C146-E367C

Gas Chromatograph Mass Spectrometer

GCMS-QP2020 NX
Smart Solutions Expanding the Possibilities of Laboratories to their Fullest Potential

GC/MS is now a standard analytical technique used in a variety of fields. With each new
development, requests for more cost-effective systems and improvements in the work-life
balance of users grow. Dedicated to improving efficiency, the GCMS-QP2020 NX can assist
any laboratory, regardless of its analysis focus, achieve its full potential.
 Smart Performance
Provides Higher Sensitivity and Reduces Operational Costs

A large-capacity differential exhaust turbomolecular pump and a high-performance flow controller ensure that the
utmost in sensitivity is obtained under all conditions used for GC. This sensitivity combined with high-speed analysis
capabilities helps maximize laboratory efficiency by reducing analysis times. In addition, the system can be safely
operated using carrier gases other than helium, such as hydrogen or nitrogen, thereby reducing operating costs.

Technology Achieves High Sensitivity

Ion Source Featuring High Sensitivity and Long-Term Stability

The filament and the ion source box have been separated, which reduces
the impact of the filament potential on the interior of the ion source.
In addition, a shield is provided to block radiant heat generated by the
filament, achieving a uniform temperature inside the ion source box. Thus,
active spots inside the ion source are not prone to occur, enabling
high-sensitivity analysis with long-term stability. (Patent: US7939810)

Shield Temperature

Low High

: Filament
: Electric field
: Heat rays

Shield

(×1,000) (×1,000)
1.00 274.00 3.0 354.00
246.00 306.00
2.5
0.75
2.0

0.50 1.5

1.0
0.25
0.5

14.25 14.50 14.75 15.00 15.25 15.50 12.00 12.25 12.50 12.75 13.00 13.25

Phenthoate (5 ng/mL) Dithiopyr (5 ng/mL)

Large-Capacity Differential Exhaust System

Through adoption of a new type of turbomolecular pump with increased exhaust efficiency, the
system's performance is greatly improved when using hydrogen or nitrogen, in addition to
helium, as the carrier gas. Moreover, a differential exhaust method is used to create a vacuum
separately for the ion source and the quadrupole. As a result, an optimal MS state can be
realized regardless of the conditions imposed by the carrier gas used.

High-Speed Scan Control Technology

Advanced Scanning Speed Protocol (ASSP ™)
The rod bias voltage is automatically optimized during
Diazinon
high-speed data acquisition, which minimizes
sensitivity deterioration during high-speed scans of Propyzamide
10,000 u/sec or faster. The sensitivity obtained is at
least five times better than with conventional systems.
This is effective for scan data sensitivity improvements
Black: 1,111 u/sec
and favorable mass spectrum acquisition, particularly
Red : 5,000 u/sec
in high-speed analysis with Fast-GC/MS, simultaneous Blue : 10,000 u/sec
Newly Patented Technology (ASSP)
Scan/SIM, FASST analysis, and applications using GC ×
GC-MS. (Patent: US6610979)

4
 New Flow Controller Achieves Exceptional Reproducibility Split filter

A new flow controller (AFC) with a CPU uses various control methods to control carrier
gas flow to a constant flow speed, flowrate, or pressure. It can also accurately trace the
analytical conditions already being used.
The split line filter can be replaced without any tools. Internal contamination can be
confirmed visually, ensuring filters are replaced at the proper time.

Valve

Flow Controller
(AFC-2030)

One Touch Inlet Maintenance

The injection port can be opened or closed without tools
by simply sliding the ClickTek™ lever. Replace the insert,
slide the lever and feel the click for a leak-free install every
time.

ClickTek Nut

Area value Retention time

%RSD %RSD
Acenaphthylene 0.969 0.005
Fluorene 0.918 0.007
Advanced GC Oven Phenanthrene 1.075 0.006
Anthracene 1.141 0.007
The improved temperature control Pyrene 1.263 0.004
Benz[a]anthracene 1.405 0.005
function enables more precise Chrysene 1.283 0.005
Benzo[b]fluoranthene 1.940 0.003
temperature control of the GC oven, Benzo[k]fluoranthene 1.268 0.003
which improves the precision of Benzo[a]pyrene 0.781 0.005
Indeno[1,2,3-cd]pyrene0.744 0.004
retention time reproducibility. Dibenz[a,h]anthracene 0.836 0.004
In addition, three oven cooling rate 17.45 17.50 17.55 Benzo[ghi]perylene 0.767 0.004

levels can be specified to minimize Mass Chromatogram of Benzo[a]pyrene Repeatability with Polycyclic
damage to column liquid phases and (Overlaid plotting of measurements repeated eight times) Aromatic Hydrocarbons (PAHs)

maximize the service life.

5
 Reduced Operating Costs Using Alternative Carrier Gases
Hydrogen and nitrogen are less expensive than helium and are readily available, so they are attracting attention as
alternative carrier gases. The high-performance Advanced Flow Controller (AFC) provides accurate control even with
hydrogen and nitrogen. In addition, the new large-capacity differential exhaust system enhances the vacuum
performance when hydrogen or nitrogen is used as the carrier gas, so the optimal MS state is achieved under all
carrier gas conditions.

Application Example Using Hydrogen as the Carrier Gas

Hydrogen and nitrogen provide less sensitivity than helium.
However, chromatogram patterns equivalent to when helium is
He H2
used can be obtained by using a short column with a narrow
internal diameter. EZGC ® Method Translator* 1, a method
conversion program provided by Restek, can convert the analysis
conditions when helium is used to the optimal analysis conditions
for the alternative carrier gas.

(×10,000) (×100)
191.00 8.0
272.00
2.00
193.00 274.00
1.75 7.0

1.50 6.0
1.25
5.0
1.00

0.75 4.0

0.50
3.0
0.25
6.00 6.25 6.50 6.75 14.50 14.75 15.00 15.25
Chloroneb Endosulfate

Mass Chromatograms of Pesticides (5 ng/mL, SIM)

The retention indices are essentially unchanged even when the

conventionally used analysis conditions are converted for using
hydrogen as the carrier gas. Mass spectral libraries containing
retention indices and databases provided by Shimadzu should be
used.
EZGC Method Translator

*1 EZGC is a trademark of Restek Corporation.

For details, refer to the Restek Corporation website.
http://www.restek.com/ezgc-mtfc

Hydrogen sensor

Hydrogen Sensor Assures Safety

A hydrogen sensor (optional) can be installed inside the GC. By
discovering potential leaks in advance, accidents can be prevented.
Furthermore, the main unit is equipped with an automatic carrier
gas leak checking function, which strongly supports the use of
hydrogen as a carrier gas.

Hydrogen Sensor Monitors Inside of GC Oven

6
Application Example Using Nitrogen as the Carrier Gas
The use of helium as the carrier gas is a major contributor to instrument
operating costs.
Nitrogen is approximately 10 times less expensive than helium, so
significant reductions in operating costs can be expected by utilizing
He N2
nitrogen as the carrier gas.

(×1,000)
%RSD = 2.63

5.0 He

2.5
H2
0.0
N2
(×1,000)

%RSD = 3.74
1 pg 10 pg 100 pg 1 ng 10 ng
1.5

Indication of Measurement Range for Each Carrier Gas

1.0 (On-Column Amount)
These measurement ranges are at best only guidelines, and may be
unsuitable depending on the target compound sensitivities and the
0.5 compound characteristics.

SIM Mass Chromatogram for DINP

(0.5 μg/mL, overlay at 7 replicates)
Top: Helium Carrier Gas (99.99%, with gas purification filter)
Bottom: Nitrogen Carrier Gas (99.99%, with gas purification filter)

Equivalent chromatogram patterns and mass spectra were obtained even though the analysis conditions used with
helium as the carrier gas were converted for using nitrogen as the carrier gas. This can be applied for purposes of
qualitative analysis including the analysis of evolved gases from polymeric materials.
(×10,000,000)
3.0
TIC
%
2.0 100 213

1.0 50
119 228
65 77 91 135 165
0
5.0 10.0 15.0 20.0 50 100 150 200 250

(×10,000,000)
5.0
TIC
%
100 213
2.5

50
119 228
65 77 91 135 165
0.0 0
5.0 10.0 15.0 20.0 50 100 150 200 250
Sample Analysis of the Instantaneous Thermal Decomposition of an Electronic Board Utilizing Py-GC/MS
(mass spectrum for bisphenol A)
Top: Helium Carrier Gas (99.99%, with gas purification filter)
Bottom: Nitrogen Carrier Gas (99.99%, with gas purification filter)

7
 Smart Performance
Easily Obtains All the Information Required for Qualitative Analysis

With GC/MS, which has significant qualitative capabilities, a wealth of fragment information is obtained, so it is used
as a means of identifying unknown compounds. A mass spectral library is generally used as a means of compound
identification. However, experience with compound identification is required if the compound is not registered in the
mass spectral library, or there are a number of compounds with similar structures. With the GCMS-QP2020 NX, in
addition to the mass spectrum, three kinds of value-added compound information are used in combination to support
high-accuracy qualitative analysis.

Retention Index Databases containing retention indices

MassWorks software,
Quick-CI, which can perform which is capable of
collection consecutively in Molecular Weight Accurate Mass* calculating the accurate
EI and CI modes mass and estimating
composition
* Accurate mass refers to the accurate mass calculated mathematically by MassWorks.

Databases Containing High Smart Metabolites

Database
Value-Added Retention Indices Simultaneous Off-Flavor
Analysis Database Database
Databases are available with retention indices specific to a
variety of application fields, including foods, chemistry, Retention Indices
fragrances, forensics, and metabolite component analysis. In Forensic Toxicology
Pesticide Library
addition to mass spectra, searches are performed in Database
combination with retention indices, which are very highly Polymer Additives
compound specific, so isomers and compounds with similar Library

structures are accurately identified.

Other Mass Spectra Libraries
• NIST Mass Spectral Library
Registered with approx. 350,643 spectra.
• WILEY Mass Spectral Library
Registered with approx. 775,500 spectra.
• GC/MS MPW DRUG Library
Up to 10 library files can be configured. In addition to the public NIST and
Drugs, toxicants, pesticides,
Wiley libraries, a variety of library files can be configured. In addition, there environmental pollutants
is a function to easily create private libraries. (approx. 10,430 compounds)

Narrowed by retention index

8
 Smart EI /CI Ion Source Easily Switches Between EI and CI Methods
The Smart EI/CI ion source has been developed in order to acquire CI data without switching the ion source, and
without losing the sensitivity of EI, which is most commonly used.
Even when it is difficult to perform identification with the EI mode using the mass spectral library, molecular weight
information can be obtained from CI data, thus helping in the estimation of unknown compounds.

100 EI 441 Exchange of 100 CI 441

57
ion source
75 unnecessary 75

50 50 647
25 25
91 191 308 385 106 329 385 483 591
0 0
250 500 250 500
Confirmation of Mass Spectra Smart EI/CI Ion Source Confirmation of Molecular Weight Information

MW:646

m/z 441
EI Data
It can be estimated that the peak
CI Data
shown with an asterisk in the graph
5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 min on the left is Tris
Analysis of Extracts from a Food Container (Extracted using 20% EtOH solution)
(2,4-di-t-butylphenyl) phosphite,
which is used as an antioxidant,
based on the EI mass spectrum and
the molecular weight information
provided by CI spectra.

Estimating Composition Using Accurate Mass

The MassWorks software calculates the theoretical
accurate mass from the quadrupole MS mass profile. It m/z 371 Mass Profile (CI)
then outputs candidate compositional formulas based
on isotopic ratios and the theoretical accurate mass. This
software is useful for estimating the composition of
compounds that are not registered in a mass spectral
library.
The GCMSsolution ™ software can simultaneously output
GC/MS data and mass profile data. The majority of
compounds detected with the GC/MS data can be
identified from a mass spectral library. MassWorks is
then used to estimate the composition of any
compounds that are not identified, further increasing
the quality of the qualitative analysis.
(×10,000,000)

7.5

5.0

It is predicted to be diethylhexyl adipate (C22H42O4) based on the

2.5 candidate compositional formula and the mass spectral pattern.
EI Data
0.0 CI Data
8.0 9.0 10.0 11.0 12.0 13.0
Sample Analysis of Additives in a Polymer

9
 Smart Productivity
Efficient Operation of the System with Time Management Function

The GCMS is now a standard system for analysts, and a single system can be used for a wide variety of applications.
The active time management feature appropriately manages times when the system requires maintenance, or when
system changes are being made, or the waiting time for a user when multiple users are waiting to use the system. This
ensures more efficient use of the system and greater uptime.

Active-Time Management™ That Accurately Determines Operation Time

Time Management during Instrument Startup / Shutdown

The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time
depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes
when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion
source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks
upon system startup and auto tuning, are now performed automatically.

Auto Startup and Shutdown

Auto Tuning Check Result

Time Management during Sample Injection Port Maintenance

The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the
remaining time (cooling-down time) when the septum or the insert can be replaced in real time. Maintenance time
can be minimized by understanding the accurate remaining time.
Furthermore, by using a ClickTek nut on the top of the sample injection port, the port can be opened or closed
without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever
before.

Easy sTop Function ClickTek Nut

10
Time Management for Continuous Analysis
By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish
can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required
during continuous analysis or while switching between different users. In addition, because this function makes it easier to
schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the
previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.

Time display for continuous analysis can be used only in liquid injection using AOC-20i.

Twin Line MS System Eliminates the Need to Swap Columns

The GCMS-QP2020 NX is capable of accepting installation of two narrow-bore capillary columns into the MS
simultaneously. This allows you to switch applications without physically modifying the column installation. Simply
decide which column is best for your analysis and choose the associated injection port.

Low polarity column

Middle polarity column

Analysis of Flavor and Fragrance Components Using

Complementary Column Phases

11
 Smart Operation
Dramatic Improvement in the Efficiency of Multicomponent Simultaneous Analysis

The efficiency of multi-component simultaneous analysis is dramatically improved thanks to Smart SIM ™, which
simplifies and automates the method creation, and LabSolutions Insight ™ software, which greatly reduces the time
needed for analyzing data.
In addition, databases specialized for specific fields are provided, so regardless of the field in which quantitative
analysis is to be performed, highly reliable data can be obtained as the result of the optimized analytical
conditions.

More Convenient Multicomponent Analysis Achieved by Smart SIM

The Smart SIM automatic method creation function automatically configures the SIM program to suit the
retention times. Even in cases where there are a number of compounds and they are apportioned to multiple
methods, the methods can be integrated while maintaining the sensitivity as is. This significantly reduces the
number of analysis cycles and the measurement time, improving productivity.

The optimal MS table is

automatically created

Smart SIM

All compound information contained in methods for currently used Shimadzu GC/MS systems can be stored in the
database simply by selecting the files.

High-sensitivity, high-accuracy analysis is enabled in comparison to the group measurement method. In a batch
analysis of 434 components, favorable repeatability and calibration curves were obtained, even down to the
trace-quantity region, improving quantitative performance.
Conventional Method
Smart SIM Y = 8320.518X − 2899.459 (Group Measurement) Y = 7547.102X − 26544.7
R^2 = 0.999566 R^2 = 0.9921897
1 (#1) R = 0.999783 1 (#1) R = 0.9960872
Zoxamide Zoxamide
1 (#2) Average RF: 8604.262 1 (#2) Average RF: 6020.259
2 ppb RF SD: 1,424.947 2 ppb RF SD: 1,293.612
1 (#3) 1 (#3)
%RSD = 2.4% RF %RSD: 16.56094 %RSD = 24.9% RF %RSD: 21.48766
1 (#4) 1 (#4)
(n = 6) Area (n = 6) Area
1 (#5) 1 (#5)
1 (#6) 800000 1 (#6) 700000
700000 600000
600000
500000
500000
400000
400000
300000 300000
200000 200000
100000 100000
0 0
17.3 17.4 17.5 17.6 17.7 17.8 0 10 20 30 40 50 60 70 80 90 Conc. 17.2 17.3 17.4 17.5 17.6 17.7 0 10 20 30 40 50 60 70 80 90 Conc.

12
 Functions Using Retention Indices
Automatic Adjustment of Compound Retention Time (AART) C17 C18 C19

The AART (Automatic Adjustment of Retention Original registered

method information
Time) function can estimate the retention times of
target components from retention indices and the
1700 1735 1800 R.I.
retention times of an alkane standard mix*. C17 C18 C19
* Requires alkane mix which is sold separately. Identification
Customer’s Window
Instrument

1700 1735 1800 R.I.

20 21 22 Retention time
21.1 min 21.5 min Analyte
(Calculated RT) (Originally registered RT)
Automatic Adjustment

Databases Specific to All Kinds of Industries

Databases are available for a variety of GC/MS Forensic Toxicological Database
industries, and contain analysis conditions
optimized for multicomponent batch analysis. Analysis of serum 318.00
272.00
Analysis can start immediately just by 233.00

automatically correcting the retention times

utilizing the AART function. 23.0 23.5
Chlorpromazine

Smart Metabolites 5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 25.0 27.5 30.0 32.5 35.0

Database It is pre-registered with more than 1400 mass spectra including free-, TMS- and TFA-body
types for compounds that are required in forensic toxicological analysis of drugs of abuse,
drugs for psychiatric and neurological disease, and other medicines and pesticides.

Simultaneous Off-Flavor Compound Composer Database Software

Analysis Database Database
for Simultaneous Analysis (Environmental Analysis)
Analysis of river water 213

Forensic Toxicology Quick-DB

Database Pesticide Database
26.00 26.50
Bisphenol A

5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 25.0 27.5 30.0 32.5 35.0

Simultaneous GC/MS analysis supporting identification and quantification of 942

environmental pollutants can be performed.
The retention times and calibration curve information of environmentally hazardous
chemical substances are registered, so approximate concentrations can be obtained, even
when it is difficult to obtain standards.

Quantitation Analysis Without Using Standard Samples

Quick-DB ™ GC/MS Residual Pesticides Database is preregistered with calibration curves created utilizing pesticide
surrogates, enabling quantitative analysis without having to create methods using standards. A total of 474 components
(for scan or SIM mode) are contained in the database, enabling the comprehensive quantitative analysis of pesticides.
(Compound Composer Database Software and GC/MS Forensic Toxicological Database also contain this function.)

Calibration curves of the relative ratio of

Intensity Internal Intensity internal standard substances are
Pesticide Standard Internal preregistered. A semi-quantitative value is
Substance
Pesticide Standard acquired by adding an internal standard to a
Substance
sample. If accurate quantitative values are
required, be sure to quantify them using a
conventional method.

Ratio on Database Ratio on Actual Instrument

(Tolclofos-methyl: 10 ng/mL)

13
 Multianalyte Data Analysis with More Efficiency Using LabSolutions Insight
LabSolutions Insight quantitative analysis support software includes functionality for enhancing the throughput of
multianalyte data analysis, making it especially helpful for routine analysis. Quantitative results for a series of data sets
can be displayed at the same time for data analysis. Chromatograms for each set of sample data can be displayed
side-by-side for each compound, making it easy to confirm peak detection and quantitative results. Color-coded flagging
functionality makes it easy to quickly see peaks from any of multiple analytes that exceed criteria values. That drastically
decreases the number of peaks that need to be checked and improves the efficiency of quantitative analysis processes.

More Efficient Multianalyte Data Analysis

Users can select the optimal method for displaying data based on their workflow. For example, data analysis windows can
be displayed for each target compound or each set of measurement data, or quantitation or area values can be displayed as
a list. If necessary, quantitative analysis can be repeated with peaks directly corrected, which provides intuitive operability.

Visualization of Quantitative and Accuracy Control Results

Quantitative and accuracy control results can be presented more clearly by using the flagging function to color-code result
values that exceed specified criteria values or by only displaying flagged results. Five levels of criteria values can be indicated
for quantitative results, making it easy to confirm the corresponding criteria value range for the detected compounds.
Flagging immediately reflects results from any corrections made to manual peak integration or calibration curves.

Cautionary Warning

0.000001 mg/L 0.00001 mg/L

Network Support Laboratory

GC/MS analysis LC/MS analysis

Data acquired from multiple systems
can be reviewed or confirmed using
client computers connected via a
LAN or other network. If multiple
systems are used, data obtained
from each system can be reviewed Operator Operator

from any client computer. Even in

the case of multiple analysts using
the same system, the ability to Office
separate analytical work from
Data review
measurement work improves
efficiency.
File Server

Client PC

Analysis administrator
Client PC Client PC Client PC
Data confirmation Operator Operator Operator

File management on a file server is recommended for systems with more than five users.

14
Enhanced Support System for Data Management
LabSolutions ™ DB/CS Realizes Complete Data Integrity*

LabSolutions DB/CS is the integration software for analytical instruments that complies with regulations regarding electron-
ic records and signatures, such as "FDA 21 CFR Part 11" and "ER/ES guidelines".
Data management with LabSolutions prevents overwriting or deleting analysis data. It also offers a complete suite of
advanced security features to provide an optimal solution for data integrity.

Network System: LabSolutions CS

Data acquired from multiple systems can be reviewed or confirmed using client computers connected via a LAN or other
network. If multiple systems are used, data obtained from each system can be reviewed from any client
computer. Even in the case of multiple analysts using the same system, the ability to separate analytical work from measure-
ment work improves work efficiency.
*3 *2
LabSolutions server Laboratory or office Tablet Client PC

*1
Acquisition
cotoroller PC

EDX TOC-V AA
LC GC Agilent LC, GC Thermo LC, GC Combine with
Multi-Data Registration License
to enable integrated management
of these instruments’ data and
user information.

LCMS GCMS FTIR UV RF TA

PC

A instrument B instrument

Combine with
Multi-Data Registration License
Balance PPSQ™ ICPMS Particle Size AG TOC-L to enable integrated management
Analyzer

*1 The acquisition control PC controls analytical instruments. It can also be used to send analytical instructions and perform postrun analysis, just like a client PC.
*2 If a terminal service is used, then LabSolutions software does not need to be installed on client PCs.
*3 If an iPad is used, then XenApp from Citrix must be installed.

Standalone Database System: LabSolutions DB

LabSolutions DB manages data by connecting a computer with analysis instruments, which do not have network connections. It is
recommended for facilities that do not require network connections and want to be ER/ES compliant with one computer.
*LabSolutions DB/CS is optional software that provides enhanced data integrity support. Some analysis systems and functions are not supported in contrast to the standard
workstation software GCMSsolution.

15
 Configure Optimal Analysis Systems to Meet Your Needs

For GC/MS analysis, different system configurations may be required depending on the application and
sample-introduction needs. The GCMS-QP2020 NX offers a wide variety of system configurations and
sample-introduction devices to enable an expanded range of applications.

SMCI Unit
SMCI stands for Solvent Mediated Chemical Ionization, a soft ionization method for GCMS. The headspace reagent gas from the sample
bottle is introduced into the GCMS ionization unit to be ionized, which then causes chemical ionization (CI) of the target molecule via
protonation.* Previous CI methods have required the use of flammable reagent gas cylinders, but SMCI can be carried out with a general
organic solvent such as methanol or acetonitrile, together with nitrogen or argon gas. This results in greater safety and lower running costs.

SMCI unit＋GCMS-QP2020 NX

SMCI can obtain the same results as previously existing CI methods,

but is less dependent on the compound. For example, it has been
difficult to verify the molecular weight of phthalate esters using EI
or previously existing CI method, whereas SMCI can identify the
quasi-molecular ions.

* Patent pending
The mass spectrum of bis(2-ethylhexyl)
DI-2010 Direct Inlet System phthalate (MW=390) obtained using different
ionization methods
Direct sample injection (DI) is a method in which a sample is
injected directly into the ion source without passing through the
%
gas chromatograph (GC). This is an effective method for measur-
100 EI 158
ing the mass spectra of synthetic compounds, and can be used
easily for the usual GC-MS configuration. By using this in 75

combination with Smart EI/CI ion source, EI and CI mass spectra 50 116
can easily be collected. 98
25
59
216 398 520 662 763
0
250 500 750
%
158
100 CI 679 M+H+
838
75
116
50

25 174 558 662 731

254 398
0
250 500 750
Mass Spectrum for Antibiotic Roxithromycin
Components that are thermally degradable or difficult to vaporize are not suited
to GC analysis. Their mass spectra can be obtained easily using the DI probe.

OPTIC-4 Multimode Sample Inlet System

The OPTIC-4 multimode sample inlet is a GC injection port that

enables a variety of sample injection modes for GC-MS, including
large-quantity injection, inlet derivatization, thermal desorption,
and DMI (difficult matrix introduction).
Combining this with an autosampler enables automatic replace-
ment of inserts, improving productivity in multisample analyses.

16
 HS-20 NX Headspace Analysis System

High-Sensitivity Analysis of Fragrant Components in Coffee

(×1,000,000)
Aceticacid
5.5
5.0 Furfurylalchol
4.5 Pyridine
4.0 Acetol Furfurylacetate
Methylpyrazine
3.5
3.0
2,5-Dimethylpirazine
2.5
2.0 Methylfuran
The HS-20 NX series of headspace samplers provides strong 1.5 ×5 to ×50
1.0
support for all volatile component analyses, for everything
6.0 7.0 8.0 9.0 10.0 11.0 12.0 13.0 14.0 15.0
from research to quality control.
There is a loop model capable of static headspace analysis, Trace quantities of fragrant components undetectable with
and a trap model capable of trap headspace analysis. conventional headspace samplers can be qualified and quantified
by combining the high-sensitivity, electronically cooled trap with
GC-MS.

Aqueous VOC Analysis

(×1,000) Area ratio
(×100,000)
6.0 88.00
7.5 58.00
5.0 57.00
5.0
4.0
5.0
3.0

2.0 2.5
2.5
1.0

7.5 10.0 12.5 15.0 17.5 20.0 22.5 25.0 0.0

11.5 12.0 0 50 Concentration ratio
1. 1,1-dichloroethylene, 2. dichloromethane, 3. MTBE, 4. trans-1,2-dichloroethylene,
5. cis-1,2-dichloroethylene, 6. chloroform, 7. 1,1,1-trichloroethane, 8. carbon tetrachloride,
9. 1,2-dichloroethane, 10. benzene, 11. fluorobenzene (IS), 12. trichloroethylene, SIM Chromatogram (5 µg/L) and
13. 1,2-dichloropropene, 14. bromodichloromethane, 15. 1,4-dioxane-d8 (IS), 16. 1,4-dioxane, Calibration Curve (1 to 100 µg/L) of 1,4-Dioxane
17. cis-1,3-dichloropropene, 18. toluene, 19. trans-1,3-dichloropropene, 20. 1,1,2-trichloroethane,
21. tetrachloroethylene, 22. dibromochloromethane, 23. m,p-xylene, 24. o-xylene, 25. bromoform,
26. p-bromofluorobenzene (IS), 27. 1,4-dichlorobenzene
Analysis of a trace amount of volatile organic compounds can be performed with the loop mode.

TD-30 Thermal Desorption System Sample

Silica wool
Dibutyl phthalate

Thermal desorption systems heat samples in a sample

tube and then concentrate the thermally desorbed
gases before injection into a GC-MS. They are
commonly used to measure volatile organic
compounds (VOCs) in the atmosphere or measure SVOC
trace components that are generated from plastic or
other samples. VOC
The TD-30R can accommodate 120 samples for
excellent processing capacity and offers outstanding Analysis of Gas Produced by Rubber
expandability, such as functionality for retrapping
components or for automatically adding an internal
standard substance.

17
 Pyrolysis System
High molecular compounds are subjected to pyrolysis at temperatures
of 500 °C or higher, and the obtained pyrolytic products are analyzed
with GC and GC-MS. These pyrolytic products reflect the structure of
the original high molecular compounds. Accordingly, they enable the
identification and higher order structural analysis of the polymers.
Search software utilizing a pyrolysis library assists in the identification.

Single-Shot (Thermal Desorption, TD)

EGA-MS Double Shot (Pyrolysis, PY)-GC/MS
Multi-Shot Pyrolyzer TD: 40–300 ºC (20 ºC/min)
PY: 550 ºC
Sample EGA tubing GC column
(0.1 to 1.0 mg) (2.5 m L, 0.15 mm I.D.) 30 m, 0.25 mm I.D.

Sample cup

GC oven:
GC oven: 300 ºC
Heating program
(Constant temperature)
MS
MS

Cycle 1: Thermal desorption (TD-GC/MS) - Analysis of additives

EGA Thermogram Analysis of thermogram
corresponding to temperature

Qualitative analysis using the Cycle 2: Pyrolysis (Py-GC/MS) - Analysis of resin

MS spectrum
100 10ºC/min 600ºC

Py-Screener™ Phthalate Ester Screening System

The use of phthalate esters is restricted in toys and food packaging,
and they are expected to be classified as restricted substances in the
RoHS(II) directives. This system is simple to operate, even for novices.
It consists of special software to support a series of procedures from
sample preparation to data acquisition, data analysis and
maintenance, as well as special standard samples and a sampling
toolkit.
Sample Preparation Does Not Require Organic Solvents
Standard samples and test samples can be prepared without using organic solvents.

Standard Samples Containing

Phthalate Ester for Py-GC/MS Preparation of Resin Standard Samples
(×10,000) (×1,000,000) (×100,000) (×1,000,000)
223.0 279.0 1.50 293.0 2.5 307.0
2.0
5.0 205.0 167.0 1.25
2.0
4.0 1.5
1.00
1.5
3.0
1.0 0.75
2.0 1.0
0.50
0.5 0.5
1.0 0.25

4.50 4.75 5.00 7.25 7.50 7.0 8.0 9.0 7.0 8.0 9.0 10.0
1. DBP: 162 mg/kg 2. DEHP: 2577 mg/kg 3. DINP: 4206 mg/kg 4. DIDP: 138973 mg/kg
Mass Chromatogram of Compounds Detected When Measuring a PVC Cable

18
 AOC-6000 Plus Multifunctional Autosampler System
This is compatible with three sample introduction methods: liquid
injection, HS (headspace) injection, and SPME (solid-phase
microextraction) injection. It can be controlled with GCMSsolution
software.
The overlap function, which improves the efficiency of continuous
analysis, can also be used. Automatic syringe replacement (10 µL to
1000 µL) and a stirring function enable sample dilution, the
automatic addition of internal standard substances, and the
automatic creation of calibration curve samples.

Automatic derivatization analysis of phenols̶Standard solution added water (0.0001 mg/L)

(×10,000) (×10,000) (×10,000)
5.0 1.1 200.00 1.1 200.00
4.5 166.00 1.0 185.00 1.0 185.00
4.0 151.00 0.9 0.9
3.5 0.8 0.8
3.0 0.7 0.7
2.5 0.6 0.6
0.5 0.5
2.0
0.4 0.4
1.5 0.3 0.3
1.0 0.2 0.2
0.5 0.1 0.1
7.75 8.00 8.25 8.50 10.25 10.50 10.75 11.00 10.50 10.75 11.00 11.25
Phenol 2-Chlorophenol 4-Chlorophenol

AOC-6000 Plus Control Software

GC/ MS Off-Flavor Analyzer

Information Registered in Database

Primary odor components GC/MS analytical conditions Sensory information of odor components
• Retention time information • Odor characteristics
• MS and calibration curve information • Odor threshold value

This system combines GC-MS with a database of major odor-causing

substances and sensory information (types of smells and odor
thresholds). It provides the total solution required for off-flavor analysis.
This product was developed in cooperation with Daiwa Can Company.
(×10,000) (×1,000)
2.00 195.00 2.5 344.00
28.8 pg/mg 14.4 pg/mg
1.75 210.00 329.00
1.50 167.00 2.0 301.00
1.25
1.5
1.00
0.75 1.0
Check of the Quality of a Smell 0.50
0.5
0.25
17.50 17.75 18.00 18.25 21.75 22.00 22.25 22.50
Mass Chromatogram of 2,4,6-Trichloroanisole (Left)
and 2,4,6-Tribromoanisole (Right) in Food Packaging

19
 GCMS-QP2020 NX
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