Apoptosis: controlled demolition at the cellular level (Q29620114)

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29 December 2019

review article

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title

Apoptosis: controlled demolition at the cellular level (English)

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30 April 2017

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29 December 2019

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29 December 2019

Rebecca C Taylor

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29 December 2019

Sean P Cullen

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29 December 2019

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30 April 2017

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1 March 2008

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Nature Reviews Molecular Cell Biology

29 December 2019

published in

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29 December 2019

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30 April 2017

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29 December 2019

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29 December 2019

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

29 December 2019

cites work

1 reference

Cell death: the significance of apoptosis

31 March 2020

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

31 March 2020

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Caspase-activation pathways in apoptosis and immunity

31 March 2020

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Corpse clearance defines the meaning of cell death

31 March 2020

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Morphological aspects of glucocorticoid-induced cell death in human lymphoblastoid cells

31 March 2020

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HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis

31 March 2020

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Association of mammalian cell death with a specific endonucleolytic degradation of DNA

31 March 2020

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

31 March 2020

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Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis

31 March 2020

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The CASBAH: a searchable database of caspase substrates

31 March 2020

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Natural adjuvants: endogenous activators of dendritic cells

31 March 2020

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Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses

31 March 2020

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Molecular identification of a danger signal that alerts the immune system to dying cells

31 March 2020

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Alarmins: chemotactic activators of immune responses

31 March 2020

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

31 March 2020

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Cooperation of Toll-like receptor signals in innate immune defence

31 March 2020

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The danger model: a renewed sense of self

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

31 March 2020

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Properties of the caspases

31 March 2020

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Pro-caspase-3 is a major physiologic target of caspase-8.

31 March 2020

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The mitochondrial apoptosome: a killer unleashed by the cytochrome seas

31 March 2020

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Functional consequences of caspase activation in cardiac myocytes

31 March 2020

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The Fas-induced apoptosis analyzed by high throughput proteome analysis

31 March 2020

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Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

31 March 2020

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Shotgun proteome analysis of protein cleavage in apoptotic cells

31 March 2020

1 reference

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

31 March 2020

1 reference

Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis

31 March 2020

1 reference

The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics

31 March 2020

1 reference

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

31 March 2020

1 reference

Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility.

31 March 2020

1 reference

Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action

31 March 2020

1 reference

Apoptosis generates stable fragments of human type I keratins

31 March 2020

1 reference

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

31 March 2020

1 reference

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

31 March 2020

1 reference

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

31 March 2020

1 reference

An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism

31 March 2020

1 reference

Lamin proteolysis facilitates nuclear events during apoptosis

31 March 2020

1 reference

Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration

31 March 2020

1 reference

A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation

31 March 2020

1 reference

Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis

31 March 2020

1 reference

The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells

31 March 2020

1 reference

Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.

31 March 2020

1 reference

Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin.

31 March 2020

1 reference

Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins.

31 March 2020

1 reference

Cleavage and shedding of E-cadherin after induction of apoptosis

31 March 2020

1 reference

The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes

31 March 2020

1 reference

The fate of desmosomal proteins in apoptotic cells

31 March 2020

1 reference

Selective cleavage of 28S rRNA variable regions V3 and V13 in myeloid leukemia cell apoptosis.

31 March 2020

1 reference

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

31 March 2020

1 reference

Cell nucleus and DNA fragmentation are not required for apoptosis

31 March 2020

1 reference

Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation

31 March 2020

1 reference

Features of systemic lupus erythematosus in Dnase1-deficient mice

31 March 2020

1 reference

CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis.

31 March 2020

1 reference

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

31 March 2020

1 reference

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

31 March 2020

1 reference

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

31 March 2020

1 reference

Trashing the genome: the role of nucleases during apoptosis

31 March 2020

1 reference

Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

31 March 2020

1 reference

Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation

31 March 2020

1 reference

Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae

31 March 2020

1 reference

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

31 March 2020

1 reference

A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis

31 March 2020

1 reference

Caspase-mediated cleavage of syntaxin 5 and giantin accompanies inhibition of secretory traffic during apoptosis

31 March 2020

1 reference

Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells.

31 March 2020

1 reference

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

31 March 2020

1 reference

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

31 March 2020

1 reference

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

31 March 2020

1 reference

Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics

31 March 2020

1 reference

Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation

31 March 2020

1 reference

Role of Bax and Bak in mitochondrial morphogenesis

31 March 2020

1 reference

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

31 March 2020

1 reference

Caspase activation inhibits proteasome function during apoptosis

31 March 2020

1 reference

Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.

31 March 2020

1 reference

Immunosuppressive effects of apoptotic cells

31 March 2020

1 reference

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

31 March 2020

1 reference

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

31 March 2020

1 reference

The induction of tolerance by dendritic cells that have captured apoptotic cells

31 March 2020

1 reference

Rho kinase regulates fragmentation and phagocytosis of apoptotic cells

31 March 2020

1 reference

Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

31 March 2020

1 reference

Two distinct cytokines released from a human aminoacyl-tRNA synthetase

31 March 2020

1 reference

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

31 March 2020

1 reference

Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity

31 March 2020

1 reference

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

31 March 2020

1 reference

A receptor for phosphatidylserine-specific clearance of apoptotic cells

31 March 2020

1 reference

The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells

31 March 2020

1 reference

Identification of a factor that links apoptotic cells to phagocytes

31 March 2020

1 reference

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

31 March 2020

1 reference

Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition

31 March 2020

1 reference

Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells

31 March 2020

1 reference

Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro

31 March 2020

1 reference

Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

31 March 2020

1 reference

Annexin I Is an Endogenous Ligand that Mediates Apoptotic Cell Engulfment

31 March 2020

1 reference

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

31 March 2020

1 reference

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis

31 March 2020

1 reference

Enhancement of macrophage phagocytosis upon iC3b deposition on apoptotic cells

31 March 2020

1 reference

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31 March 2020

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30 April 2017

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29 December 2019

1002866063

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30 April 2017

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