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Predict Prostate

This document provides a tool for men without metastatic prostate cancer to evaluate treatment options, including conservative management and radical treatment, in consultation with their doctor. It includes input fields for patient data and presents survival estimates and potential harms associated with each treatment option. Additionally, it offers resources for further information and support related to prostate cancer treatment.

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alexianwhite
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0% found this document useful (0 votes)
17 views1 page

Predict Prostate

This document provides a tool for men without metastatic prostate cancer to evaluate treatment options, including conservative management and radical treatment, in consultation with their doctor. It includes input fields for patient data and presents survival estimates and potential harms associated with each treatment option. Additionally, it offers resources for further information and support related to prostate cancer treatment.

Uploaded by

alexianwhite
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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We recommend that % Print

patients use this tool in ! Settings

consultation with their


doctor.
This tool is only for use
in men without
metastatic disease
where conservative
management and
radical treatment are
both options being
considered.

Reset

Age at
" diagnosis – 59 +

" PSA (ng/ml) – 5.2 +

" Clinical T stage 1 2 3 4

Hospital
" admission in No Yes
last 2 years?

" BRCA Negative or Untested Positive

" Ethnic Origin Please click on the info button

Histological
" grade group 1 2 3 4 5

" Gleason score 3+3 3+4 4+3 8 9 or 10

Biopsy data
" available? No Yes

Biopsy cores
" taken – 8 +

Biopsy cores taken from a MRI directed


target site are considered as 1 core
regardless of the number of biopsy
cores taken. See examples and FAQs.
Biopsy cores
with any
" prostate – 3 +
cancer in
Biopsy cores taken from a MRI directed
target site are considered as 1 core
regardless of the number of biopsy
cores taken. See examples and FAQs.
Is there an
intra-ductal
carcinoma or
invasive
" cribriform No Yes Unknown
component
reported in the
biopsies?

# This tool does not account for intra-


ductal carcinoma or invasive cribriform
component. If you're unsure use the
data with caution and please consult
your medical professional.
Has the cancer
" spread No Yes Unknown
(metastasis)?

Results
Charts Icons Curves Table

Texts

Treatment
" Regime Conservative Radical

This graph shows the percentage of men


surviving at 10 and 15 years. These results are
based on the inputs and treatments you
selected
Overall Survival
100% 100%
88% survive
90%
at least 10 90%
80% years 73% survive
80%
at least 15
70% years 70%
60% 60%
50% 50%

40% 40%
30% 30%

20% 20%

10% 10%
0% 0%
10 15
years after diagnosis

Survival excluding deaths from prostate


cancer

Initial conservative management

Important
These results are estimates based on data
from men with similar characteristics.
There are other important factors which
affect outcomes. Your specialist will help
you put these results in context.

$ Scroll down for potential harms

Potentially permanent harms of


Conservative management

Radical prostatectomy

Radical Radiotherapy
The following estimates are not individualised to you
or your local treatment centre. Your local team may
have data specific to your centre which you can ask
about.

If you are in the UK, centre by centre provider


outcomes are provided by the National Prostate
Cancer Audit which you may find useful:
https://www.npca.org.uk/provider-results/.

Erectile dysfunction
Defined as: 'Erections not firm enough for
intercourse'
Percentages shown include men who may already have this
problem before any treatment is given

With conservative management (men who did not


subsequently change to radical treatment), about 66 in 100

men have this issue after 3 6 9 12 years.

66%

With radical prostatectomy (surgery), about 84 in 100 men

have this issue after 3 6 9 12 years.

84%

With radical radiotherapy (external beam), about 73 in 100

men have this issue after 3 6 9 12 years.

73%

Estimates for erectile dysfunction have been taken from


the UK-based Prostate Testing for Cancer and Treatment
(ProtecT) trial. The full research can be read here:
https://evidence.nejm.org/doi/10.1056/EVIDoa2300018

Incontinence
Defined as: 'Use of 1 or more pads per day in the
past 4 weeks and assuming this problem does not
exist before treatment'
With conservative management (men who did not
subsequently change to radical treatment), about 2 in 100

men have this issue after 3 6 9 12 years.

2%

With radical prostatectomy (surgery), about 17 in 100 men

have this issue after 3 6 9 12 years.

17%

With radical radiotherapy (external beam), about 4 in 100

men have this issue after 3 6 9 12 years.

4%

Estimates for incontinence have been taken from the UK-


based Prostate Testing for Cancer and Treatment
(ProtecT) trial. The full research can be read here:
https://evidence.nejm.org/doi/10.1056/EVIDoa2300018

Bowel issues
Defined as: 'Bloody stools about half the time or
more frequently'
With conservative management, about 1 in 100 men have this

issue after 3 6 9 12 years.

1%

With radical prostatectomy (surgery), about 1 in 100 men

have this issue after 3 6 9 12 years.

1%

With radical radiotherapy (external beam), about 6 in 100

men have this issue after 3 6 9 12 years.

6%

Estimates for bowel issues have been taken from the UK-
based Prostate Testing for Cancer and Treatment
(ProtecT) trial. The full research can be read here:
https://evidence.nejm.org/doi/10.1056/EVIDoa2300018

More Information
The following websites provide excellent advice
and information on treatments and their
potential harms:
About treatments:

Cancer research UK
NHS
About potential harms:

Radical prostatectomy
Radiotherapy
Further advice and support:

Macmillan
Prostate Cancer UK
NHS Choices

Looking for advice?


See the FAQs

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