

EGF-like calcium-binding domain

1 reference

EGF-like domain

1 reference

LDLR class B repeat

1 reference

imported from Wikimedia project

Commons category

Epidermal growth factor, EGF

1 reference

English Wikipedia

Identifiers

MeSH descriptor ID

D004815

subject named as

Epidermal Growth Factor

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1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023