JSPM University Pune
S.Y. B. Tech (Regular & Lateral)
Semester- III/IV
Course Type: IOC Course Title: Bioengineering
Course Code: Teaching Scheme: Examination
250GBTB01_ (Hrs./Week) Scheme:
Credits: 2 Lecture (L): 2 Theory (Th): 100 Marks
Tutorial (T): 0
Practical(P): 0
Experiential Learning (EL): 0
Prerequisite Courses, if any:
Biology
Course Objectives:
● To apprehend with a solid foundation in the fundamental concepts of bioengineering,
including cell structure, biomolecules, and human anatomy.
● To introduce insight of the principles and applications of biomedical engineering,
covering various medical imaging devices and biomedical recorders.
● To acquaint students with the integration of artificial intelligence in healthcare,
exploring its applications, limitations, and ethical considerations.
● To equip students with knowledge of computational models and methods used in
biological research and data analysis.
● To develop proficiency in bioinformatics tools and databases for analyzing genomic
and proteomic data and understanding drug design.
● To explore bio-inspired systems and their applications in environmental remediation,
energy harvesting, and storage.
Course Outcome: Upon completion of the course, learners will be able to:
CO1: Identify biological concepts essential for engineering applications.
CO2: Apply knowledge of medical imaging devices and biomedical recorders to real-
world biomedical engineering problems.
CO3: Assess AI technologies in healthcare settings, to address their potential and
associated ethical issues.
CO4: Illustrate computational methods to simulate biological processes and analyze
complex biological data.
CO5: Illustrate on bioinformatics tools and techniques to analyze genomic and proteomic
data, and participate in drug design and development projects.
CO6: Describe bio-inspired approaches for environmental remediation, energy
solutions, and other technological applications.
Course Contents
Unit I Foundations of Bioengineering (5Hrs)
Cell structure and function, Biomolecules: Nucleic acids, proteins, amino acids, lipids
and carbohydrates, Human anatomy and physiology, Respiratory system, Central
Nervous System: resting and action potential generation, Cardiovascular System:
Structure and function of a heart
Unit II Biomedical Engineering (5Hrs)
Definition, types of medical imaging Devices, working principle, applications, limitations:
MRI, CT scans, and X-rays, Design and application of materials in medical devices and
implants: Pacemaker and Continuous Glucose Monitoring Unit, Biomedical recorders:
Electrocardiogram (ECG), Electroencephalogram (EEG), Electromyogram (EMG).
Unit III Healthcare Engineering (5Hrs)
Introduction to Artificial Intelligence in healthcare, Application of AI in Healthcare and
Research: Drug Discovery, Clinical trials, AI powered stethoscope, Limits, Ethical and
Social issue, Introduction to Robotics and Automation in healthcare, Robot assisted
recovery and rehabilitation
Unit IV Computational Biosciences (5Hrs)
Introduction to computational models in biology, Applications of computational methods
in biological research, Simulation techniques for studying biological processes, Modeling
complex biological systems; Use of tools in understanding diseases, Machine Learning
in Biological Data Analysis.
UNIT V Bioinformatics Perspective (5Hrs)
Major bioinformatics databases (e.g., NCBI, EMBL), Tools for sequence alignment (e.g.,
BLAST), Techniques for analyzing genomic and proteomic data, Next-generation
sequencing data analysis, Structural Bioinformatics and Molecular Modeling: Protein
structure prediction methods, Molecular docking and drug design.
Unit VI Bio-Inspired Systems (5Hrs)
Introduction to biomimetics and biomimicry; Bio-inspired Environmental Remediation and
its applications. Biomimetic approaches to energy harvesting and storage (e.g.,
photosynthesis-inspired solar cells, energy-efficient designs); Biofuels and biologically
inspired energy conversion technologies.
Learning
Resources
Textbooks:
1. Lehninger principles of biochemistry fourth edition.
2. Joseph D. Bronzino “The Biomedical Engineering Handbook Third Edition”
Reference Books:
1. Chinmaya Panda, R. Shreya, and Lalit M. Pandey “Importance of Biology for
Engineers: A Case Study”
2. R. S. Khandpur “Handbook of Biomedical Instrumentation.”
3. Ian Peate and Murlitharan Nair “Fundamentals of Anatomy and Physiology”
Allison M. Okamura, Maja J. Mataric, Henrik I. Christensen “Medical and Health care
Robotics.
MOOC / NPTEL Courses:
● NPTEL Course on “Next Generation Sequencing Technologies: Data Analysis and
Applications”, By Prof. Riddhiman Dhar | IIT Kharagpur
https://onlinecourses.nptel.ac.in/noc24_bt64/preview
● NPTEL Course on “Introduction to Dynamical Models in Biology”, By Prof. Biplab Bose,
IIT Guwahati.
https://onlinecourses.nptel.ac.in/noc24_bt41/preview
Additional Web Resource’s:
https://onlinecourses.nptel.ac.in/noc24_bt70/preview
