URINARY INCONTINENCE
Marsha K. Guess, MD, MS Assistant professor and Fellowship Director Section of Urogynecology & Reconstructive Pelvic Surgery The Departments of Obstetrics, Gynecology & Reproductive Sciences & Urology
Urinary Incontinence
The involuntary loss of urine
STATISTICS:
10-60% of women report urinary incontinence
Only 10-20% seek medical care Billions of dollars spent annually on incontinence products (in North America)
Nygaard, I. et al. JAMA 2008;300:1311-1316.
PSYCHOSOCIAL IMPACT
Higher prevalence of depression, embarrassment, loss of self esteem, anxiety Decrease in excursions outside home, social interactions, sexual activity
Major factor in the decision to place a relative in a nursing home
TYPES OF URINARY INCONTINENCE
Genuine Stress Urinary Incontinence
Detrusor Instability
Intrinsic Sphincter Deficiency
Overflow Incontinence Functional/Transient incontinence
PATHOPHYSIOLOGY OF SUI
SYMPTOMS ASSOCIATED WITH URGENCY INCONTINENCE
Complaint
Daytime frequency
Nocturia Nocturnal enuresis Urgency Urinary incontinence urgency
Definition
voids too often/day
voids too often/night loss of urine during sleep sudden desire to void involuntary loss of urine with or immediately preceded by
Abrams P et al. Am J Obstet Gynecol. 2002;287(1):116-126.
INTRINSIC SPHINCTER DEFICIENCY
Problem with ability of urethra to close
Drain pipe urethra
ISD RISK FACTORS
Age Trauma/childbirth Previous Incontinence Surgery
PATIENT EVALUATION
Explore symptoms: duration frequency precipitants most bothersome
Focus on medical, surgical, neurological & genitourinary history
diabetes mellitus multiple sclerosis mental status
hx of previous incontinence surgery failure of previous pharmacotherapy symptoms of prolapse
Review voiding patterns/fluid intake
Obtain voiding diary
PHYSICAL EXAMINATION
Problem with support of urethra Goal: stabilize urethra
Normal
Abnormal
EVALUATION OF URINARY INCONTINENCE
Post-void residual
Urinalysis
Urine culture
Urine cytology
HbA1C Voiding diary Urodynamics Cystoscopy
VOIDING DIARY
Voiding Diary 11/18/05
Time Amount 100cc 50cc 25 cc 150cc 100cc 150cc 50cc 75cc 90cc 120cc 100cc 100cc 50cc 25 cc 160cc 100cc 150cc 50cc 75cc 90cc 120cc 2130 Leaks 0 1 2 1 0 0 0 1 0 0 0 0 1 0 1 0 1 0 0 0 1 9 7:00am 7:45am 8:15am 9:00am 9:30am 11:00am 1:15am 3:00pm 5:00pm 6:30pm 7:30pm 8:00pm 8:45pm 9:15pm 10:00pm 10:30pm 11:00pm 1:15am 3:00am 5:00am 6:15am Total Drinks cup with meds 8oz water 12oz coffee 8oz water 12 oz coffee
cup with meds 8oz water
8oz water
2160
URODYNAMICS
CYSTOSCOPY
INDICATIONS FOR URODYNAMIC TESTING
Previous failed surgery When surgery is planned Uncertain etiology to incontinence Concomitant prolapse (Potential incontinence) Failed medical treatment
CONSERVATIVE MANAGEMENT OF SUI
Behavior modification
Bladder Training
Physiotherapy Mechanical devices Pharmacological Therapy
BIOFEEDBACK
GSUI PELVIC FLOOR EXERCISES
Kegels alone vs. Vaginal cones vs. Pressure biofeedback
All improved symptoms and QOL No significant difference between groups
Laycock et al. 2001
GSUI
WEIGHT LOSS
13 morbidly obese women
Results:
9/12 with resolution of urinary symptoms post-op Objective and subjective improvement of stress and urge incontinence
Bump et al. 1992 10 moderately obese women (mean BMI 38.3) 4 or more episodes of incontinence /day
Results:
50% in incontinence episode with > 5% weight loss
Subak et al. 2002
GSUI PESSARY
SURGICAL MANAGEMENT OF SUI
SLINGS FOR SUI
CONSERVATIVE MANAGEMENT OF UUI
Behavior modification
Bladder Training
Pharmacological
Therapy
Electrical Stimulation
ANTICHOLINERGIC SIDE EFFECTS
Dry mouth Blurred vision Drowsiness Tachycardia
Constipation
ANTICHOLINERGIC CONTRAINDICATIONS
Narrow angle glaucoma
Intestinal obstruction Cardiac arrhythmia Myasthenia gravis
ELECTRICAL STIMULATION FOR UUI
BULKING AGENTS FOR ISD
BULKING AGENTS FOR ISD
BULKING AGENTS FOR ISD
BOTOX
CONCLUSION
Urogynecology includes a wide variety of lower urinary tract and pelvic floor disorders Patient satisfaction is optimized when meticulous care is taken to adequately evaluate patients and individualize therapy Patience is a virtue!!!!