Bruton's tyrosine kinase (Q423572)

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mammalian protein found in Homo sapiens
  • ATK
  • Agammaglobulinaemia Tyrosine Kinase
  • tyrosine-protein kinase BTK isoform (lacking exon 13 to 17)
  • tyrosine-protein kinase BTK
  • B-cell progenitor kinase
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • Agammaglobulinemia tyrosine kinase
  • Bruton agammaglobulinemia tyrosine kinase
  • agammaglobulinaemia tyrosine kinase
  • BTK
  • BPK
  • tyrosine-protein kinase BTK isoform (lacking exon 14)
  • truncated Bruton agammaglobulinemia tyrosine kinase
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Language Label Description Also known as
English
Bruton's tyrosine kinase
mammalian protein found in Homo sapiens
  • ATK
  • Agammaglobulinaemia Tyrosine Kinase
  • tyrosine-protein kinase BTK isoform (lacking exon 13 to 17)
  • tyrosine-protein kinase BTK
  • B-cell progenitor kinase
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • Agammaglobulinemia tyrosine kinase
  • Bruton agammaglobulinemia tyrosine kinase
  • agammaglobulinaemia tyrosine kinase
  • BTK
  • BPK
  • tyrosine-protein kinase BTK isoform (lacking exon 14)
  • truncated Bruton agammaglobulinemia tyrosine kinase

Statements

part of
molecular function
protein binding
determination method or standard
IPI
12 references
retrieved
8 April 2019
stated in
Regulated association of protein kinase B/Akt with breast tumor kinase
GOA
curator
UniProt
UniProt protein ID
Q06187
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Btk-dependent regulation of phosphoinositide synthesis
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
retrieved
8 April 2019
stated in
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q06187
determination method or standard
IPI
cell component
biological process
Gene Atlas image
PBB GE BTK 205504 at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D000077329
subject named as
Agammaglobulinaemia Tyrosine Kinase
0 references
PDB structure ID
 
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