O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication (Q35583518)

9 August 2017

title

O4-Methyl, -ethyl, or -isopropyl substituents on thymidine in poly(dA-dT) all lead to transitions upon replication (English)

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9 August 2017

B Singer

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9 August 2017

S J Spengler

series ordinal

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9 August 2017

H Fraenkel-Conrat

series ordinal

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9 August 2017

J T Kuśmierek

series ordinal

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9 August 2017

language of work or name

English

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publication date

1 January 1986

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

28-32

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Alkylation of nucleic acids by N-nitrosodi-n-propyl-amine: evidence that carbonium ions are not significantly involved

9 August 2017

cites work

1 reference

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Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats

12 July 2018

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The incorporation of O6-methyldeoxyguanosine and O4-methyldeoxythymidine monophosphates into DNA by DNA polymerases I and alpha

12 July 2018

1 reference

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Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

12 July 2018

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Reaction of 1-n-propyl-1-nitrosourea with DNA in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322784

O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine

12 July 2018

1 reference

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Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322784

Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis

12 July 2018

1 reference

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Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations.

12 July 2018

1 reference

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Fidelity of DNA synthesis

12 July 2018

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Assessment of mutagenic efficiency of two carcinogen-modified nucleosides, 1,N6-ethenodeoxyadenosine and O4-methyldeoxythymidine, using polymerases of varying fidelity

12 July 2018

1 reference

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Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues

12 July 2018

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[Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

12 July 2018

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Activated proto-onc genes: sufficient or necessary for cancer?

12 July 2018

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Evidence for a major premutagenic ethyldeoxythymidine-DNA adduct in an in vivo system: N-nitroso-N-ethylurea-treated Salmonella typhimurium

12 July 2018

1 reference

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Reaction of diazoalkanes with 1-substituted 2, 4-dioxopyrimidines. Formation of O2, N-3 and O4-alkyl products

12 July 2018

1 reference

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All oxygens in nucleic acids react with carcinogenic ethylating agents

12 July 2018

1 reference

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Oxygens in DNA are main targets for ethylnitrosourea in normal and xeroderma pigmentosum fibroblasts and fetal rat brain cells

12 July 2018

1 reference

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Base pairing structure in the poly d(G-T) double helix: wobble base pairs

12 July 2018

1 reference

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Preparation and template activities of polynucleotides containing O2- and O4-alkyluridine

12 July 2018

1 reference

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Synthesis and coding properties of dinucleoside diphosphates containing alkyl pyrimidines which are formed by the action of carcinogens on nucleic acids

12 July 2018

1 reference

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O2- and O4-Alkyl pyrimidine nucleosides: stability of the glycosyl bond and of the alkyl group as a function of pH

12 July 2018

1 reference

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The effects of methylated thymidines upon cultures of V79 cells and the mechanism of incorporation of O4-methylthymidine into their DNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322784

The incorporation of O4-methylthymidine into V79A cell DNA when present in the cell culture medium

26 September 2018

1 reference

12 December 2020

In vitro reaction of N-n-butyl-N-nitrosourea and n-butyl methanesulphonate with guanine and thymine bases of DNA

1 reference

12 December 2020

Genetically determined susceptibility of Fischer 344 rats to propylnitrosourea-induced thymic lymphomas

1 reference

12 December 2020

Differential repair of O4-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens

1 reference

12 December 2020

CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5-TRIPHOSPHATES

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12 December 2020

Identifiers

DOI

10.1073/PNAS.83.1.28

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9 August 2017

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9 August 2017

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