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Cor Pulmonale PATHOPHYSIOLOGY

This document discusses the pathophysiology of cor pulmonale, which is caused by pulmonary hypertension due to lung disease. It lists predisposing factors like age, sex, and heredity that can increase risk. Precipitating factors include lifestyle, diet, COPD, heart issues, and smoking history. Hypoxia and respiratory acidosis occur, causing pulmonary vasoconstriction and increased pulmonary artery pressure over time. This leads to right ventricular strain, enlargement, and eventually failure. Symptoms include edema, liver enlargement, shortness of breath, and confusion.

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Chloie Marie Rosalejos
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460 views2 pages

Cor Pulmonale PATHOPHYSIOLOGY

This document discusses the pathophysiology of cor pulmonale, which is caused by pulmonary hypertension due to lung disease. It lists predisposing factors like age, sex, and heredity that can increase risk. Precipitating factors include lifestyle, diet, COPD, heart issues, and smoking history. Hypoxia and respiratory acidosis occur, causing pulmonary vasoconstriction and increased pulmonary artery pressure over time. This leads to right ventricular strain, enlargement, and eventually failure. Symptoms include edema, liver enlargement, shortness of breath, and confusion.

Uploaded by

Chloie Marie Rosalejos
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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PATHOPHYSIOLOGY of COR PULMONALE

Precipitating Factors:
Predisposing Factors:
 Lifestyle
 Diet
 Age
 COPD
 Sex (Male)
 History of MI
 Heredity  History of CAD
Etiology

(Unknown)

Hypoxia and hypoxemia Respiratory Acidosis

Hypoxic Pulmonary
Arterial
vasoconstriction

Decrease in pulmonary
vascular bed

Increase pulmonary artery


pressure

Increase resistance in
pulmonary circulatory system

Pulmonary
hypertension

Increased right loud second heart


ventricular afterload sound

Right ventricular
Enlarged heart
hypertrophy

Right ventricular failure

Increased venous Increased capillary hydrostatic Further impairment


pressure pressure throughout the of blood circulation
venous system

a
b c
a b c

Jugular venous Retention of fluid


distension
Easy confusion
fatigability
Edema of the lower
extremities
Distended Enlarged
neck veins palpable liver

Increase pressure
within the portal
Increase pressure on Somnolence
vessels
the diaphragm

Shortness of breath Ascites

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