Mutational analysis of the human immunodeficiency virus type 1 Vpu transmembrane domain that promotes the enhanced release of virus-like particles from the plasma membrane of mammalian cells. (Q39642301)

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scientific article published on February 1998

Language	Label	Description	Also known as
English	Mutational analysis of the human immunodeficiency virus type 1 Vpu transmembrane domain that promotes the enhanced release of virus-like particles from the plasma membrane of mammalian cells.	scientific article published on February 1998

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scholarly article

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8 November 2019

Mutational analysis of the human immunodeficiency virus type 1 Vpu transmembrane domain that promotes the enhanced release of virus-like particles from the plasma membrane of mammalian cells (English)

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Europe PubMed Central

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8 November 2019

transmembrane protein

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mutational analysis

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based on heuristic

inferred from title

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M Paul

1

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8 November 2019

S Mazumder

2

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8 November 2019

N Raja

3

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8 November 2019

M A Jabbar

4

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8 November 2019

language of work or name

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publication date

1 February 1998

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8 November 2019

Journal of Virology

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8 November 2019

72

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8 November 2019

2

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8 November 2019

1270-1279

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8 November 2019

Putative alpha-helical structures in the human immunodeficiency virus type 1 Vpu protein and CD4 are involved in binding and degradation of the CD4 molecule

1 reference

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14 September 2017

The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer.

1 reference

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14 September 2017

Ion channels as enzymes: analogy or homology?

1 reference

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14 September 2017

The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses.

1 reference

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14 September 2017

The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels

1 reference

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14 September 2017

CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nef.

1 reference

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14 September 2017

The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus

1 reference

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14 September 2017

The human immunodeficiency virus type 1 Vpu protein tethered to the CD4 extracellular domain is localized to the plasma membrane and is biologically active in the secretory pathway of mammalian cells: implications for the mechanisms of Vpu function

1 reference

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14 September 2017

Human immunodeficiency virus type 2 glycoprotein enhancement of particle budding: role of the cytoplasmic domain

1 reference

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14 September 2017

The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Functional analysis of the phosphorylation sites on the human immunodeficiency virus type 1 Vpu protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Folding and assembly of viral membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Mutations in the N-terminal region of human immunodeficiency virus type 1 matrix protein block intracellular transport of the Gag precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Human immunodeficiency virus type 1 Vpu protein induces degradation of chimeric envelope glycoproteins bearing the cytoplasmic and anchor domains of CD4: role of the cytoplasmic domain in Vpu-induced degradation in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Sequences present in the cytoplasmic domain of CD4 are necessary and sufficient to confer sensitivity to the human immunodeficiency virus type 1 Vpu protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Characterization of human immunodeficiency virus type 1 Pr55gag membrane association in a cell-free system: requirement for a C-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Influenza A virus M2 ion channel protein: a structure-function analysis

1 reference

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14 September 2017

Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Use of a hybrid vaccinia virus-T7 RNA polymerase system for expression of target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Identification of a protein encoded by the vpu gene of HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1 reference

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14 September 2017

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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14 September 2017

Functional role of human immunodeficiency virus type 1 vpu.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124605

14 September 2017

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

1 reference

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14 September 2017

Intracellular interaction of human immunodeficiency virus type 1 (ARV-2) envelope glycoprotein gp160 with CD4 blocks the movement and maturation of CD4 to the plasma membrane

1 reference

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14 September 2017

CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor

1 reference

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14 September 2017

Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs

1 reference

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14 September 2017

Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments

1 reference

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Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

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Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein

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Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes

1 reference

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14 September 2017

Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export

1 reference

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An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1

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14 September 2017

Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4

1 reference

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Influenza virus M2 protein has ion channel activity

1 reference

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14 September 2017

Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function

1 reference

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A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum

1 reference

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The role of Nef in the replication cycle of the human and simian immunodeficiency viruses

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14 September 2017

The Human Immunodeficiency Virus Type 1 Vpu Protein: Roles in Virus Release and CD4 Downregulation

1 reference

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HIV accessory proteins: leading roles for the supporting cast.

1 reference

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Human immunodeficiency virus-like, nonreplicating, gag-env particles assemble in a recombinant vaccinia virus expression system

1 reference

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14 September 2017

HIV-1 particle release mediated by Vpu is distinct from that mediated by p6.

1 reference

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Do Vpu and Vpr of human immunodeficiency virus type 1 and NB of influenza B virus have ion channel activities in the viral life cycles?

1 reference

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25 September 2017

Regulation of HIV-1 gag protein subcellular targeting by protein kinase C.

1 reference

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25 September 2017

Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity

1 reference

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25 September 2017

The effect of vpu on HIV-1-induced syncytia formation.

1 reference

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15 June 2018

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

1 reference

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1 reference

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/9445027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of heterologous protein degradation by the Vpu protein of HIV-1 requires the transmembrane and cytoplasmic domains of CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly and morphology of HIV: potential effect of structure on viral function

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inferred from PubMed ID database lookup

Form, function, and use of retroviral gag proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9445027

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based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9445027%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9445027%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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