PHYSICAL &
CHEMICAL INJURIES
OF ORAL CAVITY
Dr. Diana Prem,
VMSDC, Salem.
PHYSICAL INJURIES OF ORAL CAVITY
(A) PHYSICAL INJURIES OF TEETH
1. BRUXISM
Also known as NIGHT-GRINDING or BRUXOMANIA
“Habitual grinding or clenching of the teeth either during sleep
or as an unconscious habit during walking hours”
Incidence - 5% & 20%
ETIOLOGY
(i) Local factors – Malocclusion
(ii) Systemic factors - Nutritional deficiency
- GIT disturbances
- Endocrinal disturbances
- Allergy
- Hereditary
(iii) Psychological factors - Anxiety
- Stress
- Emotional Tension
- Fear
- Rage
- Rejection
(iv) Occupations - Athletes
- Watch Makers
- Other persons associated with
precise work
- Voluntary Bruxism seen in
persons having habit of chew gum, tobacco,
toothpicks, pencils etc
CLINICAL FEATURES
History of clenching during sleep or walking hours is given by patient
The symptomatic effects of this habit have been reviewed by GLAROS & RAO,
who divide them into 6 major categories:
(a) Effects on the dentition - severe attrition at occlusal & proximal surfaces
- loosening & drifting of teeth
(b) Effects on the periodontium- gingival recession
(c) Effects on the masticatory muscles - fatigue of muscles
(d) Effects on TMJ
(e) Head pain
(f) Psychological & behavioral effects
TREATMENT
Removable splint should be worn at night
Correction of underlying causes should be done
2. FRACTURES OF TEETH
CAUSES
Traumatic episodes
It occurs frequently after endodontic treatment due
to brittle nature of non vital tooth
CLINICAL FEATURES
Mostly seen in children & maxillary teeth are
affected mostly
Class-1 - Simple fracture of the crown, involving
little or no dentin
Class-2 - Extensive fracture of the crown, involving
considerable dentin but not the dental pulp
Class-3 - Extensive fracture of the crown, involving
considerable dentin & exposing the dental
pulp
Class-4 - The traumatized tooth becomes non
vital, with or without loss of crown structure
Class-5 - Teeth lost as a result of trauma
Class-6 - Fracture of the root, with or without
loss of crown structure
Class-7 - Displacement of a tooth, without
fracture of crown or root
Class-8 - Fracture of the ‘crown en masse’ &
its replacement
Class-9 - Traumatic injuries to deciduous teeth
TOOTH FRACTURE
HISTOLOGICAL FEATURES
Histological features during healing are similar to that of bony fractures
Clot is organized with deposit of cementum & bone, later restoration & remodeling at
ends of fragments occurs
TREATMENT
If enamel is fractured - Restoration of missing tooth structure is done
If dentin is involved - Placement of sedative base (zinc oxide eugenol) is done at
fractured dentin & tooth is restored
If pulp is involved - Pulp capping
- Pulpotomy (coronal pulp removal)
- Pulpectomy
3. INJURIES TO THE SUPPORTING STRUCTURES
OF THE TOOTH
CONCUSSION - produce by injury which is not strong
enough to cause serious, visible damage to the tooth & the
periodontal structures
Characteristic feature- increased sensitivity of tooth to
percussion
Treatment - selective grinding of tooth to eliminate
occlusal forces
SUBLUXATION
- abnormal loosening of tooth without displacement due to
sudden trauma
- Tooth is mobile on palpation & sensitive to percussion &
occlusal forces
- tooth becomes nonvital due to severance of apical blood
supply
AVULSION - dislocation of the tooth from its socket due to
traumatic injury - partial or total
- Partial includes-intrusion, extrusion or facial, lingual or palatal or
lateral displacement.
- mainly accompanied by fracture of alveolar bone
4. TOOTH ANKYLOSIS
Fusion of tooth with bone
Occur mainly after any traumatic episode (occlusal trauma) or
periapiucal inflammatory processes or after RCT
CLINICAL FEATURES
Tooth shows lack of mobility
There may be evidence of pulpal ds.
Percussion over tooth gives characteristic solid sound
Deciduous tooth if affected becomes submerged b/c of eruption of
adjacent permanent teeth & growth of dental arch
RADIOGRAPHIC FEATURES
Blending of bone with tooth root is in radiograph
HISTOLOGICAL FEATURES
Area of root resorption is found, which have been repaired by bony tissues or
cementum
TREATMENT AND PROGNOSIS
There is no treatment for ankylosis
Good prognosis
Unless removed for some other reason, should serve well indefinitely
(B) PHYSICAL INJURIES OF BONE
1. FRACTURES OF JAW
Commonly due to automobile, industrial & sports accidents
& fight
Easily occur in bones which are already weakened by
developmental & systemic disorders
May be - Simple - bone is broken completely - overlying
structure are intact & not exposed to exterior
-Greenstick - common in children - characterized by break
of bone in on side & bend on the other side
- Compound - external wound in associated with the break
- e.g road traffic accidents
- comminuted - bone is crushed - may or may not be
exposed to exterior.
o Mandible is more prone for fractures
a) FRACTURES OF MAXILLA
- More serious
- In Road traffic accidents, blow, fall & industrial
accidents
- Extent of fracture is determined by - Direction , force
& location
*CLASSIFICATION
1. Le Fort-I / Horizontal Fracture / Floating Fracture
- separation of body of maxilla from base of skull
below the level of zygomatic process
2. Le Fort-II / Pyramidal Fracture
- vertical fractures through the facial aspects of
maxilla & extend upward to nasal & ethmoid
bones & usually extend from maxillary sinus
3. Le Fort III / Transverse Fracture
- high level fracture that extends
across the orbits through the base of the nose &
ethmoid
region to the zygomatic arch
- bony orbit is fractured & the lateral
rim is separated at the zygomaticofrontal suture
- zygomatic arch is fractured
Common Features
- Displacement, anterior open bite, swollen
face, reddish eye due to subcojuntival
hemorrhage & nasal hemorrhage
- If skull is involved - unconsciousness,
cerebrospinal fluid rhinorrhea
b) FRACTURES OF MANDIBLE
- mostly involve angle of mandible followed by
condyle, molar region,mental region & symphosis
- displacement of mandible depends on direction of the
line of fracture, muscle pull & direction of force
Clinical Features of mandibular fracture
Pain during movement
Occlusal derangement
Abnormal mobility
Gingival lacerations
Crepitus on movement
Trismus
Loss of sensation of involved side
Ecchymosis
Treatment
Immobilization of fractured bone
Complications
Nonunion
Malunion
Fibrous union
2. TRAUMATIC CYST
(SOLITARY CONE CYST, HEMORRHAGIC CYST, EXTRAVASATION CYST,
UNICAMERAL BONE CYST, SIMPLE BONE CYST, IDIOPATHIC BONE
CAVITY)
Is a pseudo cyst (lack epithelial lining) & an uncommon
lesion comprises about 1% of all jaw cyst
Occur in other bones of skeleton as well
ETIOLOGY
unknown
THE TRAUMA HEMORRHAGE THEORY in widely accepted
theory
Trauma heals by organization of clot eventual formation of
connective tissue & new bone
Acc. to the theory, clot breaks down & leaves empty cavity
within the bone
- steady expansion of lesion occurs secondary to altered or
obstructed lymphatic or venous drainage
- this expansion tends to cease when the cyst-like lesion
reaches the cortical layer of bone
- expansion of involved bone is not a common finding in this
TIME LAG B/W INJURY & DISCOVERY OF THE LESION - 1
MONTH to 20 YEARS
CLINICAL FEATURES
Occurs most frequently in young persons
Maxilla mainly develops it
Swelling or rarely pain
HISTOLOGICAL FEATURES
Thin connective tissue membrane lining the cavity
There may be presence of few RBCs, blood pigments or
giant cells adhering to the bone surface
TREATMENT & PROGNOSIS
6 to 8 months for filling of space after surgery
In large spaces, bony chips are used
TRAUMATIC CYST
3. FOCAL OSTEOPOROTIC BONE-MARROW
DEFECT OF THE JAW
Defect of bone closely associated with chronic anemia
Jaw marrow starts haemopoiesis in response of anemia leading to
this defect
CLINICAL FEATURES
Asymptomatic condition
Females are more affected (75%)
Mandible is affected more than maxilla (85%)
RADIOGRAPHIC FEATURES
Poorly defined radiolucency that is found at molar area, a few mm
to cm or more
Poorly defined periphery
HISTOLOGICAL FEATURES
Normal red marrow, fatty marrow or both
Trabeculae of bone present in sections are long,
thin, irregular & devoid of osteoblastic layer
Megakaryocytes & small lymphoid aggregates
may present
TREATMENT
No treatment is necessary
FOCAL OSTEOPOROTIC BONE MARROW DEFECT OF
JAW
4. SURGICAL CILIATED CYST OF MAXILLA
( SINUS MUCOCELE )
Sometimes epithelial cells get implanted in maxillary sinus
during surgical access maxillary sinus
When these cells proliferate they form a cyst there
CLINICAL FEATURES
Middle aged or older patients are mostly affected
Nonspecific, poorly localized pain, tenderness or discomfort
in the maxilla
Extraoral or intraoral swelling
10-20 years after surgery of maxilla or maxillary sinus when
mucocele is infected, the lesion is called MUCOPYOCELE
Common in Japan
RADIOLOGICAL FEATURES
Well defined radiolucency close to maxillary sinus is seen
This radiolucency is anatomically separated from sinus
A filling defect of cyst can be seen after injecting
radiopaque material in sinus
HISTOLOGICAL FEATURES
Cyst lining is formed by pseudostratified ciliated columnar
ep.
Squamous metaplasia may be found if infection or
inflammation is present
Cyst wall is composed of fibrous connective tissue with or
without inflammatory cell infiltration
TREATMENT
Enucleation of cyst. It doesn’t tend to reoccur
SURGICAL CILIATED CYST OF MAXILLA
(C) PHYSICAL INJURIES TO SOFT TISSUES
1. LINEA ALBA
White line seen on the buccal mucosa
extending from the commissures posteriorly at
the level of occlusal plane
Caused by physical irritation & pressure exerted
by the posterior teeth
Usually bilateral
More pronounced in persons having clenching
habit or bruxism
Histologically - Hyperkeratosis & intracellular
edema of epithelium is seen
LINEA ALBA
2. TOOTHBRUSH TRAUMA
Occurs to gingiva & produced by toothbrush
Appears as white, reddish or ulcerative lesions
or linear superficial erosions, involving marginal
or attached gingiva of maxillary canine &
premolar region
HISTOLOGICAL FEATURE
Focal ulceration with formation of granulation
tissue with diffuse chronic inflammatory cell
infiltration
Epithelium shows hyperkeratosis & acanthosis
adjacent to the ulcers
TREATMENT
Symptomatic treatment
Teaching proper brushing technique
3. TRAUMATIC ULCERS
( DECUBITUS ULCERS)
Ulcers of mucous membrane formed due to traumatic injury
MOST COMMON SITES ARE :
Lateral borders of tongue
At occlusal level of teeth in buccal mucosa
Lips
TRAUMA MAY BE DUE TO:
Sharp teeth
Cheek or lip biting
TREATMENT
No treatment is required as these ulcers heal within 7 to 10 days
Symptomatic relief can be provided by lignocaine or any other
topical anesthetic gel
TRAUMATIC ULCER
4. FACTITIAL OR SELF-INDUCED INJURIES
MAY INCLUDE:
Lip biting (morsicatio labiorum)
Cheek biting (morsicatio buccarum)
May be habitual, accidental or psychological
LIP & CHEEK BITING
Holding, biting & tearing of epithelium of lip, buccal mucosa, or tongue, chewing of cheek or
stripping of epithelium using fingers & creating negative pressure by sucking the lips & cheeks
Gingiva may also be involved
CLINICAL FEATURES
Usually bilateral along the occlusal line & vestibular surface of lips
Mucosa appears white & shredded with areas of redness
Ulceration is common
More prominent in females
HISTOLOGICAL FEATURES
Extensive areas of hyperkeratosis with keratin projections
Chronic inflammatory cell infiltration seen in areas of ulceration
TREATMENT
Counseling & psychotherapy are treatment of choice
An acrylic shield will help to prevent the access of teeth to lips & cheeks
5. DENTURE INJURIES
Caused by denture wearing
CAN APPEAR AS:
a) Traumatic ulcer (Sore spots)
b) Generalized inflammation (Denture sore mouth, Denture stomatitis)
c) Inflammatory (fibrous) hyperplasia (Denture injury tumor, epulis fissuratum, redundant
tissue)
d) Inflammatory papillary hyperplasia (Palatal papillomatosis)
e) Denture base intolerance or Allergy
a) TRAUMATIC ULCER (SORE SPOTS)
Caused due to:
- either sharp spicules of bone or high spot on inner aspect of denture
- over extended flanges may also cause sore spots at vestibular area
CLINICAL FEATURES
- Ulcers are small, painful & irregular
- covered by grey necroting membrane
SORE MOUTH
TREATMENT
- Correction of underlying cause
- relief of the flange
- removal of high spots
b) GENERALIZED INFLAMMATION
(DENTURE SORE MOUTH, DENTURE STOMATITIS)
- Characterized by burning erythematous granular mucosa, restricted to area beneath the
denture
CAUSES
- Candida albicans
- Saliva retention in glands
TREATMENT
- Not successful
- denture surface is covered with topical nystatin coating
- For oral condition nystatin tablets(500,000 IU) should de dissolved in mouth* TDS* 14 days
C) INFLAMMATORY (FIBROUS) HYPERPLASIA
(DENTURE INJURY TUMOR, EPULIS FISSURATUM, REDUNDANT TISSUE)
One of the most common tissue rxn to a chronically ill-fitting denture
Occur on buccal mucosa gingiva & angle of mouth
FIBROUS HYPERPLASIA
CLINICAL FEATURES
- mucolabial or mucobucal folds may develop excessive enlarged folds of tissues
HISTOLOGICAL FEATURES
-excessive fibrous connective tissues
- hyperkeratosis is present
- pseudoepitheliomatous hyperplasia is often found
- connective tissue is composed of coarse bundles of collagen fibres with new
fibroblasts or blood vessels
TREATMENT
- Surgical excision of excessive tissues
- New denture should be made
d) INFLAMMATORY PAPILLARY HYPERPLASIA
(PALATAL PAPILLOMATOSIS)
It is the condition in palatal mucosa associated with many erythematous &
oedamatous papillary projections. It is predominantly see in edentulous patients
CAUSES
- Ill fitting dentures
PALATAL PAPILLOMATOSIS
HISTOLOGICAL FEATURES
- papillary projections of keratinized stratified squamous epithelium with vascular
connective tissue present
TREATMENT
- construction of new denture
E) DENTURE BASE INTOLERANCE / ALLERGY
Allergy may be due to denture base material as in cobalt chromium alloy, it may
be due to nickel or in vulcanite dentures, it may be due to sulphur
CLINICAL FEATURES
- generalized inflammation of area in contact with denture
TREATMENT
- First determine the cause of allergy then reconstruct the denture with minimal or
no use of that material
6. MUCOUS RETENTION PHENOMENON
(MUCOCELE, MUCOUS RETENTION CYST)
It is the most common type of salivary & soft tissue cyst
It is either due to retention of mucous or extravasation of mucous
into surrounding tissues
ETIOLOGY
Obstruction (such as salivary calculi) in duct of salivary gland
Trauma due to cheek biting or lip biting
Scar after trauma may also cause retention of mucous in gland
CLINICAL FEATURES
Occur most frequently on the lower lip
May also occur on the palate, cheek, tongue(involving glands of Blandin-
Nuhn) & floor of mouth
Superficial lesion appears as a raised, circumscribed vesicle, several
millimeters to a centimeter or more in diameter with bluish, translucent
cast
Deeper lesion appears as swelling with normal color
LIP MUCOCELE TONGUE MUCOCELE
PATHOGENESIS
Pathogenesis of Retention Cyst
Obstruction of duct -> Pooling of mucous glands ->
Retention cyst is formed
Pathogenesis of Extravasation Cyst
Trauma to Duct -> Mucous escapes in surrounding
tissues -> Chronic Inflammation -> Granulation Tissue
formation around mucous without epithelial lining ->
Extravasation Cyst
HISTOLOGICAL FEATURES
Retention cyst is surrounded by epithelial lining
No epithelial lining is seen in case of extravasation cyst
TREATMENT
Excision of cyst is done completely with underlying salivary
gland acini
7. RANULA
It is a form of mucocele but larger, specifically occur in the floor of mouth in association of ducts
of submaxillary or sublingual glands
CLINICAL FEATURES
Unilateral
Develops as a slowly enlarging painless mass on floor of mouth
In superficial lesions, mucosa may have a translucent bluish color
Deep lesion appear normal
May interfere with speech & mastication
HISTOLOGICAL FEATURES
Similar to mucocele except that a definite lining is sometimes present
TREATMENT & PROGNOSIS
Treatment either marsupialization or more often excision of the entire sublingual gland
8. RETENTION CYST OF MAXILLARY SINUS
(Secretory cyst of maxillary antrum, mucocele of maxillary sinus,
mucosalcyst of maxillary sinus)
These are mucous retention cysts of mucous glands, lining the maxillary sinus
CLINICAL FEATURES
asymptomatic
RANULA
Discomfort in cheek or maxilla may be present
Pain & soreness of face & teeth & numbness of upper lip
RADIOLOGICAL FEATURES
Lesion appears as a well-defined, homogenous, dome-shaped or hemispheric radiopacity,
varying in size from a tiny lesion to one completely filling the antrum, arising from antrum &
superimposed on it
TREATMENT
Cysts either persists unchanged or disappears spontaneously within a relatively short period
No treatment is necessary
9. SIALOLITHIASIS
(Salivary duct stone, Salivary duct calculus)
A stone in salivary ducts or glands is called Sialolithiasis
Formed by deposition of calcium salts around a central nidus(formed by bacteria, debris,
foreign bodies or epithelial cells)
CLINICAL FEATURES
Severe pain occurs during meal time especially when eating citrus fruits
Salivary gland is painful & swollen
On palpitation stone may be detected in ducts
Sialolithiasis is found mostly in submandibular gland because of:
- Tortuous path of Wharton's duct
- Mucinous secretion of the gland
- Gravitational effect of saliva inside duct
CHEMICAL & PHYSICAL FEATURES
Round, ovoid or elongated
Measure just a few millimeters or 2 cm or more in diameter
Involved duct contain single or multiple stones
Surface of calculi is rough, which may cause squamous metaplasia of duct lining
Usually yellow & occasionally white or yellowish-brown in color
Calculi consist of calcium phosphates & smaller amount of calcium carbonates, organic
materials & water
TREATMENT & DIAGNOSIS
Small calculi may sometimes be manipulated or increasing the salivation by sucking a
lemon, leading to expulsion of stone
I.V. injection of antibiotic like nafcillin is given for bacterial infection due to persistent
obstruction of duct
Larger stones require surgical removal
Piezoelectric shock wave lithotropsy is alternative to surgical removal
10. MAXILLARY ANTROLITHIASIS
(Antral rhinolith)
Rare condition
Defined as complete or partial calcific encrustation of an antral foreign body, either
endogenous or exogenous, which serves as a nidus
Endogenous nidus consist of a dental structure such as a root tip or may simply be a fragment
of soft tissue, bone, blood or mucous
Exogenous nidus is uncommon but may consist of snuff paper
CLINICAL FEATURES
Occur at any age in either sex
May be a complete absence of symptoms
Some cases are marked by pain, sinusitis, nasal obstruction, foul discharge & epistaxis
TREATMENT
Antrolith should be surgically removed
11. RHINOLITHIASIS
Are calcareous concretions occurring the nasal cavity
This uncommon lesion is formed by calcification of intranasal endogenous or exogenous foreign
material
Reported in all ages
May present for years & frequently give rise to odorous discharge, symptoms of nasal
obstruction, sinusitis, epiphora as well as pain & epistaxis
12. RADIATION INJURY
(A) X-RAYS
Can ionized the water molecules present inside the cells & form highly reactive radicals.
These radicals can damage the cell by various manners as:
- They can cause mutation
- They can damage enzymes
- They may interrupt cell division
EFFECTS OF X-RAYS ON ORAL MUCOSA
Erythema of mucosa occurs initially
Then Mucositis occurs
Now mucosa becomes ulcerative with fibrinous exudation. Taste sense is also lost
Taste sensation is returned 2 to 4 months after treatment of x-ray therapy
EEFECTS OF X-RAYS ON SALIVARY GLANDS
Xerostomia occurs due to loss of acinar cells, decrease in secretory granules &
inflammation in connective tissue of salivary glands
May cause permanent dryness of mouth
Artificial saliva (Methyl cellulose) should be prescribed
EFFECT OF X-RAYS ON TEETH
During formitive stage of teeth can cause andodontia or defective root formation
After development of teeth, may cause cervical caries that may lead to fracture of crown at cervical
third
TREATMENT : Fluoride treatment & proper oral hygiene
EFFECT ON BONE
Have damaging effect on bone forming cells
Blood vessels necrosed
When these changes are associated with trauma & infection, OSTEORADIONECROSIS occurs
This mostly occurs when infected tooth is present in the LINE OF FIRE
(B) LASER RADIATIONS
EFFECTS ON TEETH
Enamel – Chalky spots & craters with small holes are seen
Dentin exhibit a burnt appearance
Pulp – Hemorrhagic necrosis present
- Inflammatory cell infiltration is seen
- Necrosis of odontoblastic layer
EFFECTS ON SOFT TISSUES
Ulcers are formed in epithelium
13. CERVICOFACIAL EMPHYSEMA
Emphysema is swelling due to presence of gas or air in interstices of connective tissue
CAUSES
Blow of air in periodontal pockets or root canals with use of air syringe
CLINICAL FEATURES
Painful unilateral swelling with feeling of crepitus on palpation
TREATMENT
Antibiotics are given to avoid connective tissue infection, hydration, massages,
sialogagues, & compression
Puncture of subcutaneous tissues can be done with sharp needle
Venous air embolism may occur as complication leading to death
CHEMICAL INJURIES OF THE
ORAL CAVITY
The oral cavity frequently manifests a serious
reaction to a wide variety of drugs and
chemicals.
The tissue reaction is that of a local response to
a severe irritant or even a caustic used
injudiciously.
The two main types that are of dental interest are:
1.Drug allergy or stomatitis
2.Contact stomatitis
NONALLERGIC REACTION TO DRUGS
AND CHEMICALS USED LOCALLY.
Irritants or caustics which are used by the
dentist in various therapeutic are technical
procedures induces a non allergic reactions
when used locally.
Some of these substances are discussed
separately below:
1.Aspirin (Acetylsalicylic Acid)
2.Endodontic Materials.
CONTD….
2. Sodium Perborate.
3.Hydrogen Peroxide.
4.Phenol.
5.Silver Nitrate.
6.Trichloroacetic Acid.
7.Volatile Oils.
8.Miscellaneous Drugs and chemicals.
NONALLERGIC REACTION TO DRUGS
AND CHEMICALS USED SYSTEMICALLY.
Arsenic – severe gingivitis, ulceration.
Bisphosphonate – osteonecrosis.
Bismuth – thin blue/ black line on mar - gingiva
Dilantin Sodium – gingival hyperplasia
Cyclosporine – peri oral hyperesthesia
Nifedipine – gingival enlargement
Lead poisoning(plumbism) – lead line on gingiva
Mercury – increased flow of saliva, metallic taste,
Hyperemia and swelling of S gland, tongue and
gingiva
Acrodynia (Pink disease, Swift’s disease)
It is an uncommon disease of unknown etiology,with
striking cutaneous manifestations.
The cause of the disease - mercurial toxicity reaction
C/F : The skin becomes red or pink. The skin over
the affected areas peels frequently during the
course of the disease.
O/M : Profuse salivation and often ‘dribbling.’
The gingiva becomes extremely sensitive or
painful and may exhibit ulcerations.
Bruxism, loosening and premature shedding
of teeth, child will extract loose teeth with
his/her fingers.
Masticationis difficult because of the pain.
Silver (Argyria, argyrosis)
Chronic exposure to silver compounds may occur as an
occupational hazard or as the result of therapeutic use of
silver compounds
Amalgam tattoo appears as macules, or rarely, as slightly
raised black, blue, or gray lesion.
Amalgam tattoo of oral mucous membrane is a
relatively
common finding in dental practice, generally occurring in
one
of four ways, according to Buchner and Hansen:
(1) From condensation in gingiva during amalgam
restorative work,
(2) from particles entering mucosa lacerated by revolving
instruments during removal of old amalgam restorations,
(3) from broken pieces introduced into a socket or beneath
periosteum during tooth extraction, or
(4) from particles entering a surgical wound during root
canal treatment with a retrograde amalgam filling.
Tetracycline
Discoloration of either deciduous or permanent teeth
may occur as a result of tetracycline deposition during
prophylactic or therapeutic regimens instituted either
in the pregnant female or postpartum in the infant.
The severity of the staining by tetracycline is
determined by the stage of tooth development at the
time of drug
administration.
C/F : yellowish or brownish-gray discoloration
OCCUPATIONAL INJURIES OF ORAL CAVITY:
OCCLUSAL TRAUMA :
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