Mrutyunjay Rasa
by
Dr . Vikas Saroch
OBJECTIVES
To elaborate pharmaceutical process
To understand pharmaco kinetics and dynamics
To understand probable mode of action
To understand Pharmacopoeial standards
To compare with different varieties of Mrutyunjay rasa
Introduction
Widely used in Jwara
Easy to prepare
Explained in most of the classical texts
More than 10 types
With different ingredients , indications and method of
preparation
Majority of ingredients contains Parada and Gandhaka
Pharma companies taken reference from Bhaisajya Ratnavali.
AFI and PSAF also explained the same
Different References
Bhaisajya Ratnavali Jvarachikista
2 types explained
5th chapter 510-519
5th chapter 758-759
In Bharat Bhaisajya Ratnakar about 10 different
formulation explained under the name of Mrutyunjay
rasa .
Bhaishajya Ratnavali Jvarachikista 5th chapter Sh.No. 510-519
Visa (Aconitum ferox wall) Rt . Tr 1 Part
(Gomutra Shodhita)
Marica (Piper nigrum linn) Fr. 1 Part
Pippali (Piper longum) Fr. 1 Part
S. Gandhaka - 1 Part
S.Tankana - 1 Part
Hingula shodhita( Jambira Swarasa) - 2 Parts
Or Parada 1 Part
Acc. To Bhaishajya Ratnavali Jwarachikista 758-759
Shudh Parada 1 Part
Shudh Gandhaka 2 Parts
Shudh Tankana 3 Part
Shudh Vatsanabh 8 Part
Dhatura Beeja Churna 16 Part
Trikatu Churna 32 Part
Gandhak
Grahya Swaroopa:
Shooka pitcha
Navaneeta Samaprabha
Khatina, Snigda (Ay.P. 2/20)
Properties:
Katu, Tikta, Kashya Rasa
Usna Virya
Deepana,Pachana, Agnikari,
Rasayana, Amanashaka.
Tankan
Properties :
Katu rasa
Usna Virya
Ruksha ,Tikshna Guna
Balya, Agnivardhaka,
Anti-dot for
Vatsnanabha.
Hingula Grahya Lakshana
Sweta rekha
Hamsa pada
Pravalabha (red)
Properties:
Tikta, Katu, Kashaya
Usna Virya
Deepana, Agnivardaka,
Rasayana, Sarvadoshagna,
Ruchya
Vatsanabh
(Aconitum ferox)
Properties :
Usna , Jwaraghana,Balya
Indication :
Jwara, Kasa, Shwasa,
Vatroga,Grahani
Dose : 1/16 – 1/8 ratti
Marich (Piper nigrum Linn)
Properties :
Pachaka
Agnideepaka,Ruchikar
Swedakar
Contains piperin which
helps in reducing fever
specially in malaria .
Pippali (Piper longum)
Properties :
Rasayan ,Deepana,
Paachana,Usna
Indication :
Agnimandya ,Kasa,
Swasa,Jeernajwara
PREPARATION
Shudh Gandhak, Shudh Vatsanabh, Marich Churna, ShudhTankan,
Pippali Churn, Shudh Hingula or Parada
Mixed together to form a fine blend
Mixture is processed with Aradrak/Jambira Swaras
Till a uniform blend is achieved
Mrutyunjay Rasa
Mrtyunjaya Rasa (BR,Jvaradhikara;409-411) AFI
20:30
Visa (Aconitum ferox wall) Rt . Tr 1 Part
(Gomutra Shodhita)
Marica (Piper nigrum linn) Fr. 1 Part
Pippali (Piper longum) Fr. 1 Part
S. Gandhaka - 1 Part
S.Tankana - 1 Part
Hingula shodhita (jambira Swarasa) - 2Part
Or rasa (Parada) – Shudha 1 Part
Dose : 125mg
Anupana : Mastu, Ardraka Swarasa, Honey
Important therapeutic use: Sarva Jvara,Visama Jvara,
Jirna Jvara
Baidyanath (Bhaisajya Ratnavali)
Ingredients
Parad ,Gandhak, Hingula ,Tankan, Vatsanabh, Marich,
Pipali, Jambiri Nimbu Swaras.
Therapatic uses:
Indicated in general debility of children, effective in
fever & sannipat Jwara. Indigestion
Dosage:
1 tab. with madhu. twice a day.
Visa, Maricha, Pippali, Gandhaka, Tankan , Hingula,
Rasa
Indication : Jwara
Dose : 125mg
Anupana : Mastu , Ardraka Swarasa
Manufacture : Baidyanath, Dabur, Dhanwantri,
Dindyal, UMA , Gurukal Kangri , UAP , Zandu
Packing : 40 tab
Price : 20-25 Rs
Analytical Findings / Quality Test
Organoleptic characters
• Colour - Brick Red
• Smell - Faint
• Touch - Medium
• Taste - Astringent
Tablet Hardness Test
Tablet Disintegration Test
Quantative estimation
Free sulpher Not less than 13.2 % w/w
Not more than 14.9 % w/w
Sulphur Not less than 17.9 % w/w
Not more than 19.3 % w/w
Mercury Not less than 24.3 % w/w
Not more than 29.7 % w/w
Iron Not more than 1.265 % w/w
Sodium Not more than 18.12 % w/w
Sulphate Not more than 3.53 % w/w
Chloride Not more than 1.0 % w/w
Magnesium Not more than 1.0 % w/w
Phosphate Not more than 3.66 % w/w
Silica Not more than 1.03 % w/w
(Acid insoluble material)
Ash value Not less than 12.4 % w/w
Not more than 19.0 % w/w
Acid insoluble ash Not less than 0.66 % w/w
Not more than 1.90 % w/w
Dose - 100 to 250mg
Summary
Popularly used drug in various fevers.
Easily prepared using easily available ingredients.
Shows rapid action.
Widely available with a number of manufacturers
producing it.
Most of the companies use reference from Bhaishajya
Ratnavali.
References
Bhaishajya Ratnavali
Bharat Bhaishajya Ratnakar
Rasa Ratan Samuchaya
Rasa Raja Sundra
Rasa Chandashu
Ayurveda Prakesha
Yoga Ratanakar
AFI
PSAF
www.nlam.in
Thank u…..