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Paed Doses New Compile - 1

The document provides a comprehensive guide on pediatric dosages for various antibiotics and gastrointestinal drugs, including their formulations, dosages, and indications. It also covers respiratory medications, analgesics, antifungals, and topical ointments, detailing appropriate usage for children of different ages. This resource serves as a reference for healthcare professionals prescribing medications to pediatric patients.

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0% found this document useful (0 votes)
2K views38 pages

Paed Doses New Compile - 1

The document provides a comprehensive guide on pediatric dosages for various antibiotics and gastrointestinal drugs, including their formulations, dosages, and indications. It also covers respiratory medications, analgesics, antifungals, and topical ointments, detailing appropriate usage for children of different ages. This resource serves as a reference for healthcare professionals prescribing medications to pediatric patients.

Uploaded by

savfbensg
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 38

By Dr.Ahmed Naeem PM-1 ----- Page No.

Pediatric Dosages - Antibiotics


Drugs Dosage Formulations Available Indications/CI
Syp.Amoxil 50mg/kg/day 125mg/5ml URTI, Dental Abscess, Skin/Skin
(Amoxicillin) BD/TDS 250mg/5ml structure infections, ENT
Max 1g/Day infections(OM)
st
Syp. Calamox/Augmentin 30-50mg/kg/day 156mg/5ml 1 line URTI/GABHS
(Amoxil+clavulinic acid) BD/TDS 312mg/5ml Skin
457mg/5ml ENT
625mg/5ml Dental Abscess-1st Line
Syp. Azit/Zeecin/Azomax 12-15mg/kg/day 200mg/5ml 2nd line URTI
(Azithromycin) OD Atypical organisms causing LRTI
Enteric Dose Shigella, campylobacter ,severe
20mg/kg/day dysentery, enteric fever
Endocarditis prophylaxis
Syp Klaricid/Rithmo 15mg/kg/day 125mg/5m 2nd line URTI
(clarithromycin) BD 250mg/5ml Atypical LRTI/ H.pylori
Max 1g/Day cat scratch, Ear(OM)
2nd line endocarditis
Syp. Novidat/orcip 15-30mg/kg/day 125mg/5ml 1st line Dysentry
(ciprofloxacin) BD 250mg/5ml 2nd line UTI
Severe dysentery, EPEC,ETEC,EIEC
STDs
Syp. Flagyl 20-30mg/kg/day 100mg/5ml ABx induced diarrhea, C. Difficile
(metronidazole) BD/TDS 200mg/5ml infection, E.Histolytica,
Giardia,H.pylori,vaginosis
Syp. Septran/ Septran DS 50-60mg/kg/day >2 Months Dysentery, UTI 3-5days,
(TMP-SMX) BD 200/40mg/5ml
400/80mg/5ml
Syp. Nitazide/Diatazox 100mg-BD 100mg/5ml Smelly Diarrhea, Anti-infective (Covers
(Nitazoxanide) (1-3years) Most of organisms causing diarrhea in
200mg-BD children including rota)
(3-11Years)
Syp. Cefspan/cefiget/karicef 10mg/kg/day 100mg/5ml Otitis Media, Strep throat, LRTI, UTI,
/Mixel 200mg/5ml Gonorrohea, Lyme, Typhoid, URTI,
(Cefixime) 20mg/kg/day 400mg/5ml E.coli Dysentry
3rd gen Cephalo. (enteric dose)
BD

Syp. Velosef 25-50mg/kg/day 125mg/5ml GABHS, OM, Skin/Structure


(cephradine)
1st gen cephalo.
Syp. Cefalor 20-40mg/kg/day 125mg/5ml URTI,LRTII,UTI,skin
(cefaclor) TDS 250mg/5ml Rarely used due to serum sickness like
nd
2 Gen.Cephalo Max 2g/24hour symptoms in children
Syp. Dalacin – C 10- 75mg/5ml Acne vulgaris, dental infection 2nd line,
(Clindamycin) 20mg/kg/6hourly Capsule 150mg/cap Pencillin allergic pts.
TDS Step.staph.pneumococci
Syp. Zinnat 20-30mg/kg/day 125mg/5ml URTI,LRTII,UTI,AOM
(Cefuroxime) BD MDR typhoid,CAP
2nd Gen Cephalo
Syp. Orelox 10mg/kg/day 40mg/5ml URTI,LRTII,UTI,AOM
(cefpodxime) 6months-40mgxBD Sinusitis,CAP
3rd Gen Cephalo. 3-8Years-80mgxBD
>9Year-100mgxBD
By Dr.Ahmed Naeem PM-1 ----- Page No. 2

GI DRUGS
Drugs Dosage Formulations Indications/contraindications
Sachet Enflor/Biflor/Gut <1 Year ½ Sachet OD Treatment duration: Better in Antibiotic
Care >1 Year 1 Sachet OD 3 Days induced/associated
(Yeast Based Antibiotic) (in milk/water) diarrhea/C.difficle induced

Enterogermina/Sachet <6 Years 1 Vial OD Use Probiotics 2-3 Better in Acute


PrePro GG/Gut Care >6 Years 1-2 Vials OD hours after Diarrhea/Gastroenteritis
Sachet Imutec (in milk/water) antibiotic intake
(Bacteria Based Probiotic)

Syp. Bonnisan <1 Month ½ Tbsp OD Treatment duration: infantile colic, diarrhea, abdominal
(Herbal) 1-6 Months 1 Tbsp OD 5-7 Days pain and dyspepsia
>6 Months 2 Tbsp OD
Syp. Septillin <1 Month ½ Tbsp OD Treatment duration: immunomodulatory, antioxidant,
(Herbal immunity booster) 1-6 Months 1 Tbsp OD 5-7 Days anti-inflammatory and
>6 Months 2 Tbsp OD antimicrobial
Sachet Doctile/Smecta <1 Year ½ Sachet BD Treatment duration: natural adsorbent clay
(dioctahedral smectite) >1 Year 1 Sachet BD 3 Days adsorb viruses, bacteria, and
(in milk/water with ORS bacterial toxin
therapy)
Syp. Gravinate 0.5-1mg/kg/dose 12.5mg/4ml Children > 2 Years
(dimenhydrinate) TDS Nausea, vomiting, motion sickness

Tab. Onset/Zofran 0.2-0.3 mg/kg/dose 8mg/tablet Acute gastroenteritis


(ondasetron) BD-TDS /Vomiting 1st line

Syp. Spasler – P >6 Years old 5mg/5ml Abdominal Pain


(Hyoscine butylbromide) 0.2-0.4mg/kg

Nospa >4 Years Age 40mg/tablet Recurrent Abdominal Pain


(Drotaverine) 20-40mg
TDS

EZ-Colic Drops Children < 1 Year TDS/ QDS Colic


Pasmolex DROPS 5 Drops Before Breast
Infacol Drops Feeding
Colorest Drops (1 Drop per Kg)
(Herbal)

Colic- rule of 3- A baby that cries for three or more hours per day, at least three times a week, in the first three months
of life without any clear cause

Unilact Drops/Colibid Children < 1 Year transient lactase Colic/Milk intolerance


(Lactase Enzyme Drops) 5 Drops Before Breast intolerance Add to Milk bottle 10 minutes
Feeding before feed

Castor Oil 1tbsp/OD Natural Laxative Constipation


(laxative)
By Dr.Ahmed Naeem PM-1 ----- Page No. 3

Syp. Vermox 100mg 100mg/5ml Pica,ascariasis, pinworm disease,


(Mebendazole) BD hookworm infections, guinea
3 Days worm infections, hydatid
disease,giardia
Syp. Zentel 200mg BD 200mg/5ml giardiasis, trichuriasis, filariasis,
(Albendazole) 400mg OD hydatid disease, pinworm
3 days disease,ascariasis,
40mg/kg/day
Syp. Peptinil 4-10ml/kg/day 75mg/5ml h.pylori
(Ranitidine)

Syp. Famotidine 0.5-1mg/kg/day 10mg/5ml h.pylori


>6years
20mg/day
Syp. Duphalac/Neolac 1Tbsp x BD Constipation
(Lactulose)
Syp. Epitize 1Tbsp Appetite Stimulants
(herbal) BD
Syp. Trimetabol Syp >6 years
(synthetic)
Syp.Cestonil Adults
(pizotifen+Vit.B)
Syp. Mosegor
(pizotifen)
Syp.Tres Orix >12 Months 20mg/day
(Fe + Appetite Stimulant) <12 Monts 10mg/day

Syp. Osiris/Zincat/DiaZinc <6 months – 2.5ml OD 20mg/5ml URTI/LRTI


(zinc sulphate) >6months – 5mlOD 10-14Days Diarrhoea/Vomiting
Syp. Mucaine >6 Years Antacids
1tbsp x BD
Syp Motilium <12 years but >15kg 5mg/5ml Gastroparesis, Nausea, Vomiting
(Domeperidone) 30mg x bd
>12 Years - 60mg x bd
Sachet Risek Insta 40mg/1100mg OD x 7 Days
(Omeprazole + Na Bicarb)
Skilax Drops 20 Drops x H/S 7.5mg/5ml Constipation
>4 Years old
Glycerine Suppository 1 x PR Constipation
By Dr.Ahmed Naeem PM-1 ----- Page No. 4

Respiratory/Antihistamines
Drugs Dosage Formulations/Duration I / CI
Syp. Prospan Children 1-6 Years 5 -7 Days Cough/Cold
Syp. Hylixia 2.5ml x BD
Syp. Dr. Koff Children >6 Years
Syp. Dr.FLU 5ml x BD
Syp. Kroff
(Herbal)
Syp. Kestine >6 years old 5mg/5ml allergic rhinitis and chronic
(Ebastine) 5mg/day OD idiopathic urticaria.
Syp. Jardin D >6months -2 years 0.5mg/ml allergic rhinitis and nasal
(desloratidine) 1mg/day congestion
2 years upto 5 mg/day
Syp. Osiris/Zincat/DiaZinc <6 months – 2.5ml OD 20mg/5ml URTI/LRTI
(zinc sulphate) >6months – 5mlOD 10-14Days Diarrhoea/Vomiting
Syp. Sedil 2.5-5mg BD 5mg/5ml Allergy, Runny nose,
(cetirizine) >6 months old sneezing

Syp. Neosedil 2.5mg BD -5mg OD 5mg/5ml Allergy, Runny nose,


(levocetrizine) >6 months old sneezing

Syp. Britanyl 0.05 – 0.15mg/kg x 0.3mg/5ml Mucolytic


8hourly

Xynosine Nasal Drops 1 Drop B/L x TDS 15ml Drops/inhaler Nasal Congestion
Drops Xlomet >6 years old Ocular Congestion
Spray Xlomet
(Xylometazoline)
Syp. Acefyl 10mg/kg/dose x TDS 125mg/5ml Bronchitis/ Bronchial
(Acefylline) >3 Months Age Asthma/Cough with
(Xanthine Class Stimulator) Sputum
Montika/Freehale 6 months – 5 years Sachet 5mg Asthma
(Montelukast) 4mg x PO x H/S Chewable Tablet 5mg/4mg
6 – 14 Years Tablet 10mg
5mg x PO x H/S
>15 Years
10mg x PO x H/S

Syp. Combinol Juior >6 Years Cough Suppression


Syp. Coldrex 1TSF TDS
By Dr.Ahmed Naeem PM-1 ----- Page No. 5

Analgesics / Antipyretics
Drugs Dosage Formulations I / CI
Drops Panadol 15mg/kg/dose 80mg/2.5ml Fever, Mild Pain
(4-6Hourly) (1 Dropper = 0.8ml)
Syp. Panadol 160mg/5ml
Syp. Calpol 120mg/5ml
Syp. Calpol 6+ 250mg/5ml
(Paracetamol)
Syp.Brufen 10-15mg/kg/dose 100mg/5ml Fever/mild pain
Syp. Brufen DS (4-6Hourly) 200mg/5ml
(Ibuprofen)
Syp. Tercica 10mg/kg/dose 100mg/5ml Fever/mild pain
(Dexibuprofen)
Ketorolac 0.5mg/kg/dose 2-16 Years 3-5 Days Max
4-6 hourly
Tab. Aspirin >16 Years 10-15mg/kg/dose
80mg/kg/day - Kawasaks

Tab. Sumatriptan 25-50mg / Day 25mg/50mg/100mg Migraine

Anti-fungals
Drugs dosage Formulations I / CI
Syp. Diflucan 12mg/kg/day 50mg/5ml Fungal infection
(Fluconazole) Loading=25mg/kg Capsule.100mg,200mg
Nilstat Drops 1 lac units x 8hourly 1 lac IU/ml Oral candidiasis
(Nystatin) (5-7 Days) (20 drops)

Cream Dermosporin, Apply 8 hourly Topical fungal infections


Dermosporin-B
(Clotrimazole)
Cream Daktrin Apply 8 hourly Topical fungal infections
(Miconazole)
Cream Travocort Apply 8 hourly Topical fungal infections
(isoconazole nitrate,
diflucortolone valerate)
Amphotericin B 0.5-1mg/kg/day
OD
By Dr.Ahmed Naeem PM-1 ----- Page No. 6

Topical Ointments

Drugs dosage Formulatons I / ci


Cream Hydrazole Cream Betacin Plus Cream Betnovate N Cream Polyfax

(Hydrocortisone + (Nystatin + neomycin + (Neomycin + (Bacitracin, Polymyxin-B)


clotrimazole) betamethasone) Betamethasone) Cream Polyfax Plus
Cream Aquazole *Lignocaine
Cream Rashnil Cream Kenacomb Lotion Scabion Lotion Lotrix
(nystatin, (lindane + sulphur) (permethrin)
(Benzylkonium+Zinc Oxide) gramicidin,neomycin, >2 Years >2months
triamcinolone)
Tab. Ivermectin Cream Provate-G
200 mcg/kg Single Dose (betamethasone,Gentamicin)

Multivitamins
Mutliviitamins Vitamin B complex Vitamin E Vitamin – D
Drops. Vidaylin + Iron ORA – E Ora- A
Syp. Vidalyin L Syrup Iberet 500 1 Drop x OD D- Max
Syp. Vidalyn M Syp. Lederplex 1 Drop x OD
Tab. Vidalyin T Syp. Maltofer 6lac IU x I/M
Syp. Multibionta M Iron = 3-6mg/kg/day
1 year ¼ dropper IM = 100mcg/24hr for 10
1-2 years ½ dropper Days
>2 years 1 dropper
OD
Vitamin A Vitamin C Calcium
ORA – A Drops Cecon 100mg/ml Qalsan Junior
A-Max 1-3years 15mg Sachet Calcee 500
Stat Dose- 4-8 years 25mg Syp. Calcium P
<6months - 80,000 9-13 years 45mg 1 TSF x OD
6months – 1 year 1 lac (100-300mg/24hrs) 700-1300mg/day
>1 years - 2 lac IU OD for 2 weeks
Maintenance
1 Drop x OD = 2100 IU
By Dr.Ahmed Naeem PM-1 ----- Page No. 7

EYE
Drugs Dosage Formulations/Duration Indications
Drops Histazolin 1 Drop x TDS 2 weeks Viral Conjunctivitis
(na chromoglycoate,
tetrhyrdrozoline)

Drops Rocip 1 Drop x TDS 14 days Bacterial Conjunctivitis


(ciprofloxacin)
Drops Tobrex 1 Drop x TDS 5 Days
(Tobramycin)
Drops Nebra 1 Drop x TDS 5 Days
(Tobramycin)
Drops Xepat 1 Drop x TDS Allergic conjunctivitis
(oloptadine)

Drops FML 1 drop x TDS Corticosteroid


(fluorometholone)

Drops Fendic S 1 drop x TDS Pain Mx


(Diclofenac Na)
Drops Torolac
(Ketorolac)
Drops Moxicin 1 drop x TDS 5-7 Days Bacterial Conjunctivitis

EAR
Drugs Dosage/Duration Indication
Drops Otosporin 2+2+2+2
(Hydrocortisone, polymyxn b,
neomycin)
Drops Otocain Drops Ofloxacin Drops Cipotic
(Lignocaine + Polymyxin B) (Ofloxacin) Drops Cipocain
(Ciporfloxacin)
Drops Otogen Drops Waxaid
(Gentamicin) (Glycerine)
By Dr.Ahmed Naeem PM-1 ----- Page No. 8

ANTI-MALARIALS
Syp. Arceva 15/90mg/5ml 1.2mg/kg
Syp.Arceva D/S 30/180mg/5ml Arceva D/S
(Artemether + Lumefantrine) OD x 3Days 1-10kg – 5ml
11-15kg-8.5ml
15-20kg-12ml
Neb. Atem <6month 0.2cc +2cc N/S
6-12months 0.5cc (Neb with Hypertonic saline
Neb. Salbutamol >1year 1cc in Brochiolitis)
(>2months)
Neb. Adrenaline 3 Vials x stat
For Croup

Neb. 3% Hypertonic Bronchiolitis

MISC.

Inj. Glucagon 0.5mg/dose Antidote for B-Blockers/CCBs


Low BSR

Rivotril Drops
(clonazepam)
Inj. Dormicum 1ug/kg/min
(Midazolam)
Tab. Amlodipine 0.1mg/kg/dose
Max 5mg
Inj. Streptomycin 30mg/kg/day
OD x IM
Tab. Viagra P. HTN

Syp. Citralka 1 TSF x BD UTI


Syp. Citrosoda >8 Years
Tab. Tofranil 6-8 Years 25mg x H/S Nocturnal Enuresis
8-12 Years 50mg
By Dr.Ahmed Naeem PM-1 ----- Page No. 9

IV/IM Drugs Dosage Formulations


Inj. Diazepam 0.2mg/kg/dose Max 10mg/dose
>5 years
(IV) Max 5mg/dose
<5 Years
Inj. Gravinate (IM) 0.5-1mg/kg/dose
Inj. Onset 0.1-0.2mg/kg/dose
IV diluted in 20cc N/S
(IM/IV)
Inj. Avil 0.1mg/kg/dose
Inj. Solu-cortef/Hycortisone 10mg/kg/dose
Inj. Dexamethasone 0.5-2mg/kg/day 6 doses, 8h x IV
Inj. Zantac 2mg/kg/dose
Inj. Phenytoin 15mg/kg/dose = Loading,
5-10 mg/kg x BD = Maintenance
Inj. Adrenaline 0.1mg/kg/dose Max. 1mg
S/C , I/V
(1 in 10,000)
Inj. Dicloran 0.75mg/kg/dose IM
Inj. Nospa 0.5-1mg/kg/day IM
Inj. Omeprazole 1mg – 3mg/kg/dose <20kg wt
10mg/10kg/day >20kg wt
>2 Years
Inj. Lasix 1mg/kg/dose
Inj. Aclova >12 years 14-21 Days
30mg/kg/day 8 hourly
3M-12 Years
60mg/kg/day 8 hourly
Inj. Lerace 10mg/kg/day 40mg/kg/day Max
Inj. Dopa/Dobutamine 5-20mcg
(0.0005-0.20mg/kg)
Inj. Flagyl 30mg/kg/day
Whole Blood/Packed Cells 10ml/kg/transfusion
*Mid Transfuion Lasix in children
FFPs/Platelets
Inj. Paracetamol 1ml/kg/dose
Inj. Mannitol 0.7ml/kg/dose 0.5-1 Stat
0.25-0.5kg/dose
maintenance
Inj. Naloxone 0.1mg/kg Every 15 minutes
Repeated 3-4 times
Tab. Acetazolamide 5mg/kg/dose x OD
Human Albumin 20 % 1g/kg/dose in N/S over 2-4 Hours
Inj. Ca-Gluconate 200-500mg/kg/day
6hourly
By Dr.Ahmed Naeem PM-1 ----- Page No. 10

IV/IM ANTIBIOTICS
Drugs Dosage Remarks
Inj. Cefotaxime 100mg/kg/day x BD Max 12gm/day
st
1 Line 200mg/kg/day (meningitic)
Inj. Amikacin 15mg/kg/day x OD <7 Days
1st BD > 7 Days
Inj. Meronem 60mg/kg/day x TDS
nd
2 100mg/kg/day(Meningitic)
Inj. Vancomycin 45mg/kg/day x TDS
2nd 60mg/kg/day(Meningitic)
Inj. Tanzo 90mg/kg/dose x TDS
3rd
Inj. Ciprofloxacin 15mg/kg/day x BD
3rd
Inj. Linezolid 10mg/kg/dose x TDS
4th
Inj. Ampicillin 100mg/kg/day x BD
4th
Inj. Cefipirome 100mg/kg/day x BD
4th
Inj. Ceftriaxone 50mg/kg/day If >1g divided in BD
>3 months Age Pneumonia
1st line 75mg/kg/day
Enteric Fever
100mg/kg/day
Meningitis
Inj. Aminophylline Stat-6mg/kg/dose
<34 Weeks 3mg/kg/day x BD
Inj. Leflox 10mg/kg/dose
<5 Years 12 hourly
>5 Years -24 Hourly
Inj Aminovil 15mg/kg/day OD
If NPO start on 3rd day
Inj. Flagyl 30mg/kg/day x TDS
By Dr.Ahmed Naeem PM-1 ----- Page No. 11

FLUIDS
Inj. R/L Neonatal Fluid Req.
<1 year 30ml/kg – 1 hour
70ml/kg – 5 Hours D1 10% D/W
D2 10 % D/W + N/5
>1 Year 30ml/kg – 30 minutes
70ml/kg – 2.5 Hours D3 10 % D/W + N/5
+ 1cc KCL + 2cc Ca. Gluconate
Inj. N/S or Paedes Soln.
TERM Preterm
<10kg Wt. – 100ml/kg/day
D1 60ml 80ml
10-20Kg Wt. – 1000ml + 50ml/every kg over D2 80ml 100ml
10/day D3 100ml 120ml
D4 120ml/kg/day 140ml/kg/day
>20kg Wt - 1500ml + 20ml/every kg over
20/day D5 140ml/kg/day 160ml/kg/day
D6 160ml/kg/day 160ml/kg/day
2cc KCL/100ml
Max. Fluid in neonate upto 160ml/kg/day, Add 20ml/kg/day if on phototherapy or persistent vomiting or
persistent diarrhea, give 30% fluids if phototherapy needed and baby on phototherapy

 ORS therapy only in > 4 months old


 Age <1Year / <10Kg Fluid of Choice = N/5 + 5% D/W
 Age >1Year / >10Kg Fluid of Choice = N/2 + 5% D/W
 Low Osmolar Sachet for Chronic Diarrhoea/<4 Months Age
GENERAL PEDIATRICS

Drug Dose Frequency


ACD plus drops 1-2 years: 1 drop OD || 3-12 years: 2 drop OD OD 1 drop contains daily requirement dose of vitamin A and D
Acetazolamide 30 mg/kg/day TDS
Acyclovir 10 mg/kg/dose TDS Syp Acylex 200mg/5ml
in 1 ml (20 Drops) Vit A 1500 IU, Vit D 600 IU, Vitamin E 15 IU, Vitamin K 40 mcg, Zinc
ADEK Z drops 0-6 months: 10 drops (0.5ml) || >6 months: 20 drops (1 ml) OD
5 mcg
Albendazole 400 mg/dose (for >2 years only) Stat dose Syp Zentel 100 mg/5ml, Tab Zentel 200 mg
Amikacin 15 mg/kg/day BD
Amoxicillin (Post splenectomy) 10 mg/kg/day || max 250mg/dose BD
Amoxil 20-50mg/kg/day (mild infection) 50-90mg/kg/day (severe infections) TDS Syrup Amoxil 125mg/5ml, Syp Amoxil Forte 250mg/5ml
Ampicillin 50-100 mg/kg/dose TDS

Arceva Next sheet OD for 3 days

Aspirin (Low dose - prophylaxis) 3-5 mg/kg/day OD Tab ascard 75mg


Atem (Ipratropium) 125 - 250 mcg/dose TDS Atem nebs 500mcg/vial, Ipneb solution 250mcg/ml (1 ml=35 drops)
Augmentin 50 mg/kg/day TDS Syp Augmentin 156 mg/5ml, Augmentin DS 312mg/5ml, Augmentin BD 457 mg/5ml
Avil IV (Chlorpheniramine) 0.5mg/kg IV stat
Avil Oral (Chlorophenol amine) <10 kg: 1/2 tsf || 10 kg: 1 tsf || >12 kg 2 tsf OD Syp Avil 15mg/5ml
Azithromycin (Azomax) 10 mg/kg/day OD Syp 200 mg/5ml
Azithromycin (XDR Enteric) 20 mg/kg/day
Baclofen 10 - 15 mg/kg/day TDS
Bonnisan Syrup 0-1m: 2.5 ml TDS, 1-6m: 5 ml TDS, 6m-3 yrs: 10ml TDS
Calcium IV (Replacement) 2 ml/kg/dose QID
Calcium Oral (SAM) 80 mg/kg/day BD Syp Cal-P 210 mg/5ml
Captopril 0.3 - 0.5 mg/kg/day BD, TDS Tab Capril 12.5 mg, 25mg
Cefaclor 20 - 40 mg/kg/day TDS Syp Ceclor 125mg/5ml, 250mg/5ml. Ceclor drops 125mg/1ml (1 dropper = 1 ml)
Cefixime 10 mg/kg/day OD Syp Cefam 100 mg/5ml, 200 mg/5ml
Cefixime (Enteric) 20 mg/kg/day OD Syp Cefam 100 mg/5ml, 200 mg/5ml
Cefixime (UTI) 20 mg/kg/day BD x 10 days Syp Cefam 100 mg/5ml, 200 mg/5ml
Cefotaxime (Age more than 7 days) 150 mg/kg/day TDS
Cefotaxime (Meningitic) 200 mg/kg/day BD/TDS TDS dose if age greater than 7 days
Cefotaxime (neonate less than 7 days) 100 mg/kg/day BD
Cefpodoxime (Orelox) 8-10 mg/kg/day BD Syrup Orelox 40mg/5ml
Ceftriaxone 50 mg/kg/day BD (OD dose in ER)
Ceftriaxone (Enteric) 75 mg/kg/day BD
Ceftriaxone (Meningitic) 100 mg/kg/day BD
Ciprofloxacin 15mg/kg/day BD Syp Novidate 125 mg/5ml, Syp Novidate 250 mg/5ml
Ciprofloxacin (Cholera) 30mg/kg/day BD Syp Novidate 125 mg/5ml, Syp Novidate 250 mg/5ml
Ciprofloxacin IV 15 mg/kg/day BD
Ciprofloxacin Oral 20 - 30 mg/kg/day BD
Clenil (Baclomethasone + Salbutamol) 0.5 vial/dose BD Clenil nebs 800mcg+1600mcg/vial
Clindamycin 20 mg/kg/day
Colic Drops 0-4m: 5-10 drops TDS or QID, >4m: 10-20 drops TDS or QID TDS or QID
Debritone (Loading) 20 mg/kg Syp Debritone 20 mg/5ml
Debritone (Maintenance) 3 - 5 mg/kg/day BD Syp Debritone 20 mg/5ml
Deltacortil (Prednisolone)Nephrotic syndrome Starting 60 mg/m2/day (2 mg/kg/day) Tab deltacortil = 5mg, Syp Sterone 15 mg/5ml, Syp Rapicort 15mg/5ml
Deltacortil (Prednisone) Asthama 1 - 2 mg/kg/day for 7 days Tab deltacortil = 5mg, Syp Sterone 15 mg/5ml
Dexa (Decadron) Anti-inflammatory 0.3 mg/kg/day BD, TDS
Dexa (Decadron) Cerebral Edema Loading 1 - 2 mg/kg/dose
Dexa (Decadron) Cerebral Edema Maintenance 0.2 - 0.5 mg/kg/day QID
Dexa (Decadron) Meningitis 0.6 mg/kg stat || 0.6mg/kg/day maintenance QID for 6 days
Dexa (Decadron) Pre-Extubation 0.25 - 0.5 mg/kg/day TDS
Dexa (Decadron) Stat dose 0.6 mg/kg/stat dose
Diatazox (Nitazoxanide) 1-3 years: 5ml BD || 4-11years: 10ml BD || 7.5mg/kg/day BD for 3 days
Dormicum/midazolam (stat dose) 0.1-0.5 mg/kg/dose
Dormicum infusion 1-18 mcg/kg/min
Domperidone (Vomilux) 0.5mg/kg/dose TDS Syp vomilux 1mg/1ml, Syp Domel 5mg/5ml
Doxofylline (Unifylline) <12: 6-9 mg/kg/dose BD, >12: 200 mg BD or TDS BD/TDS Syrup Unifylline 100mg/5ml
Doxycycline (vibramycin) (Cholera) 4-6 mg/kg/ dose Stat Capsule doxycycline 100mg
Entamizole (Diloxanide furoate, Metronidazole) 10 mg/kg/dose TDS - 5 to 7 days 250mg/200mg/10ml
Epival (Loading, IV) 20 - 30 mg/kg Stat dose
Epival (Maintenance) 10 - 60 mg/kg/day BD Syp Epival 250 mg/5ml
Falgan 10-15 mg/kg (1.0-1.5 ml/kg) TDS/QID
Famotidine (Polypep) Peptic Ulcer 0.5-1.0 mg/kg HS, 0.5mg/kg BD HS or BD upto 8 weeks Syrup Polypep 10mg/5ml, Syrup Peptiban 10mg/5ml, Max 40mg/day
<3m: 0.5-1.0mg/kg OD || 3-12m: 0.5-1.0mg/kg BD, || 1-17y: 0.5mg/kg
Famotidine (Polypep/Ulcenil) GERD OD or BD Syrup Polypep 10mg/5ml, Syrup Peptiban 10mg/5ml, Syp Ulcenil 10mg/5ml
BD
Fosfomycin 150 mg/kg/day TDS Syp Focin 250mg/5ml, Syp Focin DS 500mg/5ml
Flagyl (Metronidazole) 10 mg/kg/dose TDS Syp Flagyl 200 mg/5ml
Flumezenil 0.01 mg/kg diluted in 30 ml NS over 3 hours
Folic Acid (SAM) 4 mg stat dose, then 1 mg/day Tab Folic Acid 5 mg
Fortum (Ceftazidime) 100-150 mg/kg/day BD
GenM Next sheet Inj GenM 60 mg (1 ml Bicarb + 5 ml N/S= 10mg/1ml), Inj Gen M 120 mg
Gentamycin 7.5 mg/kg/day TDS
Excessive drooling: 0.02 - 0.1 mg/kg/dose (max 1.5 - 3.0 mg/dose) || Excessive drooling : TDS ||
Glycopyrrolate IV IM
Control of secreions IV/IM 0.004 - 0.01 mg/kg/dose Secretion control: QID
Excessive drooling : TDS ||
Glycopyrrolate ORAL 0.04 - 0.1 mg/kg/dose
Secretion control: QID
Gravinate (Dimenhydrinate) 0.5 mg/kg/dose TDS Syp Gravinate 125mg/5ml
Imipenam 20 mg/kg/dose TDS
Iron (Deficiency) 5 - 6 mg/kg/day of elemental iron OD/BD Syp Maltofer 50 mg/5ml, Syp IronOne 100mg/5ml, Syp Ferricure 100mg/5ml
Iron (Maintenance) 3 mg/kg/day of elemental iron OD/BD Syp Maltofer 50 mg/5ml, Syp IronOne 100mg/5ml, Syp Ferricure 100mg/5ml
Ivermectin 200 microgram/kg/dose (same as 0.2 mg/kg/dose) Stat dose Tab Ivermite 6mg
K-Lyte (Maintenance) 2 meq/kg/day OD Syp 7 meq/5ml (same as 500mg/5ml)
K-Lyte (Replacement) 4 meq/kg/day OD Syp 7 meq/5ml (same as 500 mg/5ml)
Ketress (Levamisole) 2.5 mg/kg Stat dose Syp Ketress 40mg/5ml
Klaricid inj 15 mg/kg/day BD
Klaricid oral 10 - 15 mg/kg/day BD Syp 125 mg/5ml, Syp 250 mg/5ml
Lasix (Frusemide) 1 mg/kg/dose (0.1ml/kg/dose) TDS, QID Lasix Injection
Lerace (loading) 40 mg/kg/dose Stat
Lerace (maintenance) 20 - 60 mg/kg/day BD
Lerace oral (Levetiracetam) 20 - 60 mg/kg/day BD Syp Lerace 100 mg/1ml, Syp Eplipsa 100mg/1ml
Linezolid (Nezkil) 10mg/kg/dose TDS
Loratidine <2 years not given,2 - 6 years 5mg/day, >6 years 10mg/day OD Syp Claritin, Syp Loratidine 5mg/5ml
Mannitol (Loading) 0.5 g - 1.0 g/kg/dose (5 ml/kg) Slowly over 3 to 6 hours, without dilution
Mannitol (Maintenance) 0.25 g/kg/dose TDS
Meropenam 20 mg/kg/dose TDS
Meropenam (Meningitic) 40 mg/kg/dose TDS
MgSO4 (Asphyxia) 250 mg/kg/day in 40 ml N/S over 30 mins OD x 3 days
MgSO4 (Asthma) 35 mg/kg in N/S infusion over 30 mins
MgSO4 (SAM) 30 - 60 mg/kg/day Syp MgSO4 500 mg/5 ml
Miltefosine <12 years or <30 kg: 2.5mg/kg/day, >12 years 50 mg OD OD Tablet Miltefosine 50mg
Myfol Drops (Folic Acid) 0-6m: 2 Drops OD | 7-12m: 3 Drops OD | 1-3 years: 5 drops OD OD Myfol Drops 30mcg/drop
Octreotide (Sandostatin) Infusion 1-5 McG/kg/hour 24-48 hours Inj Octreotide 100 McG/ml, infusion in N/2 5% without calcium and potassium
Ofloxacin 10-15 mg/kg/day BD Max single dose 400 mg
<1 yr: Not given, 5-10kg: 5mg OD, 10-20kg: 10mg OD, >20kg: 20mg
Omeprazole (Risek) GERD OD Risek Sachet 20 mg
OD
Orelox (Cefpodoxime) 8-10 mg/kg/day BD Syrup Orelox 40mg/5ml
Phenytoin (Loading) 20 mg/kg in 30 ml N/S over 20 mins
Phenytoin (Maintenance) 5 - 10 mg/kg/day BD
Phenytoin oral (Epitoin) 5 - 10 mg/kg/day BD Syp Epitoin 30 mg/5ml
Piperazine < 2 yr: 50 mg/kg/dose || 2-12 yr: 75 mg/kg/dose (max dose 2.5 g) Stat dose Syrup piperazine 750mg/5ml
Polymyxin (Neonate) 75000 IU/kg/day BD
Propanolol 0.5 - 1 mg/kg/day BD, TDS Tab Inderal 10 mg
Pyrantel 10 mg/kg/dose Stat dose Syrup Combantrin 250mg/5ml

Racedo/Hidrasec 1.5mg/kg/dose TDS, <3m: not advised, <9kg: 10 mg TDS, 9-13kg TDS Racedo sachet 10mg, Hidrasec infants 10mg, Hidrasec Children 30mg
20mg TDS, 13-27 kg: 30mg TDS, >27 kg: 60mg TDS
Ribavarin 15 mg/kg/day OD
Rifaximin 15-30 mg/kg/day TDS
Rigix (Cetrizine) <6 months not given, 2-5 years 2.5mg/day, >5 years 5 mg/day HS Syp Rigix 5mg/5ml
<1 yr: Not given, 5-10kg: 5mg OD, 10-20kg: 10mg OD, >20kg: 20mg
Risek (Omeprazole) OD Risek Sachet 20 mg
OD
Rivotril Drops 0.01-0.03mg/kg/day to 0.1-0.2mg/kg/day (2 drops/kg) TDS or HS Rivotril Drops 2.5 mg/ml (1 drop=0.1mg)
Septran (Co-trimoxol) 8-10 mg/kg/day BD
Septran (Co-trimoxol) PCP prophylaxis 10 - 20 mg/kg/day, 150 mg/m2/day BD Syp Septran
Septran (Co-trimoxol) UTI Prophylaxis 2 mg/kg/day OD
Sildenafil 0.5 mg/kg/dose QID Tablet 50 mg, 100 mg
Sodamint (Maintenance) 2 meq/kg/day 1 tablet = 4 meq, 1 meq = 84 mg
Sodamint (Replacement) 4 meq/kg/day TDS 1 tablet = 4 meq, 1 meq = 84 mg
Sodium Benzoate (Loading) 250 mg/kg
Sodium Benzoate (Maintenance) 250 mg/kg/day QID
Solucortif 10 mg/kg/day Max dose 250 mg
Spiromide (Spironolactone 50mg + furosemide 20mg) 1-3 mg/kg/day BD, TDS Tab Spiromide 50/20, Tab Spiromide 50/40 (calculate diuretic dose using 20/40mg)
Sulzone (Cefoparazone + Sulbactam) 80 mg/kg/day TDS
Syp Duphalac 1-2ml/kg/dose SOS, TDS Syp Duphalac, Syp Lilac
Tanzo (Neonates) 150 mg/kg/day BD
Tanzo (Pediatrics) 100 mg/kg/dose TDS
Tigecycline (Neonates) Loading @ 8 mg/kg, Maintenance 3-5 mg/kg/day BD
Transamine 10 mg/kg/dose TDS
Urso 5-10 mg/kg/day OD Syrup Urso 250 mg/5ml
Valganciclovir 16 mg/kg/dose BD
Valganciclovir 16 mg/kg/dose BD
Valium (Oral in febrile fits) 0.3 mg/kg/day for 3 days BD Tab Valium 5mg
Vancomycin 20 mg/kg/dose TDS
Velocef (Cephradine) 50 - 100mg/kg/day TDS Syp velosef 125mg/5ml, 250mg/5ml
Velosef (Cephradine) 50 mg/kg/day TDS Syp velosef 125 mg/5ml, 250 mg/5ml
Ventoline (Salbutamol) Nebulization 0.1 mg/kg/dose (approx 8 drops) <2 years, not given TDS, QID Ventoline drops (5mg/1ml)
Ventoline (Salbutamol) Oral 0.3 mg/kg/day, <2 years not given TDS Syp Ventoline 2 mg/5ml, Syp Bronkal 2mg/5ml
Vermox (Mebendazole) 100 mg (5ml) x 3 days BD Syp vermox 100 mg/5ml
Vibramycin (Doxycycline)(Cholera) 4 mg/kg/dose Stat dose Capsule vibramycin 100 mg
< 6 mo: 50,000 IU (20 drops Amax) | 6-12 mo: 100,000 IU (1.5 ml Amax) | >12 mo: 200
Vitamin A (Deficiency/ Mega dose in measels) Megadose on day 1, 2, 14 accoring to age
000 IU (2.5 ml Amax)
Amax drops 1 drop=2500IU, 20 drops= 50,000 IU, 1.5 ml = 100,000 IU, 2.5 ml =
Vitamin A (SAM) 5000 IU/day (2 drops Amax) OD
200,000 IU
Vitamin A and D (Pediamax drops) 1 - 2 drops/PO/day (0-6 mo 1 OD, >6 mo: 2 OD) OD Pedia max 1 drop = Vitamin A 1666 IU, Vitamin D 400 IU
Vitamin D (Deficiency) 10,000 IU/kg (Mega dose) Stat dose Injection Indrop D 200,000 IU
Vitamin D (Maintenance) 1-11 mo: 400 IU/day || >12 mo: 600 IU/day OD Dmax Drops 1 drop 400 IU
Vitamin E (SAM) 2.2 mg/kg/day Capsule Evion 400 mg
Vitamin K (SAM) 0.004 mg/kg/day Tablet Vitamin K 10 mg
Vitamin K inj 1 mg/kg (neonates) , 5mg/day OD
Voreconazole 16 mg/kg/day BD
Zatofen (Ketotifen) 0.05 mg/kg/dose BD Syp Zatofen 1 mg/5ml
Zinacef - Cefuroxime 50 - 100 mg/kg/day TDS Syp Zecef 125mg/5ml
Zinc (SAM) 2 mg/kg/day OD Syp Zincat 20mg/5ml
MICRO NUTRIENT SUPPLEMENTS

Drug Dose Frequency


Calcium Oral (SAM) 80 mg/kg/day BD Syp Cal-P 210 mg/5ml
Folic Acid (SAM) 4 mg stat dose, then 1 mg/day Tab Folic Acid 5 mg
Iron (Deficiency) 5 - 6 mg/kg/day of elemental iron OD/BD Syp Maltofer 50 mg/5ml, Syp IronOne 100mg/5ml, Syp Ferricure 100mg/5ml
Iron (Maintenance) 3 mg/kg/day of elemental iron OD/BD Syp Maltofer 50 mg/5ml, Syp IronOne 100mg/5ml, Syp Ferricure 100mg/5ml
K-Lyte (Maintenance) 2 meq/kg/day OD Syp 7 meq/5ml (same as 500mg/5ml)
MgSO4 (SAM) 30 - 60 mg/kg/day Syp MgSO4 500 mg/5 ml
Vitamin A (Deficiency/ Mega dose in < 6 mo: 50,00 IU (20 drops Amax) | 6-12 mo: 100,000 IU (1.5 ml Amax) | >12 mo:
Megadose on day 1, 2, 14 accoring to age
measels) 200 000 IU (2.5 ml Amax)
Amax drops 1 drop=2500IU, 20 drops= 50,000 IU, 1.5 ml/40 drops = 100,000 IU,
Vitamin A (SAM) 5000 IU/day (2 drops Amax) OD
2.5 ml/80drops = 200,000 IU
Vitamin D (Deficiency) 10,000 IU/kg (Mega dose) Stat dose Injection Indrop D 200,000 IU
Vitamin D (Maintenance) 1-11 mo: 400 IU/day || >12 mo: 600 IU/day OD Dmax Drops 1 drop 400 IU
Vitamin E (SAM) 2.2 mg/kg/day Capsule Evion 400 mg
Vitamin K (SAM) 0.004 mg/kg/day Tablet Vitamin K 10 mg
Zinc (SAM) 2 mg/kg/day OD Syp Zincat 20mg/5ml

COMMON FORMULATIONS
ACD plus drops 1-2 years: 1 drop OD || 3-12 years: 2 drop OD OD 1 drop contains daily requirement dose of vitamin A and D
ADEK Z drops 0-6 mo: 10 drops (0.5ml) || >6 mo: 20 drops (1 ml) OD 1 ml (20 Drops) Vit A 1500 IU, Vit D 600 IU, Vit E 15 IU, Vit K 40 mcg, Zinc 5 mcg
Appetite Stimulant BD, TDS Trimetabol, Tres Orix Forte, Vidaylin L
B Complex OD Syp Vidaylin M
0-6m: 2 Drops OD || 7-12m: 3 Drops OD || 1-3 years: 5
Myfol Drops (Folic Acid) OD Myfol Drops 30 mcg/drop
drops OD
Myfol Syrup 4-8 years: 2.5ml || 9-13 years: 3.75ml || >14 yrs: 5 ml OD Myfol syrup: 400 mcg/5ml
Pediamax drops (Vitamin A and D) 0-6 mo 1 OD drops || >6 mo: 2 drops OD Pedia max 1 drop = Vitamin A 1666 IU, Vitamin D 400 IU
ANTI MALARIAL

GenM (Artesunate)
Inj GenM 60 mg (diluted in 6ml) 120mg (diluted in 12 ml)
>20 kg 2.4 mg/kg/dose 0, 12, 24 hours
<20 kg 3.0 mg/kg/dose 0, 12, 24 hours
Then same dose in OD till child takes orally. Then shift to oral arceva for 3 days. but
minimum 3 doses of IV are necessary before shifting to oral.

Artem (Artemether)
Injection Artem 40 mg
On admission 3.2 mg/kg 0 hours
Per day till takes orally 1.6 mg/kg/day 24, 36 hours
Then same dose in OD till child takes orally. then shift to oral Arceva for 3 days. but
minimum 3 doses of IV are necessary before shifting to oral.

Arceva (Artemether plus Lumefantrine)


Dosing: OD for 3 days ( 3mg Artemether kg/day)
Weight Arceva 15/90/5ml Arceva DS 30/180/5ml
5 - 7.4 kg 7ml 3.5 ml
7.5 - 9.9 kg 10 ml 5 ml
10 - 12.4 kg 14 ml 7 ml
12.5 - 14.9 kg 17 ml 8.5 ml
15 - 17.4 kg 20 ml 10 ml
17.5 - 19.9 kg 24 ml 12 ml
NEONATOLOGY

Drug Dosage Type Age Weight Dose Frequency Notes


Renal Impairment. Serum Creat levels:
0.8 - 1.1 = 20mg/kg/dose × BD
Acyclovir 20mg/kg/dose TDS
1.2 - 1.5= 20mg/kg/dose × OD
>1.5 = 10mg/kg/dose × OD
Loading dose 5 mg/kg stat
Aminophylline
Maintenance 1 mg/kg/dose TDS
< 7 Days 100mg/kg/day BD
Non-septic dose
> 7 Days 100mg/kg/day TDS
Ampicillin
< 7 days 200mg/kg/day BD
Septic/ Meningitis
≥ 7 Days 200mg/kg/day TDS
< 1.2 kg 7.5mg/kg/dose OD
1.2 - 2.0 kg 7.5mg/kg/dose BD
< 7 days
Amikacin > 2.0 kg 7.5 – 10 mg/kg/dose BD
1.2 - 2.0 kg 7.5 – 10 mg/kg/dose BD
≥ 7 days
> 2.0 kg 10 mg/kg/dose TDS
< 14 days 60 mg/kg/day BD
Septic dose
> 14 days 100 mg/kg/day BD
< 14 days < 1.0 kg 100 mg/kg/day BD
Cefepime < 7 days 1.0 - 2.0 kg 100 mg/kg/day BD
Meningitic > 14 days < 1.0 kg 150 mg/kg/day TDS
> 7 days 1.0 - 2.0 kg 150 mg/kg/day TDS
Any age > 2.0 kg 150 mg/kg/day TDS
< 7 days 150 mg/kg/day BD
Septic Dose
≥ 7 days 150 mg/kg/day TDS
Cefotaxime
< 7 days 200 mg/kg/day BD
Meningitic Dose
≥ 7 days 200 mg/kg/day TDS
Colistin 50 000 – 75 000 IU/kg/day TDS 1 million units or 80 mg /vial
Loading Dose (fungal infection) 12 - 25 mg/kg PO or IV stat
Maintenance (fungal infection) 6-12 mg/kg/day OD
Fluconazole Syp Flu Z (50mg/5ml)
Loading Dose (oral thrush) 6 mg/kg stat
Maintenance (oral thrush) 3 - 6 mg/kg/day OD
< 7 days < 2.0 kg 100 mg/kg/day BD
Non Septic < 7 days > 2.0 kg 150 mg/kg/day TDS
Fortum (Ceftazidime) ≥ 7 Days 100 mg/kg/day TDS
< 7 days 150 mg/kg/day BD
Septic
≥ 7 Days 150 mg/kg/day TDS
Ganciclovir 6mg/kg/dose BD
INH (Isoniazid) 10 – 15 mg/kg/day BD
Levofloxacin 10mg/kg/dose BD
< 7 days 10 mg/kg/dose BD
Linezolid
≥ 7 Days 10mg/kg/dose TDS
< 32 weeks
20 mg/kg/dose BD
≥ 14 days
< 32 weeks
20 mg/kg/dose TDS
≥ 14 days
Septic
Meropenam ≥ 32 weeks
20mg/kg/dose TDS
< 14 days
≥ 32 weeks
30 mg/kg/dose TDS
≥ 14 days
Meningitic All ages 40 mg/kg/dose TDS
< 1.2 kg 7.5 mg/kg/day or EOD OD or EOD
1.2 - 2.0 kg 7.5 mg/kg/day OD
< 7 days
Septic > 2.0 kg 15 mg/kg/day BD
1.2 - 2.0 kg 15 mg/kg/day BD
≥ 7 days
Metronidazole (Flagyl) > 2.0 kg 30 mg/kg/day BD
< 2.0 kg 15 mg/kg/day BD
< 7 days
> 2.0 kg 22.5 mg/kg/day TDS
NEC
< 2.0 kg 15 mg/kg/day BD
≥ 7 days
> 2.0 kg 30 mg/kg/day TDS
Loading dose 20 mg/kg stat
Pyeona (Caffeine citrate) Injection pyeona 20 mg
Maintenance 5 mg/kg/day OD
< 30 weeks Containdicated
30 - 34 weeks
3 mg/kg/day OD
< 14 days
Tobramycin (Nebcin)
30 - 34 weeks
4 mg/kg/day OD
> 14 days
> 35 weeks 4 mg/kg/dose OD
Risek (Omeprazole) 0.5 - 1.5mg/kg/dose OD
Initial dose 60 - 80 mg/kg/day BD
Sulzone
Septic Dose 150 mg/kg/day BD or TDS
< 30 weeks
100 mg/kg/dose BD
<28 days

Tazocin
(Pipracillin (4mg) /
Tazobactum (500mg
NEONATOLOGY

Drug Dosage Type Age Weight Dose Frequency Notes


< 30 weeks
100 mg/kg/dose TDS
>28 days
30 - 36 weeks
Tazocin 100 mg/kg/dose BD
<14 days
(Pipracillin (4mg) /
Tazobactum (500mg 30 - 36 weeks
100 mg/kg/dose TDS
> 28 days
36 weeks
100 mg/kg/dose BD
< 7 days
36 weeks
100 mg/kg/dose TDS
>7 days
10 - 15 ug/kg/day PO
Thyroxine 0 - 3 months If T4 <5ug/dl OD
Upto 50 ug/day
Loading dose 20 mg/kg stat
> 28 weeks Serum Creatinine
15 mg/kg/dose BD
< 14 days <0.7 = 15mg/kg/dose × BD
0.7 - 0.9 = 20 mg/kg/dose × OD
> 28 weeks 1.0 - 1.2 = 15 mg/kg/dose × OD
15 mg/kg/dose TDS 1.3 - 1.6 = 10 mg/kg/dose × OD
> 14 days
>1.6 = 15 mg/kg/dose EOD
Vancomycin
Meningitis/Pneumonia < 28 weeks
15 mg/kg/dose 18 hourly Serum Creatinine:
< 14 days <0.5 = 15 mg/kg/dose XBD
0.5 – 0.7 = 20mg/kg/dose x OD
< 28 weeks 0.8 – 1 = 15 mg/kg/dose x OD
15 mg/kg/dose BD 1.1 – 1.4= 10mg/kg/dose x OD
> 14 days
>1.4 = 15mg/kg/dose x EOD
19

Calories Chart & Basics of Calories/Day Req


Dr M Tauseef Omer

FOOD Quanitity Calories (Kcal)


Carbohydrate 1g 4
Protein 1g 4
Fat 1g 9
Apple 1 small 80
Banana 1 medium 100
Grape Each 2
Mango 1 135
Orange 1 70
Pear 1 100
Peach 1 30
Pineapple 1 cup 80
Strawberry 1 cup 50
Watermelon 1cup 45
Carrots 1cup 45
Cucumber Each medium 30
Tomato 1 cup 30
Beef(meat only) cooked in oil 50 grams 200
Chicken(meat only) cooked in 50 grams 200
oil
Chicken Egg (large) fried 1 70
Fish 50 grams 80
Bread 1 slice 75
Butter 1 table spoon 100
Chocolate 25 g 150
Corn 1 cup/cooked 140
Potato (boiled) 1 medium 120
Rice (cooked) 1 cup 225
Whole milk 30ml 20
Formula BF 1 30 ml 20
20

Premature Formula 30 27
F100 100ml 100
F75 100ml 75
Pediasure 100ml 100

For ease, the Formula for Calories requirement / Day in a child is the
same as Holliday Segar method used to calculate total fluid
requirement per day .
i-e

(100ml/kg) or 1000ml fluid or 1000KCal for 1st 10 Kgs


(50ml/kg) or 500ml fluid or 500Kcal for next 10 Kgs (10-20Kg)
(20ml/kg) or 20 Kcal/Kg for every Kg beyond 20 Kgs.

Example:
Weight of Child : 10 Kg
Fluid Requirement per day : 1000ml
Calorie Requirement per day : 1000Kcal

Weight of Child : 20 Kg
Fluid Requirement per day : (1000 + 500) 1500ml
Calorie Requirement per day : (1000 + 500 ) 1500Kcal

Weight of Child : 22 Kg
Fluid Requirement per day : (1000+500+40) 1540 ml
Calorie Requirement per day : (1000+500+40) 1540 Kcal

Weight of Child : 8 Kg
Fluid Requirement per day : 800ml
Calorie Requirement per day : 800Kcal

Weight of Child : 17 Kg
Fluid Requirement per day : (1000 + 350 ) 1350ml
Calorie Requirement per day : (1000 + 350 ) 1350 Kcal
21

The young physician starts life with 20 drugs for each disease, and
the old physician ends life with one drug for 20 diseases.
COMMON PAEDIATRIC DRUGS DOSES:
Revision 2017- M Tauseef Omer

ANTI-PYRETIC,ANALGESC,ANTI-INFLAMATORY..
DRUG Brand Name Dose Indications

Acetaminophen Calpol syrup. 10mg/kg/dose every 6 Syrup Tablet/Drops Antipyretic


Panadol drops hours 120mg,160mg/5ml 80mg/ml, analgesic
(paracetamol) Tab
200,400mg

Ibuprofen Syrup.Brufen 10mg/kg/dose every 6 100mg/5ml *200mg Antipyretic


hours *400mg analgesic

DEXYBRUFIN DEXY,TERCICA 5mg/kg/dose every 6 100mg/5ml Antipyretic


hours analgesic

Aspirin disprin 90- Tab.300mg Anti-


130mg/kg/day,6hrly inflamatory

Nalbuphine nalbine 0.1-0.2mg/kg/dose Inj 10-20/ml


,6hrly,IV,IM,SC

Diclofenac Dicloran,voltran >1-3mg/kg/day Inj 75mg/3ml Tab 50mg

Morphine 0.15-0.2mg/kg/dose, Inj 15mg/ml


IV,IM,SC

Pancuronium Pavulon 60-100mcg/kg then Inj 2mg/ml Muscles Intubation


10-20mcg/kg/dose relaxant Only by
,20-60mint seniors..
Baclofen LioresaL, 10-15mg/day,8hrly Muscles
baclotab For 3 days relaxant

ANTIEMETICS:
Drug Brand Name dose indications
DIMENHYDRINATE Inj./syrup.Gravinate 0.5mg/kg/dose 12mg/5ml Antiemetic
every 6 hours
Metoclopramide Inj./syrup maxolon. 0.2- 5mg/5ml 10mg Antiemetic
Inj.metomide 0.5mg/kg/day
every 6 hours Can Cause sever
Dystonic Reactions
Not
Recommended in
paeds anymore.
22

Domperidone Syrup.Peridone. 0.5mg/kg/dose 5mg/5ml 10mg Antiemetic


Syrup Domel every 6 hours
Inj.motilium Can cause severe
dystonic reactions

Not
Recommended in
paeds anymore.
ONDANSETRON Inj.tab Onset 0.15mg/kg/dose 2mg/ml 2,and Chemoth-vomiting
4mg
ANTIBIOTICS
QUINOLONES:
drug Brand Name Dose strength indications
Ciprofloxacin Syrup.novidat ORAL:20- *125mg/5ml Tab.100mg Typhoid.
Tab.novidat. 30mg/kg/day *250mg/5ml ,250mg UTI’S.
Syrup.Gavel. every 8-12hrs. and
Syrup.Mytel I/V:4- ,500mg
15mg/kg/day
every 8-12hourz
Nalidixic Acid Susp.negram. 55mg/kg/day 250mg/5ml 500mg Lower UTI’s
Tab.negram every 6 hourly
CEPHALOSPORINS
Drug Brand Name Dose indications
1st Generation
Cephalexin Ceporex 25-100mg/kg/day every 6 hrz. *125mg/5ml Drops:125mg/m
*250mg/5ml l
Cephradine Syp.velosef 50-100mg/kg/day every 6 hrz *125mg/5ml. 250mg/vial.
*250mg/5ml 500mg/vial.
2nd generations

Cefaclor Syp.ceclor 20-40mg/kg/day every 8 hrly 125mg/5ml. DROPS:125mg/


250mg/5ml. ml.
Cefuroxime Inj.zinacef 50-100mg/lg/day every 8hrly. 125mg/5ml, 250mg/vial.
Syp zecef 250mg/5ml 750mg/vial.
3rd generations
Ceftriaxone Inj.Rocephin. 50-75 mg/kg/day every 12 250mg/vial. Liver toxity
Inj.oxidil. hrly. 500mg/vial.
Inj.dayline. Meningitis:100mg/kg/day 1g/vial.
Inj.pathocef. every 12hrly.
Inj.titan
Cefotaxime Inj.claforan. 100-200mg/kg/day every 250mg/vial Renal toxicity
Inj,Yarker. 12hrly 500mg/vial.1g/
vial.
Ceftazidime Inj fortum 100-200mg/kg/day.8hrly Anti pseudomonas
CEFIXIME SYP.cefspan. 10mg/kg/day in 12hrz.or 100mg/5ml.
Syp.caricef. 24hrz. SD.200mg/5ml
Syp.cefiget.
Syp.synocef.
Syp.cef-od
Syp.cefim.
Amoxicillin Syp.Amoxil. 20-40mg/kg/day every 8- 125mg/5ml. Cap.250mg and
Syp.suprmax 12hrz. 250mg/5ml 500mg
Amoxicillin- Syp/inj. 20-45mg/kg/day every 8- 156mg/5ml. Tab
clavulanate Augmentin, 12hrs. DS syrup 357mg,625mg,
Calamox 80-90mg/kg/day for otitis 312mg/5ml and 1gm
media. 457mg/5ml
AMPICILLIN Syp.inj 100-300mg/kg/day every 8 125mg/5ml 125mg/5ml Gram positive..
Penbritin hrly 250mg/5ml .250mg/5ml
23

Metronidazole Tab.,Syrup,Inj. 35-50mg/kg/day every 8hrly Syr.200mg/5ml Tab


Flagyl 200mg,400mg
Meropenem Inj.meronem 60-120mg/kg/day,every 8hrly 500mg and
(as infusion in 20 c.c Normal 1Gm
Saline over 30 minutes)
Vancomycin Inj.vanco 40-60mg/kg/day, every 8hrly Inj:500mg/vial, Staph and resistan
(as infusion in 20 c.c Normal 1g/vial. gram positive
saline over 45 minutes) infections
> Much slower than
Meropenem.
AMIKACIN Inj.gracil 7.5-10mg/kg, 8 hrly 25mg/ml,
250mg/ml

Tazobactem+Pipera Tanzo 150-300mg/kg/day,8hrly 2gm Nosocomial


cillin pipercacillin pneumonia
PENCILLIN-G Inj.Benzyl- 1-4 lac/kg/day,6hrly 5-10 lac Don’t Forget Streptococcal
pencillin units/vial Test Dose infections
Benzathine Penidure LA, 6/12 lac unit IM,3WEEKLY Inj 6/12 lac Rheumatic fever
Penicillin INJ Benzibiotic Don’t Forget prophylaxis
Test Dose
Clarithromycin Susp 7.5-15mg/kg/day,12hrly 125mg/5ml Tab.500mg IV INFUSION IN
Klaricid,pathoc (if i/v,, then as infusion over SALINE OVER 4
in, 30 min) HR
Azithromycin Syp 10mg/kg,OD,3days 200mg/5ml
Azit,zeenase
Artemether Artem 3.2mg/kg IM state,then Inj 40mg. malaria
1.6mg/kg ,OD,4days Cap.80mg
Atrtemther+lumefa Comether, 3mg/kg/day Syp.15mg
ntrine artemether/5ml
arceva (15/90)
(30/180)
Tab 40/240
Tab 80/480
Quinine sulfate IV 10mg/kg loading over4 hr Oral..double Cerebral malaria.
then same as 8hrly dose
Chloroquine nivaquine 10mg/kg stat then 5mg/kg aftr 50mg/5ml TaB 150MG Prophylaxis,5mg/k
6 hr then 5mg/kg OD for g,once weekly.
2days.

ANTITUBERCULOUS
Give before breakfast.

ISONIAZID ISONEX 10mg/kg/day,OD Syp50mg/5ml Tab.100mg Prophylaxis5-


10mg/kg/day OD
RIFAMPICIN Rimactane,rifdi 15mg//kg/day OD,1/2HR b4 Syp.100mg/5ml Tab.300, Nesseria
n Breakfast 450mg carrier..10-
20/kg/day
OD,4days
PYRAZINAMIDE 30mg/kg/day,OD Syp.250mg/5ml 500mg
ETHAMBUTOL myambutol 25mg/kg/day OD 40Omg
>5year
STREPTOMYCIN - 20-40mg/kg/day,OD,IM Inj 1G
Myrin Rifampicin/ 150/
INH/ 75/
Ethambutol 300
24

Myrin-P Rifampicin/ 150/


INH/ 75/
Ethambutol/ 275
Pyrazinamide 400

Other Dosage available as :

120/
60/
225/
300
Trimethprim+sulfa septran 8-10mg/kg/day,12hrly Syp TMP 40mg Tab 100mg\ PCP..10-
methoxazole UTI prophylaxis 2mg/kg ,OD DS..200mg 20mg/kg/day
UTI,BOILS
ANTIVIRAL
ACYCLOVIR Zovirax,aclova 20 mg /kg/dose (give 8 hourly) Syp 200mg/5ml Inj 250mg Herpes simplex
Acylex and varicella zoster
as infusion over 60 minutes Encephalitis

(The dosage for


skin lesion is
10mg/kg/dose
given 8 hourly)
ANTIHELMINTHIC
MEBENDAZOLE Vermox 100mg,12hrly,3days Syp 100mg/5ml Tab 100 mg antihelminthics
Vermol >2yr children Tab 500 mg

Albendazole zentel 200mg,single dose 100mg/5ml Tab.200mg antihelmintjics


>2 yr children
Levamisol ketrax 2.5mg/kg ,single dose 40mg/5ml antihelminthics

INOTROPIC AGENTS
DOPAMINE Inj.Inotropin 5-15mcg/kg/min or 200mg/5ml
0.012*dose*weight
DOBUTAMINE Inj.Dobutrex 10-20mcg/kg/min 250mg/5ml
0.01*dose*weight

(These formulae are for


Dobutrex250mg/5ml
Dopamine 200mg/5ml
- Do check the strength of your
injections before you advise on
t/m ticket)

The Above two Inotropes, Dobutamine and Dopamine are given as a continuous infusion for whole 24 hours. Never stopped even if
the patient is being transported or being given a blood transfusion or undergoing any procedure.
If these two drugs do not give response , then Infusion of NorEpinephrine (0.1 micro gram /Kg/min is started along with these)

DIGOXIN LANOXIN IV Digitilizing dose 0.10- Give half dose of total dose OR maintence
0.30mg/kg divided in fractions stat. 0.1-
ot PO 0.04mg/kg divided ib Then1/4th 8hr later, 0.015mg/kg/day
fractions as Then1/4th 16hr later 12hry
Thengive 1/4th as
maintenance dose after 24
hr IV OR PO..
25

Adrenaline 1:10000 sol..used 0,1ml/kg/dose IV 5mint upto Inj 1:1000,


(made by dilution) 0.5ml/kg 1ml/1mg
1mg is 1000 Units
Atropine 0.02mg/kg/dose Sinus bradycardia
and
organophosphorus
ANTIHYPERTENSION
Propranolol inderal 0.5-1mg/kg/day6-12hrly TOF..0.15-0.25mg/kg/dose
slow IV repeat after 15
mint.
PO2mg/kg/day,6Hrly
Nifedipine Adalate 0.25-0.5mg/kg/dose Tab.20mg Cap.10mg
PO,SL,6hrly
Methyledopa aldomate 10mg/kg/day,6-12hrly Inj50mg/ml,tab.250,500mg
upto65mg/kg/day
Captopril Capoten,capase 0.5-0.6mg/kg/dose,6hrly Tab12.5mg,25mg
Upto 6mg/kg/day
Sodium Nitropruside Nipride 0.25-6ug/kg/min
Diaxoxide Hyperstat IV 3-5mg/kg repeat aftr 15 15mg/ml
mint
Hydralazine aspresoline 0.15mg/kg/dose IV,
Repeat 90 mint
ASTHMA
Salbutamol Ventoline Oral0.2-0.4mg/kg/day,8hrly Syp.2mg/5cc,sol.5mg/ml, Nebulization
0.1-
0.2mg/kg/dose
Aminophyline 5mg/kg IV ovr 20 mint. Inj 250mg/10cc
Inhaler
Beclomethasone becotide 50-100mcg,2-4 times a 50ug/puff
day,MAX 10 puff daily
Salbutamol ventoline 2 puff,2-4 times aday 100 ug/puff
Fluticasone flunisolide 4 puff aday
Nebulization
Salbutamol Resp. solution <1 yr 0.1mg/kg/dose in 1.5cc Comes in variable strength Ref. Harriet Lane
Normal Saline (nebulize 4 to 6 in our ICU. 20th Ed
hourly) usually,
1-5 Yr 2.5mg/dose made in 5mg/1cc solution
NS (nebulize 4 to 6 hrly) May take it with syringe
>12 yr 2.5 to 5 mg /dose
(nebulize 4 to 8 hrly)
Ipratropium Atrovent2% <12 yr 0.25 mg /dose repeat Comes in variable strength Ref. Harriet Lane
after 20min, then 2-4 hrly as in our icu, 20th Ed
needed. Usually,

>12 yr 0.5mg /dose repeat after 0.25mg/ml


30 min, the 2 to 4 hrly as
needed
Beclomethasone Clenil Aerosol 0.04 mg nebulized X B.D Check strength on Vial that Ref. Harriet Lane
is available in ICU and 20th Ed
dilute in 2cc Normal
Saline.
26

Epinephrine Croup: (0.5mL/Kg of 1:1000 Ref. Harriet Lane


solution diluted in 3ml 20th Ed
Normal Saline )(with
maximum dose as :
4Year or less > 2.5ml/dose
More than 4 yr 5ml/dose

Post Endotracheal Extubation :


0.1 ml / kg of 1:1000 in 1.5 cc
normal Saline
ANTICOAGULANTS
Heparin 50unit/kg IV bolus,then Adjust according
infusion 10-25/kg/hr to APTT
Warfarin 0.1mg/kg/day PO, Maintence 0.05- Adjust according
0.34mg/kgday,6hrly to PT

DIURETCS
Mannitol 20% Diuretic.0.25mg/kg/dose in 30 20gm/100ml Cerebral
After checking B.P edema.initial 0.5-
1gm/kg/dose
then.0.25-
0.5mg/kg/dose
Acetazolamide Diamox 250 mg Diuretic (30 mg/kg/day)
tab divided 8H or 6 H
Frusemide lasix 1-2mg/kg/dose,BD,TDS upto Inj1ml/10mg,tab20,40mg
6mg/kg.dose,
Spironolactone aldactone 1-3mg/kg/day,12hrly 25/100mg
Naloxone 0.01-0.2mg/kg/dose,at 3mint 0.04mg/ml Morphine
interval poisoning

ANTICONVULSANTS/SEDATIVES:
DIAZEPAM Inj.Valium 0.1-0.5mg/kg/dose. Inj.10mg/2ml vial, Fits/epilepsy
Tab.2mg,5mg,10mg.
If given i/v, give slowly over
60 seconds
PHENOBARBITONE Debritone,pheno Loading:20mg/kg stat, Tab.30mg Fits/epilepsy
Mainten.:4-8mg/kg/day every Syp.20mg/5ml
12-24 hrs Inj 200mg
MIDAZOLAM Inj.Dormicum 0.1mg/kg/dose,every 5mint 5mg/5ml Start with
upto 5 time..max 0.6mg/kg Infusion 0.1-
0.2ug/kg/min
If given i/v, give slowly over
60 seconds To get response ,
may increase to
18ug/kg/min
PHENYTOIN DILANTIN Load with inj phenytoin Syp 125mg/5ml epilepsy
20mg/kg/dose in 20c.c normal
Syp epitoin saline over 20min.
then;
5-10mg/kg/day,BD
CLONAZEPAM RIVOTRIL 0.01- Drops2.5mg/ml ?? epilepsy
0.03mg/kg/day,8hrly,increase
0,5mg/day for 3days upto tab 0.5 mg
0.3mg/kg/day tab 2mg
27

Sodium valproate Epival,epilim 10mg/kg/day,12hrly,increase5 250mg/5ml epilepsy


mg/kg/week upto
60mg/kg/day Tab 250mg
Tab 500mg
(hepatic side effects)
Levetiracetam Lerace 10 mg/kg/dose X 12H 100mg/ml drops
Klevra May increase to max
Levitra 30mg/kg/dose X 12… increase Tab 250mg
2 Weekly if tolerated . tab 500mg
(Renal Side effects) Tab 750 mg
LAMOTRIGINE lamictal 2mg/kg/day,12hrly for 2week Tab25,50,100mg Adjuvant epilepsy
then 5hen 5mg/kg/day
TOPIRAMATE TOPAMAX >2yr ..25mg at nite..then Tab.25,50mg Adjuvant epilepsy
increase 1-3 weeks by 1-
3mg/kg/day upto5mg/kg/day
CHLORAL HYDRATE For Sedation : 8mg/kg/dose 250mg/5ml ?? sedative

ANTIALLERGIC AND STEROIDS


Chlorpheniramine Tab/Syp.Avil. 1-2mg/kg/day every 6 hrz.or 15mg/5ml 22.7mg/2ml
1TSF for 10kg.
<10kg ½ TSF. tab 25mg
>10kg 2TSF. tab 50mg
tab 75 mg
Loratidine Syp.Antial,lorel 0.2-0.3mg/kg/dose,OD 5mg/5ml Tab 10mg

Cetrizine Rigix,zyrtec 0.2-0.3mg/kg/dose,OD 5mg/5ml 10mg


Diphenhydramine benadryl 4-6mg/kg/day,6hrly IV,PO 13.5mg/5ml
Hydrocortisone Inj.Solucortef Septic shock:35-50mg/kg/d,4- 100mg/2ml.
6hrly 250mg/2ml.
500mg/4ml
Acute asthma 5mg/kg/dose
stat,1-2mg/kg/day 6hrly
Stress dose Hydrocortison in Must get
CAH: Endocrinology
if mild stress(like consult.
URTI/AWD/etc), increase
dose to 3 times.

if comes in crisis/obtunded,
then,
100mg/m2 per day
Dexamethasone decadron Anti-inf..0.3mg/kg/day,6- 4mg/ml.. Tab 0.5mg
12hrly,
Meningitis..0.6mg/kg/day,6hrl
y for 4 days
Cerebral edema..loading 1-
2mg/kg/dose once then 0.2-
0.5mg/ kg/day,6hrly
Before Extubation..
0.25mg-0.5mg/kg/day,8hrly
28

Prednisolone Deltacortil Asthma and asthma 1- Tab Deltacortil


2mg/kg/day, PO, (Tab 5mg)
Nephrotic Syndrome: Stat
with 60mg/m2 /Day Syp Steron
(15mg/5ml)
Formula to Calculate Surface
area from weight (x) is : Syp Neupred

S.A = (4x + 7) / (90 + x)


= _____ m2

Syp Steron (15mg/5ml)

Methyl Prednisolone Acute Inj


acetate asthma..2mg/kg/dose,6hrly. 40mg,125mg,500
Acute spinal cord injury mg
(Depo-Medrol) 30mg/kg in 15 mint folowed
by 5mg/kg/hr for 23 hr. Tab 2,4,,8,16,32
mg
Methyl Predniolone
Sodium Succinate Also indicated in :
Sensitivity
(Solumedrol) Transplantation
Cerebral Edema
UC
crohns
Aspirationpneumonia
SJS
rheumatoid arthritis
Osteoarthritis
Dermatoses
Hay Fever
Collagen Disorders
NEWER ADDITIONS
Fluconazole Load with Antifungal Both syrup and Iv Syp
12mg/kg/dose, forms available. Diflucan(50mg
then 6mg/kg/day(24 /5ml)
hours after loading
dose) Syp Fzole

Ursodeoxycolic Neonate: Advised in cholestatic Syp Urso


Acid 10mg/kg/day (OD jaundice (250mg/5ml)
dose)

Child:
20 mg /kg/day
(divided BD)
Rifaxamine 10mg / kg /dose Advised in Hepatic Tab Rifaxa
(OD) per NG failure to clear GUT off 200mg
ammonia producing
bacteria. Tab Nixaf
550mg

Tab Xifaxa
550mg
29

Sodium benzoate 1ml per Kg per NG Advised in hepatic May be


failure to bind free acquired from
ammonia in GIT Children
Hospital
Lahore’s
Pharmacy
Nitazoxanide 1-3 year: 100mg Advised in chronic Syp NT-TOX
(100mg/5ml) PO BD for 3 days giardiasis (100mg/5ml)

4-11 year: 200mg Tab NT-TOX


PO BD for days 500mg

>12 years 500mg Syp


PO BD for 3 days Atizox(100mg/
5ml)

COMMON FORMULAE :
Many Drugs are given according to Surface Area of Pt.
Formula to Calculate Surface area from weight (x) is :

S.A = (4x + 7) / (90 + x)


= _____ m2

Fluid rate

what are the formulas to calculate drops rate of a simple dripset, B.T set , and
microburette ???

In in simple drip set 15 drops = 1 ml


In Blood Tx Set 12 drops = 1ml
In microdrip set (pediadrip) 60 micro-drops =1 ml

Various Formulae are given below.

1) Simple Calculation Formula is:

Fluid in ml *drops/time in min

2) Drop index Formula is :

Fluid in ml ×drop index/time in min

the drops will come out for one minute !


30

drop index is 15 for dripset ,, 60 for M.B (pediadrip) and 10 or BT set.

3) FOR BURETTE.. FLUIDS(ml)/TIME(hrs)

4) for DRIP.............FLUIDS(ml)/TIME(hrs) MULTIPLY BY 1/4.....e.g to give 500 ml in 8 hrs


it will be approx 62 micro drop/min or 15 macrodrops.

Calculation of GFR
Many drugs , specially antibiotics need adjustment in their DOSES, or their
INTERVALS of administration . This is decided on the basis of GFR , which may be
calculated as:

GFR = kL/SrCreatinine

Where K is constant
L is length/height
Sr creatinine

K values:

LBW infants in 1st year 0.33


Term AGA in first yr 0.45
Children and adolescent girls 0.55
Adolescent boys 0.70

Check at the end of Harriet Lane : Drugs in Renal Failure to see adjustment of
DOSES, or intervals or BOTH.

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