Pathology: The
Study of Disease
Pathology is the study of disease,
focusing on the morphological,
functional, and biochemical changes in
cells, tissues, and fluids of the body.
Dr. MUHAMMAD IMRAN
Assistant Professor
preencoded.png
The Evolution of Pathology
1 Ancient Times
Early understanding of disease was
limited to macroscopic observations.
2 Modern Era
Advancements in microscopy and
technology have allowed for a deeper
understanding of disease at the
cellular and molecular levels.
3 Present Day
Pathology continues to evolve with
new technologies and research,
leading to more precise diagnoses
and treatments. preencoded.png
The "Why" and "How" of Disease
1 What 2 Why 3 How
Pathology helps It investigates the It explores the
us identify what underlying mechanisms by
is wrong in the causes of disease. which diseases
body. develop and
progress. preencoded.png
Branches of Pathology
Medical Pathology
Focuses on diseases in humans.
Veterinary Pathology
Studies diseases in animals.
Diagnostic Pathology
Identifies the nature of disease using various tools.
Forensic Pathology
Investigates medicolegal issues related to death.
preencoded.png
More Branches of Pathology
Surgical Pathology
Studies biopsy material obtained during surgery.
Environmental Pathology
Examines the impact of the environment on disease.
Toxicological Pathology
Investigates the effects of toxic substances on disease.
Zoo and Wildlife Pathology
Studies diseases in zoo and wild animals.
preencoded.png
Specialized Areas of Pathology
Immunopathology Clinical Pathology Experimental Pathology
Studies tissue Focuses on Studies diseases
injury caused by laboratory analysis through
the immune of disease. experimental
system. methods.
preencoded.png
General and Systemic Pathology
General Pathology Systemic Pathology
Deals with common Studies diseases with
denominators of disease and reference to the system of
mechanisms of their involvement.
production.
preencoded.png
Key Terms in Pathology
1 Lesion
An abnormality, usually structural, but
can also be functional or biochemical.
2 Pathognomonic
A specific abnormality found only in a particular condition.
3 Biopsy
Tissue removed from a living organism for diagnostic purposes.
4 Autopsy/Necropsy
Examination of a dead body for diagnostic purposes.
preencoded.png
Understanding Disease
1 Disease
Clinically apparent dysfunction due to abnormalities at
the cellular and tissue level.
2 Pathogenesis
The mechanism of development of disease, involving
step-by-step progression.
3 Diagnosis
Naming a disease based on clinical signs, laboratory
tests, and lesion characteristics.
4 Prognosis
The possible outcome of a disease, whether favorable or
unfavorable. preencoded.png
Tools of Pathology
1 Eyes and Hands
Direct observation and palpation are essential tools.
2 Light Microscope
Used to examine tissue samples at a microscopic level.
3 Histochemical Stains
Used to highlight specific components of tissue samples.
4 Advanced Microscopy
Includes darkfield, phase contrast,
fluorescence, and electron microscopy.
preencoded.png