WATER :
The Solvent for
Biochemical Reactions
What Does Life Require?
Molecule: two or more atoms
held together by chemical
bonds
Example: Water
Water molecule: two hydrogen
atoms bonded to one oxygen
atom
Molecular Geometry of Water
refers to the arrangement of atoms within a given
molecules.
Basic Assumption of VSEPR –
Electrons in chemical bonds (single, double or triple
bond) and unshared electrons pairs are negative
charge centers that repel each others, they tend to
move as far apart from each other as possible.
But the presence of lone pair causes deviation,
because lone pair exerts a greater force of repulsion.
The lone pair tends to push bonding pairs closer
together, thereby decreasing the bond towards them.
Ex. H2O
What Does Life Require?
The Properties of Water
Water is a polar molecule:
◦ Oxygen side is slightly
negative
◦ Hydrogen side is slightly
positive
◦ Electronegativity = how
strongly the atoms pull
electrons
When molecules have no
charges, they are nonpolar
Figure 2.4
Electronegativity Values
Electronegativity – the tendency of an atom to
attract electrons to itself in a chemical bond.
Elcetronegativity Bond Type
Difference
0 Non polar
Up to 1.8 Polar
1.8 and above Ionic
Solvent Properties of Water
2.1 What Does Life Require?
The Properties of Water
Due to its polarity, water is a good solvent
◦ Solute: what is being dissolved
◦ Solution: the solute in the solvent
Solvent Properties of Water
What Does Life Require?
The Properties of Water
Hydrogen bond: the weak attraction between
the hydrogen atom of one water molecule
and the oxygen atom of another
Water molecules tend to stick together:
cohesion
High heat capacity
High heat of vaporization
High heat of fusion
Solvent Properties of Water
Solvent Properties of Water
2.1 What Does Life Require?
The Properties of Water
Water can dissolve
salts and hydrophilic
(water–loving)
molecules because it
is polar.
Figure 2.6
Solvent Properties of Water
Solvent Properties of Water
Solvent Properties of Water
Solvent Properties of Water
2.1 What Does Life Require?
The Properties of Water
Water can dissolve acids and bases.
◦ Acid = a substance that donates H+ ions to
solution
◦ Base = a substance that accepts H+ ions
2.1 What Does Life Require?
The pH scale is a measure of the
relative amounts of acids and
bases in a solution.
◦ pH greater than 7 = basic
◦ Pure water pH = 7 = neutral
◦ pH lower than 7 = acidic