Arrestin beta 2 (Q21109248)

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mammalian protein found in Homo sapiens
  • Arrestin beta-2
  • non-visual arrestin-3
  • arrestin 3
  • ARRB2
  • beta-arrestin-2
Language Label Description Also known as
English
Arrestin beta 2
mammalian protein found in Homo sapiens
  • Arrestin beta-2
  • non-visual arrestin-3
  • arrestin 3
  • ARRB2
  • beta-arrestin-2

Statements

molecular function
protein binding
determination method
IPI
25 references
retrieved
9 May 2019
stated in
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Novel function of beta-arrestin2 in the nucleus of mature spermatozoa
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptor
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Ubiquitination of CXCR7 controls receptor trafficking
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Carboxy-terminus of CXCR7 regulates receptor localization and function
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Global landscape of HIV-human protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
A scanning peptide array approach uncovers association sites within the JNK/beta arrestin signalling complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
β-arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Regulation of amygdalar PKA by beta-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Functional specialization of beta-arrestin interactions revealed by proteomic analysis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
retrieved
9 May 2019
stated in
Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IPI
cell component
cytoplasm
determination method
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IEA
retrieved
8 April 2019
stated in
beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
8 April 2019
stated in
Novel function of beta-arrestin2 in the nucleus of mature spermatozoa
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
8 April 2019
stated in
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
8 April 2019
stated in
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
8 April 2019
stated in
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
cytoplasm
determination method
IBA
IDA
IEA
8 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IEA
retrieved
9 May 2019
stated in
beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
9 May 2019
stated in
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
9 May 2019
stated in
Novel function of beta-arrestin2 in the nucleus of mature spermatozoa
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
9 May 2019
stated in
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR
GOA
curator
UniProt
UniProt protein ID
P32121
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
9 May 2019
stated in
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32121
determination method
IBA
biological process

Identifiers

MeSH descriptor ID
D000071560
subject named as
beta-Arrestin 2
0 references
 
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