This document provides information for parents and carers on using the medicine enoximone to treat pulmonary hypertension in children. It details how much to give, when to give it, possible side effects, and storage instructions.
This document provides information for parents and carers on using the medicine enoximone to treat pulmonary hypertension in children. It details how much to give, when to give it, possible side effects, and storage instructions.
This document provides information for parents and carers on using the medicine enoximone to treat pulmonary hypertension in children. It details how much to give, when to give it, possible side effects, and storage instructions.
This document provides information for parents and carers on using the medicine enoximone to treat pulmonary hypertension in children. It details how much to give, when to give it, possible side effects, and storage instructions.
This leaflet is about the use of enoximone for pulmonary hypertension.
This leaflet is for parents and carers about how to use this medicine. They should drink it all straight away. You medicine in children. Our information sometimes differs from should not add the medicine to other drinks such as that provided by the manufacturers, because their information water or juice. is usually aimed at adults. Please read this leaflet carefully. • Keep the other prepared syringes at room temperature Keep it somewhere safe so that you can read it again. and use them for the doses over the next 24 hours. Throw away syringes 24 hours after they were prepared Name of drug if they have not been used. Enoximone • Do not store the ampoules or syringes in the fridge as Brand name: Perfan this can cause the liquid to crystallise.
Why is it important for my child to take this medicine? When should the medicine start working? Pulmonary hypertension means high blood pressure in Your child will usually start the medicine while in hospital. It the lungs, which often occurs after heart surgery. Taking will start to work within a few days although you may not enoximone will reduce the blood pressure in the lungs, which notice any difference in your child. The doctors will check that helps the lungs to work properly. it is helping your child.
What is enoximone available as? What if my child is sick (vomits)?
• Ampoules containing 100 mg in 20 mL (5 mg in 1 mL); • If your child is sick less than 30 minutes after having a these may contain small amounts of propylene glycol dose of enoximone, give them the same dose again. and alcohol. If you have any concerns or questions, • If your child is sick more than 30 minutes after having speak with your child’s doctor or pharmacist. a dose of enoximone, you do not need to give them another dose. Wait until the next normal dose. When should I give enoximone? If your child is sick again, seek advice from your doctor, Enoximone is usually given three times each day. This pharmacist or hospital. They will decide what to do based on should be first thing in the morning, early afternoon and at your child’s condition and the specific medicine involved. bedtime. Ideally, these times are at least 6 hours apart, for example 8am, 2pm and 8pm. What if I forget to give it? Give the medicine at about the same times each day so that • If you miss a dose, wait until the next normal dose. Do this becomes part of your child’s daily routine, which will help not give the missed dose. you to remember. Never give a double dose of enoximone. How much should I give? What if I give too much? Your doctor will work out the amount of enoximone (the dose) that is right for your child. The dose will be shown on the It can be dangerous to give too much enoximone. medicine label. If you are concerned that you may have given too much, It is important that you follow your doctor’s contact your doctor or local NHS services (details at end of instructions about how much to give. leaflet) or take your child to hospital. Have the medicine or packaging with you if you telephone for advice. How should I give it? Are there any possible side-eff ects? • This medicine is given by mouth to children with pulmonary hypertension. We use medicines to make our children better, but sometimes they have other effects that we don’t want • Open the ampoule and draw up the right volume into a (side-effects). plastic syringe. You can prepare one day’s doses (three syringes) from one ampoule. Side-eff ects you must do something about • Put the ampoule and any remaining contents into the Your child may get an irregular or fast heart beat. (Your sharps container provided. child may say that their heart is racing or feels fluttery.) • Give your child one dose (one syringe) by squirting the Contact your doctor straight away if this happens. contents gently into the side of their mouth. They should If your child has any unexplained bruising or bleeding, then swallow the liquid. or cuts don’t stop bleeding quickly, contact your doctor • You can empty the syringe contents into a very small straight away as there may be a problem with your glass of milk just before your child is due to take the child’s blood. Other side-effects you need to know about • Only give this medicine to your child. Never give it to • Your child may have stomach ache or cramps and may anyone else, even if their condition appears to be the feel sick or be sick (vomit). This usually wears off after a same, as this could do harm. few days. It may help to give each dose with some food. If you think someone else may have taken the medicine If this is still a problem after taking the medicine for a by accident, contact your doctor straight away. week, contact your doctor. • Make sure that you always have enough medicine. • Your child may not feel very hungry. Encourage them to Order a new prescription at least 2 weeks before you eat smaller meals more often than usual. If this is still a will run out. problem after a week, contact your doctor. • Make sure that the medicine you have at home has There may sometimes be other side-effects that are not listed not reached the ‘best before’ or ‘use by’ date on the above. If you notice anything unusual and are concerned, packaging. Give old medicines to your pharmacist to contact your doctor or pharmacist. dispose of. You can report any suspected side-effects to a UK safety scheme at www.mhra.gov.uk/yellowcard Where I should keep this medicine? More information on side-effects can be found in the following • Keep the medicine in a cupboard, away from heat and leaflet www.medicinesforchildren.org.uk/side-effects- direct sunlight. childrens-medicines • It should not be kept in the fridge as the solution may crystallise. Can other medicines be given at the same time as • Make sure that children cannot see or reach the enoximone? medicine. • You can give your child medicines that contain • Keep the medicine in the container it came in. paracetamol or ibuprofen, unless your doctor has told you not to. Who to contact for more information • Enoximone should not be taken with some medicines Your child’s doctor, pharmacist or nurse will be able to give that you get on prescription. Tell your doctor and you more information about enoximone and about other pharmacist about any other medicines your child is medicines used to treat pulmonary hypertension. taking before giving enoximone. You can also get useful information from: • Check with your doctor or pharmacist before giving any England: NHS 111 other medicines to your child. This includes herbal or Tel 111 - www.nhs.uk complementary medicines. Scotland: NHS 24 Is there anything else I need to know about Tel 111 - www.nhs24.scot enoximone? • Enoximone is often given by intravenous injection. The Wales: NHS 111 Wales same liquid can be given by mouth to children with Tel 111 - www.111.wales.nhs.uk pulmonary hypertension. Northern Ireland: NI Direct General advice about medicines www.nidirect.gov.uk • Try to give medicines at about the same times each day, to help you remember. The Pulmonary Hypertension Association • If you are not sure a medicine is working, contact your Tel 01709 761450 www.phassociation.uk.com doctor but continue to give the medicine as usual in the meantime. Do not give extra doses as you may do harm.
Knowledge, Attitude and Practice Regarding Adverse Drug Reaction Monitoring & Reporting Amongst Physicians in A Tertiary Care Teaching Hospital, Ahmedabad Indian Journal of Applied Research
