Lysine acetyltransferase 2A (Q21110334)

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mammalian protein found in Homo sapiens
  • histone succinyltransferase KAT2A
  • hsGCN5
  • K(lysine) acetyltransferase 2A
  • KAT2A
  • general control of amino acid synthesis protein 5-like 2
  • histone acetyltransferase KAT2A
  • STAF97
  • histone glutaryltransferase KAT2A
  • histone acetyltransferase GCN5
  • General control of amino acid synthesis, yeast, homolog-like 2
  • GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
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Language Label Description Also known as
English
Lysine acetyltransferase 2A
mammalian protein found in Homo sapiens
  • histone succinyltransferase KAT2A
  • hsGCN5
  • K(lysine) acetyltransferase 2A
  • KAT2A
  • general control of amino acid synthesis protein 5-like 2
  • histone acetyltransferase KAT2A
  • STAF97
  • histone glutaryltransferase KAT2A
  • histone acetyltransferase GCN5
  • General control of amino acid synthesis, yeast, homolog-like 2
  • GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2

Statements

molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
8 April 2019
stated in
Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
Regulation of DNA methyltransferase 1 transcription in BRCA1-mutated breast cancer: a novel crosstalk between E2F1 motif hypermethylation and loss of histone H3 lysine 9 acetylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
And-1 is required for the stability of histone acetyltransferase Gcn5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
retrieved
8 April 2019
stated in
Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IPI
histone acetyltransferase activity
determination method or standard
IEA
IDA
TAS
7 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
cell component
nucleus
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
biological process
histone H3 acetylation
determination method or standard
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IEA
retrieved
8 April 2019
stated in
Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
GOA
curator
UniProt
UniProt protein ID
Q92830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA
retrieved
8 April 2019
stated in
Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92830
determination method or standard
IDA

Identifiers

 
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