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6.1 Melnic Lucia Studiul

The document analyzes ophthalmic pharmaceutical formulations used in medical practice. It studied industrial and magistral (compounded) eye drop formulations used at the "Vasile Procopisin" University Pharmaceutical Center (UPC) production department. The most commonly prescribed magistral formulation was identified. A method for quantitative analysis of compounded eye drops was developed that is simple, fast and useful. Ophthalmic formulations allow localized drug effects in the eyes while avoiding systemic side effects, and local ocular therapy has the advantages of rapid and direct action with low drug concentrations.

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51 views1 page

6.1 Melnic Lucia Studiul

The document analyzes ophthalmic pharmaceutical formulations used in medical practice. It studied industrial and magistral (compounded) eye drop formulations used at the "Vasile Procopisin" University Pharmaceutical Center (UPC) production department. The most commonly prescribed magistral formulation was identified. A method for quantitative analysis of compounded eye drops was developed that is simple, fast and useful. Ophthalmic formulations allow localized drug effects in the eyes while avoiding systemic side effects, and local ocular therapy has the advantages of rapid and direct action with low drug concentrations.

Uploaded by

Iurii
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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STUDY AND ANALYSIS OF OPHTHALMIC PHARMACEUTICAL FORMULATIONS

USED IN MEDICAL PRACTICE


Melnic Lucia, Solonari Rodica, Guranda Diana, Diug Eugen
Department of Drug Technology, "Nicolae Testemitanu" State University of Medicine and Pharmacy,
Chisinau, Republic of Moldova
Introduction: According to WHO data, eye diseases Material and methods: There was analyzed the
are increasingly common in both adults and children, magistral drug preparation of “Vasile Procopisin”
and the lack of adequate treatment can lead to serious UPC’s production department used in the treatment
complications. of eye diseases from a technological and
biopharmaceutical point of view.
Keywords: Ophthalmic formulations, Results: Data from specialized literature show that
prescriptions’ repeatability magistral the most commonly used pharmaceutical formulations
drug preparation. in ophthalmic practice are eye drops. There were
analyzed all magistral formulations in the production
department and there was identified the most often
Purpose: The research objective was to study the prescribed one. The repeatability of the prescriptions
industrial and magistral ophthalmic formulations used in eye diseases took place during September -
used in medical practice, with the reproduction of December 2019. There was developed the method of
the most common pharmaceutical formulation quantitative analysis of compound eye drops prepared
prepared within "Vasile Procopisin" University in the production department. The method is simple,
Pharmaceutical Center (UPC) and to conduct their fast and useful in use.
qualitative-quantitative control. Conclusions: Ophthalmic formulations allow the
localization of the effect of medicinal substances in
the eyes, thus avoiding unwanted systemic effects,
and local therapy of the ocular area has the
advantage of a rapid and direct action, with low
concentrations of drugs.

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