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Ketamine

Ketamine is used for short-term analgesia and anesthesia induction. It works by blocking NMDA receptors in the central nervous system, stimulating the sympathetic nervous system. Common side effects include vivid dreams, confusion, hallucinations and increased blood pressure. It should not be used in patients with hypertension, heart disease, aneurysms or hyperthyroidism due to cardiovascular stimulation. Nursing management includes monitoring vital signs and providing supportive care.

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Lorraine
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6K views1 page

Ketamine

Ketamine is used for short-term analgesia and anesthesia induction. It works by blocking NMDA receptors in the central nervous system, stimulating the sympathetic nervous system. Common side effects include vivid dreams, confusion, hallucinations and increased blood pressure. It should not be used in patients with hypertension, heart disease, aneurysms or hyperthyroidism due to cardiovascular stimulation. Nursing management includes monitoring vital signs and providing supportive care.

Uploaded by

Lorraine
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Info & Mechanism Adverse Contraindicatio Nursing

Drug Side Effects


Indication of Action Effects n Management
To provide Vivid, often
analgesia for unpleasant Alcohol
painful
dreams, Patients with Ventilatory
procedures of
confusion, Other hypertension, support
short duration.
hallucinations, sedatives ischaemic heart
Indicated for delirium, disease, CVS
the induction It depresses the Stimulants monitoring
central nervous involuntary aneurysms and
of anesthesia hyperthyroidism
system by movement
prior to the blocking the Symptomatic
administration effects of the during (due to CVS
KETAMI of other excitatory recovery stimulation). treatment
neurotransmitter,
NE general glutamic acid at time.
N-methyl d- anesthetic the NMDA Patients with
aspartate agents. receptors. It is a
increased
cardiovascular Drug
receptor stimulant, causing Rare Effects: intracranial
antagonist Indicated to an increase in B.P, Toxicity:
supplement heart rate and
tension and
low-potency cardiac output due Increase in psychotic
Routes: to sympathetic Increased
agents, such skeletal disorders.
I.V., I.M., as nitrous
stimulation. It cardiac
increases cerebral muscle tone
Continuous oxide. blood flow. stimulation,
and
infusion. arrhythmias
Onset of action is fasciculations.
Ketamine is 1-3 minutes. and
Shelf life: used to Duration of respiratory
2 Years manage pain analgesia is 40
minutes. Duration depression.
among horses
of anaesthesia is
and other
Storage: 15 minutes.
large animals, Duration of
Airtight though it has amnesia is 1-2
containers less effect on hours. It is
subsequently
bovines. redistributed to
other tissues. It is
metabolized in the
liver and is
excreted in urine
and bile.

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