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Aum 222 Antimicrobials Test Questions

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DEPARTMENT OF PHARMACY TECHNICIAN

ELITE INTERNATIONAL COLLEGE OF HEALTH SCIENCE AND


TECHNOLOGY, ZARIA
SECOND SEMESTER CONTINUOS ASSESMENT (C.A 1
ANTIMICROBIALS)
AUM 222: ACTION AND USES OF MEDICATIONS. TIME ALLOWED: 1HR
STUDENT REG. NO: …………………………………………... MON, 12TH FEB, 2025
(PART 1 MULTIPLE CHOICE QUESTIONS)

(1) Antimicrobials are:


A. Agents that selectively kills microorganisms
B. Selectively inhibit the growth of microorganisms
C. All of the above
D. None of the above

(2) Chemotherapeutics are the antimicrobial agents which are


obtained by chemical synthesis?

A. TRUE
B. FALSE

(3) Antibiotics are the antimicrobial agents produced by


microorganisms, which selectively suppress the growth of or kill
the microorganisms at very low concentrations?

YES OR NO

(4) One but none is an example of Properties of an ideal antibiotic


A. Should have broad spectrum of antimicrobial activity.
B. Should exert its action in low concentration.
C. Should have more bactericidal activity rather than bacteriostatic.
D. Should interfere with the host natural defense mechanism

(5) Aminoglycosides are examples of bacteriostatic antimicrobials


TRUE OR FALSE
(6) Tetracyclines are examples of bactericidal antimicrobials?
YES OR NO

(7) Azole derivatives: e.g., Metronidazole, Ketoconazole,


Fluconazole are classification of drugs based on chemical
structures?
A. True
B. False

(8) Classification on the basis of Mode of action /

Mechanism of action except?


A. Drugs that act on cell wall e.g., penicillin’s
B. Drugs that act on DNA gyrase example Levofloxacin
C. Drugs that interfere with DNA synthesis example zidovudine
D. None of the above

(9) All but none is an example of classification based on the diseases they treat?
A. Antimalarial
B. antiamoebic
C. antitubercular
D. All of the above

(10) Broad spectrum antibiotics: An antibiotic that is effective


against a wide variety of microorganisms.?

TRUE OR FALSE?

(11) Narrow-spectrum antibiotics: An antibiotic that is specifically


effective against a limited group of microorganisms are?

A. Antibiotics primarily effective against gram positive


microorganisms’ bacteria
B. Antibiotics primarily effective against gram negative
microorganisms’ bacteria
C. All of the above
D. None of the above

(12) All but one is an example of 3rd generation cephalosporins?


A. Ceftriaxone
B. cefixime
C. cefuroxime
D. cefotaxime

(13) Antibiotics are Indicated in the parasitic infection?

A. TRUE
B. FALSE

(14) Chemotherapeutics Indicated in the parasitic infection?


A. YES
B. NO

(15) The following factors are considered while selecting antibiotics for a patient except?
a. Cost and affordability
b. Site of infection
c. Patient factor
d. None of the above

(16) one but none is an example of aminoglycosides


A. kanamycin
B. Gentamycin
C. Tobramycin
D. None of the above

(17) The route of administration of aminoglycosides includes but except?


A. Intrathecal
B. Intramuscular
C. Intravenous
D. Orally

(18) Chloramphenicol is a bacteriostatic which can cause bone marrow suppression?


TRUE OR FALSE?

(19) All but none is an example of factors that contribute to antibiotics misuse EXCEPT
A. Inappropriate clinical tests
B. inappropriate specimen selection and collection
C. A & B above
D. None of the above

(20) The following are example of side effects of aminoglycosides Except?


A. Ototoxicity
B. Nephrotoxicity
C. A ONLY
D. A&B ONLY

PART II THEORY QUESTIONS (SHORT ESSAY ANSWERS)


Q1 (A). Explain briefly differentiate between Bactericidal and Bacteriostatic
antimicrobials, mention three examples of drugs from each.
Q1 (B). Discuss the the following and mention one example of drug from each.

(A) BROAD SPECTRUM ANTIBIOTICS


(B) NARROW SPECTRUM ANTIBIOTICS
(C) CEPHALOSPORINES
(D) AMINOGLYCOSIDES
(E) QUINOLONES
Q2 (A). Distinguish clearly with example difference between
CHEMOTHERAPEUTICS & ANTIBIOTICS

Q2 (B). Mention five most common ideal Properties of antibiotics.


Q3 (A). What are different generations of cephalosporines, Give example of one drug
from each generation

Q3 (B). Mention the route of administration and some side effects of aminoglycosides

BEST OF LUCK!!!

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