Internal Medicine

Certification Examination Blueprint

Purpose of the exam

The exam is designed to evaluate the knowledge, diagnostic reasoning, and clinical judgment skills
expected of the certified internist in the broad domain of the discipline. The ability to make appropriate
diagnostic and management decisions that have important consequences for patients will be assessed. The
exam may require recognition of common as well as rare clinical problems for which patients may consult a
certified internist.

Exam content

Exam content is determined by a pre-established blueprint, or table of specifications. The blueprint is

developed by ABIM and is reviewed annually and updated as needed for currency. Trainees, training
program directors, and certified practitioners in the discipline are surveyed periodically to provide feedback
and inform the blueprinting process.

The primary medical content categories of the blueprint are shown below, with the percentage assigned to
each for a typical exam:

Medical Content Category % of Exam

Allergy and Immunology 2%
Cardiovascular Disease 14%
Dermatology 3%
Endocrinology, Diabetes, and Metabolism 9%
Gastroenterology 9%
Hematology 6%
Infectious Disease 9%
Miscellaneous 2%
Nephrology and Urology 6%
Neurology 4%
Obstetrics and Gynecology 3%
Medical Oncology 6%
Ophthalmology 1%
Otolaryngology and Dental Medicine 1%
Psychiatry 4%
Pulmonary Disease 9%
Rheumatology and Orthopedics 9%
Geriatric Syndromes 3%
Total 100%
Exam questions in the content areas above may also include topics in Critical Care Medicine, Prevention,
Clinical Epidemiology, Ethics, Nutrition, Palliative and End-of-Live Care, Adolescent Medicine, Occupational
Medicine, Patient Safety and Substance Abuse.

Exam format

The exam is composed of up to 240 single-best-answer multiple-choice questions, of which approximately

35 are new questions that do not count in the examinee’s score. Most questions describe patient scenarios
and ask about the work done (that is, tasks performed) by physicians in the course of practice:

• Making a diagnosis
• Ordering and interpreting results of tests
• Recommending treatment or other patient care
• Assessing risk, determining prognosis, and applying principles from epidemiologic studies
• Understanding the underlying pathophysiology of disease and basic science knowledge applicable
to patient care

Clinical information presented may include patient photographs, radiographs, electrocardiograms,

recordings of heart or lung sounds, and other media to illustrate relevant patient findings. Learn more
information on how exams are developed.

A tutorial including examples of ABIM exam question format can be found at

http://www.abim.org/certification/exam-information/internal-medicine/exam-tutorial.aspx.

The primary medical categories can be expanded for additional detail to show topics that may be covered
in the exam. Each primary medical content category is listed below, with the percentage of the exam
assigned to this content area. Below each major category are subsection topics and their assigned
percentages in the exam.

Please note: The percentages below describe content of a typical exam and are approximate; actual exam
content may vary.

Allergy and Immunology 2% of Exam

Anaphylaxis <2%
General anaphylaxis
Aspirin idiosyncrasy
Stinging insect hypersensitivity
Desensitization therapy
Serum sickness
Asthma <2%
General asthma
Exercise- and cold-induced asthma
Allergic bronchopulmonary aspergillosis

2
 Nasal polyps and aspirin sensitivity
Occupational asthma
Asthma and pregnancy
Asthma mimics (including vocal cord dysfunction)
Rhinitis, sinusitis, and conjunctivitis <2%
Allergic rhinitis
Acute and chronic sinusitis
Allergic conjunctivitis
Upper airway cough syndrome
Food allergy <2%
Urticaria and angioedema <2%
Hereditary angioedema
Drug-induced urticaria and angioedema
Other causes of urticarial and anaphylaxis
Contrast-related allergy
Skin disorders <2%
Atopic dermatitis
Contact dermatitis
Drug allergy other than drug-induced urticaria and angioedema <2%
Primary immunodeficiency disorders <2%
Primary humoral immunodeficiency
Cellular immunodeficiency other than human
immunodeficiency virus (HIV) infection
Complement deficiency
Allergic complications of transfusions <2%
Hemolytic transfusions reactions
Transfusion-related acute lung injury
Transfusion-related urticaria and anaphylaxis
Autoimmune systemic disorders (including IgG4 related disorders) <2%
Mastocytosis
Allergic interstitial nephritis
Eosinophilic esophagitis
Eosinophilic pneumonia
Eosinophilic granulomatosis with polyangiitis
Hypersensitivity pneumonitis (extrinsic allergic alveolitis)

Cardiovascular Disease 14% of Exam

Hypertension (NOTE: This total includes the Hypertension content 5%
listed under Endocrinology, Diabetes, and Metabolism;
Nephrology and Urology)
Essential hypertension
Renal (including renal parenchymal, renovascular)
Coarctation of the aorta

3
 Hypertensive urgency and emergency
Undifferentiated hypertension
Pericardial disease <2%
Pericarditis
Pericardial effusion
Constrictive pericarditis
Ischemic heart disease <2%
Stable angina pectoris
Acute coronary syndrome (ACS)
ACS complications
Heart failure from ischemic cardiomyopathy
Non-cardiac chest pain
Other ischemic heart disease (coronary artery disease, spasm)
Dysrhythmias and conduction defects <2%
Conduction defects
Bradyarrhythmias
Tachyarrhythmias
Other dysrhythmias (cardiac resuscitation)
Congenital heart disease in adults <2%
Atrial septal defect and patent foramen ovale
Bicuspid aortic valve
Other congenital heart disease (patent ductus arteriosus,
ventricular septal defect, pulmonic stenosis)
Valvular heart disease <2%
Aortic stenosis
Aortic regurgitation
Mitral regurgitation
Mitral stenosis
Prosthetic heart valve
Myocardial disease <2%
Heart failure with preserved ejection fraction (HFpEF)
Myocarditis
Hypertrophic cardiomyopathy with and without obstruction
Restrictive cardiomyopathy
Dilated cardiomyopathy
Cor pulmonale
Undifferentiated myocardial disease
Endocarditis and other cardiovascular infection <2%
Endocarditis
Infections of the pericardial space
Endocarditis prophylaxis
Cardiovascular implantable device infection

4
 Vascular disease <2%
Carotid artery disease
Aorta
Peripheral arterial disease
Pulmonary vascular disease
Venous disease of the lower extremities
Superior vena cava syndrome (not due to cancer)
Syncope <2%
Reflex syncope (vasovagal and situational)
Orthostatic hypotension
Cardiac syncope (structural and electrical
Preoperative consultation <2%
No testing required
Testing indicated
Lipid disorders <2%
Antithrombotic therapy in cardiovascular disease <2%
Miscellaneous cardiovascular disease (physical examination <2%
findings, murmurs)

Dermatology 3% of Exam
Dermatitis (eczemas) <2%
Atopic dermatitis
Contact dermatitis
Photodermatitis
Stasis dermatitis
Hand dermatitis
Drug eruptions
Nummular dermatitis
Exfoliative dermatitis (erythroderma, not including
mycosis fungoides)
Seborrheic dermatitis
Dermatologic immunology <2%
Urticaria and angioedema
Leukocytoclastic vasculitis
Vascular dermatoses <2%
Erythema multiforme
Erythema nodosum
Telangiectasia
Leg ulcers
Acne and rosacea <2%
Acne vulgaris
Rosacea

5
Papulosquamous dermatoses <2%
Psoriasis
Pityriasis rosea
Lichen planus
Skin and soft tissue infections <2%
Dermatophytes
Herpes zoster and varicella
Viral exanthems other than varicella
Cellulitis, erypsipelas, and skin abscess
Necrotizing soft-tissue infections and gas gangrene
Lymphadenitis and lymphangitis
Ectoparasites (lice, scabies, and others)
Vesiculobullous dermatoses <2%
Pemphigus vulgaris
Dermatitis herpetiformis
Pigment disorders <2%
Vitiligo and other hypopigmentation disorders
Melasma (chloasma)
Acanthosis nigricans
Xeroderma pigmentosa
Photosensitivity dermatoses <2%
Porphyria cutanea tarda
Photodermatitis
Alopecia <2%
Nodules and tumors of the skin <2%
Seborrheic keratosis
Actinic keratosis
Warts, corns, and skin tags
Squamous cell carcinoma of the skin
Basal cell carcinoma of the skin
Melanoma and nevi
Mycosis fungoides
Other nodules or tumors of skin (dermatofibroma)
Cutaneous manifestations of nutritional deficiencies <2%
Disorders of the nails <2%
Environmental injury of skin <2%
Frostbite
Burns
Pressure injuries <2%
Dermatologic emergencies <2%

6
Endocrinology, Diabetes, and Metabolism 9% of Exam
Adrenal disorders <2%
Adrenal hormonal excess
Adrenal insufficiency
Adrenal masses and nodules
Thyroid disorders <2%
Hyperthyroidism
Hypothyroidism
Thyroiditis (not Hashimoto or peripartum)
Thyroid nodules and thyroid cancer
Euthyroid sick syndrome
Thyroid storm
Myxedema coma
Thyroid disease in pregnancy, peripartum,
or postpartum period
Endocrine causes of secondary hypertension <2%
Lipid disorders <2%
Hypercholesterolemia
Hypertriglyceridemia (not including chylomicronemia)
Chylomicronemia syndrome
Diet and hyperlipidemia
Ovarian disorders and female reproductive health <2%
Polycystic ovary syndrome
Premature ovarian failure
Female infertility
Hormonal therapy (contraception, postmenopausal
replacement therapy, abnormal uterine bleeding)
Testes and male reproductive health <2%
Male hypogonadism
Male infertility
Erectile dysfunction
Gynecomastia
Diabetes mellitus <2%
Type 1 diabetes mellitus
Type 2 diabetes mellitus
Diabetes mellitus and pregnancy
Complications of diabetes mellitus
Disorders of calcium metabolism and bone <2%
Hypercalcemia
Hypocalcemia (not including vitamin D deficiency)
Hyperphosphatemia
Hypophosphatemia
Paget disease
Osteoporosis

7
 Vitamin D deficiency and osteomalacia
Chronic kidney disease-mineral and bone disorder
Hypothalamic disorders <2%
Anterior pituitary disorders <2%
Pituitary tumors
Hypopituitarism
Posterior pituitary and water homeostasis <2%
Hypernatremia
Hyponatremia
Endocrine tumors and endocrine manifestations of tumors <2%
Insulinoma
Carcinoid syndrome
Other endocrine tumors or manifestations of tumors
Hypoglycemia not due to insulinoma <2%
Polyglandular autoimmune disorders <2%
Multiple endocrine hypofunction

Gastroenterology 9% of Exam
Esophageal disease <2%
Gastroesophageal reflux
Barrett esophagus
Esophageal cancer screening
Esophageal motility disorders
Medication-induced esophageal disorder
Esophageal diverticula
Esophageal strictures or webs
Gastroesophageal varices
Infectious esophagitis (Candida, herpes simplex virus,
cytomegalovirus)
Mallory-Weiss syndrome
Other esophageal disease (eosinophilic esophagitis,
esophageal rupture)
Stomach and duodenal disease <2%
Helicobacter pylori infection
Peptic ulcer disease (other than Helicobacter pylori)
Gastritis and gastropathy
Non-ulcer dyspepsia
Disorders of gastric emptying
Small intestinal disease <2%
Celiac disease
Bacterial overgrowth syndrome
Short bowel syndrome
Ischemic bowel disease

8
 Crohn disease including Crohn colitis
Gastroenteritis other than antibiotic colitis
Other small intestinal disease (diarrhea [osmotic,
post-surgical, bile salt-induced, nocturnal],
gastric bypass complications)
Colonic and anorectal disease <2%
Colorectal cancer screening
Colon polyposis syndrome and other genetic
colon cancer syndromes
Diverticular disease
Ulcerative colitis
Irritable bowel syndrome
Hemorrhoids and fissures
Antibiotic colitis
Acute appendicitis
Radiation colitis
Other colonic or anorectal disease (constipation,
fecal incontinence, neutropenic and lymphocytic colitis)
Pancreatic disease <2%
Acute pancreatitis
Chronic pancreatitis
Cystic fibrosis
Neuroendocrine tumors of the pancreas
Infections of the pancreas and pancreatic abscess
Other pancreatic disease
Biliary tract disease <2%
Cholelithiasis
Cholecystitis
Choledocholithiasis
Cholangitis
Primary sclerosing cholangitis
Sphincter of Oddi dysfunction
Liver disease <2%
Viral hepatitis
Liver abscess
Cirrhosis
Drug-induced liver disease other than acetaminophen
Autoimmune hepatitis
Primary biliary cholangitis
Cholestasis
Wilson disease
Liver disease in pregnancy
Hemochromatosis
Hepatic vein thrombosis (Budd-Chiari syndrome)

9
 Fatty liver and nonalcoholic steatohepatitis
Alcoholic hepatitis
Fulminant liver failure
Gilbert syndrome
Hepatocellular carcinoma screening
Liver transplantation
Other liver disease
Gastrointestinal complications of HIV infection <2%
Gastrointestinal hemorrhage <2%
Upper gastrointestinal hemorrhage
Lower gastrointestinal hemorrhage
Hemorrhage of unknown source

Hematology 6% of Exam
Hypoproliferative anemia <2%
Aplastic anemia
Anemia of chronic disease or organ failure
(including kidney failure)
Iron deficiency anemia
Sideroblastic anemia
Megaloblastic anemia
Lead intoxication
Hemolytic anemia <2%
Glucose-6-phosphate dehydrogenase deficiency
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Other hemolytic anemia
Hemoglobinopathies and thalassemias <2%
Thalassemias
Hemoglobinopathies
Leukocyte disorders <2%
Acute leukemia
Chronic leukemia
Leukocyte disorders (marrow infiltration, myelosuppression,
leukopenia, leukocytosis, eosinophilia)
Platelet disorders <2%
Idiopathic thrombocytopenic purpura
Qualitative defects of platelet function (drugs only)
Heparin-induced thrombocytopenia (HIT)
Essential thrombocythemia
Coagulation factor disorders and thrombotic disorders <2%
Coagulation factor deficiencies
Primary hypercoagulable states (including AT3 deficiency,
APC resistance)

10
 Antiphospholipid antibody syndrome
Undifferentiated thrombotic disorders
Porphyria <2%
Myeloproliferative disorders <2%
Polycythemia vera and other erythrocytosis
Essential thrombocythemia
Agnogenic myeloid metaplasia and myelofibrosis
Myelodysplastic syndrome <2%
Hematologic malignancies <2%
Chronic leukemias
Acute leukemia
Non-Hodgkin lymphoma
Hodgkin disease
Plasma cell disorder
Transfusion medicine (principles and complications) <2%
Indications for transfusion
Complications of transfusions
Hematologic complications of HIV infection <2%
Bone marrow transplantation (late complications only) <2%

Infectious Disease 9% of Exam

Skin and soft tissue infections <2%
Dermatophytes
Herpes zoster and varicella
Viral exanthems other than varicella
Cellulitis
Impetigo
Necrotizing soft tissue infections and gas gangrene
Lymphadenitis and lymphangitis
Diabetic foot infections
Undifferentiated skin and soft tissue infections
Central nervous system (CNS) infections <2%
Meningitis
Brain abscess
Encephalitis
Epidural abscess
Iatrogenic and postoperative CNS infections
Undifferentiated central nervous system infection
Upper respiratory tract infections <2%
Acute and chronic sinusitis
Otitis media and externa
Mastoiditis
Common cold
Pharyngitis

11
 Epiglottitis
Deep infections of head and neck
Other upper respiratory tract infections (pertussis)
Eye infections <2%
Preseptal cellulitis
Conjunctivitis
Keratitis
Endophthalmitis
Uveitis/Iritis
Orbital infections
Lower respiratory tract infections <2%
Bronchitis
Pneumonia
Lung abscess
Tuberculosis (TB)
Infections of the pleural space and empyema
Endocarditis and other cardiovascular infections <2%
Endocarditis
Infections of the pericardial space
Endocarditis prophylaxis
Suppurative thrombophlebitis
Catheter-related infections
Device and pocket infections
Hepatic infections <2%
Viral hepatitis
Liver abscess
Cholecystitis
Cholangitis
Enteric infections <2%
Esophagitis (Candida, herpes simplex virus,
cytomegalovirus)
Gastroenteritis
Infections of the pancreas and pancreatic abscess
Bacterial peritonitis
Intra-abdominal abscess other than liver or
pancreas abscess
Acquired immunodeficiency syndrome (AIDS) and
human immunodeficiency virus (HIV) infection <2%
Transmission and prevention of HIV
Prevention of opportunistic infections
Immune reconstitution inflammatory syndrome
Neurologic complications of HIV infection
Pulmonary complications of HIV infection
Gastrointestinal complications of HIV infection

12
 Hematologic complications of HIV infection
Oncologic complications of HIV infection
Rheumatologic complications of HIV infection
Cardio-metabolic complications of HIV therapy and infection
Oral complications of HIV infection
Sexually transmitted diseases and infections of reproductive organs <2%
Urethritis
Genital ulcers
Vulvovaginitis
Cervicitis
Epididymitis
Salpingitis and other infections of female pelvis
Syphilis
Human papillomavirus and anogenital warts
Undifferentiated sexually transmitted diseases
Urinary tract infections <2%
Asymptomatic bacteriuria
Cystitis and pyelonephritis
Perinephric abscess
Prostatitis
Epididymitis
Infectious arthritis <2%
Osteomyelitis <2%
Bacteremia and sepsis syndrome <2%
Fever and neutropenia
Systemic inflammatory response syndrome (SIRS)
and septic shock
Toxic shock syndrome
Undifferentiated bacteremia and sepsis syndromes
Rheumatic fever <2%
Poststreptococcal glomerulonephritis <2%
Procedure-and device-associated infections <2%
Nosocomial infections <2%
Infection control including isolation
Hospital-acquired infections and prevention
Needlestick injury and postexposure prophylaxis
Undifferentiated nosocomial infections
Prevention of infectious disease <2%
Immunization
Infection prevention and control including
isolation precautions
Needlestick injury and postexposure prophylaxis
Travel-related illness prevention
Other preventions of infectious disease

13
 Travel-related illness (fever, rash, diarrhea, and other) <2%
Infectious disease outbreaks <2%
Specific causative organisms <2%
Viral diseases
Prion diseases
Rickettsioses and ehrlichioses
Bacterial diseases
Chlamydial diseases
Mycoplasmal diseases
Mycoses (fungal infections)
Protozoan and helminthic diseases (including malaria)
Ectoparasites (including lice and scabies)
Vector-borne diseases
Fever of unknown origin <2%

Miscellaneous 2% of Exam
Primarily epidemiology <2%
Primarily ethics <2%
Primarily safety and quality improvement <2%

Nephrology and Urology 6% of Exam

Acute kidney injury <2%
Hypotension- or shock-induced acute kidney injury
Toxic kidney injury
Rhabdomyolysis
Hepatorenal syndrome
Disseminated atheroembolism
(cholesterol emboli syndrome)
Other acute kidney injury
Myeloma-induced kidney disease
Chronic kidney disease <2%
Kidney dialysis
Kidney transplantation
Strategies to prevent progression of chronic kidney disease
Undifferentiated chronic kidney disease
Tubulointerstitial disease <2%
Glomerular disorders <2%
Lupus nephritis and glomerulonephritis
Minimal change disease
Focal and segmental glomerulosclerosis
Membranous nephropathy
Membranoproliferative glomerulonephritis
IgA nephropathy
Anti-glomerular basement membrane syndrome
14
 Vasculitis and the kidney
Other glomerular disorders (post-infectious,hematuria)
Hypertension (NOTE: This total includes the Hypertension content 5%
listed under Cardiovascular Disease)
Essential hypertension
Primary aldosteronism and mineralocorticoid excess
Renovascular hypertension
Urinary tract infections <2%
Asymptomatic bacteriuria
Cystitis and pyelonephritis
Perinephric abscess
Prostatitis
Epididymitis
Nephrolithiasis <2%
Other kidney disorders <2%
Renal vein thrombosis
Obstructive uropathy (acute or chronic)
Diabetic nephropathy
Cystic kidney disease (polycystic, medullary sponge,
medullary cystic)
Urologic cancer screening <2%
Prostate disorders <2%
Benign prostatic hyperplasia
Undifferentiated prostate disorders
Other urologic disorders <2%
Testicular torsion
Scrotal and testicular nodules or masses other
than testicular carcinoma
Erectile dysfunction
Urinary incontinence <2%
Urinary incontinence in women
Urinary incontinence in men
Water and electrolyte balance <2%
Hypernatremia
Hyponatremia
Hypokalemia
Hyperkalemia
Hypercalcemia and hypercalciuria
Hypocalcemia
Hyperphosphatemia
Hypophosphatemia
Hypermagnesemia
Hypomagnesemia
Metabolic acidosis

15
 Metabolic alkalosis
Respiratory acidosis
Respiratory alkalosis
Mixed acid-base disturbance
Hematuria <2%
Glomerular cause
Non-glomerular cause

Neurology 4% of Exam
Seizures <2%
Cerebrovascular disease (without specific diagnosis)
Transient ischemic attack
Stroke
Cavernous sinus thrombosis
Other cerebrovascular disease (less common
anatomic locations, mechanisms)
Headache and facial pain <2%
Primary headache
Cluster headache
Secondary headache and facial pain
Nerve root syndromes and mechanical lesions of the spine <2%
Cervical root disease
Lumbar disc herniation, lumbosacral radiculopathy,
sciatica
Spinal stenosis
Peripheral neuropathy <2%
Acute inflammatory demyelinating polyneuropathy
(Guillain-Barre syndrome)
Carpal tunnel syndrome and other entrapment neuropathies
Meralgia paresthetica
Peroneal nerve injury
Diabetic neuropathy
Postherpetic neuralgia
Drugs and toxins
Cranial neuropathy <2%
Bell palsy and other facial nerve disorders
Disorders of eye movement from cranial
neuropathy (III, IV, VI)
Vestibular neuronitis (acute labyrinthitis)
Disorders of cerebral function <2%
Dementia
Aphasia
Medical causes of delirium

16
Movement disorders <2%
Parkinson disease and parkinsonism
Essential tremor
Other movement disorders (including other tremors,
dystonias, chorea, myoclonus, tardive dyskinesia,
restless leg syndrome)
Central nervous system (CNS) infections <2%
Meningitis
Brain abscess
Encephalitis
Epidural abscess
Neurologic complications of HIV infection
Progressive multifocal leukoencephalopathy
Autoimmune encephalitis
Central nervous system (CNS) tumors <2%
Brain tumors
Spinal cord tumors and compression
Carcinomatous meningitis
Paraneoplastic neurologic syndromes
Diseases of muscle and neuromuscular junction <2%
Myasthenia gravis and Lambert-Eaton syndrome
Polymyositis and dermatomyositis
Drug-induced myopathy
Myotonic dystrophy and other inherited myopathies
Other diseases of muscle and
neuromuscular junction
Multiple sclerosis and other demyelinating diseases <2%
Other neurologic disorders <2%
Neurocutaneous syndromes
Head injury
Spinal cord injury and disorders
Idiopathic intracranial hypertension
Motor neuron disease
Neuroleptic malignant syndrome
Cerebellar ataxias
Neuro-ophthalmology <2%
Optic nerve disorders, including optic neuritis
Pupillary abnormalities including anisocoria
Disorders of eye movement
Papilledema
Miscellaneous neurologic disorders <2%
Vertigo
Gait and balance disorders

17
Obstetrics and Gynecology 3% of Exam
Diseases of the vulva and external genitalia <2%
Breast disorders <2%
Breast nodules
Mastitis and breast-feeding
Other breast disorders (cyclic pain, nipple discharge)
Ovarian disorders <2%
Polycystic ovary syndrome
Ovarian cysts
Ovarian cancer
Uterine disorders <2%
Uterine fibroids
Endometriosis
Endometrial cancer
Cervical cancer
Vaginal disorders other than vulvovaginitis <2%
Pregnancy <2%
Hypertension in pregnancy
Asthma and pregnancy
Hyperthyroidism during pregnancy or peripartum period
Liver disease in pregnancy
Peripartum cardiomyopathy
Ectopic pregnancy
Diabetes mellitus and pregnancy
Urinary tract infections in pregnancy
Nutritional deficiencies
Menstrual disorders <2%
Dysmenorrhea
Amenorrhea
Abnormal uterine bleeding
Menopause - management, risks, and benefits of therapy <2%
Family planning and reproductive health <2%
Sexually transmitted diseases and infections of reproductive organs <2%

Medical Oncology 6% of Exam

Lung cancer (clinical presentation and diagnosis) <2%
Breast cancer <2%
Neoplasms of the head and neck <2%
Thyroid nodules and thyroid cancer
Other neoplasms of the head and neck (not thyroid cancer)
Gastrointestinal or hepatic cancer <2%
Esophageal carcinoma
Stomach cancer
Colorectal cancer
18
 Pancreatic carcinoma other than pancreatic endocrine tumors
Hepatocellular carcinoma
Gallbladder cancer
Anal cancer
Urologic cancer <2%
Renal cell carcinoma
Bladder carcinoma
Prostate carcinoma
Testicular carcinoma and tumors
Gynecologic cancer <2%
Ovarian cancer
Endometrial cancer
Cervical cancer
Vulvar cancer
Bone tumors <2%
Central nervous system (CNS) tumors <2%
Brain tumors (primary or metastatic)
Spinal cord tumors and compression
Carcinomatous meningitis
Skin cancer <2%
Squamous cell carcinoma of the skin
Basal cell carcinoma of the skin
Melanoma and nevi
Mycosis fungoides
Hematologic malignancies <2%
Chronic leukemia
Acute leukemia
Non-Hodgkin lymphoma
Hodgkin disease
Plasma cell disorder
Soft tissue cancer <2%
Oncologic complications of HIV infection <2%
Cancer of unknown primary <2%
Cancer prevention <2%
Smoking cessation
Environmental carcinogens
Inherited cancer risk
Lifestyle interventions
Oncologic emergencies <2%
Superior vena cava syndrome
Fever and neutropenia
Brain tumors
Spinal cord tumors and compression
Cardiac tamponade from neoplastic pericarditis

19
 Tumor lysis syndrome
Hypercalcemia
Complications of cancer and its treatment <2%
Pain (including neuropathy)
Dyspnea
Paraneoplastic syndromes
Lymphedema
Nausea, vomiting, diarrhea, constipation
Cardiotoxicity
Radiation toxicity
Immunotherapy
Other complications of cancer treatment
Cancer survivorship <2%
Surveillance
Second malignancies
Psychosocial and financial considerations <?

Ophthalmology 1% of Exam
Conjunctivitis <1%
Viral conjunctivitis
Bacterial conjunctivitis
Allergic conjunctivitis
Other conjunctivitis (keratoconjunctivitis sicca
[dry eyes], undifferentiated)
Glaucoma <1%
Cataracts <1%
Diseases of the cornea <1%
Corneal abrasion
Keratitis (infections of the cornea)
Neuro-ophthalmology <1%
Optic nerve disorders, including optic neuritis
Pupillary abnormalities, including anisocoria
Disorders of eye movement
Papilledema
Retinal disease <1%
Macular degeneration
Retinal detachment
Diabetic retinopathy
Amaurosis fugax
Temporal arteritis
Roth spot
Uveitis <1%

20
 Miscellaneous ophthalmologic disorders <1%
Episcleritis and scleritis
Preseptal cellulitis
Endophthalmitis
Orbital infections

Otolaryngology and Dental Medicine 1% of Exam

Disorders of the nose and paranasal sinuses <1%
Allergic rhinitis
Acute and chronic sinusitis
Disturbances of taste and smell
Epistaxis
Diseases of the ear <1%
Benign paroxysmal positional vertigo
Vestibular neuronitis and acute labyrinthitis
Meniere disease
Acoustic neuroma
Presbycusis and other hearing loss
Otitis media and externa
Cholesteatoma
Other disorders of the ear and mastoid
Diseases of the oral cavity, pharynx, and salivary glands <1%
Pharyngitis
Epiglottitis
Deep infections of head and neck
Parotid disease
Diseases of the oral mucosa and the tongue
Other disorders of the oral cavity, pharynx,
or salivary glands
Diseases of the larynx and airway <1%

Psychiatry 4% of Exam
Mood disorders <2%
Depression and suicide
Bipolar disorder
Other mood disorders (psychogenic erectile dysfunction,
premenstrual dysphoric disorder)
Eating disorders -(not including obesity) <2%
Anorexia nervosa
Bulimia
Substance use disorder <2%
Schizophrenia and delusional (paranoid) disorders <2%
Complications of drug therapy
Delusional disorder, somatic type
21
 Anxiety disorders <2%
Obsessive-compulsive disorder
Phobias
Post-traumatic stress disorders
Generalized anxiety disorder
Panic disorder
Somatoform disorders <2%
Somatic symptom disorder
Hypochondriasis
Conversion disorders
Sexual disorders and gender dysphoria <2%
Sleep disorders <2%
Insomnia
Narcolepsy
Factitious disorders <2%
Personality disorders <2%
Neuroleptic malignant disorder <2%

Pulmonary Disease 9% of Exam

Obstructive airway disease 2.5%
General asthma
Chronic bronchitis and emphysema
Occupational and environmental lung disease <2%
Organic inhalations (hypersensitivity pneumonitis)
Inorganic inhalations (pneumoconiosis)
Occupational asthma
High-altitude illness
Carbon monoxide poisoning
Restrictive lung disease other than interstitial lung <2%
and pleural disease
Pulmonary complications of obesity
Chest wall disorders
Neuromuscular disorders
Undifferentiated restrictive lung disease
Interstitial lung disease <2%
Idiopathic pulmonary fibrosis
Sarcoidosis
Radiation pneumonitis
Drug-induced interstitial lung disease
Connective tissue disorders and vasculitis
Eosinophilic pneumonia
Anti-glomerular basement membrane syndrome

22
Pulmonary vascular disease <2%
Pulmonary embolism
Idiopathic pulmonary arterial hypertension
Cor pulmonale
Superior vena cava syndrome
Hepatopulmonary syndrome
Pleural disease <2%
Noninfectious pleural effusion
Infections of the pleural space and empyema
Pneumothorax
Lower respiratory tract infections <2%
Bronchitis
Pneumonia
Lung abscess
Tuberculosis
Infection of the pleural space and empyema
Bronchiectasis <2%
Congenital lung disease <2%
Cystic fibrosis
Alpha-1-antitrypsin deficiency
Acute respiratory distress syndrome (ARDS) <2%
Fat embolism
Transfusion-related acute lung injury
Acute respiratory distress syndrome (not including fat embolism)
Lung cancer <2%
Paraneoplastic syndromes
Undifferentiated lung cancer
Sleep medicine <2%
Obesity-hypoventilation syndrome
Obstructive sleep apnea
Insomnia
Parasomnia
Management of ventilators <2%
Pulmonary complications of HIV infection <2%
Evaluation of common pulmonary symptoms 2.5%
Cough
Dyspnea
Hemoptysis
Solitary pulmonary nodule
Miscellaneous pulmonary disorders (indications for spirometry) <2%

23
Rheumatology and Orthopedics 9% of Exam
Crystal-induced arthropathy <2%
Gout
Pseudogout
Hydroxyapatite deposition disease
Regional musculoskeletal syndromes <2%
Back pain
Shoulder syndromes
Elbow syndromes
Wrist and hand syndromes
Hip and pelvic pain
Knee syndromes
Foot and ankle syndromes
Other bursitis
Spondyloarthropathies <2%
Ankylosing spondylitis
Reactive arthritis
Psoriatic arthritis
Enteropathic arthritis including arthritis with
inflammatory bowel disease
Other spondyloarthropathies
Rheumatoid arthritis <2%
General clinical presentation: Skeletal disease
Systemic manifestations
Adverse effects of antirheumatic drugs
Other topics in rheumatoid arthritis
Systemic lupus erythematosus (SLE) <2%
General clinical presentation
Specific organ system complications
Discoid lupus and other cutaneous manifestations
Drug-induced lupus
Other topics in systemic lupus erythematosus
Systemic sclerosis <2%
Scleroderma, generalized
CREST syndrome
Scleroderma and interstitial lung disease
Raynaud phenomenon
Vasculitis <2%
Polyarteritis nodosa
Eosinophilic granulomatosis with polyangiitis
Leukocytoclastic vasculitis
Large-vessel vasculitis
ANCA-associated vasculitis

24
 Other primary rheumatic disorders <2%
Dermatomyositis and polymyositis
Relapsing polychondritis
Behçet disease
Rheumatic fever
Sjögren syndrome
Fibromyalgia
Juvenile rheumatoid arthritis
Adult Still disease
Marfan and Ehlers-Danlos syndromes
Scoliosis
Arthropathy of hemochromatosis
Infectious arthritis <2%
Metabolic and other bone disease <2%
Hyperparathyroidism
Paget disease of bone
Avascular necrosis and osteonecrosis
Osteogenesis imperfecta
Osteoarthritis <2%
Sports injuries and trauma <2%
Charcot-Marie-Tooth Disease <2%
Mixed connective tissue disease <2%
Select topics in Rheumatology <2%

Geriatric Syndromes 3% of Exam

Pressure injuries <2%
Venous ulcers and chronic wounds <2%
End-of-life and palliative care of the elderly <2%
Ethics in the elderly <2%
Assessment of decisional capacity and competency and
surrogate decision-making in the elderly
Constipation in the elderly <2%
Disorders of swallowing in the elderly <2%
Urinary tract infections in the elderly <2%
Incontinence in the elderly <2%
Dementia in the elderly <2%
Delirium in the elderly <2%
Dizziness and vertigo in the elderly <2%
Nutrition in the elderly <2%
Ophthalmology in the elderly <2%
Cataracts
Age-related macular degeneration
Ischemic optic nerve or retinal disease other
than giant cell arteritis

25
 Glaucoma
Psychiatry in the elderly <2%
Depression in the elderly
Sleep disorders in the elderly
Neuropsychological testing of the elderly
Hip fracture in the elderly <2%
Common foot problems in the elderly <2%
Principles of the geriatric assessment <2%
Rehabilitation and the elderly <2%
Other primary geriatric topics <2%
Clinical pharmacology and aging
Epidemiology and aging
Nursing home care
Home care
Presbycusis and hearing loss in the elderly
Elder mistreatment
Falls
Sexual function in the elderly

January 2023

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