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Vmethod Forensic Toxicology SCRN

The document describes a rapid screening method for forensic toxicology that allows for the accurate testing of 664 compounds in under 10 minutes using the X500R QTOF System. It emphasizes straightforward sample preparation, efficient workflows, and the ability to reduce backlogs in crime labs. Additionally, it highlights the support provided by SCIEX for maximizing lab productivity and ensuring high-quality results.

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Amin Soleimani
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0% found this document useful (0 votes)
216 views4 pages

Vmethod Forensic Toxicology SCRN

The document describes a rapid screening method for forensic toxicology that allows for the accurate testing of 664 compounds in under 10 minutes using the X500R QTOF System. It emphasizes straightforward sample preparation, efficient workflows, and the ability to reduce backlogs in crime labs. Additionally, it highlights the support provided by SCIEX for maximizing lab productivity and ensuring high-quality results.

Uploaded by

Amin Soleimani
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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664 Forensic

Toxicology
Compounds

Rapid
Screening
Method
Forensic
Toxicology
Screening Multiple
matrices
664 Forensic Toxicology Compounds in 10 mins
Accurate testing of 664 forensic toxicology compounds in less than 10 minutes is now a reality with this vMethod™
from SCIEXLabs™. Detect a comprehensive suite of familiar and novel psychoactive forensic analytes using the
X500R QTOF System. Reduce the risk of compromised results by analyzing your whole blood or urine samples with
High-Resolution Mass Spectrometry (HRMS) that enables your crime lab to deliver concise and comprehensive analysis
of your forensic evidence.

Straightforward Sample Preparation


There is nothing complicated about the way in which your samples “This broad-based drug screening
are prepared. Using the method detailed in the Standard Operating method offers a good balance
Procedure (SOP) you will be able to efficiently extract your analytes between chromatographic separation
in a quick and timely manner without risking contamination of and analysis time. The ten-minute
your evidence. runtime allows for increased workflow,
and overall analysis efficiency.
The mass acquisition is designed
Plug and Play to acquire analytes of interest in
a semi-non-targeted fashion, allowing
The 664 compounds included in this vMethod, have all been optimized for the
for high specificity in tracing fragment
X500R QTOF system. This screening method includes all the Retention Times, ions back to precursor ions, as well as
High Resolution Mass Spectrometry (HRMS) and HR-MS/MS information you the potential for more comprehensive
need to deliver defensible results that withstand cross examination. retrospective data analysis for
determination of analytes not within
the current scope of data processing.”
Backlog Reduction
With a runtime of just 10 minutes, there is minimal chance of generating Dr Alex Krotulski
a costly and time wasting backlog. This vMethod from SCIEXLabs has the The Center for Forensic Science
ability to deliver clear accurate data so you can run more samples and grow Research & Education
your labs potential and enhance its reputation in quality.

For Research Use Only. Not for use in diagnostic procedures.


Assay Performance Assay Components
Value
The sample preparation protocol detail
all the steps required for the clean-up
Compounds for Screening 664
of both blood and urine samples for
Scan Mode HR-MS/MS
this 664 forensic compound screen.
Sample Prep
Polarity Positive

All the legwork has been done.


Operating System SCIEX OS
Get the detailed, verified LC separation
conditions with retention times using
Instrument X500R QTOF System
a Phenomenex Kinetex® 2.6µm
HPLC
phenyl-hexyl 50 x 4.6mm column.
Injection Volume 10µL
This method includes the X500R
Whole Blood
Sample Matrices
Urine
QTOF System, a high resolution mass
spectrometer which enables powerful,
HR-MS/MS Runtime 10 mins unique workflows that deliver a new
level of confidence in your data.

LC Separation Column
Phenomenex Kinetex®2.6µm Mass Spec
phenyl-hexyl 50 x 4.6mm

Included is SCIEX OS, the software you


need to quickly process large batches
of screening samples with accuracy
and precision.
Software

A helping hand to get you started.


A dedicated SCIEX Support team
member will be available to answer
questions, or submit your questions
Service / Support on the fly in our online community.
Your Success is Our Success
We take it personally
As a SCIEX customer you have access to a world-class customer support organization.
Wherever you are, we’re there with you as a trusted partner to answer questions, provide
solutions, and maximize lab productivity.

Our customer support organization has access to the latest product updates, software
revisions, methods and repair procedures to make sure that you stay on top of your game.

AB Sciex is doing business as SCIEX.


When you have questions, we have answers.
© 2017 AB Sciex. For Research Use Only. Not for use in diagnostic
sciex.com/Forensic vMethod procedures. The trademarks mentioned herein are the property of
AB Sciex Pte. Ltd. or their respective owners. AB SCIEX ™ is being
used under license.
RUO-MKT-07-6385-A 09/2017

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