XN-1500

Count. Smear. Stain. All-in-one haematology.

www.unlimited-possibilities.com
Differentiated counting.
Consistent smears.
Advanced diagnostics. Staining

Blood is remarkably precious. It carries all our bodies need to survive. The XN-1500 system will certainly make your life
It also bears the body’s signals that things are not quite as they should be. easier. For the first time, we have combined our
market-leading XN-Series analyser with a brand-new
At Sysmex, we have made it our task to help you identify these signals slide maker/stainer in an all-in-one workstation.
as easily and efficiently as possible. Whatever size laboratory you Should an analysis result lead to a smear, it is
Counting
performed without manual intervention. The result?
operate or own. Consistent smears with a beautiful cell monolayer
that make further microscopic diagnostics as easy Far more than just a blood count
and powerful as possible. Add a DI-60, our digital
All our haematology expertise in an affordable solution – imaging analyser, and microscopic analysis can be
Sysmex haematology has moved well beyond
mere cell counting. By directly addressing
the all-in-one XN-1500. performed automatically, too. issues we know you face in the laboratory, our
applications and advanced clinical parameters
eliminate key issues common with non-XN
analysers or other technologies.
Benefits at a glance
n Seamless workflow
You can now offer best-in-class diagnostics
and upgrade your system as your or your
n As primary analyser or back-up customers’ demands change. For example, add
n Complete standardisation:
the advanced reticulocytes parameters (RET),
which offer a valuable contribution to anaemia
n consistency of blood smear preparation
and staining
Smears: enhance your workflow, diagnosis by highlighting the complete picture
of erythropoiesis and its further development.
standardisation and result quality
n runs paediatric samples like all others thanks The extensive spectrum of results offered only
to low aspiration volume by Sysmex is opening doors to clinical insight
Challenged by workflow and efficiency issues, you previously not available. Modular and scalable,
n Short turnaround time, less time needed for have to get your smear workflow just right. Ideally, The XN-1500 is an all-in-one your investment is future-proof.
preparing slides
the need for smears is reduced up front by intelligent system: from sample analysis
n Fewer biohazardous procedures technology, flagging and rule setting. Yet when Slide-making to slide-making and staining. For full capability details of the XN, we refer
you to the XN-Series brochure or our website.
n Eliminates manual handling steps prone to errors smears are required, they should be of the highest
quality and consistency and preferably automatic –
n Simplified operation suitable for night shifts
thereby decreasing TAT and manual errors.
n Increases your laboratory’s productivity

As a primary analyser for mid-size laboratories,

On-board rules
or as a back-up for larger systems, the XN-1500
haematology workstation provides an automated,
seamless workflow that eliminates most manual
procedures.
 Physicians and clinicians get to know more XN-CBC: more than the standard CBC (included)
n always includes nucleated red blood cells (NRBC%, NRBC#)
added value
and can act faster
XN-CBC
n auto-corrects WBC counts by metrological separation from NRBC

Our research into the interdependencies

between haematological cell counts and XN-DIFF: more than a standard 5-part differential (included)
n always includes IG%, IG#
added value
pathologies is helping us to make huge
XN-DIFF
advances in delivering clinical insight. Treating n uses special ‘low WBC’ mode for critically low cell counts

physicians gain faster, more detailed insight n optional licence: Extended Inflammation Parameters

into patients’ illnesses and can confidently (RE-LYMP, AS-LYMP, NEUT-GI, NEUT-RI)
deliver more effective diagnoses, treatment
monitoring and screening. RET: extensive red cell diagnostics (optional)
n quantifies mature and immature reticulocytes (RET%, RET#, IRF)
added value

RET
Monitoring thrombocytopenia, for example, n determines the haemoglobinisation of reticulocytes (RET-He)

is tricky using solely platelet counts. With our n determines more quantitative and prognostic anaemia parameters

immature platelet count, non-responders to (RBC-He, Delta-He, HYPO-He, HYPER-He, FRC, RPI)
ITP treatment can be identified and therapy n optional: management of increased MCHC (CBC-O*)

can be modified quickly. Another example is

understanding real-time immune status. Using PLT-F: specific platelet diagnostics (optional)
our Extended Inflammation Parameters, you added value
n quantifies platelets precisely, even in the thrombocytopenic range
PLT-F
can now differentiate between different types Need-based, differentiated counting n provides accurate platelet counts, even with RBC interferences

of immune response to identify the stage with the XN module and giant platelets
of an infection. Monitoring patients with n quantifies immature platelets: fraction (IPF) and absolute count (IPF#)

inflammatory diseases and successful therapy The XN analyser offers high diagnostic capabilities as n improves your platelet workflow with the ‘TWO’* algorithm

limits the use of antibiotics. Only from Sysmex. standard, including nucleated red blood cells in every
CBC count. You save time and resources thanks to the WPC: specific white cell diagnostics (optional)
advanced flagging that reduces the need for smears while n detects white pathological and precursor cells

the on-board trigger criteria automate their processing. n helps you confidently exclude malignancies in combination

with XN-DIFF
Be confident – rules, regulations, Take advantage of optional parameters for anaemia n allows multi-parametric assessment of reactive conditions
accreditation, etc. diagnostics, automated body fluid analysis, or high- n optional: XN Stem Cells

precision platelet counts that deliver reliable results

Increasingly we’re all faced with rules, regulations even with extremely low counts. Information provided XN-BF: automated analysis of body fluids (optional)

Know more.
and accreditation challenges. Thanks to embedded by progenitor cell analysis enables a more cost-effective added value
n analyses cerebrospinal fluid, synovial fluid, pleural fluid and
software and use of our Extended IPU, you have XN-BF
yet equally reliable apheresis process. others 24/7
full transparency and full control over how you n counts and differentiates cells (RBC-BF, WBC-BF, PMN%, PMN#,

Decide with confidence.

manage your pre- and post-analytical data. Safety Our optional Extended IPU provides further support for MN%, MN#, TC-BF, HF-BF)
and traceability come first. We want you to be determining the causes of thrombocytopenia. You can
confident everything is under control; internally also integrate manual differentials, digital imaging or a For more details on the clinical insights that can be gained with the
and externally. You can be.

Act faster.
count pad, and solve the challenge of determining the XN, we refer you to our XN-Series clinical cards and white papers on
cause of an increased MCHC with our ‘CBC-O’* solution. www.sysmex-europe.com/whitepapers.

*available with Extended IPU

Standardisation from smear preparation
to stained blood smear

The SP-50 is equipped with the very latest technology to

create a consistent, high-quality smear. With its intelligent
wedge method, you define settings for sample volume,
speed and angle of the spreader blade. The SP-50 produces
standardised blood films regardless of the blood sample’s
consistency. Auto-adapted to the HCT value of each blood
sample, the length of the smear guarantees a particularly
wide monolayer area for performing the blood cell
differential count.

Blood cells are special and deserve

the best treatment

It now needs to be stained properly, which means that Consistent, high-quality slides are the
cytoplasmic and nuclear details of the various cell types backbone of diagnostic haematology since
blood cell morphology differentials depend
need to be accentuated. The SP-50 handles the RAL Classic
directly on the quality of the blood smear.
staining reagents for May Grünwald, Giemsa and Wright This again depends on both the spreading
stains perfectly. A wide variation of staining reagents of the blood on a glass slide and properly
reveal the cell characteristics fully, whether under a manual Manual tasks? No more. staining the cells.
microscope or with digital microscopy. To complete the
automation from start to finish, you can choose to add our Since the counter and slide-maker/stainer are connected With the XN-1500, results of the automated
cell count as well as the morphology blood
digital imaging analyser – the DI-60. physically, the XN-1500 eliminates most manual tasks.
smear review are highly comparable and
Simply place the sample in a rack and you can remove the reproducible. This delivers the greatest cell
stained blood smear at the end. That’s it. recognition by the onlooker for an accurate
This also means you minimise work with biohazardous differential count and better diagnostics.
material and dangerous staining solutions.

Also for night and weekend shifts

Clinicians are calling for accurate and reliable results for

their patients around the clock, with a guaranteed short
turnaround time. The simple operation of the XN-1500’s
blood count and smear workflow means it can be operated
easily by night or weekend staff.
Technical specifications
Measurement principles WBC DIFF/RET/PLT-F/WPC: fluorescence flow cytometry
RBC/PLT: hydrodynamically focussed impedance
HGB: cyanide-free SLS haemoglobin
Throughput XN: up to 100 samples/h in whole blood (WB) mode,
up to 40 samples/h in body fluid (BF) mode
SP-50: up to 30 slides/h in standard mode,
up to 75 slides/h with the optional high-throughput licence
Aspiration volume XN: 88 μL in whole blood (WB) mode and body fluid (BF) mode
SP-50: 70 μL for smear preparation in auto mode,
38 μL for smear preparation in manual mode
Analysis parameters
Whole blood WBC, NRBC%, NRBC#, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, MicroR%, MacroR%, PDW, MPV,
P-LCR, PCT, NEUT%, NEUT#, LYMPH%, LYMPH#, MONO%, MONO#, EO%, EO#, BASO%, BASO#, IG%, IG#
With RET (optional) RET%, RET#, IRF, LFR, MFR, HFR, RET-He, RBC-He, Delta-He, HYPO-He%, HYPER-He%, PLT-O
With PLT-F (optional) PLT-F, IPF, IPF#
With WPC (optional) Extended Inflammation Parameters licence: NEUT-GI, NEUT-RI, RE-LYMP%, RE-LYMP#, AS-LYMP%, AS-LYMP#
XN Stem Cells licence: HPC%, HPC#
Body fluids with XN-BF WBC-BF, RBC-BF, MN%, MN#, PMN%, PMN#, TC-BF#
(optional)
Staining protocols (SP-50) May Grünwald – Giemsa, Wright – Giemsa, Wright
Data storage capacities (XN) Results: 100,000 samples
Patient information: 10,000 records
QC files: 99 files (300 plots per file)
Reagent replacement history: 5,000 records
X-bar control (L-J control): 300 plots x 94 files
X-barM control: 300 plots x 5 files
Dimensions / weights
w x h x d [mm/kg]
Main unit (including sampler) 1006 x 1053 x 855 / approx. 211
Pneumatic unit (PU) 280 x 355 x 400 / approx. 17
(two PUs are required per XN-1500)
Wagon (optional) 1161 x 1115 x 706 / approx. 137

Authorised representative: Sysmex Europe GmbH

ZE001702.EN.C.11/17

Bornbarch 1, 22848 Norderstedt, Germany · Phone +49 40 52726-0 · Fax +49 40 52726-100 · info@sysmex-europe.com · www.sysmex-europe.com
Manufacturer: Sysmex Corporation
1-5-1 Wakinohama-Kaigandori, Chuo-ku, Kobe 651-0073, Japan · Phone +81 78 265-0500 · Fax +81 78 265-0524 · www.sysmex.co.jp
You will find your local Sysmex representative’s address under www.sysmex-europe.com/contacts