SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Dissolvine Na2

Version 2 Revision Date 19.12.2019 Print Date 22.12.2020 GB / EN

SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE

COMPANY/UNDERTAKING

1.1 Product identifier

Trade name : Dissolvine Na2

Substance name : Ethylenediaminetetraacetic acid, disodium salt

REACH Registration Number : 01-2119486775-20-0000

1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the : Specific use(s): Chelating agent
Substance/Mixture
Specific use(s): Refer to attached exposure
scenario Annex.

1.3 Details of the supplier of the safety data sheet

Company : Nouryon
Functional Chemicals B.V.
Velperweg 76
NL 6824 BM Arnhem
Netherlands

Telephone : +31263664433
Telefax :
E-mail address : sds_chelates@nouryon.com
1.4 Emergency telephone number
Emergency telephone : 24 hours:+31 57 06 79211, CHEMTREC-USA:1-800-424-
number 9300, CHEMTREC outside USA +1-703-527-3887,
CANUTEC-CANADA:1-613-996-6666,
化学事故应急咨询电话： 国家化学事故应急响应中心 +86 532
8388 9090

SECTION 2: HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008)

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Acute toxicity, 4, H332

Specific target organ toxicity - repeated exposure, 2, Respiratory Tract, H373

For the full text of the H-Statements mentioned in this Section, see Section 16.

2.2 Label elements

Labelling (REGULATION (EC) No 1272/2008)
Pictogram :

Signal word : Warning

Hazard statements : H332 Harmful if inhaled.

H373 May cause damage to organs
(Respiratory Tract) through prolonged
or repeated exposure if inhaled.

Precautionary statements : Prevention:

P260 Do not breathe dust or fume.
P271 Use only outdoors or in a well-ventilated
area.
Response:
P304 + P340 + P312 IF INHALED: Remove person to fresh
air and keep comfortable for breathing.
Call a POISON CENTER/doctor if you
feel unwell.
P314 Get medical advice/ attention if you feel
unwell.
Disposal:
P501 Dispose of contents/container in
accordance with local regulation.

Hazardous components which must be listed on the label:

Ethylenediaminetetraacetic acid, disodium salt 139-33-3

2.3 Other hazards

Risk of dust explosion.

No further data available.

PBT and vPvB assessment : This substance/mixture contains no components considered

to be either persistent, bioaccumulative and toxic (PBT), or
very persistent and very bioaccumulative (vPvB) at levels of
0.1% or higher.

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SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances
Common Name : Ethylenediaminetetraacetic acid, disodium salt, dihydrate
Pure substance/mixture : Substance

Hazardous substance

PBT CAS-No.
Classification Concentration
Chemical name vPvB EC-No.
(REGULATION (EC) No 1272/2008) [%]
OEL REACH No.

Ethylenediaminetetraacetic acid, 139-33-3 Acute Tox. 4; H332 >= 90 - < 100

disodium salt 205-358-3 STOT RE 2; H373
01-2119486775-20

For the full text of the H-Statements mentioned in this Section, see Section 16.

REACH - Candidate List of Substances of Very High Concern for Authorisation (Article 59).
Status : Not applicable

SECTION 4: FIRST AID MEASURES

4.1 Description of first aid measures
General advice : Move out of dangerous area.
Consult a physician.
Show this safety data sheet to the doctor in attendance.

If inhaled : Rinse nose and mouth with water.

In case of skin contact : Take off contaminated clothing and shoes immediately.

In case of eye contact : Rinse with plenty of water.

Remove contact lenses.
Protect unharmed eye.
Keep eye wide open while rinsing.
If eye irritation persists, consult a specialist.

If swallowed : Clean mouth with water and drink afterwards plenty of water.
Never give anything by mouth to an unconscious person.
Obtain medical attention.

4.2 Most important symptoms and effects, both acute and delayed
Symptoms : The symptoms and effects are as expected from the hazards
as shown in section 2. No specific product related symptoms
are known.

Risks : Harmful if inhaled.

May cause damage to organs through prolonged or repeated
exposure if inhaled.

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4.3 Indication of any immediate medical attention and special treatment needed
Treatment : Treat symptomatically.

SECTION 5: FIREFIGHTING MEASURES

5.1 Extinguishing media
Suitable extinguishing media : Use extinguishing measures that are appropriate to local
circumstances and the surrounding environment.

5.2 Special hazards arising from the substance or mixture

Specific hazards during : Do not allow run-off from fire fighting to enter drains or water
firefighting / Specific hazards courses.
arising from the chemical Risks of ignition followed by flame propagation or secondary
explosions shall be prevented by avoiding accumulation of
dust, e.g. on floors and ledges.

Combustion products : Nitrogen oxides (NOx)

5.3 Advice for firefighters

Special protective equipment : In the event of fire, wear self-contained breathing apparatus.
for firefighters
Further information : Collect contaminated fire extinguishing water separately. This
must not be discharged into drains.
Fire residues and contaminated fire extinguishing water must
be disposed of in accordance with local regulations.

SECTION 6: ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures
Personal precautions : Use personal protective equipment.
Wear respiratory protection.
Avoid dust formation.
Avoid breathing dust.
Ensure adequate ventilation.

Emergency measures on : Evacuate personnel to safe areas.

accidental release Only qualified personnel equipped with suitable protective
equipment may intervene.
Prevent unauthorised persons entering the zone.

6.2 Environmental precautions

Environmental precautions : Do not flush into surface water or sanitary sewer system.
If the product contaminates rivers and lakes or drains inform
respective authorities.

6.3 Methods and materials for containment and cleaning up

Methods for cleaning up / : Pick up and arrange disposal without creating dust.
Methods for containment Sweep up and shovel.
Keep in suitable, closed containers for disposal.

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6.4 Reference to other sections

For disposal considerations see section 13.
For personal protection see section 8.

SECTION 7: HANDLING AND STORAGE

7.1 Precautions for safe handling
Advice on safe handling : For personal protection see section 8.
Avoid formation of respirable particles.
Do not breathe vapours/dust.
Keep away from heat/sparks/open flames/hot surfaces. No
smoking.
Smoking, eating and drinking should be prohibited in the
application area.
Provide sufficient air exchange and/or exhaust in work rooms.
Dispose of rinse water in accordance with local and national
regulations.

Advice on protection against : Provide appropriate exhaust ventilation at places where dust
fire and explosion is formed.
No sparking tools should be used.

7.2 Conditions for safe storage, including any incompatibilities

Requirements for storage : Prevent unauthorized access.
areas and containers Keep in a dry place.
Store at room temperature in the original container.
Keep container tightly closed.

Other data : No decomposition if stored and applied as directed.

7.3 Specific end use(s)

Specific use(s) : Refer to attached exposure scenario Annex.

SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters
Components with workplace control parameters

Components CAS-No. Value Control Update Basis Form of

parameters exposure
Dust TWA 10 mg/m3 2011-12-01 GB EH40 Inhalable

Further : 44: The COSHH definition of a substance hazardous to health includes dust
information of any kind when present at a concentration in air equal to or greater than 10
mg.m-3 8-hour TWA of inhalable dust or 4 mg.m-3 8-hour TWA of respirable
dust. This means that any dust will be subject to COSHH if people are
exposed to dust above these levels. Some dusts have been assigned
specific WELs and exposure to these must comply with the appropriate
limits.
16: Where no specific short-term exposure limit is listed, a figure three times
the long-term exposure limit should be used.
Dust TWA 4 mg/m3 2011-12-01 GB EH40 Respirable

Further : 44: The COSHH definition of a substance hazardous to health includes dust
information of any kind when present at a concentration in air equal to or greater than 10

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mg.m-3 8-hour TWA of inhalable dust or 4 mg.m-3 8-hour TWA of respirable

dust. This means that any dust will be subject to COSHH if people are
exposed to dust above these levels. Some dusts have been assigned
specific WELs and exposure to these must comply with the appropriate
limits.
16: Where no specific short-term exposure limit is listed, a figure three times
the long-term exposure limit should be used.

ACGIH: American Conference of Governmental Industrial Hygienists

AGW: Arbeitsplatzgrenzwert
BEI: Biological Exposure Index
MAC: Maximum Allowable Concentration
NIOSH: National Institute for Occupational Safety and Health
OEL: OEL: Occupational exposure limit.
STEL: Short term exposure limit
TRGS: Technische Regel für Gefahrstoffe
TWA: Time Weighted Average

Derived No Effect Level (DNEL) according to Regulation (EC) No. 1907/2006

Substance name End Use Exposure Potential health effects Value
routes
Ethylenediaminetetraacetic acid, Workers Inhalation Long-term local effects 1.5 mg/m3
disodium salt
Workers Inhalation Acute local effects 3 mg/m3

Predicted No Effect Concentration (PNEC) according to Regulation (EC) No. 1907/2006

Substance name Environmental Compartment Value
Ethylenediaminetetraacetic acid, disodium salt Fresh water 2.5 mg/l
Marine water 0.25 mg/l
Intermittent water 1.4 mg/l
Soil 0.84 mg/kg dry weight
Sewage treatment plant 50 mg/l

8.2 Exposure controls

Engineering controls
Provide appropriate exhaust ventilation at places where dust is formed.
Personal protective equipment
Respiratory protection : Half mask with a particle filter P2 (EN 143)

Eye protection : Tightly fitting safety goggles

Skin and body protection : Protective suit

Hygiene measures : Handle in accordance with good industrial hygiene and safety
practice.
When using do not eat or drink.
When using do not smoke.
Wash hands before breaks and at the end of workday.

Environmental exposure controls

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General advice : Do not flush into surface water or sanitary sewer system.
If the product contaminates rivers and lakes or drains inform
respective authorities.

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties
Appearance
Form : powder

Colour : white

Odour : odourless

Odour Threshold : Not applicable

Safety data
pH : 4 - 5 1% (water)

Melting point : Decomposes before melting.

Boiling point/boiling range : Not applicable

Flash point : Not applicable

Ignition temperature : >= 200 °C

Method: Auto-ignition of a 5mm dust layer according to EN
50281-2-1

Evaporation rate : Not applicable

Flammability (solid, gas) : Not classified as a flammability hazard

May form combustible dust concentrations in air during
processing, handling or other means.

Flammability (liquids) : Not applicable

Lower explosion limit : >= 40 g/m3

Upper explosion limit : Not applicable

Vapour pressure : Not applicable

Relative vapour density : Not applicable

Relative density : No data available

Bulk density : ca. 700 kg/m3

Water solubility : ca. 100 g/l

Solubility in other solvents : No data available

Partition coefficient: n- : log Pow: < 0

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octanol/water

Auto-ignition temperature : No data available

Decomposition temperature : No data available

Viscosity, dynamic : Not applicable

Viscosity, kinematic : Not applicable

Explosive properties : Not explosive

Oxidizing properties : Not classified as oxidising.

9.2 Other information

This safety datasheet only contains information relating to safety and does not replace any
product information or product specification.

SECTION 10: STABILITY AND REACTIVITY

10.1 Reactivity
Stable under normal conditions.
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
Dust may form explosive mixture in air.

10.4 Conditions to avoid

Conditions to avoid : None known.

10.5 Incompatible materials

Materials to avoid : None known.

10.6 Hazardous decomposition products

Hazardous decomposition : Carbon oxides
products nitrogen oxides (NOx)

Thermal decomposition : No data available

SECTION 11: TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects
Product information:
Acute toxicity : Harmful if inhaled.

Skin corrosion/irritation : Not classified based on available information.

Serious eye damage/eye : Not classified based on available information.

irritation
Respiratory or skin : Respiratory sensitisation: Not classified based on available
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sensitisation information.
Skin sensitisation: Not classified based on available
information.

Germ cell mutagenicity : Not classified based on available information.

Carcinogenicity : Not classified based on available information.

Reproductive toxicity : Not classified based on available information.

STOT - single exposure : Not classified based on available information.

STOT - repeated exposure : May cause damage to organs (Respiratory Tract) through
prolonged or repeated exposure if inhaled.

Aspiration hazard : Not classified based on available information.

Further information : No further data available.

Test result
Acute inhalation toxicity : Acute toxicity estimate : 1.68 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Method: Calculation method

STOT - repeated exposure : Exposure routes: Inhalation

Target Organs: Respiratory Tract
The substance or mixture is classified as specific target organ
toxicant, repeated exposure, category 2.

Toxicology data for the components:

Ethylenediaminetetraacetic acid, disodium salt
Acute toxicity:
Acute oral toxicity : LD50: > 2,000 mg/kg
Species: Rat

Acute inhalation toxicity : LC50 (Rat): > 1 - 5 mg/l

Exposure time: 4 h
Test atmosphere: dust/mist
Method: OECD Test Guideline 412

Skin corrosion/irritation : Species: Rabbit

Result: No skin irritation
Method: OECD Test Guideline 404

Serious eye damage/eye : Species: Rabbit

irritation Result: No eye irritation
Method: OECD Test Guideline 405

Respiratory or skin : Maximisation Test

sensitisation Species: Guinea pig
Result: Does not cause skin sensitisation.
Method: OECD Test Guideline 406

Germ cell mutagenicity

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Genotoxicity in vitro : Result: negative

Method: Mutagenicity (Salmonella typhimurium - reverse
mutation assay)

Genotoxicity in vivo : Chromosome aberration test in vivo

Species: Mouse
Method: OECD Test Guideline 474
Result: negative

Carcinogenicity : Species: Rat

Application Route: Ingestion
Result: Not classified due to data which are conclusive
although insufficient for classification.
Read-across (Analogy)

Reproductive toxicity : Species: Rat

NOAEL:
F1: > 250 mg/kg,
Read-across (Analogy), Information taken from reference
works and the literature.

STOT - single exposure : Based on available data, the classification criteria are not met.

STOT - repeated exposure : Exposure routes: Inhalation

Target Organs: Respiratory Tract
The substance or mixture is classified as specific target organ
toxicant, repeated exposure, category 2.

Aspiration hazard : Not classified due to data which are conclusive although
insufficient for classification.

SECTION 12: ECOLOGICAL INFORMATION

Product information:
Ecotoxicology Assessment
Additional ecological : None known.
information
12.1 Toxicity
Components:
Test result
Ethylenediaminetetraacetic acid, disodium salt
Toxicity to fish : LC50: > 100 mg/l
Exposure time: 96 h
Species: Fish
Read-across (Analogy)

Toxicity to daphnia and other : EC50 (calculated): 140 mg/l

aquatic invertebrates Exposure time: 48 h
Species: Daphnia magna (Water flea)
Method: DIN 38412

Toxicity to bacteria : EC50: > 500 mg/l

Exposure time: 30 min
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Species: activated sludge

Test Type: Respiration inhibition
Method: OECD Test Guideline 209

Toxicity to fish (Chronic : NOEC: > 25.7 mg/l

toxicity) Exposure time: 35 d
Species: Danio rerio (zebra fish)
Test Type: flow-through test
Method: OECD Test Guideline 210
Read-across (Analogy)

Toxicity to daphnia and other : NOEC: > 25 mg/l

aquatic invertebrates Exposure time: 21 d
(Chronic toxicity) Species: Daphnia magna (Water flea)

12.2 Persistence and degradability

Product information:
Biodegradability : Not readily biodegradable, but will degrade after a longer
period.

Components:
Ethylenediaminetetraacetic acid, disodium salt
Biodegradability : Not readily biodegradable, but will degrade after a longer
period.

12.3 Bioaccumulative potential

Product information:
Bioaccumulation : Not expected considering the low log Pow value.

Components:
Ethylenediaminetetraacetic acid, disodium salt
Bioaccumulation : Not expected considering the low log Pow value.

12.4 Mobility in soil

Product information:
Mobility : Adsorption to the solid soil particles is not expected.

Components:
Ethylenediaminetetraacetic acid, disodium salt
Mobility : Adsorption to the solid soil particles is not expected.

12.5 Results of PBT and vPvB assessment

Product information:
PBT and vPvB assessment : This substance/mixture contains no components considered
to be either persistent, bioaccumulative and toxic (PBT), or
very persistent and very bioaccumulative (vPvB) at levels of
0.1% or higher.

Components:
Ethylenediaminetetraacetic acid, disodium salt
PBT and vPvB assessment : This substance is not considered to be a PBT (Persistent,
Bioaccumulation, Toxic)
This substance is not considered to be vPvB (very Persistent
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nor very Bioaccumulating)

12.6 Other adverse effects
Product information:
Biochemical Oxygen : No data available
Demand (BOD)
Components:
Ethylenediaminetetraacetic acid, disodium salt
Biochemical Oxygen : No data available
Demand (BOD)
Chemical Oxygen Demand : 630 mg/g
(COD)

SECTION 13: DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods
Product : Do not dispose of waste into sewer.
Do not contaminate ponds, waterways or ditches with
chemical or used container.
Hazardous waste
Dispose of contents/container in accordance with local
regulation.

Contaminated packaging : Empty remaining contents.

Dispose of as unused product.

SECTION 14: TRANSPORT INFORMATION

14.1 UN number
Not regulated as a dangerous good
14.2 Proper shipping name
Not regulated as a dangerous good
14.3 Transport hazard class
Not regulated as a dangerous good
14.4 Packing group
Not regulated as a dangerous good
14.5 Environmental hazards
Not regulated as a dangerous good
14.6 Special precautions for user
Remarks : Not classified as dangerous in the meaning of transport
regulations.

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.

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SECTION 15: REGULATORY INFORMATION

15.1 Safety, health and environmental regulations/legislation specific for the substance or
mixture
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of
major-accident hazards involving dangerous substances.
Not applicable

Notification status
DSL : YES. All components of this product are on the Canadian DSL
AICS : YES. On the inventory, or in compliance with the inventory
ENCS : YES. On the inventory, or in compliance with the inventory
ISHL : YES. On the inventory, or in compliance with the inventory
KECI : YES. On the inventory, or in compliance with the inventory
PICCS : YES. On the inventory, or in compliance with the inventory
IECSC : YES. On the inventory, or in compliance with the inventory
TCSI : YES. On the inventory, or in compliance with the inventory
TSCA : YES. All chemical substances in this product are either listed on the
TSCA Inventory or in compliance with a TSCA Inventory exemption.

For explanation of abbreviation see section 16.

15.2 Chemical safety assessment

Ethylenediaminetetraacetic : A Chemical Safety Assessment has been carried out for this
acid, disodium salt substance.

SECTION 16: OTHER INFORMATION

Full text of H-Statements referred to under sections 2 and 3.

H332 : Harmful if inhaled.
H373 : May cause damage to organs through prolonged or repeated
exposure if inhaled.

Full text of other abbreviations

GB EH40 : UK. EH40 WEL - Workplace Exposure Limits
GB EH40 / TWA : Long-term exposure limit (8-hour TWA reference period)

ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways; ADR - European Agreement concerning the International Carriage of Dangerous
Goods by Road; AICS - Australian Inventory of Chemical Substances; ASTM - American Society
for the Testing of Materials; bw - Body weight; CLP - Classification Labelling Packaging
Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive
Toxicant; DIN - Standard of the German Institute for Standardisation; DSL - Domestic Substances
List (Canada); ECHA - European Chemicals Agency; EC-Number - European Community
number; ECx - Concentration associated with x% response; ELx - Loading rate associated with
x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances
(Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally
Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research
on Cancer; IATA - International Air Transport Association; IBC - International Code for the
Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal
inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of
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Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO -
International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO -
International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50
- Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test
population (Median Lethal Dose); MARPOL - International Convention for the Prevention of
Pollution from Ships; n.o.s. - Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect
Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect
Loading Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic
Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention;
PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of
Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship;
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council
concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID -
Regulations concerning the International Carriage of Dangerous Goods by Rail; SADT - Self-
Accelerating Decomposition Temperature; SDS - Safety Data Sheet; SVHC - Substance of Very
High Concern; TCSI - Taiwan Chemical Substance Inventory; TRGS - Technical Rule for
Hazardous Substances; TSCA - Toxic Substances Control Act (United States); UN - United
Nations; vPvB - Very Persistent and Very Bioaccumulative

Further information
The information provided in this Safety Data Sheet is correct to the best of our knowledge,
information and belief at the date of its publication. The information given is designed only as a
guidance for safe handling, use, processing, storage, transportation, disposal and release and
is not to be considered a warranty or quality specification. The information relates only to the
specific material designated and may not be valid for such material used in combination with
any other materials or in any process, unless specified in the text.

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Annex :

1. Industrial formulation, Formulation & (re)packing of substances and mixtures,

Dustiness: Low

2. Industrial formulation, Formulation & (re)packing of substances and mixtures,

Dustiness: Medium

3. Industrial use, Dustiness: Low

4. Industrial use, Dustiness: Medium

5. Industrial use, Use in spraying formulations.

6. Professional use, Use in spraying formulations.

7. Professional use, Use in non-spraying formulations., Dustiness: Low

8. Professional use, Use in non-spraying formulations., Dustiness: Medium

9. Industrial use, Building and construction work, Dustiness: Low

10. Industrial use, Building and construction work, Dustiness: Medium

11. Professional use, Building and construction work, Dustiness: Low

12. Professional use, Building and construction work, Dustiness: Medium

13. Consumer use

14. Consumer use, Used for personal care products

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1. Short title of Exposure Scenario: Industrial formulation, Formulation & (re)packing

of substances and mixtures, Dustiness: Low

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC2, ERC3: Formulation of preparations, Formulation in
materials
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC4: Use in batch and other process (synthesis) where
opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
PROC19: Manual activities involving hand contact

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC2: Formulation

of preparations

Amount used
Regional use tonnage : 8100 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 100 %
region:
Fraction of Regional tonnage used : 7%
locally:
Maximum daily site tonnage : 1956 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

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Other given operational conditions affecting environmental exposure

Number of emission days per year : 300
Emission or Release Factor: Air : 0.25 %
Emission or Release Factor: Water : 2 %
Emission or Release Factor: Soil : 0.01 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness, Liquid mixture
Vapour pressure : < 0.01 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <= 8 h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

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Automated process with (semi) closed systems

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Drain down and flush
system prior to equipment opening or maintenance.

2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Batch process, Open systems

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems., Drain down and flush
system prior to equipment opening or maintenance.

2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Batch process, Mixing operations (open

systems)

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems., Drain down and flush
system prior to equipment opening or maintenance.

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

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2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Material transfers, Non-dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Material transfers, Dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : Drum and small package filling

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

No specific measures identified., Use long handled tools., Avoid splashing.

2.13 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

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or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

No specific measures identified.

2.14 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Technical conditions and measures

No specific measures identified.

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC8d EUSES Fresh water 2.00 mg/L 0.8
EUSES Marine water 0.2 mg/L 0.799
EUSES Sewage 19.6 mg/L 0.391
treatment
plant
EUSES Soil 0.03 mg/kg 0.039
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC1 ECETOC TRA Long term 0.01 mg/m³ 0.01
inhalation
Long term
dermal
PROC2 ECETOC TRA Long term 0.01 mg/m3 0.01
inhalation
Long term
dermal
PROC3 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
Long term
dermal
PROC4 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term

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dermal
PROC5 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term
dermal
PROC6 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
Long term
dermal
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term
dermal
PROC8b ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
Long term
dermal
PROC9 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
Long term
dermal
PROC10 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term
dermal
CS100 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
Long term
dermal
PROC19 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term
dermal

CS100: Production or preparation or articles by tabletting, compression, extrusion or pelletisation

ERC8d: Wide dispersive outdoor use of processing aids in open systems
PROC1: Use in closed process, no likelihood of exposure
PROC10: Roller application or brushing
PROC19: Manual activities involving hand contact
PROC2: Use in closed, continuous process with occasional controlled exposure
PROC3: Use in closed batch process (synthesis or formulation)
PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities
PROC9: Transfer of substance or preparation into small containers (dedicated filling line,
including weighing)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

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For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Industrial formulation, Formulation & (re)packing

of substances and mixtures, Dustiness: Medium

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC2, ERC3: Formulation of preparations, Formulation in
materials
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC4: Use in batch and other process (synthesis) where
opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
CS100: Production or preparation or articles by tabletting,
compression, extrusion or pelletisation
PROC19: Manual activities involving hand contact

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC2: Formulation

of preparations

Amount used
Regional use tonnage : 8100 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 100 %
region:
Fraction of Regional tonnage used : 7%
locally:
Maximum daily site tonnage : 1956 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
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Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 300
Emission or Release Factor: Air : 0.25 %
Emission or Release Factor: Water : 2 %
Emission or Release Factor: Soil : 0.01 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

Automated process with (semi) closed systems

Technical conditions and measures

No specific measures identified.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

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2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Batch process, Open systems

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

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2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Non-dedicated facility, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Dedicated facility, Material transfers

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
90 %)
<25%, No specific measures identified.

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : General exposures, Dedicated facility, Drum and small

package filling, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

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Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.13 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <25%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
In case no LEV is present, a suitable respiratory protection with adequate effectiveness is required,
Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a
measure): 80 %)

2.14 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a
measure): 90 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC8d EUSES Fresh water 2.00 mg/L 0.8
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EUSES Marine water 0.2 mg/L 0.799

EUSES Sewage 19.6 mg/L 0.391
treatment
plant
EUSES Soil 0.03 mg/kg 0.039
dry weight

ERC8d: Wide dispersive outdoor use of processing aids in open systems

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Industrial use, Dustiness: Low

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC4, ERC5, ERC6a, ERC6b, ERC6c, ERC6d, ERC7: Use of
non-reactive processing aid at industrial site (no inclusion into
or onto article), Industrial use resulting in inclusion into or onto
a matrix, Use of intermediate, Use of reactive processing aid
at industrial site (no inclusion into or onto article), Industrial
use of monomers for manufacture of thermoplastics, Industrial
use of process regulators for polymerisation processes in
production of resins, rubbers, polymers, Industrial use of
substances in closed systems
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC4: Use in batch and other process (synthesis) where
opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
CS100: Production or preparation or articles by tabletting,
compression, extrusion or pelletisation
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal
working operations
PROC18: General greasing/lubrication at high kinetic energy
conditions
PROC19: Manual activities involving hand contact
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC4: Use of non-
reactive processing aid at industrial site (no inclusion into or onto article)

Amount used
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Regional use tonnage : 5.87 ton(s)/year

(tonnes/year):
Fraction of EU tonnage used in : 0.07 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 39.13 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 150
Emission or Release Factor: Air : 0.001 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 0.1 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Industrial use

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.01 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <= 8 h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

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2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

Automated process with (semi) closed systems

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Drain down and flush
system prior to equipment opening or maintenance.

2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Batch process, Open systems

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems., Drain down and flush
system prior to equipment opening or maintenance.

2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Batch process, Mixing operations (open

systems)

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Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems., Drain down and flush
system prior to equipment opening or maintenance.

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Material transfers, Non-dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Material transfers, Dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : Drum and small package filling

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

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2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

No specific measures identified., Use long handled tools., Avoid splashing.

2.13 Contributing scenario controlling worker exposure for: PROC13: Treatment of

articles by dipping and pouring

Activity : Dipping, immersion and pouring, General exposures (open

systems)

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

2.14 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

No specific measures identified.

2.15 Contributing scenario controlling worker exposure for: PROC15: Use as

laboratory reagent

Activity : General exposures, Laboratory activities, Small scale, Manual

Technical conditions and measures

No specific measures identified.

2.16 Contributing scenario controlling worker exposure for: PROC17: Lubrication at

high energy conditions in metal working operations

Activity : General exposures, Operation and lubrication of high energy

open equipment

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
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Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

2.17 Contributing scenario controlling worker exposure for: PROC18: General

greasing/lubrication at high kinetic energy conditions

Activity : General exposures

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

2.18 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Technical conditions and measures

No specific measures identified.

2.19 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Product characteristics
Physical Form (at time of use) : solid

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC4 EUSES Fresh water 2 mg/L 0.796
Marine water 0.2 mg/L 0.794
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Sewage 19.6 mg/L 0.391

treatment
plant
Soil 0.03 mg/kg 0.032
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC1 ECETOC TRA Long term 0.01 mg/m³ 0.01
inhalation
PROC2 ECETOC TRA Long term 0.01 mg/m3 0.01
inhalation
PROC3 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC4 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC5 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC6 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8b ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC9 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC10 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC13 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
CS100 ECETOC TRA Long term 0.1 mg/m3 0.07
inhalation
PROC15 ECETOC TRA Long term 0.1 mg/m3 0.07
inhalation
PROC17 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC18 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC19 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC21 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation

CS100: Production or preparation or articles by tabletting, compression, extrusion or pelletisation

ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
PROC1: Use in closed process, no likelihood of exposure
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal working operations
PROC18: General greasing/lubrication at high kinetic energy conditions
PROC19: Manual activities involving hand contact
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PROC2: Use in closed, continuous process with occasional controlled exposure

PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC3: Use in closed batch process (synthesis or formulation)
PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities
PROC9: Transfer of substance or preparation into small containers (dedicated filling line,
including weighing)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Industrial use, Dustiness: Medium

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC4, ERC5, ERC6a, ERC6b, ERC6c, ERC6d, ERC7: Use of
non-reactive processing aid at industrial site (no inclusion into
or onto article), Industrial use resulting in inclusion into or onto
a matrix, Use of intermediate, Use of reactive processing aid
at industrial site (no inclusion into or onto article), Industrial
use of monomers for manufacture of thermoplastics, Industrial
use of process regulators for polymerisation processes in
production of resins, rubbers, polymers, Industrial use of
substances in closed systems
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC4: Use in batch and other process (synthesis) where
opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
CS100: Production or preparation or articles by tabletting,
compression, extrusion or pelletisation
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal
working operations
PROC18: General greasing/lubrication at high kinetic energy
conditions
PROC19: Manual activities involving hand contact
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC4: Use of non-
reactive processing aid at industrial site (no inclusion into or onto article)

Amount used
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Regional use tonnage : 5.87 ton(s)/year

(tonnes/year):
Fraction of EU tonnage used in : 0.07 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 39.13 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 150
Emission or Release Factor: Air : 0.001 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 0.1 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Industrial use

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, medium dustiness
Vapour pressure : < 0.01 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <= 8 h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

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2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

Automated process with (semi) closed systems

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Batch process, Open systems

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

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2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Non-dedicated facility, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

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2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Dedicated facility, Material transfers

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
90 %)
<25%, No specific measures identified.

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : General exposures, Dedicated facility, Drum and small

package filling, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

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2.13 Contributing scenario controlling worker exposure for: PROC13: Treatment of

articles by dipping and pouring

Activity : General exposures, Dipping, immersion and pouring

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

2.14 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
When concentration is:, <25%, No specific measures identified.

2.15 Contributing scenario controlling worker exposure for: PROC15: Use as

laboratory reagent

Activity : General exposures, Laboratory activities, Manual, Small scale

Technical conditions and measures

No specific measures identified.

2.16 Contributing scenario controlling worker exposure for: PROC17: Lubrication at

high energy conditions in metal working operations

Activity : General exposures, Operation and lubrication of high energy

open equipment

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

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2.17 Contributing scenario controlling worker exposure for: PROC18: General

greasing/lubrication at high kinetic energy conditions

Activity : General exposures

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 90 %)

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.18 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a
measure): 90 %)

2.19 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

When concentration is:, >5%, Provide extraction ventilation at points where emissions occur.
(Effectiveness (of a measure): 90 %)
When concentration is:, <5%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC4 EUSES Fresh water 2 mg/L 0.796
Marine water 0.2 mg/L 0.794

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Sewage 19.6 mg/L 0.391

treatment
plant
Soil 0.03 mg/kg 0.032
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC1 ECETOC TRA Long term 0.01 mg/m³ 0.01
inhalation
PROC2 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC3 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC4 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC5 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC6 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8b ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC9 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC10 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC13 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
CS100 ECETOC TRA Long term 0.2 mg/m3 0.13
inhalation
PROC15 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC17 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC18 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC19 ECETOC TRA Long term 0.5 mg/m3 0.33
inhalation
PROC21 ECETOC TRA Long term 0.6 mg/m³ 0.4
inhalation

CS100: Production or preparation or articles by tabletting, compression, extrusion or pelletisation

ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
PROC1: Use in closed process, no likelihood of exposure
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal working operations
PROC18: General greasing/lubrication at high kinetic energy conditions
PROC19: Manual activities involving hand contact
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PROC2: Use in closed, continuous process with occasional controlled exposure

PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC3: Use in closed batch process (synthesis or formulation)
PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities
PROC9: Transfer of substance or preparation into small containers (dedicated filling line,
including weighing)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Industrial use, Use in spraying formulations.

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC5, ERC6a, ERC6b, ERC6c, ERC6d, ERC7: Industrial use
resulting in inclusion into or onto a matrix, Use of intermediate,
Use of reactive processing aid at industrial site (no inclusion
into or onto article), Industrial use of monomers for
manufacture of thermoplastics, Industrial use of process
regulators for polymerisation processes in production of
resins, rubbers, polymers, Industrial use of substances in
closed systems
Process categories : PROC7: Industrial spraying
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC4: Use of non-
reactive processing aid at industrial site (no inclusion into or onto article)

Amount used
Regional use tonnage : 5.87 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 0.07 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 39.13 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 150
Emission or Release Factor: Air : 0.001 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 0.1 %
Remarks : EUSES A&B tables

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Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Industrial use, Spraying

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <= 8 h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC7: Industrial spraying

Activity : General exposures (open systems), Spraying

Product characteristics
Physical Form (at time of use) : Dustiness: Low

Frequency and duration of use

Frequency of use : <= 4

: , Spraying with no or low compressed air use

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.
(Effectiveness (of a measure): 80 %)
When concentration is:, <25%, No specific measures identified.

2.4 Contributing scenario controlling worker exposure for: PROC7: Industrial spraying

Activity : General exposures (open systems), Spraying

Product characteristics

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Physical Form (at time of use) : Dustiness: Medium

Technical conditions and measures

Minimise exposure by partial enclosure of the operation or equipment and provide extract ventilation
at openings., Apply within a vented cab supplied with filtered air under positive pressure and with a
protection factor of >20. (Effectiveness (of a measure): 95 %)

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.10 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Material transfers, Non-dedicated facility

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems.

2.11 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Material transfers, Dedicated facility

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems.

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC4 EUSES Fresh water 2 mg/L 0.796
Marine water 0.2 mg/L 0.794
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.03 mg/kg 0.032
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

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Scenario Assessment Exposure

Method
PROC7 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC7 ECETOC TRA Long term 0.25 mg/m3 0.17
inhalation
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8b ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation

ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
PROC7: Industrial spraying
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Professional use, Use in spraying formulations.

Main User Groups : SU 22: Professional uses: Public domain (administration,

education, entertainment, services, craftsmen)
Environmental Release Categories : ERC8a, ERC8b, ERC8c, ERC8d, ERC8e, ERC8f, ERC9a,
ERC9b: Wide dispersive indoor use of processing aids in
open systems, Wide dispersive indoor use of reactive
substances in open systems, Wide dispersive indoor use
resulting in inclusion into or onto a matrix, Wide dispersive
outdoor use of processing aids in open systems, Wide
dispersive outdoor use of reactive substances in open
systems, Wide dispersive outdoor use resulting in inclusion
into or onto a matrix, Wide dispersive indoor use of
substances in closed systems, Wide dispersive outdoor use of
substances in closed systems
Process categories : PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC11: Non-industrial spraying

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC8d: Wide

dispersive outdoor use of processing aids in open systems

Activity : Professional use

Amount used
Regional use tonnage : 12 ton(s)/year
(tonnes/year):
Maximum daily site tonnage : 39 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 300
Emission or Release Factor: Air : 100 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 20 %
Remarks : EUSES A&B tables

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Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0.00 %
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Professional use, Spraying

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <= 8 h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Material transfers, Non-dedicated facility

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems.

2.4 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Material transfers, Dedicated facility

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Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems.

2.5 Contributing scenario controlling worker exposure for: PROC11: Non-industrial

spraying

Activity : General exposures (open systems), Spraying

Product characteristics
Physical Form (at time of use) : Dustiness: Low

: , Spraying with no or low compressed air use

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <25%, No specific measures identified.

2.6 Contributing scenario controlling worker exposure for: PROC11: Non-industrial

spraying

Activity : General exposures (open systems), Spraying, Medium

pressure process
Product characteristics
Physical Form (at time of use) : Liquid mixture, Dustiness: Medium

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a
measure): 90 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC8d EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.39
treatment
plant
Soil 0.07 mg/kg 0.084
dry weight

Workers
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Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8b ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC11 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC11 ECETOC TRA Long term 0.4 mg/m³ 0.27
inhalation

ERC8d: Wide dispersive outdoor use of processing aids in open systems

PROC11: Non-industrial spraying
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

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1. Short title of Exposure Scenario: Professional use, Use in non-spraying

formulations., Dustiness: Low

Main User Groups : SU 22: Professional uses: Public domain (administration,

education, entertainment, services, craftsmen)
Environmental Release Categories : ERC8a, ERC8b, ERC8c, ERC8d, ERC8e, ERC8f, ERC9a,
ERC9b, ERC11a: Wide dispersive indoor use of processing
aids in open systems, Wide dispersive indoor use of reactive
substances in open systems, Wide dispersive indoor use
resulting in inclusion into or onto a matrix, Wide dispersive
outdoor use of processing aids in open systems, Wide
dispersive outdoor use of reactive substances in open
systems, Wide dispersive outdoor use resulting in inclusion
into or onto a matrix, Wide dispersive indoor use of
substances in closed systems, Wide dispersive outdoor use of
substances in closed systems, Wide dispersive indoor use of
long-life articles and materials with low release
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
CS100: Production or preparation or articles by tabletting,
compression, extrusion or pelletisation
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal
working operations
PROC18: General greasing/lubrication at high kinetic energy
conditions
PROC19: Manual activities involving hand contact
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC8d: Wide

dispersive outdoor use of processing aids in open systems

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Activity : Professional use

Amount used
Regional use tonnage : 12 ton(s)/year
(tonnes/year):
Maximum daily site tonnage : 39 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 300
Emission or Release Factor: Air : 100 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 20 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0.00 %
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Professional use

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.
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2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Clear transfer lines prior to de-coupling., Closed systems

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

Automated process with (semi) closed systems

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Drain down and flush
system prior to equipment opening or maintenance.

2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Batch process, Open systems

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Batch process, Mixing operations (open

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systems)

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Material transfers, Non-dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Material transfers, Dedicated facility

Technical conditions and measures

No specific measures identified., Use drum pumps., Drain down and flush system prior to equipment
opening or maintenance.

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : Drum and small package filling

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Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

No specific measures identified., Use long handled tools., Avoid splashing.

2.13 Contributing scenario controlling worker exposure for: PROC13: Treatment of

articles by dipping and pouring

Activity : Dipping, immersion and pouring, General exposures (open

systems)

Technical conditions and measures

No specific measures identified., Drain down and flush system prior to equipment opening or
maintenance.

2.14 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.15 Contributing scenario controlling worker exposure for: PROC15: Use as

laboratory reagent

Activity : General exposures, Laboratory activities, Small scale, Manual

Technical conditions and measures

No specific measures identified.

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2.16 Contributing scenario controlling worker exposure for: PROC17: Lubrication at

high energy conditions in metal working operations

Activity : General exposures, Operation and lubrication of high energy

open equipment

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.17 Contributing scenario controlling worker exposure for: PROC18: General

greasing/lubrication at high kinetic energy conditions

Activity : General exposures

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.18 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Technical conditions and measures

No specific measures identified.

2.19 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

When concentration is:, >5%, Provide extraction ventilation at points where emissions occur., Ensure
material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 80 %)
<5%, No specific measures identified.
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3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC8d EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.39
treatment
plant
Soil 0.07 mg/kg 0.084
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC1 ECETOC TRA Long term 0.01 mg/m³ 0.01
inhalation
PROC2 ECETOC TRA Long term 0.01 mg/m3 0.01
inhalation
PROC3 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC4 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC5 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC6 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC8b ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC9 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC10 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC13 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
CS100 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
PROC15 ECETOC TRA Long term 0.1 mg/m³ 0.07
inhalation
PROC17 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
PROC18 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
PROC19 ECETOC TRA Long term 0.5 mg/m³ 0.33

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inhalation
PROC21 ECETOC TRA Long term 0.6 mg/m³ 0.4
inhalation

CS100: Production or preparation or articles by tabletting, compression, extrusion or pelletisation

ERC8d: Wide dispersive outdoor use of processing aids in open systems
PROC1: Use in closed process, no likelihood of exposure
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal working operations
PROC18: General greasing/lubrication at high kinetic energy conditions
PROC19: Manual activities involving hand contact
PROC2: Use in closed, continuous process with occasional controlled exposure
PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC3: Use in closed batch process (synthesis or formulation)
PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities
PROC9: Transfer of substance or preparation into small containers (dedicated filling line,
including weighing)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

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1. Short title of Exposure Scenario: Professional use, Use in non-spraying

formulations., Dustiness: Medium

Main User Groups : SU 22: Professional uses: Public domain (administration,

education, entertainment, services, craftsmen)
Environmental Release Categories : ERC8a, ERC8b, ERC8c, ERC8d, ERC8e, ERC8f, ERC9a,
ERC9b: Wide dispersive indoor use of processing aids in
open systems, Wide dispersive indoor use of reactive
substances in open systems, Wide dispersive indoor use
resulting in inclusion into or onto a matrix, Wide dispersive
outdoor use of processing aids in open systems, Wide
dispersive outdoor use of reactive substances in open
systems, Wide dispersive outdoor use resulting in inclusion
into or onto a matrix, Wide dispersive indoor use of
substances in closed systems, Wide dispersive outdoor use of
substances in closed systems
Process categories : PROC1: Use in closed process, no likelihood of exposure
PROC2: Use in closed, continuous process with occasional
controlled exposure
PROC3: Use in closed batch process (synthesis or
formulation)
PROC4: Use in batch and other process (synthesis) where
opportunity for exposure arises
PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at non-
dedicated facilities
PROC8b: Transfer of substance or preparation (charging/
discharging) from/ to vessels/ large containers at dedicated
facilities
PROC9: Transfer of substance or preparation into small
containers (dedicated filling line, including weighing)
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
CS100: Production or preparation or articles by tabletting,
compression, extrusion or pelletisation
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal
working operations
PROC18: General greasing/lubrication at high kinetic energy
conditions
PROC19: Manual activities involving hand contact
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC8d: Wide

dispersive outdoor use of processing aids in open systems
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Activity : Professional use

Amount used
Regional use tonnage : 12 ton(s)/year
(tonnes/year):
Maximum daily site tonnage : 39 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 300
Emission or Release Factor: Air : 100 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 20 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0.00 %
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Activity : Professional use

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, medium dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
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trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed
process, no likelihood of exposure

Activity : General exposures (closed systems), Continuous process

Technical conditions and measures

No specific measures identified., Handle substance within a closed system., Clear transfer lines prior
to de-coupling.

2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed,
continuous process with occasional controlled exposure

Activity : General exposures (closed systems), Continuous process,

Automated process with (semi) closed systems

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed
batch process (synthesis or formulation)

Activity : General exposures, Use in contained batch processes

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and
other process (synthesis) where opportunity for exposure arises

Activity : General exposures, Open systems, Batch process

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
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When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.8 Contributing scenario controlling worker exposure for: PROC6: Calendering

operations

Activity : General exposures (open systems), Calendering (including

Banburys)

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.9 Contributing scenario controlling worker exposure for: PROC8a: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
non-dedicated facilities

Activity : General exposures, Non-dedicated facility, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

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Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.10 Contributing scenario controlling worker exposure for: PROC8b: Transfer of

substance or preparation (charging/ discharging) from/ to vessels/ large containers at
dedicated facilities

Activity : General exposures, Dedicated facility, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.11 Contributing scenario controlling worker exposure for: PROC9: Transfer of

substance or preparation into small containers (dedicated filling line, including
weighing)

Activity : General exposures, Dedicated facility, Drum and small

package filling, Material transfers

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.12 Contributing scenario controlling worker exposure for: PROC10: Roller

application or brushing

Activity : General exposures (open systems), Rolling, Brushing,

Equipment cleaning and maintenance

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.
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Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.13 Contributing scenario controlling worker exposure for: PROC13: Treatment of

articles by dipping and pouring

Activity : General exposures, Dipping, immersion and pouring

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.14 Contributing scenario controlling worker exposure for: CS100: Production or

preparation or articles by tabletting, compression, extrusion or pelletisation

Activity : General exposures (open systems), Production or preparation

or articles by tabletting, compression, extrusion or pelletisation

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.15 Contributing scenario controlling worker exposure for: PROC15: Use as

laboratory reagent

Activity : General exposures, Laboratory activities, Manual, Small scale

Technical conditions and measures

No specific measures identified.

2.16 Contributing scenario controlling worker exposure for: PROC17: Lubrication at

high energy conditions in metal working operations
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Activity : General exposures, Operation and lubrication of high energy

open equipment

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a full face respirator conforming to EN136 with Type A/P2 filter or better. (Effectiveness (of a
measure): 95 %)

2.17 Contributing scenario controlling worker exposure for: PROC18: General

greasing/lubrication at high kinetic energy conditions

Activity : General exposures

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a full face respirator conforming to EN136 with Type A/P2 filter or better. (Effectiveness (of a
measure): 95 %)

2.18 Contributing scenario controlling worker exposure for: PROC19: Manual activities
involving hand contact

Activity : General exposures, Mixing operations (open systems),

Manual

Conditions and measures related to personal protection, hygiene and health evaluation
Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a
measure): 90 %)

2.19 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
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measure): 75 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC8d EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.39
treatment
plant
Soil 0.07 mg/kg 0.084
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC1 ECETOC TRA Long term 0.01 mg/m³ 0.01
inhalation
Long term mg/kg
dermal bw/day
PROC2 ECETOC TRA Long term 0.2 mg/m3 0.13
inhalation
Long term mg/kg
dermal bw/day
PROC3 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
Long term mg/kg
dermal bw/day
PROC4 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC5 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC6 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC8a ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term mg/kg
dermal bw/day
PROC8b ECETOC TRA Long term 0.25 mg/m³ 0.17

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inhalation
Long term mg/kg
dermal bw/day
PROC9 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC10 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC13 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
CS100 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC15 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term mg/kg
dermal bw/day
PROC17 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term mg/kg
dermal bw/day
PROC18 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term
dermal
PROC19 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term mg/kg
dermal bw/day
PROC21 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term
dermal

CS100: Production or preparation or articles by tabletting, compression, extrusion or pelletisation

ERC8d: Wide dispersive outdoor use of processing aids in open systems
PROC1: Use in closed process, no likelihood of exposure
PROC10: Roller application or brushing
PROC13: Treatment of articles by dipping and pouring
PROC15: Use as laboratory reagent
PROC17: Lubrication at high energy conditions in metal working operations
PROC18: General greasing/lubrication at high kinetic energy conditions
PROC19: Manual activities involving hand contact
PROC2: Use in closed, continuous process with occasional controlled exposure
PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC3: Use in closed batch process (synthesis or formulation)
PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises

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PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)
PROC6: Calendering operations
PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at non-dedicated facilities
PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large
containers at dedicated facilities
PROC9: Transfer of substance or preparation into small containers (dedicated filling line,
including weighing)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

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1. Short title of Exposure Scenario: Industrial use, Building and construction work,
Dustiness: Low

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC12a, ERC12b: Industrial processing of articles with
abrasive techniques (low release), Industrial processing of
articles with abrasive techniques (high release)
Process categories : PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles
PROC24: High (mechanical) energy work-up of substances
bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC12b: Industrial

processing of articles with abrasive techniques (high release)

Amount used
Regional use tonnage : 446 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 0.55 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 1223 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 365
Emission or Release Factor: Air : 1%
Emission or Release Factor: Water : 3.2 %
Emission or Release Factor: Soil : 3.2 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
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water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

No specific measures identified., Use bulk or semi-bulk handling systems., Drain down and flush
system prior to equipment opening or maintenance.

2.4 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)

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2.5 Contributing scenario controlling worker exposure for: PROC24: High (mechanical)
energy work-up of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Roller, spreader, flow

application, Drill floor operations

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC12b EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.04 mg/kg 0.052
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC5 ECETOC TRA Long term 0.5 mg/m³ 0.33
inhalation
Long term mg/kg
dermal bw/day
PROC21 ECETOC TRA Long term 0.2 mg/m3 0.13
inhalation
Long term mg/kg
dermal bw/day
PROC24 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
Long term mg/kg
dermal bw/day

ERC12b: Industrial processing of articles with abrasive techniques (high release)

PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC24: High (mechanical) energy work-up of substances bound in/on materials and/or articles
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)

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4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Industrial use, Building and construction work,
Dustiness: Medium

Main User Groups : SU 3: Industrial uses: Uses of substances as such or in

preparations at industrial sites
Environmental Release Categories : ERC12a, ERC12b: Industrial processing of articles with
abrasive techniques (low release), Industrial processing of
articles with abrasive techniques (high release)
Process categories : PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles
PROC24: High (mechanical) energy work-up of substances
bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC12b: Industrial

processing of articles with abrasive techniques (high release)

Amount used
Regional use tonnage : 446 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 0.55 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 1223 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 365
Emission or Release Factor: Air : 1%
Emission or Release Factor: Water : 3.2 %
Emission or Release Factor: Soil : 3.2 %
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
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water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, medium dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

When concentration is:, >1%, Provide extraction ventilation at points where emissions occur., Ensure
material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 90 %)

Conditions and measures related to personal protection, hygiene and health evaluation
If technical measures not practical:, Wear a respirator conforming to EN140 with Type A/P2 filter or
better. (Effectiveness (of a measure): 90 %)

2.4 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

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When concentration is:, >5%, Provide extraction ventilation at points where emissions occur., Ensure
material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 90 %)
<5%, No specific measures identified.

2.5 Contributing scenario controlling worker exposure for: PROC24: High (mechanical)
energy work-up of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Roller, spreader, flow

application, Drill floor operations

Technical conditions and measures

When concentration is:, >5%, Provide extraction ventilation at points where emissions occur., Ensure
material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 90 %)
<5%, No specific measures identified.

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC12b EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.04 mg/kg 0.052
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC5 ECETOC TRA Long term 0.5 mg/m³ 0.3
inhalation
Long term mg/kg
dermal bw/day
PROC21 ECETOC TRA Long term 0.6 mg/m3 0.4
inhalation
Long term mg/kg
dermal bw/day
PROC24 ECETOC TRA Long term 0.6 mg/m³ 0.4
inhalation
Long term mg/kg
dermal bw/day

ERC12b: Industrial processing of articles with abrasive techniques (high release)

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PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC24: High (mechanical) energy work-up of substances bound in/on materials and/or articles
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Professional use, Building and construction work,
Dustiness: Low

Main User Groups : SU 22: Professional uses: Public domain (administration,

education, entertainment, services, craftsmen)
Environmental Release Categories : ERC10a, ERC10b, ERC11a, ERC11b: Wide dispersive
outdoor use of long-life articles and materials with low release,
Wide dispersive outdoor use of long-life articles and materials
with high or intended release (including abrasive processing),
Wide dispersive indoor use of long-life articles and materials
with low release, Wide dispersive indoor use of long-life
articles and materials with high or intended release (including
abrasive processing)
Process categories : PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles
PROC24: High (mechanical) energy work-up of substances
bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC12b: Industrial

processing of articles with abrasive techniques (high release)

Amount used
Regional use tonnage : 446 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 0.55 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 1223 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 365
Emission or Release Factor: Air : 1%
Emission or Release Factor: Water : 3.2 %
Emission or Release Factor: Soil : 3.2 %
Remarks : EUSES A&B tables

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Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, low dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

When concentration is:, >25%, Provide extraction ventilation at points where emissions occur.,
Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure):
80 %)
<25%, No specific measures identified.

2.4 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

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Technical conditions and measures

When concentration is:, >5%, Provide extraction ventilation at points where emissions occur., Ensure
material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 80 %)
<5%, No specific measures identified.

2.5 Contributing scenario controlling worker exposure for: PROC24: High (mechanical)
energy work-up of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Roller, spreader, flow

application, Drill floor operations

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 75 %)
When concentration is:, <5%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC12b EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.04 mg/kg 0.052
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
PROC5 ECETOC TRA Long term 0.2 mg/m³ 0.13
inhalation
Long term mg/kg
dermal bw/day
PROC21 ECETOC TRA Long term 0.6 mg/m3 0.4
inhalation
Long term mg/kg
dermal bw/day

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PROC24 ECETOC TRA Long term 0.19 mg/m³ 0.13

inhalation
Long term mg/kg
dermal bw/day

ERC12b: Industrial processing of articles with abrasive techniques (high release)

PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC24: High (mechanical) energy work-up of substances bound in/on materials and/or articles
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Professional use, Building and construction work,
Dustiness: Medium

Main User Groups : SU 22: Professional uses: Public domain (administration,

education, entertainment, services, craftsmen)
Environmental Release Categories : ERC10a, ERC10b, ERC11a, ERC11b: Wide dispersive
outdoor use of long-life articles and materials with low release,
Wide dispersive outdoor use of long-life articles and materials
with high or intended release (including abrasive processing),
Wide dispersive indoor use of long-life articles and materials
with low release, Wide dispersive indoor use of long-life
articles and materials with high or intended release (including
abrasive processing)
Process categories : PROC5: Mixing or blending in batch processes for formulation
of preparations and articles (multistage and/ or significant
contact)
PROC21: Low energy manipulation and handling of
substances bound in/on materials and/or articles
PROC24: High (mechanical) energy work-up of substances
bound in/on materials and/or articles

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC12b: Industrial

processing of articles with abrasive techniques (high release)

Amount used
Regional use tonnage : 446 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 0.55 %
region:
Fraction of Regional tonnage used : 100 %
locally:
Maximum daily site tonnage : 1223 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

Number of emission days per year : 365
Emission or Release Factor: Air : 1%
Emission or Release Factor: Water : 3.2 %
Emission or Release Factor: Soil : 3.2 %
Remarks : EUSES A&B tables

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Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to
all above mentioned process categories.

Product characteristics
Concentration of the Substance in : Covers the percentage of the substance in the product up to
Mixture/Article 100 % (unless stated differently).
Physical Form (at time of use) : Solid, medium dustiness
Vapour pressure : < 0.001 Pa
Remarks : Inhalation exposure only via aerosols

Frequency and duration of use

Application duration : <8h
Frequency of use : <= 365 days/year

Other operational conditions affecting workers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

Technical conditions and measures

No specific measures identified.

Organisational measures to prevent /limit releases, dispersion and exposure

Assumes a good basic standard of occupational hygiene is implemented, Ensure operatives are
trained to minimise exposures., Clean equipment and the work area every day., Clear spills
immediately.

2.3 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending
in batch processes for formulation of preparations and articles (multistage and/ or
significant contact)

Activity : General exposures, Mixing operations (open systems), Batch

process

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

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2.4 Contributing scenario controlling worker exposure for: PROC21: Low energy
manipulation and handling of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Manual

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >25%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

2.5 Contributing scenario controlling worker exposure for: PROC24: High (mechanical)
energy work-up of substances bound in/on materials and/or articles

Activity : General exposures (open systems), Roller, spreader, flow

application, Drill floor operations

Technical conditions and measures

Provide extraction ventilation at points where emissions occur., Ensure material transfers are under
containment or extract ventilation. (Effectiveness (of a measure): 80 %)
When concentration is:, <1%, No specific measures identified.

Conditions and measures related to personal protection, hygiene and health evaluation
When concentration is:, >5%, Wear a disposable mask FFP1 (APF=4) or better (Effectiveness (of a
measure): 75 %)

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC12b EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.04 mg/kg 0.052
dry weight

Workers

Contributing Exposure Specific conditions Value Level of RCR

Assessment
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Scenario Method Exposure

PROC5 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC21 ECETOC TRA Long term 0.25 mg/m3 0.17
inhalation
Long term mg/kg
dermal bw/day
PROC24 ECETOC TRA Long term 0.25 mg/m³ 0.17
inhalation
Long term mg/kg
dermal bw/day

ERC12b: Industrial processing of articles with abrasive techniques (high release)

PROC21: Low energy manipulation and handling of substances bound in/on materials and/or
articles
PROC24: High (mechanical) energy work-up of substances bound in/on materials and/or articles
PROC5: Mixing or blending in batch processes for formulation of preparations and articles
(multistage and/ or significant contact)

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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1. Short title of Exposure Scenario: Consumer use

Main User Groups : SU 21: Consumer uses: Private households (= general public
= consumers)
Environmental Release Categories : ERC8a, ERC8b, ERC8c, ERC8d, ERC8e, ERC8f, ERC9a,
ERC9b, ERC11a: Wide dispersive indoor use of processing
aids in open systems, Wide dispersive indoor use of reactive
substances in open systems, Wide dispersive indoor use
resulting in inclusion into or onto a matrix, Wide dispersive
outdoor use of processing aids in open systems, Wide
dispersive outdoor use of reactive substances in open
systems, Wide dispersive outdoor use resulting in inclusion
into or onto a matrix, Wide dispersive indoor use of
substances in closed systems, Wide dispersive outdoor use of
substances in closed systems, Wide dispersive indoor use of
long-life articles and materials with low release
Chemical product category : PC1: Adhesives, sealants
PC9a: Coatings and paints, thinners, paint removers
PC9b: Fillers, putties, plasters, modelling clay
PC12: Fertilizers
PC20: Processing aids such as pH-regulators, flocculants,
precipitants, neutralization agents
PC29: Pharmaceuticals
PC35: Washing and cleaning products
PC36: Water softeners
PC39: Cosmetics, personal care products

Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic

acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC8a: Wide

dispersive indoor use of processing aids in open systems

Activity : Consumer use

Amount used
Regional use tonnage : 810 ton(s)/year
(tonnes/year):
Fraction of EU tonnage used in : 10 %
region:
Fraction of Regional tonnage used : 0.176 %
locally:
Maximum daily site tonnage : 39.13 kg/day
(kg/day):

Environment factors not influenced by risk management

Flow rate : 18,000 m3/day
Dilution Factor (River) : 10
Dilution Factor (Coastal Areas) : 100

Other given operational conditions affecting environmental exposure

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Number of emission days per year : 365

Emission or Release Factor: Air : 10 %
Emission or Release Factor: Water : 100 %
Emission or Release Factor: Soil : 1%
Remarks : EUSES A&B tables

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal sewage treatment plant
Flow rate of sewage treatment : 2,000 m3/day
plant effluent
Percentage removed from waste : 0%
water

2.2 Contributing scenario controlling consumer exposure for: PC9a, PC9b, PC12,
PC36, PC39, PC29: Coatings and paints, thinners, paint removers, Fillers, putties,
plasters, modelling clay, Fertilizers, Water softeners, Cosmetics, personal care
products, Pharmaceuticals

Product characteristics
Concentration of the Substance in : Covers percentage substance in the product up to 40%.
Mixture/Article
Physical Form (at time of use) : Liquid (aqueous solution) or solid salts (assumed to be in
granular/flake form rather than powdered), paste
Remarks : For non-spraying processes (no aerosol generation), an
inhalative exposure is considered to be not relevant.

Amount used
Amount used : 0.2 kg

Frequency and duration of use

Frequency of use : 365 event(s)/year

2.3 Contributing scenario controlling consumer exposure for: PC35: Washing and
cleaning products

Activity : All purpose cleaners, Oven cleaners, Glass cleaners

Product characteristics
Physical Form (at time of use) : Spray

Amount used
: 19.5 gram

Frequency and duration of use

Frequency of use : 52 event(s)/year
Remarks : Spraying

Other given operational conditions affecting consumers exposure

Outdoor / Indoor : Indoor
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Outdoor / Indoor : Outdoor

Conditions and measures related to protection of consumer (e.g. behavioural advice,

personal protection and hygiene)
Consumer Measures : Do not touch eyes when using this product., Spraying away
from exposed person

2.4 Contributing scenario controlling consumer exposure for: PC35: Washing and
cleaning products

Activity : Residues on clothing

Frequency and duration of use

Frequency of use : 365 days/year

Other given operational conditions affecting consumers exposure

Outdoor / Indoor : Indoor
Outdoor / Indoor : Outdoor

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC4 EUSES Fresh water 2 mg/L 0.8
Marine water 0.2 mg/L 0.8
Sewage 19.6 mg/L 0.391
treatment
plant
Soil 0.027 mg/kg 0.032
dry weight

Consumers

Contributing Exposure Specific conditions Value Level of RCR

Scenario Assessment Exposure
Method
All PCs Use in non-spraying
formulations., Pastes, solid
Consexpo Oven cleaners, Spray Long term 0.027 mg/m³ 0.01
inhalation
Residues on clothing Long-term 0.14 mg/kg 0.01
oral bw/day

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All PCs: Applicable to all above mentioned product categories.

ERC4: Use of non-reactive processing aid at industrial site (no inclusion into or onto article)
No exposure assessment has been performed
The substance has a very low vapor pressure and is not dusty
Dermal exposure is considered to be not relevant since the substance has a negligible dermal uptake

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm
Guidance is based on assumed operating conditions which may not be applicable to all sites; thus,
scaling may be necessary to define appropriate site-specific risk management measures.

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1. Short title of Exposure Scenario: Consumer use, Used for personal care products

Main User Groups : SU 21: Consumer uses: Private households (= general public
= consumers)
Environmental Release Categories : ERC10a, ERC11a: Wide dispersive outdoor use of long-life
articles and materials with low release, Wide dispersive indoor
use of long-life articles and materials with low release
Further information : ,The exposure scenario covers:, Ethylenediaminetetraacetic
acid, disodium salt

2.1 Contributing scenario controlling environmental exposure for: ERC10a, ERC11a:

Widespread use of articles with low release (outdoor), Wide dispersive indoor use of
long-life articles and materials with low release

Activity : Consumer use

Amount used
Daily amount for wide dispersive : 0.000055 tonnes/day
uses

Other given operational conditions affecting environmental exposure

Emission or Release Factor: Air : 0.05 %

Emission or Release Factor: Water : 3.2 %
Emission or Release Factor: Soil : 3.2 %

Conditions and measures related to municipal sewage treatment plant

Type of Sewage Treatment Plant : Municipal Sewage Treatment Plant
Percentage removed from waste : 70 %
water

3. Exposure estimation and reference to its source

Environment

Contributing Exposure Specific Compartment Value Level of RCR

Scenario Assessment conditions Exposure
Method
ERC10a EUSES Fresh water 0.019 mg/L < 0.01
ERC11a Marine water 0.00188 mg/L < 0.01
Sewage 0.000264 < 0.01
treatment mg/L
plant
Soil 0.00616 < 0.01
mg/kg dry
weight
Secondary Oral 0.00159 < 0.01
Poisoning exposure mg/kg bw/day

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ERC10a: Wide dispersive outdoor use of long-life articles and materials with low release
ERC11a: Wide dispersive indoor use of long-life articles and materials with low release

4. Guidance to Downstream User to evaluate whether he works inside the

boundaries set by the Exposure Scenario

For further information, please also consult our Internet site: Downstream Users
http://guidance.echa.europa.eu/downstream_users_en.htm

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