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Minoxidil Safety Data Sheet

The Safety Data Sheet for Minoxidil, prepared on August 7, 2015, identifies the product's hazards, including acute toxicity and skin/eye irritation, and provides emergency contact information. It outlines first aid measures, handling and storage precautions, and personal protective equipment requirements. The document also includes regulatory information and indicates that Minoxidil is not classified as a dangerous good for transport.

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sharmaarun002
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0% found this document useful (0 votes)
45 views7 pages

Minoxidil Safety Data Sheet

The Safety Data Sheet for Minoxidil, prepared on August 7, 2015, identifies the product's hazards, including acute toxicity and skin/eye irritation, and provides emergency contact information. It outlines first aid measures, handling and storage precautions, and personal protective equipment requirements. The document also includes regulatory information and indicates that Minoxidil is not classified as a dangerous good for transport.

Uploaded by

sharmaarun002
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Safety Data Sheet

(Minoxidil)
DATE PREPARED: 8/7/2015

Section 1. Product and Company Identification

Product Name Minoxidil


CAS Number 38304-91-5

Parchem - fine & specialty chemicals EMERGENCY RESPONSE NUMBER


415 Huguenot Street CHEMTEL
New Rochelle, NY 10801 Toll Free US & Canada: 1 (800) 255-3924
(914) 654-6800 (914) 654-6899 All other Origins: 1 (813) 248-0585
[Link] info@[Link] Collect Calls Accepted

Section 2. Hazards Identification

Classification of the substance or mixture


Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Eye irritation (Category 2A), H319
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335

GHS Label Elements

Pictograms:

Signal word: WARNING

Hazard and precautionary statements


Hazard Statements
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.

Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapors/spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink, or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

P302 + P352 IF ON SKIN: Wash with plenty of soap and water.


P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing.
P312 Call a POISON CENTER or doctor/ physician if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions on this label).
P330 Rinse mouth.
P332 + P313 If skin irritation occurs: Get medical advice/ attention.
P337 + P313 If eye irritation persists: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.

Hazards not otherwise classified (HNOC) or not covered by GHS: None

Section 3. Composition / Information on Ingredients

Common Name Minoxidil


Synonym(s) 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide; 6-(1-Piperidinyl)-2,4-
pyrimidinediamine 3-oxide
Formula C9H15N5O
CAS Number 38304-91-5

Section 4. First Aid Measures

Description of first-aid measures


General advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
Move out of dangerous area.
Inhalation: If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
Skin contact: Wash off with soap and plenty of water. Consult a physician.
Eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth with water.
Consult a physician.

Most important symptoms and effects, both acute and delayed: The most important
known symptoms and effects are described in the labelling and/or in section 11
Indication of any immediate medical attention and special treatment needed: No
data available

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

Section 5. Firefighting Measures

Extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon
dioxide.

Special hazards arising from the substance or mixture: Carbon oxides, nitrogen oxides
(NOx)
Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Further information: no data available

Section 6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Use personal


protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see
section 8.
Environmental precautions: Do not let product enter drains.
Methods and materials for containment and cleaning up: Pick up and arrange disposal
without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Reference to other sections: For disposal see section 13.

Section 7. Handling and Storage

Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and
aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures
for preventive fire protection.
Conditions for safe storage, including any incompatibilities: Keep container tightly closed
in a dry and well-ventilated place.

Section 8. Exposure Controls / Personal Protection

Control parameters
Components with workplace control parameters: Contains no substances with
occupational exposure limit values.

Exposure controls
Appropriate engineering controls: Handle in accordance with good industrial hygiene and
safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment


Eye/face protection: Safety glasses with side-shields conforming to EN166 Use equipment for
eye protection tested and approved under appropriate government standards such as NIOSH (US) or
EN 166(EU).

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory
practices. Wash and dry hands.
Body Protection: Complete suit protecting against chemicals. The type of protective equipment
must be selected according to the concentration and amount of the dangerous substance at the
specific workplace.
Respiratory protection: For nuisance exposures use type P95 (US) or type P1 (EU EN 143)
particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN
143) respirator cartridges. Use respirators and components tested and approved under appropriate
government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure: Do not let product enter drains.

Section 9. Physical and Chemical Properties

Information on basic physical and chemical properties


Appearance: Solid
Color: White
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/range: 272 - 274°C (522 - 525°F) - dec.
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient (n-Octanol/water): No data available
Auto-ignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available

Other safety information: No data available

Section 10. Stability and Reactivity

Reactivity: No data available


Chemical stability: Stable under recommended storage conditions.

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

Possibility of hazardous reactions: no data available


Conditions to avoid: No data available
Incompatible materials: Oxidizing agents

Hazardous decomposition products


Other decomposition products: no data available
In the event of fire: see section 5

Section 11. Toxicological Information

Information on toxicological effects


Acute toxicity
LD50 Oral - rat - 1,321 mg/kg
Dermal: no data available

Skin corrosion/irritation: No data available


Serious eye damage/eye irritation: No data available
Respiratory or skin sensitization: No data available
Germ cell mutagenicity: No data available

Carcinogenicity
IARC: No component of this product, present at levels greater than or equal to 0.1%, is identified as
probable, possible or confirmed human carcinogen by IARC.
ACGIH: No component of this product, present at levels greater than or equal to 0.1%, is identified
as a carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product, present at levels greater than or equal to 0.1%, is identified as
a known or anticipated carcinogen by NTP.
OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified
as a carcinogen or potential carcinogen by OSHA.

Reproductive toxicity
Reproductive toxicity - rat - Subcutaneous
Maternal Effects: Parturition. Effects on Newborn: Stillbirth. Effects on Newborn: Live birth index (#
fetuses per litter; measured after birth).

Developmental Toxicity - rat - Subcutaneous


Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus). Specific Developmental
Abnormalities:
Musculoskeletal system. Effects on Newborn: Stillbirth.
Developmental Toxicity - rat - Subcutaneous
Specific Developmental Abnormalities: Musculoskeletal system. Effects on Newborn: Behavioral.
Developmental Toxicity - rat - Subcutaneous
Specific Developmental Abnormalities: Musculoskeletal system. Effects on Newborn: Physical.

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

Specific target organ toxicity - single exposure: Inhalation - May cause respiratory
irritation.
Specific target organ toxicity - repeated exposure: no data available
Aspiration hazard: no data available

Additional Information
RTECS: UV8200000
Palpitation, Rash, To the best of our knowledge, the chemical, physical, and toxicological properties
have not been thoroughly investigated.
Stomach - Irregularities - Based on Human Evidence

Section 12. Ecological Information

Toxicity: no data available


Persistence and degradability: no data available
Bioaccumulative potential: no data available
Mobility in soil: no data available
Results of PBT and vPvB assessment: PBT/vPvB assessment not available as chemical safety
assessment not required/not conducted
Other adverse effects: no data available

Section 13. Disposal Considerations

Waste Treatment Methods: Dispose of product and contaminated packaging in accordance


with all local, state, and federal environmental control regulations.

Section 14. Transport Information

DOT (US): Not dangerous goods


IMDG: Not dangerous goods
IATA: Not dangerous goods

Section 15. Regulatory Information

SARA 302 Components


SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III,
Section 302.

SARA 313 Components


SARA 313: This material does not contain any chemical components with known CAS numbers that
exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards: Acute Health Hazard, Chronic Health Hazard

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Safety Data Sheet
(Minoxidil)
DATE PREPARED: 8/7/2015

Massachusetts Right to Know Components: No components are subject to the Massachusetts


Right to Know Act.
Pennsylvania Right to Know Components
Minoxidil (CAS-No. 38304-91-5)
New Jersey Right to Know Components
Minoxidil (CAS-No. 38304-91-5)

California Prop. 65 Components: This product does not contain any chemicals known to State
of California to cause cancer, birth defects, or any other reproductive harm.

HMIS Rating
Health: 2*
Flammability: 0
Reactivity: 0

NFPA Rating
Health: 2
Flammability: 0
Reactivity: 0

Section 16. Other Information

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the present state of
our knowledge and is applicable to the product with regard to appropriate safety precautions. It
does not represent any guarantee of the properties of the product.

REVISION DATE: 8/7/2015

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