Drug Route Administration Questions

1. Which of the following is a route of drug administration?

A) Metabolism
B) Excretion
C) Oral
D) Distribution

2. The choice of drug administration route does NOT depend on:

A) Drug properties
B) Therapeutic objectives
C) Patient factors
D) Drug metabolism

3. Which route involves administering drugs through the digestive tract?

A) Parenteral
B) Enteral
C) Topical
D) Inhalation

4. Oral, sublingual, and rectal are examples of which route of administration?

A) Parenteral
B) Enteral
C) Topical
D) Inhalation

5. Which of the following is a disadvantage of the oral route?

A) Rapid absorption
B) First-pass metabolism
C) Convenience
D) Patient compliance

6. First-pass metabolism primarily occurs in the:

A) Kidney
B) Lungs
C) Liver
D) Heart

7. Which enteral route allows drugs to bypass first-pass metabolism?

A) Oral
B) Rectal
C) Sublingual
D) Buccal
8. Sublingual administration involves placing the drug:
A) In the rectum
B) Under the tongue
C) On the skin
D) Into a vein

9. Which route is useful for local effects or when the patient is unable to swallow?
A) Oral
B) Sublingual
C) Rectal
D) Intravenous

10. Parenteral routes of administration bypass the:

A) Lungs
B) Liver
C) Digestive tract
D) Kidneys

11. Intravenous (IV) administration involves injecting drugs into:

A) Muscle
B) Skin
C) Vein
D) Spinal fluid

12. Which route provides the most rapid onset of action?

A) Intramuscular
B) Subcutaneous
C) Intravenous
D) Oral

13. Which route is suitable for drugs that are not absorbed orally?
A) Oral
B) Sublingual
C) Intravenous
D) Rectal

14. Which of the following is a disadvantage of IV administration?

A) Irreversible
B) Suitable for large volumes
C) Rapid onset
D) Bypasses first-pass effect

15. Intramuscular (IM) injections are administered into:

 A) Veins
B) Muscles
C) Skin
D) Spinal fluid

16. Which route allows for a moderately rapid onset of action?

A) Intravenous
B) Subcutaneous
C) Intramuscular
D) Oral

17. Subcutaneous (SC) injections are administered into:

A) Muscles
B) Veins
C) Tissue under the skin
D) Spinal fluid

18. Which route provides a slower onset compared to IM?

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Oral

19. Which route is commonly used for insulin administration?

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Oral

20. Intradermal (ID) injections are administered into the:

A) Muscle
B) Vein
C) Dermis of the skin
D) Subcutaneous tissue

21. The route of administration used for tuberculin testing is:

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Intradermal

22. Which route involves injecting drugs directly into the spinal fluid?
A) Intravenous
B) Intrathecal
 C) Intramuscular
D) Subcutaneous

23. Intrathecal administration is used to bypass the:

A) Liver
B) Blood-brain barrier
C) Kidneys
D) Lungs

24. Epidural administration involves injecting drugs into the:

A) Spinal cord
B) Subarachnoid space
C) Epidural space
D) Muscle tissue

25. Which route is commonly used for administering anesthetics during childbirth?
A) Intrathecal
B) Epidural
C) Intravenous
D) Intramuscular

26. Intra-articular injections are administered into:

A) A vein
B) A muscle
C) A joint
D) The skin

27. Which route is used for injecting drugs directly into the bone marrow?
A) Intravenous
B) Intraosseous
C) Intramuscular
D) Subcutaneous

28. Intraosseous administration is useful in:

A) Routine vaccinations
B) Emergency situations
C) Long-term therapy
D) Topical applications

29. Topical administration involves applying drugs to the:

A) Skin or mucous membranes
B) Muscles
C) Veins
D) Spinal fluid
30. Which of the following is an example of topical administration?
A) Inhalation
B) Eye drops
C) Intravenous injection
D) Oral tablet

31. Which of the following is an example of topical administration?

A) Inhalation
B) Eye drops
C) Intravenous injection
D) Oral tablet

32. Transdermal patches are used for:

A) Rapid drug delivery
B) Sustained drug delivery
C) Immediate local effect
D) Bypassing the liver

33. Inhalation involves administering drugs into the:

A) Digestive system
B) Respiratory tract
C) Bloodstream
D) Skin

34. Which route is commonly used for administering drugs in asthma?

A) Oral
B) Intravenous
C) Inhalation
D) Rectal

35. Nebulizers are used to deliver drugs via:

A) Oral route
B) Intravenous route
C) Inhalation route
D) Topical route

36. Which route involves administering drugs directly into the eye?
A) Nasal
B) Ocular
C) Otic
D) Buccal

37. Eye drops are an example of:

 A) Nasal administration
B) Ocular administration
C) Otic administration
D) Oral administration

38. Which route involves administering drugs into the ear?

A) Nasal
B) Ocular
C) Otic
D) Buccal

39. Ear drops are an example of:

A) Nasal administration
B) Ocular administration
C) Otic administration
D) Oral administration

40. Which route involves administering drugs through the nose?

A) Oral
B) Nasal
C) Otic
D) Ocular

41. Nasal sprays are an example of:

A) Oral administration
B) Nasal administration
C) Otic administration
D) Ocular administration

42. Buccal administration involves placing the drug:

A) Under the tongue
B) Between the gum and cheek
C) In the rectum
D) On the skin

43. Which route allows for absorption through the oral mucosa?
A) Oral
B) Sublingual
C) Buccal
D) Rectal

44. Which route is suitable for drugs that are destroyed by gastric acid?
A) Oral
B) Sublingual
 C) Buccal
D) All of the above

45. Which of the following is NOT a parenteral route?

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Oral

46. Parenteral administration generally results in a(n) __ onset of action compared to enteral.
A) Slower
B) Faster
C) More variable
D) Less predictable

47. Which route is associated with the highest risk of infection if not performed correctly?
A) Oral
B) Topical
C) Intravenous
D) Rectal

48. The rate of drug absorption is generally fastest in which route?

A) Oral
B) Subcutaneous
C) Intramuscular
D) Intravenous

49. Which route is subject to the "first-pass effect?"

A) Sublingual
B) Oral
C) Intravenous
D) Inhalation

50. Which route is ideal for delivering drugs directly to the central nervous system?
A) Intramuscular
B) Subcutaneous
C) Intrathecal
D) Oral

51. Which route is commonly used for administering heparin?

A) Oral
B) Intravenous
C) Intramuscular
D) Rectal
52. Which route is suitable for administering depot formulations of drugs?
A) Intravenous
B) Subcutaneous
C) Oral
D) Inhalation

53. Which route is used for allergy testing?

A) Intravenous
B) Intramuscular
C) Intradermal
D) Subcutaneous

54. Which route is used for delivering drugs directly into a joint space?
A) Intravenous
B) Intra-articular
C) Intrathecal
D) Intramuscular

55. Which route is used for rapid fluid and drug administration when IV access is difficult?
A) Subcutaneous
B) Intraosseous
C) Intramuscular
D) Oral

56. Which route is suitable for delivering drugs that are poorly absorbed from the GI tract?
A) Oral
B) Rectal
C) Sublingual
D) Buccal

57. Which route is used for local application to the skin?

A) Intravenous
B) Intramuscular
C) Topical
D) Subcutaneous

58. Which route is used for systemic drug delivery through the skin?
A) Topical
B) Transdermal
C) Intradermal
D) Subcutaneous

59. Which route provides a rapid onset of action for respiratory drugs?
 A) Oral
B) Intravenous
C) Inhalation
D) Subcutaneous

60. Which route is used for administering eye medications?

A) Nasal
B) Ocular
C) Otic
D) Buccal

61. Which route is used for administering ear medications?

A) Nasal
B) Ocular
C) Otic
D) Buccal

62. Which route is used for administering nasal decongestants?

A) Oral
B) Nasal
C) Otic
D) Ocular

63. Which route is suitable for rapid absorption of lipid-soluble drugs into the bloodstream via
the oral mucosa?
A) Oral
B) Sublingual
C) Buccal
D) Rectal

64. Which of the following is a disadvantage of the rectal route?

A) First-pass metabolism
B) Patient acceptance
C) Rapid absorption
D) Bypasses liver metabolism

65. Which route is most likely to be affected by food interactions?

A) Intravenous
B) Oral
C) Subcutaneous
D) Inhalation

66. Which route provides the most predictable bioavailability?

A) Oral
 B) Intramuscular
C) Intravenous
D) Subcutaneous

67. Which route is associated with potential pain or discomfort at the injection site?
A) Oral
B) Intravenous
C) Intramuscular
D) Sublingual

68. Which route is suitable for self-administration by patients?

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) All of the above

69. Which route is used for administering local anesthetics?

A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Topical

70. Which route is designed to provide a sustained release of medication over a prolonged
period?
A) Intravenous bolus
B) Oral tablet
C) Transdermal patch
D) Sublingual tablet

71. Which route is commonly used for delivering bronchodilators?

A) Oral
B) Intravenous
C) Inhalation
D) Rectal

72. Which route is used for administering drugs to treat eye infections?
A) Nasal
B) Ocular
C) Otic
D) Buccal

73. Which route is used for administering drugs to treat ear infections?
A) Nasal
B) Ocular
 C) Otic
D) Buccal

74. Which route can be used for both local and systemic drug effects?
A) Oral
B) Topical
C) Intravenous
D) Intramuscular

75. Which of the following is a characteristic of the sublingual route?

A) Subject to first-pass metabolism
B) Slow absorption
C) Rich blood supply for rapid absorption
D) Suitable for large drug volumes

76. Which route is most convenient for self-administration?

A) Intravenous
B) Intramuscular
C) Oral
D) Intrathecal

77. Which route is associated with the risk of nerve damage if not administered correctly?
A) Intravenous
B) Intramuscular
C) Subcutaneous
D) Oral

78. Which route is essential for drugs that are unstable in the gastrointestinal tract?
A) Oral
B) Rectal
C) Parenteral
D) Topical

79. Which route allows for precise control over the drug dosage?
A) Oral
B) Intravenous infusion
C) Intramuscular
D) Rectal

80. Which route is used for delivering drugs that need to cross the blood-brain barrier?
A) Oral
B) Intravenous
C) Intrathecal
D) Subcutaneous
81. Which route is suitable for administering drugs to unconscious patients?
A) Oral
B) Sublingual
C) Rectal
D) Buccal

82. Which route is commonly used for nicotine replacement therapy?

A) Oral
B) Intravenous
C) Transdermal
D) Inhalation

83. Which route is used for administering general anesthetics?

A) Oral
B) Intravenous
C) Topical
D) Rectal

84. Which route is suitable for drugs with poor oral bioavailability?
A) Oral
B) Parenteral
C) Topical
D) Sublingual

85. Which route minimizes fluctuations in drug plasma concentrations?

A) Oral
B) Intravenous bolus
C) Transdermal
D) Subcutaneous injection

86. Which route is associated with the risk of embolism?

A) Intramuscular
B) Subcutaneous
C) Intravenous
D) Intradermal

87. Which route is used for delivering drugs directly to the lungs?
A) Oral
B) Nasal
C) Inhalation
D) Ocular

88. Which route is used for administering drugs for local effect on the skin?
 A) Transdermal
B) Topical
C) Subcutaneous
D) Intramuscular

89. Which route is used for systemic effect through skin absorption?
A) Topical
B) Transdermal
C) Intradermal
D) Subcutaneous

90. Which route is used to administer insulin?

A) Oral
B) Intramuscular
C) Subcutaneous
D) Intravenous

91. Which route allows for rapid absorption and quick onset of drug action?
A) Oral
B) Intramuscular
C) Intravenous
D) Subcutaneous

92. Which route is suitable for administering large volumes of fluids?

A) Subcutaneous
B) Intramuscular
C) Intravenous
D) Intradermal

93. Which route is not suitable for oily or irritating substances?

A) Intramuscular
B) Subcutaneous
C) Intravenous
D) Oral

94. Which route can be affected by the patient's swallowing ability?

A) Oral
B) Sublingual
C) Buccal
D) Rectal

95. Which route is useful for patients experiencing nausea or vomiting?

A) Oral
B) Sublingual
 C) Rectal
D) Buccal

96. Which route is used for delivering some vaccines?

A) Oral
B) Intravenous
C) Intramuscular
D) All of the above

97. Which route can be influenced by the patient's skin condition?

A) Oral
B) Intravenous
C) Topical
D) Intramuscular

98. Which route is used for administering drugs in aerosol form?

A) Oral
B) Nasal
C) Inhalation
D) Ocular

99. Which route can provide a localized effect without systemic absorption?
A) Oral
B) Intravenous
C) Topical
D) Subcutaneous

100. The choice of administration route is crucial for:

A) Achieving the desired therapeutic effect
B) Minimizing adverse effects
C) Optimizing drug delivery
D) All of the above

Answers:

Questions 1-25

1. c) Oral
2. d) Drug metabolism
3. b) Enteral
4. b) Enteral
5. b) First-pass metabolism
6. c) Liver
7. c) Sublingual
8. b) Under the tongue
9. c) Rectal
10. c) Digestive tract
11. c) Vein
12. c) Intravenous
13. c) Intravenous
14. a) Irreversible
15. b) Muscles
16. c) Intramuscular
17. c) Tissue under the skin
18. c) Subcutaneous
19. c) Subcutaneous
20. c) Dermis of the skin
21. d) Intradermal
22. b) Intrathecal
23. b) Blood-brain barrier
24. c) Epidural space
25. b) Epidural

Questions 26-50

26. c) A joint
27. b) Intraosseous
28. b) Emergency situations
29. a) Skin or mucous membranes
30. b) Eye drops
31. b) Sustained drug delivery
32. b) Respiratory tract
33. c) Inhalation
34. c) Inhalation route
35. b) Ocular
36. b) Ocular administration
37. c) Otic
38. c) Otic administration
39. b) Nasal
40. b) Nasal administration
41. b) Between the gum and cheek
42. c) Buccal
43. d) All of the above
44. b) Intestine
45. d) Oral
46. b) Faster
47. c) Intravenous
48. d) Intravenous
49. b) Oral
50. c) Intrathecal

Questions 51-75

51. b) Intravenous
52. b) Subcutaneous
53. c) Intradermal
54. b) Intra-articular
55. b) Intraosseous
56. b) Rectal
57. c) Topical
58. b) Transdermal
59. c) Inhalation
60. b) Ocular
61. c) Otic
62. b) Nasal
63. b) Sublingual or c) Buccal
64. b) Patient acceptance
65. b) Oral
66. c) Intravenous
67. b) Intramuscular
68. c) Subcutaneous
69. d) Topical
70. c) Transdermal patch
71. c) Inhalation
72. b) Ocular
73. c) Otic
74. b) Topical
75. c) Rich blood supply for rapid absorption

Questions 76-100

76. c) Oral
77. c) Intramuscular
78. c) Parenteral
79. b) Intravenous infusion
80. c) Intrathecal
81. c) Rectal
82. c) Transdermal
83. b) Intravenous
84. b) Parenteral
85. c) Transdermal
86. c) Intravenous
87. c) Inhalation
88. b) Topical
89. b) Transdermal
90. c) Subcutaneous
91. c) Intravenous
92. c) Intravenous
93. c) Intravenous
94. a) Oral
95. c) Rectal
96. d) All of the above
97. c) Topical
98. c) Inhalation
99. c) Topical
100. d) All of the above