Window Period: Terms Related To Hiv /aids
Window Period: Terms Related To Hiv /aids
Window Period: Terms Related To Hiv /aids
WINDOW PERIOD
Time period between initial HIV infection and the development of a measurable
immunological response to the infection
WASTING SYNDROME
It is defined as 10 percent weight loss accompanied by 30 days of fever or diarrhea
It include severe weight loss of appetite.
PNEUMOCYSTIS PNEUMONIA
It is serious infection that causes inflammation and fluid buildup in the lungs caused
by fungus called pneumocystis.
KAPOSI SYNDROME
A cancer that causes lesions to grow in the skin, soft tissues, internal organs, mucous
membrane of nose and throat.
ENCEPHLOPATHY
A term used for brain disease that alter the brain function and structure, causes are
tumors, infections.
PYOMYOSITIS
It is a rare muscle bacterial infection, includes fever, pain, tenderness, abscess
formation.
ULCERATIVE STOMATITIS
It is an immune mediated disorder characterized by oral erosions and ulcers.
• IMMUNE SYSTEM
Immune system protects and defends the body from infections. White blood cells are the
most important part, which fight and destroys bacteria, fungi, viruses that enter the body.
DEFINITION OF HIV/AIDS
H=HUMAN
I=IMMUNODEFICIENCY
V=VIRUS
WHAT IS AIDS
A=AQUIRED
I=IMMUNE
D=DEFICIENCY
S=SYNDROME
INTRODUCTION
AIDS is the ultimate clinical consequence of HIV. it is a retrovirus that primarily effect the
vital organs of human immune system such ads CD4 cells if the number of CD4 cells is
below 200 then immunity is lost.
AIDS is the last stage of HIV infection that occurs when the immune system of the body is
badly disturbed because of virus.
ETIOLOGY
Unprotected sex
Sharing needles
Occupational exposure
Infected blood
During pregnancy
Kissing
Hugging
Swimming
Sharing
Cooking
Insect bites
Transplant procedures
Occupational
Tattoo
IDU (INJECTION DRUG USERS)
Poverty
PATHOPHYSIOLOGY
Human mortalities
HIV LIFE COMPLEX
ATTACHMENT
UNCOATING
DNA SYNTHESIS
INTEGRATION
TRANSCRIPTION
TRANSLATION
CLEAVAGE
BUDDING
CLINICAL MENIFESTATIONS
Clinical stage 1
Clinical stage 2
Clinical stage 3
Clinical stage 4
CLINICAL STAGE 1
Asymptomatic, lymphadenopathy
CLINICAL STAGE 2
Unexplained weight loss, recurrent respiratory tract infection,
Recurrent oral ulceration, dermatitis, fungal nail infection.
CLINICAL STAGE 3
Unexplained severe weight loss, chronic diarrhea, persistent fever,
Oral candidiasis, pulmonary tuberculosis, bacterial infection,
Ulcerative stomatitis, unexplained anemia
CLINICAL STAGE 4
Wasting syndrome, pneumocystis pneumonia, extra pulmonary tuberculosis, KAPOSI
SARCOMA, HIV encephalopathy, meningitis,
Cervical carcinoma, nephropathy and cardiomyopathy.
DIAGOSTIC EVALUATION
It is the test to detect antibodies to HIV ANTIGEN in the patient blood using plates
If positive, the ELISA test is repeated because false positive can occur
If the ELISA test is again positive, the western blot test is done to detect the presence of
antibodies
2. WESTERN BLOT
This test includes separation of blood proteins and detect the specific called HIV
ANTIBODIES that indicates an HIV infection. It is used to confirm a positive ELISA, and
combine tests are 99.9% accurate.
HIV ANTIGEN TEST
1. P24 ANTIGEN
This test detect the protein of presence of the p24 protein of HIV
2. DNA PCR [polymerase chain reaction]
The DNA PCR Test looks for HIV DNA in white blood cells. PCR is sensitive enough to
detect HIV
COMPLICATIONS
• Patient education
• Lifestyle modifications
• Take rest diet rich in proteins and vitamins
• Smoking cessation
• Alcohol cessation
• Regular exercise or yoga
NURSING ASSESSMENT
a. History collections
b. Review patient present complications
c. Assess patient knowledge about HIV
d. Evaluate nutritional pattern
e. Assess respiratory rate, general health status
f. Check for lesions , ask for bowel pattern
g. Check orientation.
NURSING DIAGNOSIS
PREVENTION
o Use treatment as prevention
o Education
o immunizations
o Immigration regulations
o Use condom
o Use of clean needle
o Supportive car
o Use standard precautions
Hand hygiene
Protective equipment gloves, mask, gown
Patient placement
Avoid sharing clothes
2) Seltzer S.C. Bare B.G., Hinkle J.L., Cheever K. H. Brunner and Siddhartha’s textbook
of medical surgical nursing 11 edition. Lippincott Williams and Wilkins publishers,
page no 845-848