Fred Hutchinson Cancer Center

The Fred Hutchinson Cancer Center, formerly

Fred Hutchinson Cancer Center
known as the Fred Hutchinson Cancer Research
Center and also known as Fred Hutch or The Hutch,
is a cancer research institute established in 1975 in
Seattle, Washington.[2][3]
Predecessor Fred Hutchinson Cancer
Research Center Seattle

History Cancer Care Alliance

Formation 1975
The center grew out of the Pacific Northwest Research Type Nonprofit organization
Foundation, founded in 1956 by William B. Headquarters
Seattle, Washington, U.S.
Hutchinson (1909–1997). The Foundation was
dedicated to the study of heart surgery, cancer, and Leader Thomas Lynch Jr., M.D.

diseases of the endocrine system. Hutchinson's Budget $654.62 million (2020)[1]

younger brother Fred (1919–1964) was a major league Website fredhutch.org (https://www.fre
pitcher and manager who died of lung cancer at age 45. dhutch.org)
The next year, William Hutchinson established the
Fred Hutchinson Cancer Research Center as a division of the
Pacific Northwest Research Foundation.[2]

In 1972, with the help of Senator Warren G. Magnuson, PNRF

received federal funding under the National Cancer Act of 1971 to
create in Seattle one of the 15 new NCI-designated Cancer Centers
aimed at conducting basic research[4] called for under 1971 Act;
the Fred Hutchinson Cancer Research Center became independent The center's South Lake Union
1972 and its building opened three years later campus as seen from the Space
in 1975.[2][5][6][7][8]: 3, 5 The center was named an NCI-designated Needle
Comprehensive Cancer Center in 1976.[9]

In 1998, the center formed the Seattle Cancer Care Alliance

(SCCA), a separate nonprofit corporation,[10] with University of
Washington School of Medicine (UW Medicine), and Seattle
Children's. This solidified the center's reach into clinical care and
was essential for it retaining its NCI comprehensive center
designation;[11] the designation was extended to the center's
consortium including the SCCA in 2003.[9] SCCA's outpatient
clinic first opened in January 2001.[11]
The center's steam plant building
In 2001, The Seattle Times published a series of articles alleging
that investigators at the center (including the center's co-founder
E. Donnall Thomas) were conducting unethical clinical studies on cancer patients. The paper alleged that
in two cancer studies conducted in the 1980s and early 1990s, patients were not informed about all the
risks of the study, nor about the study doctors' financial interest in study outcome. The paper also alleged
that this financial interest may have contributed to the doctors' failure to halt the studies despite evidence
that patients were dying sooner and more frequently than expected.[12] In response, the center formed a
panel of independent experts to review its existing research practices, leading to adoption of new conflict-
of-interest rules.[13]

In 2010 Lawrence Corey was appointed as the fourth President, following the retirement of Lee Hartwell.
He was followed by Gary Gilliland in 2015 as president, who led the institute until 2020.[14][15][16] Under
his leadership the center announced that it would expand into the former Lake Union steam plant, which
previously housed ZymoGenetics.[17] The move was completed in October 2020.[18] In February 2020,
Thomas J. Lynch Jr. took over as director.[19]

The year 2014 saw the organization adopt its longtime local nickname, "Fred Hutch", as its official name
as part of a rebranding.[20]

On April 1, 2022, Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance (SCCA)
merged to form Fred Hutchinson Cancer Center, a unified adult cancer research and care center that is
clinically integrated with University of Washington (UW) Medicine and UW Medicine's cancer
program.[21]

Notable faculty
The center has employed three recipients of the Nobel Prize in Physiology or Medicine:

Linda B. Buck, who received the award in 2004 for solving many details of the olfactory
system;[22] and
Leland H. Hartwell, who received the honor in 2001 for his discoveries regarding the
mechanisms that control cell division.[23] After retiring from leading the center in 2010,
Hartwell left to join Arizona State University.[24] and
E. Donnall Thomas, who received the award in 1990 for his pioneering work in bone-marrow
transplantation and who died in 2012;[25][26]

Commercialization
The center is active in technology transfer. In 2013, it was one of the top ten biomedical research
institutions in the field (excluding universities); it made 18 new deals with companies to develop
inventions made at the center, and earned $10,684,882 in income from past deals it had signed.[27] Most
notably, Juno Therapeutics, a company developing CAR-T immunotherapy for cancer and that raised
$314 million in venture capital investments and had a $265 million initial public offering in 2014, was
started based on inventions made at the center.[28] As of 2015, about twenty companies had been started
based on center inventions since 1975, including Immunex and Icos.[28]

Campus
The institute's main campus consists of 13 buildings that are on fifteen acres (6.1 ha) in the South Lake
Union neighborhood of Seattle.[29]

In 1987, the center began exploring possible new homes to replace its 9-building campus on First Hill
that it was set to outgrow.[30][31] A site in the South Lake Union neighborhood, envisioned by the city as a
future high-tech and biotechnology hub,[32] was chosen in September 1988 after a deal to move to
Fremont fell through earlier that year.[33][34] The first phase of the campus, designed by firm Zimmer
Gunsul Frasca Partnership,[35] began construction in 1991 and opened on June 1, 1993, in a ceremony
that included the burying of a time capsule set to open in 2093.[36][37]

The campus is accessible via the Mercer Street exit of Interstate 5 as well as several public transportation
routes, including the South Lake Union Streetcar.[38]

See also
Hutch Award
Uganda Program on Cancer and Infectious Diseases

References
1. "Financial Summaries & Impact Reporting" (https://www.fredhutch.org/en/about/about-the-h
utch/accountability-impact/financial-summaries-and-impact-reporting.html). Fred Hutch
Cancer Research Center. Retrieved April 15, 2021.
2. Louis Fiset, December 30, 2004 for HistoryLink: The Free, Online Encyclopedia of
Washington State History Hutchinson, Dr. William B. (1909–1997) (http://www.historylink.or
g/index.cfm?DisplayPage=output.cfm&file_id=7183)
3. "Mission Statement" (https://web.archive.org/web/20120120134200/http://www.fhcrc.org/abo
ut/mission.html). Fred Hutchinson Cancer Research Center. Archived from the original (htt
p://fhcrc.org/about/mission.html) on January 20, 2012. Retrieved August 6, 2009.
4. Simone JV. Understanding cancer centers. J Clin Oncol. 2002 Dec 1;20(23):4503-7.
PMID 12454105 (https://pubmed.ncbi.nlm.nih.gov/12454105)
5. "Center dedication Friday" (https://news.google.com/newspapers?id=UMopAAAAIBAJ&sjid=
yvgDAAAAIBAJ&pg=6987%2C853330). Spokane Daily Chronicle. (Washington). AP.
September 2, 1975. p. 6.
6. Jane Sanders for the University of Washington Libraries. 1987 Essay: A Legacy of Public
Service (https://content.lib.washington.edu/jacksonweb/essay.html)
7. Melissa Allison for the Seattle Times. October 20, 2012 Obituary: E. Donnall Thomas, Nobel
winner for bone-marrow transplant advances (http://www.seattletimes.com/business/e-donn
all-thomas-nobel-winner-for-bone-marrow-transplant-advances/)
8. US Government Accounting Office. March 17, 1976. Comprehensive Cancer Centers: Their
Locations and Role (http://gao.gov/assets/120/116268.pdf)
9. NCI Fred Hutchinson/University of Washington Cancer Consortium (https://www.cancer.gov/
research/nci-role/cancer-centers/find/fredhutchcrc) Page access June 27, 2015
10. Washington State Hospital Association Hospital Details: Seattle Cancer Care Alliance (http
s://www.wsha.org/hospitalDetail.cfm?HID=142) Archived (https://web.archive.org/web/20150
630155433/https://www.wsha.org/hospitalDetail.cfm?HID=142) June 30, 2015, at the
Wayback Machine Page accessed June 27, 2015
11. BusinessWire October 24, 2012 Fitch Affirms Seattle Cancer Care Alliance (WA) Rev Bonds
at A+; Outlook Stable (http://www.businesswire.com/news/home/20121024006661/en/Fitch-
Affirms-Seattle-Cancer-Care-Alliance-WA#.VY8hnhNVhBc)
12. "Uninformed Consent" (http://seattletimes.nwsource.com/uninformed_consent/). The Seattle
Times. 2001.
13. Doughton, Sandi (August 4, 2009). "Hutch leader Lee Hartwell guided center's ride to top,
will retire next June" (http://seattletimes.nwsource.com/html/localnews/2009593731_hartwell
04m.html). The Seattle Times.
14. "Lawrence Corey, infectious disease expert, new Hutchinson Center President" (http://www.
seattlepi.com/local/article/Lawrence-Corey-infectious-disease-expert-new-897269.php).
Seattle Post-Intelligencer. July 29, 2010. Retrieved July 4, 2011.
15. Seattle Times Staff. November 20, 2014 "Genetics expert named director, president of Fred
Hutch" (http://www.seattletimes.com/seattle-news/genetics-expert-named-director-president-
of-fred-hutch/)
16. "D. Gary Gilliland, M.D., Ph.D." (https://www.fredhutch.org/en/faculty-lab-directory/gilliland-g
ary.html)
17. Romano, Benjamin (June 11, 2018). "Hutch cancer center will put labs in Seattle's historic
Lake Union steam plant" (https://www.seattletimes.com/business/technology/hutch-cancer-c
enter-will-put-labs-in-seattles-historic-lake-union-steam-plant/). The Seattle Times. Archived
(https://web.archive.org/web/20200518042224/https://www.seattletimes.com/business/techn
ology/hutch-cancer-center-will-put-labs-in-seattles-historic-lake-union-steam-plant/) from the
original on May 18, 2020.
18. "Fred Hutch completes move-in of Lake Union Steam Plant" (https://www.fredhutch.org/en/n
ews/releases/2020/10/fred-hutch-completes-move-in-of-lake-union-steam-plant.html).
October 15, 2020.
19. "Fred Hutch names Dr. Thomas J. Lynch Jr. As new president and director" (https://www.fred
hutch.org/en/news/releases/2020/01/fred-hutch-names-dr--thomas-j--lynch-jr--as-new-presid
ent-and-director.html). January 7, 2020.
20. Vit, Armin (November 12, 2014). "New Name, Logo, and Identity for Fred Hutch by Hornall
Anderson" (https://web.archive.org/web/20141115215703/https://www.underconsideration.c
om/brandnew/archives/new_name_logo_and_identity_for_fred_hutch_by_hornall_anderson.
php). Archived from the original (https://www.underconsideration.com/brandnew/archives/ne
w_name_logo_and_identity_for_fred_hutch_by_hornall_anderson.php) on November 15,
2014.
21. "Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance, Seattle Children's
and UW Medicine Complete Restructure of Partnership" (https://www.fredhutch.org/en/new
s/releases/2022/04/fred-hutchinson-cancer-research-center--seattle-cancer-care-alli.html).
April 2022.
22. "Medicine 2004" (http://nobelprize.org/nobel_prizes/medicine/laureates/2004/).
nobelprize.org. Retrieved March 29, 2009.
23. "Medicine 2001" (http://nobelprize.org/nobel_prizes/medicine/laureates/2001/).
nobelprize.org. Retrieved March 29, 2009.
24. Luke Timmerman for Xconomy. September 20, 2010 Lee Hartwell, at 70, Tackles
Personalized Medicine, Education in Latest Career Phase (http://www.xconomy.com/seattle/
2010/09/20/lee-hartwell-at-70-tackles-personalized-medicine-education-in-latest-career-pha
se/)
25. Appelbaum, Frederick R. (2012). "E. Donnall Thomas (1920–2012)" (https://doi.org/10.112
6%2Fscience.1232395). Science. 338 (6111): 1163. Bibcode:2012Sci...338.1163A (https://u
i.adsabs.harvard.edu/abs/2012Sci...338.1163A). doi:10.1126/science.1232395 (https://doi.o
rg/10.1126%2Fscience.1232395). PMID 23197524 (https://pubmed.ncbi.nlm.nih.gov/23197
524). S2CID 206546435 (https://api.semanticscholar.org/CorpusID:206546435).
26. "Medicine 1990" (http://nobelprize.org/nobel_prizes/medicine/laureates/1990/).
nobelprize.org. Retrieved March 29, 2009.
27. Brady Huggett. Top US universities and institutes for life sciences in 2013 (http://www.natur
e.com/nbt/journal/v32/n11/pdf/nbt.3066.pdf) Nature Biotechnology 32(11):1085
28. Annie Zak for the Puget Sound Business Journal, February 13, 2015 Fred Hutch and its
amazing spinoff machine (http://www.bizjournals.com/seattle/print-edition/2015/02/13/fred-h
utch-and-its-amazing-spinoff-machine.html)
29. "Our Sustainable Campus" (https://web.archive.org/web/20190626175155/http://www.fredhu
tch.org/en/about/sustainable-campus.html). Fred Hutchinson Cancer Research Center.
Archived from the original (https://www.fredhutch.org/en/about/sustainable-campus.html) on
June 26, 2019. Retrieved December 17, 2015.
30. Balter, Joni (September 27, 1987). "Growing Fred Hutchinson Cancer Center may move" (ht
tp://infoweb.newsbank.com/resources/doc/nb/news/0EB532805223E582?p=AMNEWS).
The Seattle Times. p. A1. Retrieved December 17, 2015 – via NewsBank.
31. Levy, Nat (December 17, 2015). "Why and how the Hutch moved to SLU" (http://www.djc.co
m/news/re/12084595.html). Seattle Daily Journal of Commerce. Retrieved December 17,
2015.
32. Lilly, Dick (June 20, 1993). "Firms Moving Quicker than Commons Plan" (http://infoweb.new
sbank.com/resources/doc/nb/news/0EB5367ECCF6026A?p=AMNEWS). The Seattle
Times. p. B1. Retrieved December 17, 2015 – via NewsBank.
33. Angelos, Constantine (September 30, 1988). "Hutchinson Center approves new site - Board
OK's plan to buy Lake Union" (http://infoweb.newsbank.com/resources/doc/nb/news/0EB53
3064DAF6CD0?p=AMNEWS). The Seattle Times. p. A1. Retrieved December 17, 2015 –
via NewsBank.
34. Nogaki, Sylvia (June 25, 1988). "Hutchinson Division's move canceled - Grants make N.
end site too small" (http://infoweb.newsbank.com/resources/doc/nb/news/0EB532E509B3A4
C3?p=AMNEWS). The Seattle Times. p. A10. Retrieved December 17, 2015 – via
NewsBank.
35. King, Marsha (July 28, 1991). "In This Space At This Time -- ZGF's Organic Style Gives
Birth To Buildings That Fit" (https://archive.seattletimes.com/archive/19910728/1296834/in-t
his-space-at-this-time----zgfs-organic-style-gives-birth-to-buildings-that-fit). The Seattle
Times. Retrieved December 17, 2015.
36. Woodward, Kristen (February 2015). "40 things you didn't know about Fred Hutch" (https://w
eb.archive.org/web/20151222080024/https://www.fredhutch.org/en/news/hutch-magazine/2
015-02/40-things-you-didn-t-know-about-fred-hutch.html). Hutch Magazine. Fred Hutchinson
Cancer Research Center. Archived from the original (https://www.fredhutch.org/en/news/hut
ch-magazine/2015-02/40-things-you-didn-t-know-about-fred-hutch.html) on December 22,
2015. Retrieved December 17, 2015.
37. "Hutchinson Dedicates a New Lab Building". The Seattle Times. June 2, 1993. p. B2.
38. Campus Buildings & Destinations (https://web.archive.org/web/20210423151400/https://ww
w.fredhutch.org/content/dam/public/contact-us/Visit-Us/FRED_HUTCH_CAMPUS_MAP_onli
ne.pdf) (PDF) (Map). Fred Hutchinson Cancer Research Center. Archived from the original
(https://www.fredhutch.org/content/dam/public/contact-us/Visit-Us/FRED_HUTCH_CAMPUS
_MAP_online.pdf) (PDF) on April 23, 2021. Retrieved December 17, 2015.

Further reading
Carl Elliott (2024). "Chapter 4: The Hutch". The Occasional Human Sacrifice (https://wwnort
on.com/books/9781324065500). W. W. Norton & Company. ISBN 978-1-324-06550-0.
 OL 51042411M (https://openlibrary.org/books/OL51042411M). Wikidata Q125974314.

External links
Fred Hutchinson Cancer Research Center Web site (http://www.fredhutch.org)
Fred Hutch Biomedical Data Science Wiki (https://sciwiki.fredhutch.org)

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