[go: up one dir, main page]
Scribd
Upload
3 views1 page

Summary

This document discusses the importance of analytical methodologies in pharmaceutical quality assurance, particularly in response to evolving manufacturing techniques and regulatory standards. It outlines the development of novel liquid chromatographic assays and the optimization of experimental conditions to enhance accuracy and reliability in drug analysis. The study aims to create efficient analytical techniques for key substances that can aid in quality control and process development of pharmaceuticals.

Uploaded by

rafiresearch2
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
3 views1 page

Summary

This document discusses the importance of analytical methodologies in pharmaceutical quality assurance, particularly in response to evolving manufacturing techniques and regulatory standards. It outlines the development of novel liquid chromatographic assays and the optimization of experimental conditions to enhance accuracy and reliability in drug analysis. The study aims to create efficient analytical techniques for key substances that can aid in quality control and process development of pharmaceuticals.

Uploaded by

rafiresearch2
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 1

SUMMARY AND CONCLUSION

Analytical methodologies have taken on a significant role in pharmaceutical


quality assurance. Changes in manufacturing techniques, as well as regulatory
agencies' establishment of limits for individual and overall drug contaminants, are
occurring on a regular basis. Pharmacological analytical approaches that include
physical and chemical procedures are used to achieve this goal.

We're working to create novel liquid chromatographic assays for specific


medications as part of this study. The chemistry of chromomeric reagents, the
reactions used in this study, is the focus of this study. New chromatographic
procedures are often developed by optimising experimental circumstances (e.g. pH
effects; reagent concentration and order; time and temperature retention between
additions; solvent effects; colour development and stability; optical properties,
etc.). Percent range of error; selectivity; precision; standard deviation; standard
deviation; accuracy (comparison; assessment of significance by t-test and recovery
experiments; selectivity; precision; standard deviation).

Aside from studying the HPLC system components (solvent delivery


systems and degassing systems, as well as gradient elution devices and sample
introduction systems for liquid chromatography detectors), this study also focuses
on HPLC performance calculations, such as the relative retention, theoretical
plates per metre and the height of theoretical plates equal to the plate's height
equivalent to theoretical plate (recovery, response function, sensitivity, precision
and accuracy).
The author attempted to create novel analytical techniques for several key
substances in pure and pharmaceutical dose forms while keeping this in mind in
the current work. Simple, fast, trustworthy, and dependable approaches are used
in the thesis's methods section. Quality control and process development of bulk
pharmaceuticals might benefit from the techniques.

You might also like