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Assignment 10b

Allopurinol, a xanthine oxidase inhibitor, is primarily used to treat gout, hyperuricemia, and prevent uric acid kidney stones. It is typically taken once daily, orally or intravenously in severe cases, and should be administered after meals with plenty of fluids. Common side effects include nausea and diarrhea, while contraindications include severe kidney disease and previous allergic reactions to the drug.

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27 views2 pages

Assignment 10b

Allopurinol, a xanthine oxidase inhibitor, is primarily used to treat gout, hyperuricemia, and prevent uric acid kidney stones. It is typically taken once daily, orally or intravenously in severe cases, and should be administered after meals with plenty of fluids. Common side effects include nausea and diarrhea, while contraindications include severe kidney disease and previous allergic reactions to the drug.

Uploaded by

bhandarisudip37
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Research Assignment

1. Name and Classification of the Drug

• Name: Allopurinol (Brand names: Zyloprim, Aloprim)

• Classification: Xanthine Oxidase Inhibitor (Used for Gout and Hyperuricemia)

2. Three Common Indications for This Drug

1. Gout (a condition caused by high uric acid levels leading to painful joint inflammation)

2. Hyperuricemia (high uric acid levels in the blood, which can cause kidney stones)

3. Prevention of uric acid kidney stones

3. How Often Is It Taken?

• Typically once daily, but some patients may require twice daily dosing based on their uric acid
levels.

4. By Which Route(s) Is It Taken?

• Orally (tablet)

• Intravenously (IV) (only in hospital settings for severe cases)

5. Special Instructions for Administration?

• Take after meals with a full glass of water to reduce stomach upset.

• Drink plenty of fluids to help flush excess uric acid through the kidneys.

6. Possible Side Effects?

• Common: Nausea, diarrhea, drowsiness

• Serious (rare): Allergic reactions (rash, itching), liver toxicity

7. Contraindications?

• Severe kidney disease (unless under careful monitoring)

• Allergic reaction to allopurinol in the past

8. Three Sources Used for This Assignment

1. Health Canada – Medication safety guidelines

2. Canadian Pharmacists Association – CPS

3. Mayo Clinic – Drug information

9. Why Did You Choose This Drug to Research?


• Uric acid buildup can cause painful conditions like gout and kidney stones. Understanding how
allopurinol works can help prevent these complications.

10. Most Interesting Fact Learned About This Medication?

• Allopurinol does not treat acute gout attacks; instead, it prevents future attacks by lowering uric
acid levels over time.

Three Sources Used for This Assignment (APA Citation) (3)

• Health Canada. (n.d.). Medication safety guidelines. Government of Canada. Retrieved from
https://www.canada.ca/en/health-canada.html

• Canadian Pharmacists Association. (n.d.). Compendium of pharmaceuticals and specialties (CPS).


Retrieved from https://www.pharmacists.ca

• Mayo Clinic. (n.d.). Allopurinol (oral route) description and brand names. Retrieved from
https://www.mayoclinic.org

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