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Trichuris Trichuria

The document provides an overview of Trichuris trichiura, an intestinal nematode causing whipworm infection (trichuriasis) in humans. It details the life cycle, morphology, pathogenesis, clinical findings, lab diagnosis, treatment, and prevention methods associated with the parasite. Key points include transmission via the feco-oral route and the use of mebendazole as the drug of choice for treatment.

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ayesha fazal
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38 views20 pages

Trichuris Trichuria

The document provides an overview of Trichuris trichiura, an intestinal nematode causing whipworm infection (trichuriasis) in humans. It details the life cycle, morphology, pathogenesis, clinical findings, lab diagnosis, treatment, and prevention methods associated with the parasite. Key points include transmission via the feco-oral route and the use of mebendazole as the drug of choice for treatment.

Uploaded by

ayesha fazal
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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CLINICAL

PARASITOLOG
Y

TRICHURIS
TRICHIURA
PRESENTED BY: GROUP 3 MLT 5 T H E (HUSNAIN
KHALID)
PRESENTED TO: MAM ANUM TANVEER

• Husnain Khalid 224359 • Nimra Asad 224350


• Muhammad Atif 224362 • Ambreen Asghar 224369
• Muhammad Tauheed 224372 • Fiza Nawaz 224374
• Usama Rehman 224373 • Sana Iram 224378
• Muhammad Shoukat • Ayesha Fazal 224379
224385
• Amina noor 224391
• Rajab Ali
224388
CONTENT

• Introduction • Pathogenesis
• Stages in life cycle • Clinical finding
• Morphology • Lab diagnosis
• Transmission • Treatment
• Life cycle • Prevention
INTRODUCTION

• It is an intestinal Nematode
• Cause Whipworm infection ( Trichuriasis )
• Host … … Human
• Habitat… … soil
STAGES IN LIFE CYCLE

• Three main stage in life


cycle
1: Egg
2: Larva
3: Adult worm
MORPHOLOGY

EGG:
• SHAPE: Barrel or lemon shape
with a plug at each end , thick
shelled.
• SIZE: 50 – 55 micro meter
• COLOR: Brown, ( pink on H&E
stain )
• INFECTIVE STAGE:
Embryonated egg
• DIAGNOSTIC STAGE:
Unembryonated egg
MORPHOLOGY

ADULT WORM:
STRUCTURE:
• Whip like appearance
• Narrow anterior esophageal end
• Shorter and thicker posterior
end
• Attach to host through the
slender anterior
• Cuticle layer
MORPHOLOGY

• Feed on tissue secretion, not


blood
• Trichuris have both male and
female gender
• Females are larger than male
POSTERIOR END: Female
(round), Male (coiled)
SIZE: Male (30-45) , Female
(35-50)
TRANSMISSION

• By feco-oral route ( food and water


contaminated with human feces)
• By soil contact
LIFE CYCLE IN HUMAN

• Infection acquired by ingesting worm egg ( in food and


water contaminated with human feces)
• Egg hatch in small intestine
• Larva differentiate into immature adult
• Migrate to colon and mature
• Male and female adult live in colon
• Where matting occur
• Release thousand of eggs per day (3,000 to 20,000)
• Eggs passed in feces
LIFE CYCLE IN EXTERNAL
ENVIRONMENT

• Eggs deposit in warm and moist soil


• Form embryos
• Eggs become infective in 15-30 days
• Embryonated egg ingested by human and life
cycle is complete.
LIFE CYCLE
PATHOGENESIS

• Hairlike anterior end burrows into small


intestine mucosa
• Posterior end burrows into lumen
• Cause rectal prolapse
• increased peristalsis
• prolapsed mucosa
CLINICAL FINDINGS
(SYMPTOMS)

• Mostly asymptomatic
• Diarrhea (bloody)
• Rectal prolapse
• Nausea
• Anemia (no significant
as in hookworms
infection)
LAB DIAGNOSIS

SAMPLE:
• Feces
MICROSCOPY
• Eggs ( number and
shape)
• Having pink color on H&E
stain
TREATMENT

• Mebendazole drug of choice


PREVENTION

• Proper disposal of human feces


• Good hand & food hygiene
• Avoid walking bare foot

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