DEPARTMENT OF MICROBIOLOGY
MODULE EXAM – 1
PAPER: GENERAL MICROBIOLOGY
FILL IN THE BLANKS: 90 x ½ = 45
1. __________________________ introduced vaccine for hydrophobia.
2. In a bacterial cell ______________ are considered as the centres for protein synthesis.
3. ________________________________ is the widely accepted manual for the systematic
classification of microorganisms.
4. _______________________ are extrachromosomal genetic elements.
5. The highest magnification in a light microscope is _____________.
6. The ability of the microscope to show too closely placed particles as distant as apart is referred as
_________________________.
7. Name one granular staining method ___________________.
8. ________________ refers to aberrant pleomorphic bacterial structures without definite shape.
9. Composition of the Gram-negative bacterial cell wall that accounts for endotoxicity is
___________________.
10. _____________________________ method of electron microscopy uses heavy metals to make 3D
pictures of higher clarity.
11. Viruses are best observed by ___________________ microscope.
12. Arrangement of flagella all around the surface of the bacterial cell is ____________________.
13. Bacteria which can grow best at temperatures above 55°C are called _____________.
14. The temperature and time period employed in holder’s method of pasteurisation is _________.
15. An alternative method used to create anaerobiosis in an anaerobic jar is _____________ system.
16. The exponential increase in the number of the bacterial cells occurs in _______________ phase of
the bacterial growth curve.
17. Biological indicator employed in an autoclave is ____________________.
18. Mention any one test for disinfectants _________________________.
19. Sterilisation of operation theatres using formaldehyde gas is referred as __________________.
20. ____________________ is an example for transport medium.
21. ________________________ medium is used to perform antibiotic sensitivity test.
22. _______________________________ is the modified agar diffusion method to detect MIC value.
23. ____________________ is a type of air filter used for removal of at least 99.97% of airborne
particles.
24. ___________________ is a dehydration process to preserve bacteria.
25. The time taken for a bacterium to give rise to two daughter cells is called _______________.
26. The lenses of the endoscopes can be best sterilised using _________________.
27. What is Splauding’s classification?. _____________________________________
28. Southern blot is used to identify ___________________.
29. ______________ is referred as the smallest unit of antigenicity on the surface of an antigen.
30. ___________________ antigens are the same or closely related antigens that are found in
different biological species.
31. Artificial active immunity is achieved by the administration of _______________.
32. The type of antibody produced during secondary immune response is _____________.
33. An example for acute phase protein is ____________________.
34. Humoral immune response is mediated by ______________.
35. An example for an acute phase protein is ________________.
36. MHC stands for _________________.
37. __________________ are the abnormal light chains found in condition of multiple
myeloma.
38. Alternate pathway is otherwise called as ___________ pathway.
39. IL-4 is otherwise called as _________________________________________.
40. In Rheumatoid arthritis autoantibodies are formed against ___________________________.
41. Sub-acute bacterial endocarditis (SABE) is caused by _____________________.
42. Dental caries is caused by ________________________.
43. ______________________ is given intravenously for the treatment of early myocardial
infarction.
44. Name the group B streptococci ____________________________________.
45. Gram positive bacilli with a terminal spore showing a characteristic drumstick appearance is
__________________________.
46. Gram positive lanceolate shaped diplococci ____________________________.
47. Watercan perineum is caused by _______________________.
48. What is Crede’s method of treatment?. ______________________________
49. __________________ shows palisade arrangements of morphology.
50. In blood agar, Clostridium perfringens produces _____________ hemolysis.
51. Scarlet fever is caused by __________________ .
52. Alpha toxin produced by Clostridium perfringens is known as ____________________.
53. Lumpy jaw is caused by ___________________________.
54. Trismus or lock jaw is caused by _____________________________.
55. Antibiotic associated colitis is caused by ___________________________.
56. In litmus milk medium, Cl.perfringens produces _______________ fermentation.
57. In-vitro toxigenicity test for the Corynebacterium is ___________________________.
58. Petechial rashes are caused by ________________________________.
59. Capsule swelling reaction is referred as ______________________ phenomenon.
60. Exfoliative toxin in Staphylococci causes _____________________________________.
61. Dick toxin causes _________________________________ fever.
62. An example for anaerobic streptococci is ________________________________.
63. Name one non-suppurative complications of Streptococcus pyogenes _______________________.
64. Carrom coin appearance of the colonies in Pneumococci is due to the production of
________________.
65. Selective medium for Neisseria is ______________________________________.
66. Gram negative diplococci, with kidney shaped cocci in pairs is _______________________.
67. Griffith typing is done based on __________________.
68. Flesh eating bacteria is referred to _______________________________.
69. Doderlein’s bacilli is _______________________.
70. _______________________ are gram negative spindle shaped bacteria.
71. Gram positive bacilli showing typical bamboo stick appearance is
_________________________.
72. In nutrient agar, staphylococcus produces _________________________ colour pigment.
73. Vibrios shows _____________________ motility.
74. Fibrinolysin of streptococci is known as _____________________________.
75. NGU stands for _________________________________.
76. D-test is used to detect resistance to ___________________________.
77. An example for tetrads _____________________.
78. Cocci in eights is ________________.
79. A Polymicrobial infection of the vagina caused by anaerobes is ___________________________.
80. ___________________________ cells are epithelial cells whose surface is coated by adherent
bacilli in vaginosis.
81. The saccharolytic pigmented Bacteroides species is __________________________________.
82. Flagella can be observed by ________________ staining method.
83. Seitz filters are made up of _____________.
84. _______________ filters are made up of cellulose esters with 0.22µm porosity.
85. The spores of ____________________ is used as the biological indicator for checking the efficacy
of a hot air oven.
86. The mechanism of killing in dry heat method of sterilisation is by __________________.
87. ______________ is a form of genetically inherited anaphylaxis.
88. The specific region on the antibody that binds with an antigen is called ___________.
89. Alternate pathway involves two factors namely _________ & ________.
90. A safe method of destroying infectious materials by complete burning is _____________.
Concept maps on 5 x 5 = 25
1. Moist heat sterilisation.
2. Anaphylaxis.
3. Staphylococci.
4. Corynebacterium diphtheriae.
5. Gas gangrene.