ACTIVE LEARNING TEMPLATE: SYSTEM DISORDER
STUDENT NAME:
DISORDER/DISEASE PROCESS:
Peptic Ulcer Disease (PUD)
REVIEW MODULE CHAPTER:
Gastrointestinal System
Pathophysiology Related to Client Problem:
Peptic Ulcer Disease involves mucosal erosion in the stomach or duodenum due to an imbalance between
protective factors (mucus, bicarbonate, prostaglandins) and aggressive agents (acid, pepsin, H. pylori,
NSAIDs). This can lead to bleeding, perforation, or obstruction if left untreated.
Health Promotion and Disease Prevention:
- Avoid chronic NSAID use unless prescribed
- Quit smoking and limit alcohol
- Manage stress effectively
- Maintain balanced diet and avoid irritating foods
- Test and treat H. pylori when indicated
Risk Factors:
- H. pylori infection
- Long-term NSAID use
- Smoking, alcohol use
- Stress, severe illness
- Zollinger-Ellison syndrome
Expected Findings:
- Burning epigastric pain
- Pain relief with food (duodenal) or worsens after eating (gastric)
- Nausea, bloating
- Hematemesis, melena
Laboratory Tests:
- CBC (check for anemia)
ACTIVE LEARNING TEMPLATE: SYSTEM DISORDER
- H. pylori testing (breath, stool, or serology)
- Stool guaiac test for occult blood
Diagnostic Procedures:
- Upper GI endoscopy (EGD) with biopsy
- Barium swallow if endoscopy is unavailable
Nursing Care:
- Monitor for GI bleeding and perforation
- Administer medications as prescribed
- Encourage lifestyle and dietary changes
- Assess for medication side effects
- Educate on adherence to treatment plan
Therapeutic Procedures:
- Endoscopic hemostasis (cauterization or clipping)
- Surgical intervention (vagotomy, pyloroplasty) for severe or recurrent ulcers
Medications:
1. Omeprazole (Prilosec) - Proton Pump Inhibitor
2. Ranitidine (Zantac) - H2 Receptor Blocker
3. Sucralfate (Carafate) - Mucosal Protectant
4. Amoxicillin (Amoxil) - Antibiotic (H. pylori)
5. Clarithromycin (Biaxin) - Antibiotic (H. pylori)
Client Education:
- Take medications as directed
- Avoid NSAIDs and known triggers
- Quit smoking, reduce stress
- Report signs of bleeding (black stools, vomiting blood)
Interprofessional Care:
- Gastroenterologist: diagnosis and endoscopy
- Dietitian: meal planning
- Pharmacist: medication education and adherence
ACTIVE LEARNING TEMPLATE: SYSTEM DISORDER
- Nurse: education and monitoring
Alterations in Health:
Mucosal ulceration due to acid-pepsin imbalance
Safety Considerations:
- Monitor for hypotension, tachycardia, dizziness (bleeding)
- Ensure proper follow-up after procedures
- Reinforce medication adherence
Complications:
- GI bleeding
- Perforation and peritonitis
- Gastric outlet obstruction
- Risk of malignancy with chronic H. pylori infection