Balacano, John Glenn Drug Study
BSN -4A
Drug Mode of Action Indication Contraindication Adverse Drug Nursing
Name Reaction Responsibilities
Etoricoxib Selectively inhibits Short-term treatment of Active peptic Hypersensitivity Assess client for
(Arcoxia) cyclo-oxygenase- 2 moderate pain ulceration or active Reactions: history of allergic
(COX-2) COX-2 gastro-intestinal Swelling of the reaction to Arcoxia
120mg/ta which is an isoform For the symptomatic (GI) bleeding. face, lips, tongue or for previous
b every 4 of the enzyme that relief of osteoarthritis or throat which heart failure, heart
hours as has been postulated (OA), rheumatoid Patients who have may cause attack, bypass
needed for to be primarily arthritis (RA), experienced difficulty in surgery, angina,
pain responsible for the ankylosing spondylitis, bronchospasm, swallowing or peripheral arterial
synthesis of and the pain and signs acute rhinitis, nasal breathing disease, or transient
mediators of pain, of inflammation polyps, ischaemic attack.
inflammation, and associated with acute angioneurotic Insomnia or
fever. gouty arthritis. oedema, urticaria, increased anxiety Monitor blood
or allergic-type pressure regularly
Affects central reactions after Severe increase in while taking this
nervous system taking blood pressure medication.
functions towards acetylsalicylic acid
fever induction, or NSAIDs Confusion, Take medication
pain perception and including COX-2 Hallucinations with a glass of
cognitive function. inhibitors. water to avoid
dehydration.
Decreased
Does not inhibit Severe hepatic Platelets
COX-1 at thereby Arcoxia may be
dysfunction (serum
has no effect on taken regardless of
albumin <25 g/l or Atrial Fibrillation
gastric food intake.
Child-Pugh score or abnormal
prostaglandin ≥10). rhythm of the
synthesis and on Stop the medication
platelet function heart immediately if
Estimated renal gastrointestinal
creatinine Heart failure lesions occur.
clearance <30
ml/min. Stomach pain or
Inflammatory Stomach ulcers
bowel disease. that may become
serious and may
Patients with bleed, and may
hypertension occur at any time
whose blood during use and
pressure is without warning
persistently
elevated above
140/90mmHg and
has not been
adequately
controlled.
Established
ischaemic heart
disease, peripheral
arterial disease,
and/or
cerebrovascular
disease.
Drug Name Mode of Action Indication Contraindication Adverse Drug Nursing
Reaction Responsibilities
Betahistine exerts a relaxant Antivertigo drug Hypersensitivity to Mild gastric Instruct
diHCl action on the betahistine diHCl complaints patient that
precapillary or to any of the drug should
16 mg/ tab sphincters of the excipients of Serc skin rashes be taken with
Meniere's disease
Per orem microcirculation of food.
Thrice a the inner ear, and Patients with
day thereby increases pheochromoc
the blood supply to ytoma or
the stria vascularis bronchial
of the labyrinth asthma
should be
treated with
extra care
Drug Name Mode of Action Indication Contraindication Adverse Drug Nursing
Reaction Responsibilities
Norgesic Anticholinergic Relief of painful Contraindication to Nausea and Provide additional
Forte drug/agent is a skeletal muscle spasm Norgesic/Norgesic vomiting, dry measures to relieve
(Orphenadri substance that associated with chronic Forte result from mouth, blurring of discomfort – heat,
ne citrate) blocks the low back pain, sprains the parasypatolytic vision, insomia, rest for the muscle,
action of
neurotransmitter and strains, prolapsed orthostatic positioning.
orphenadrine. it
acetylcholine in intervertebral disc, should not be hypotension,
2. Discontinue the
(2-tab Per the CNS and PNS. muscle injury, non- given to patients lightheadedness,
drug at any sign of
Orem Thrice May be related on articular rheumatism, with glaucoma, stomach cramps,
hypersensitivity
A Day) part to its analgesic ‘whiplash’ injuries, prostatic constipation,
reaction or liver
effects also acute torticollis, tension hypertrophy, dizziness and
bladder neck dysfunction.
possess headache, restlessness may
obstruction or
anticholinergic dysmenorrheal and myasthema gravis. occur in some 3. Monitor
activity. other acute or chronic It should be used patients susceptible respiratory status.
painful muscular with caution in to the
patients with 4. Monitor for
conditions. parasympatholytic
tachycardia. adverse effects.
action or
Norgesic/Norgesic orphenadrine.
5. Monitor the
Forte is not
Rarely, rash may effectiveness of
recommended for
children below 12 also occur. comfort measures
years. and compliance
with the regimen.
6. Patients should
be cautioned to
avoid alcohol while
taking this muscle
relaxant drug.
Generic Classificatio Mechanism Indications Contraindication Adverse Reactions Nursing
name of Drug
n Action s Responsibilities
Generic: Analgesics Antipyretic: Temporary Gastrointestinal ASSESSMENT
caloric
(Non-opioid Reduces relief of pain problems
Paracetamol undernutrition 1. Assess patient’s
Antipyretics fever by and
pain or temperature
acting discomfort acute liver failure before therapy and
directly on from Allergic skin
regularly thereafter.
the headache, liver problems reactions
Ordered: hypothalamic fever, cold, 2, Asses patient’s
heat- flu minor severe renal drug history and
1 tab by regulating muscular impairment
methemoglobinemia calculate total daily
mouth PRN center to aches, , dosage accordingly.
for Fever of Shock
cause overexertion,
37.8 C 3. Be alert for signs
vasodilation menstrual acetaminophen of reactions
and cramps, overdose hemolytic anemia
sweating, toothache, and drug
which helps minor Acute interactions.
dissipate arthritic pain. Inflammation of
heat. the Liver due to 4. Assess patient’s
Hepatitis C Virus and family’s
knowledge of drug
Allergies: therapy.
Acetaminophen
